ICAM3 (NM_002162) Human Untagged Clone

CAT#: SC128181

ICAM3 (untagged)-Human intercellular adhesion molecule 3 (ICAM3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ICAM3
• Synonyms: CD50; CDW50; ICAM-R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128181 sequence for NM_002162 edited (data generated by NextGen Sequencing)
  ATGGCCACCATGGTACCATCCGTGTTGTGGCCCAGGGCCTGCTGGACTCTGCTGGTCTGC
  TGTCTGCTGACCCCAGGTGTCCAGGGGCAGGAGTTCCTTTTGCGGGTGGAGCCCCAGAAC
  CCTGTGCTCTCTGCTGGAGGGTCCCTGTTTGTGAACTGCAGTACTGATTGTCCCAGCTCT
  GAGAAAATCGCCTTGGAGACGTCCCTATCAAAGGAGCTGGTGGCCAGTGGCATGGGCTGG
  GCAGCCTTCAATCTCAGCAACGTGACTGGCAACAGTCGGATCCTCTGCTCAGTGTACTGC
  AATGGCTCCCAGATAACAGGCTCCTCTAACATCACCGTGTACAGGCTCCCGGAGCGTGTG
  GAGCTGGCACCCCTGCCTCCTTGGCAGCCGGTGGGCCAGAACTTCACCCTGCGCTGCCAA
  GTGGAGGATGGGTCGCCCCGGACCAGCCTCACGGTGGTGCTGCTTCGCTGGGAGGAGGAG
  CTGAGCCGGCAGCCCGCAGTGGAGGAGCCAGCGGAGGTCACTGCCACTGTGCTGGCCAGC
  AGAGACGACCACGGAGCCCCTTTCTCATGCCGCACAGAACTGGACATGCAGCCCCAGGGG
  CTGGGACTGTTCGTGAACACCTCAGCCCCCCGCCAGCTCCGAACCTTTGTCCTGCCCGTG
  ACCCCCCCGCGCCTCGTGGCCCCCCGGTTCTTGGAGGTGGAAACGTCGTGGCCGGTGGAC
  TGCACCCTAGACGGGCTTTTTCCAGCCTCAGAGGCCCAGGTCTACCTGGCGCTGGGGGAC
  CAGATGCTGAATGCGACAGTCATGAACCACGGGGACACGCTAACGGCCACAGCCACAGCC
  ACGGCGCGCGCGGATCAGGAGGGTGCCCGGGAGATCGTCTGCAACGTGACCCTAGGGGGC
  GAGAGACGGGAGGCCCGGGAGAACTTGACGGTCTTTAGCTTCCTAGGACCCATTGTGAAC
  CTCAGCGAGCCCACCGCCCATGAGGGGTCCACAGTGACCGTGAGTTGCATGGCTGGGGCT
  CGAGTCCAGGTCACGCTGGACGGAGTTCCGGCCGCGGCCCCGGGGCAGCCAGCTCAACTT
  CAGCTAAATGCTACCGAGAGTGACGACGGACGCAGCTTCTTCTGCAGTGCCACTCTCGAG
  GTGGACGGCGAGTTCTTGCACAGGAACAGTAGCGTCCAGCTGCGAGTCCTGTATGGTCCC
  AAAATTGACCGAGCCACATGCCCCCAGCACTTGAAATGGAAAGATAAAACGAGACACGTC
  CTGCAGTGCCAAGCCAGGGGCAACCCGTACCCCGAGCTGCGGTGTTTGAAGGAAGGCTCC
  AGCCGGGAGGTGCCGGTGGGGATCCCGTTCTTCGTCAACGTAACACATAATGGTACTTAT
  CAGTGCCAAGCGTCCAGCTCACGAGGCAAATACACCCTGGTCGTGGTGATGGACATTGAG
  GCTGGGAGCTCCCACTTTGTCCCCGTCTTCGTGGCGGTGTTACTGACCCTGGGCGTGGTG
  ACTATCGTACTGGCCTTAATGTACGTCTTCAGGGAGCACCAACGGAGCGGCAGTTACCAT
  GTTAGGGAGGAGAGCACCTATCTGCCCCTCACGTCTATGCAGCCGACAGAAGCAATGGGG
  GAAGAACCGTCCAGAGCTGAGTGA
  
  Clone variation with respect to NM_002162.3
  309 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002162 unedited
  GATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCACCTTCCTCT
  GTCAGAATGGCCACCATGGTACCATCCGTGTTGTGGCCCAGGGCCTGCTGGACTCTGCTG
  GTCTGCTGTCTGCTGACCCCAGGTGTCCAGGGGCAGGAGTTCCTTTTGCGGGTGGAGCCC
  CAGAACCCTGTGCTCTCTGCTGGAGGGTCCCTGTTTGTGAACTGCAGTACTGATTGTCCC
  AGCTCTGAGAAAATCGCCTTGGAGACGTCCCTATCAAAGGAGCTGGTGGCCAGTGGCATG
  GGCTGGGCAGCCTTCAATCTCAGCAACGTGACTGGCAACAGTCGGATCCTCTGCTCAGTG
  TACTGCAATGGCTCCCAGATAACAGGCTCCTCTAACATCACCGTGTACAGGCTCCCGGAG
  CGTGTGGAGCTGGCACCCCTGCCTCCTTGGCAGCCGGTGGGCCAGAACTTCACCCTGCGC
  TGCCAAGTGGAGGATGGGTCGCCCCGGACCAGCCTCACGGTGGTGCTGTTTCGCTGGGAG
  GAGGAGCTGAGCCGGCAGCCCGCAGTGGAGGAGCCAGCGGAGGTCACTGCCACTGTGCTG
  GCCAGCAGAGACGACCACGGAGCCCCTTTCTCATGCCGCACAGAACTGGACATGCAGCCC
  CAGGGGCTGGGACTGTTCGTGACACCCTCAGCCCCCCGCCAGCTCCGAACCTTTGTCCTG
  CCCCGTGACCCCCCGCGCCTCGTGGCCCCCCGGNTCTTGGAGGTGGAAACGTCGTGGCCG
  GTGGACTGCACCCTANACGGGGCTTTCTCGCCTCAGAGCCCAGTTCTACCTGCGCTGNGG
  GACAGATGCTGATGCGACAGTCATGACCCACGGGACACGCTACGGGCCAGNCCAGCCACG
  CGCGCGCGATAAGAGGTGCCCGGAGATCGCTGCACGGACCTAGGGCNAAAACACGGAGCC
  CGGAGACCTGACGTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002162 unedited
  TAGCTTGNNACCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTAGGGAGTT
  TGAAGGCTTTATTGGTGCGGAATCTGAGGGCACAGCCAAGCCCCCGCCAACTTTGATCCC
  GGATCCCAGCGTCACTCAGCTCTGGACGGTTCTTCCCCCATTGCTTCTGTCGGCTGCATA
  GACGTGAGGGGCAGATAGGTGCTCTCCTCCCTAACATGGTAACTGCCGCTCCGTTGGTGC
  TCCCTGAAGACGTACATTAAGGCCAGTACGATAGTCACCACGCCCAGGGTCAGTAACACC
  GCCACGAAGACGGGGACAAAGTGGGAGCTCCCAGCCTCAATGTCCATCACCACGACCAGG
  GTGTATTTGCCTCGTGAGCTGGACGCTTGGCACTGATAAGTACCATTATGTGTTACGTTG
  ACGAAGAACGGGATCCCCACCGGCACCTCCCGGCTGGAGCCTTCCTTCAAACACCGCAGC
  TCGGGGTACGGGTTGCCCCTGGCTTGGCACTGCAGGACGTGTCTCGTTTTATCTTTCCAT
  TTCAAGTGCTGGGGGCATGTGGCTCGGTCAATTTTGGGACCATACAGGACTCGCAGCTGG
  ACGCTACTGTTCCTGTGCAAGAACTCGCCGTCCACCTCGAGAGTGGCACTGCAGAAGAAG
  CTGCGTCCGTCGTCACTCTCGGTAGCATTTAGCTGAAATTGAGCTGGCTGCCCCGGGCCG
  CGGCCGGGACTCCGTCCAGCGTGACCTGGACTCGAGCCCCAGCCATGCAACTCACGGTCA
  CTGTGGACCCCTCATGGGCGGTGGGCTCGCTGAGGTTTCACAATGGTCCTAGGAAACC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002162
• Insert Size: 1900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002162.2, NP_002153.1
• RefSeq Size: 1824 bp
• RefSeq ORF: 1644 bp
• Locus ID: 3385
• Cytogenetics: 19p13.2
• Domains: ig, IG, ICAM_N
• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: 'The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]'
  Transcript Variant: This variant (1) encodes the longest isoform (1).