Nogo A (RTN4) (NM_020532) Human Untagged Clone

CAT#: SC128184

RTN4 (untagged)-Human reticulon 4 (RTN4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RTN4
• Synonyms: ASY; Nbla00271; Nbla10545; NI220/250; NOGO; NSP; NSP-CL; RTN-X; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128184 sequence for NM_020532 edited (data generated by NextGen Sequencing)
  ATGGAAGACCTGGACCAGTCTCCTCTGGTCTCGTCCTCGGACAGCCCACCCCGGCCGCAG
  CCCGCGTTCAAGTACCAGTTCGTGAGGGAGCCCGAGGACGAGGAGGAAGAAGAGGAGGAG
  GAAGAGGAGGACGAGGACGAAGACCTGGAGGAGCTGGAGGTGCTGGAGAGGAAGCCCGCC
  GCCGGGCTGTCCGCGGCCCCAGTGCCCACCGCCCCTGCCGCCGGCGCGCCCCTGATGGAC
  TTCGGAAATGACTTCGTGCCGCCGGCGCCCCGGGGACCCCTGCCGGCCGCTCCCCCCGTC
  GCCCCGGAGCGGCAGCCGTCTTGGGACCCGAGCCCGGTGTCGTCGACCGTGCCCGCGCCA
  TCCCCGCTGTCTGCTGCCGCAGTCTCGCCCTCCAAGCTCCCTGAGGACGACGAGCCTCCG
  GCCCGGCCTCCCCCTCCTCCCCCGGCCAGCGTGAGCCCCCAGGCAGAGCCCGTGTGGACC
  CCGCCAGCCCCGGCTCCCGCCGCGCCCCCCTCCACCCCGGCCGCGCCCAAGCGCAGGGGC
  TCCTCGGGCTCAGTGGATGAGACCCTTTTTGCTCTTCCTGCTGCATCTGAGCCTGTGATA
  CGCTCCTCTGCAGAAAATATGGACTTGAAGGAGCAGCCAGGTAACACTATTTCGGCTGGT
  CAAGAGGATTTCCCATCTGTCCTGCTTGAAACTGCTGCTTCTCTTCCTTCTCTGTCTCCT
  CTCTCAGCCGCTTCTTTCAAAGAACATGAATACCTTGGTAATTTGTCAACAGTATTACCC
  ACTGAAGGAACACTTCAAGAAAATGTCAGTGAAGCTTCTAAAGAGGTCTCAGAGAAGGCA
  AAAACTCTACTCATAGATAGAGATTTAACAGAGTTTTCAGAATTAGAATACTCAGAAATG
  GGATCATCGTTCAGTGTCTCTCCAAAAGCAGAATCTGCCGTAATAGTAGCAAATCCTAGG
  GAAGAAATAATCGTGAAAAATAAAGATGAAGAAGAGAAGTTAGTTAGTAATAACATCCTT
  CATAATCAACAAGAGTTACCTACAGCTCTTACTAAATTGGTTAAAGAGGATGAAGTTGTG
  TCTTCAGAAAAAGCAAAAGACAGTTTTAATGAAAAGAGAGTTGCAGTGGAAGCTCCTATG
  AGGGAGGAATATGCAGACTTCAAACCATTTGAGCGAGTATGGGAAGTGAAAGATAGTAAG
  GAAGATAGTGATATGTTGGCTGCTGGAGGTAAAATCGAGAGCAACTTGGAAAGTAAAGTG
  GATAAAAAATGTTTTGCAGATAGCCTTGAGCAAACTAATCACGAAAAAGATAGTGAGAGT
  AGTAATGATGATACTTCTTTCCCCAGTACGCCAGAAGGTATAAAGGATCGTTCAGGAGCA
  TATATCACATGTGCTCCCTTTAACCCAGCAGCAACTGAGAGCATTGCAACAAACATTTTT
  CCTTTGTTAGGAGATCCTACTTCAGAAAATAAGACCGATGAAAAAAAAATAGAAGAAAAG
  AAGGCCCAAATAGTAACAGAGAAGAATACTAGCACCAAAACATCAAACCCTTTTCTTGTA
  GCAGCACAGGATTCTGAGACAGATTATGTCACAACAGATAATTTAACAAAGGTGACTGAG
  GAAGTCGTGGCAAACATGCCTGAAGGCCTGACTCCAGATTTAGTACAGGAAGCATGTGAA
  AGTGAATTGAATGAAGTTACTGGTACAAAGATTGCTTATGAAACAAAAATGGACTTGGTT
  CAAACATCAGAAGTTATGCAAGAGTCACTCTATCCTGCAGCACAGCTTTGCCCATCATTT
  GAAGAGTCAGAAGCTACTCCTTCACCAGTTTTGCCTGACATTGTTATGGAAGCACCATTG
  AATTCTGCAGTTCCTAGTGCTGGTGCTTCCGTGATACAGCCCAGCTCATCACCATTAGAA
  GCTTCTTCAGTTAATTATGAAAGCATAAAACATGAGCCTGAAAACCCCCCACCATATGAA
  GAGGCCATGAGTGTATCACTAAAAAAAGTATCAGGAATAAAGGAAGAAATTAAAGAGCCT
  GAAAATATTAATGCAGCTCTTCAAGAAACAGAAGCTCCTTATATATCTATTGCATGTGAT
  TTAATTAAAGAAACAAAGCTTTCTGCTGAACCAGCTCCGGATTTCTCTGATTATTCAGAA
  ATGGCAAAAGTTGAACAGCCAGTGCCTGATCATTCTGAGCTAGTTGAAGATTCCTCACCT
  GATTCTGAACCAGTTGACTTATTTAGTGATGATTCAATACCTGACGTTCCACAAAAACAA
  GATGAAACTGTGATGCTTGTGAAAGAAAGTCTCACTGAGACTTCATTTGAGTCAATGATA
  GAATATGAAAATAAGGAAAAACTCAGTGCTTTGCCACCTGAGGGAGGAAAGCCATATTTG
  GAATCTTTTAAGCTCAGTTTAGATAACACAAAAGATACCCTGTTACCTGATGAAGTTTCA
  ACATTGAGCAAAAAGGAGAAAATTCCTTTGCAGATGGAGGAGCTCAGTACTGCAGTTTAT
  TCAAATGATGACTTATTTATTTCTAAGGAAGCACAGATAAGAGAAACTGAAACGTTTTCA
  GATTCATCTCCAATTGAAATTATAGATGAGTTCCCTACATTGATCAGTTCTAAAACTGAT
  TCATTTTCTAAATTAGCCAGGGAATATACTGACCTAGAAGTATCCCACAAAAGTGAAATT
  GCTAATGCCCCGGATGGAGCTGGGTCATTGCCTTGCACAGAATTGCCCCATGACCTTTCT
  TTGAAGAACATACAACCCAAAGTTGAAGAGAAAATCAGTTTCTCAGATGACTTTTCTAAA
  AATGGGTCTGCTACATCAAAGGTGCTCTTATTGCCTCCAGATGTTTCTGCTTTGGCCACT
  CAAGCAGAGATAGAGAGCATAGTTAAACCCAAAGTTCTTGTGAAAGAAGCTGAGAAAAAA
  CTTCCTTCCGATACAGAAAAAGAGGACAGATCACCATCTGCTATATTTTCAGCAGAGCTG
  AGTAAAACTTCAGTTGTTGACCTCCTGTACTGGAGAGACATTAAGAAGACTGGAGTGGTG
  TTTGGTGCCAGCCTATTCCTGCTGCTTTCATTGACAGTATTCAGCATTGTGAGCGTAACA
  GCCTACATTGCCTTGGCCCTGCTCTCTGTGACCATCAGCTTTAGGATATACAAGGGTGTG
  ATCCAAGCTATCCAGAAATCAGATGAAGGCCACCCATTCAGGGCATATCTGGAATCTGAA
  GTTGCTATATCTGAGGAGTTGGTTCAGAAGTACAGTAATTCTGCTCTTGGTCATGTGAAC
  TGCACGATAAAGGAACTCAGGCGCCTCTTCTTAGTTGATGATTTAGTTGATTCTCTGAAG
  TTTGCAGTGTTGATGTGGGTATTTACCTATGTTGGTGCCTTGTTTAATGGTCTGACACTA
  CTGATTTTGGCTCTCATTTCACTCTTCAGTGTTCCTGTTATTTATGAACGGCATCAGGCA
  CAGATAGATCATTATCTAGGACTTGCAAATAAGAATGTTAAAGATGCTATGGCTAAAATC
  CAAGCAAAAATCCCTGGATTGAAGCGCAAAGCTGAATGA
  
  Clone variation with respect to NM_020532.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020532 unedited
  CATATTTTGTAATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGGCGGCGGCAA
  CTGGGGACAGGGCGGGTGGCGCATCACCGGCGCGGAGGCAGGAGGAGCAGTCTCATTGTT
  CCGGGAGCCGTCACCACAGTAGGTCCCTCGGCTCAGTCGGCCCAGCCCCTCTCAGTCCTC
  CCCAACCCCCACAACCGCCCGCGGCTCTGAGACGCGGCCCCGGCGGCGGCGGCAGCAGCT
  GCAGCATCATCTCCACCCTCCAGCCATGGAAGACCTGGACCAGTCTCCTCTGGTCTCGTC
  CTCGGACAGCCCACCCCGGCCGCAGCCCGCGTTCAAGTACCAGTTCGTGAGGGAGCCCGA
  GGACGAGGAGGAAGAAGAGGAGGAGGAAGAGGAGGACGAGGACGAAGACCTGGAGGAGCT
  GGAGGTGCTGGAGAGGAAGCCCGCCGCCGGGCTGTCCGCGGCCCCAGTGCCCACCGCCCC
  TGCCGCCGGCGCGCCCCTGATGGACTTCGGAAATGACTTCGTGCCGCCGGCGCCCCGGGG
  ACCCCTGCCGGCCGCTCCCCCCGTCGCCCCGGAGCGGCAGCCGTCTTGGGACCCGAGCCC
  GGTGTCGTCGACCGTGCCCGCGCCATCCCCGCTGTCTGCTGCCGCAGTCTCGCCCTCCAA
  GCTCCCTGAGGACGACAGCCTCGGCCCGGGNCTNCCCTNTTTNCCCGGGNNNNNGNGAGN
  CCCACTGCNNAGCCCGGGGGGGCCCNGGNCCGCCCCCGGTTCCGGCCGGGCCCCCCNCCC
  CCCCGGGCCGGGCCCNGCGCGGGGGCCCCCTGGGGCCCCGGGGGGGGGACCCTTNNGCCC
  TCTCTGCTGGNTCNGGGCCTGGGTTCGCTCTTTTTCGGNNNTTTGGGCTTTGGGGGCCCC
  CGGTCCCCTTTTCGGTTGGCGGGGGTTTCCCTTGTCTGTTGGNCGGGGGTTTTTTCTTTT
  TGGTCTCTTCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020532 unedited
  TATCTGTGNNACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTCTAGCT
  CCACCATCTCTGCAACTTGCCAAGATGCGGCAAGACTATCTGCAACAAAGTAAAATATAC
  AGGGTTTTTTATTCCACCAGTGCCTCAGATAGATAGGAAAAAGATATGATTACGGTTTAA
  ATCCATACATAGCAGCTTACAATACTTAAGATGATGAACACATGGCAGTCAAGACAGGTA
  ATTTTTCCTCACAACAGTGCATGGCTAAAAATAAAGATCTAACAACGATCTGTGAAACTG
  CACTGCAACGTCAAGGTTCGTTCTTCCCTGACCCTCCCCCGTATAATCAAATGAATATCC
  CCTTTAAAGATGAACTCCTACTAATTATTTTGGGCGTTTTCATTCAGCTTTGCGCTTCAA
  TCCAGGGATTTTTGCTTGGATTTTAGCCATAGCATCTTTAACATTCTTATTTGCAAGTCC
  TAGATAATGATCTATCTGTGCCTGATGCCGTTCATAAATAACAGGAACACTGAAGAGTGA
  AATGAGAGCCAAAATCAGTAGTGTCAGACCATTAAACAAGGCACCAACATAGGTAAATAC
  CCACATCAACACTGCAAACTTCAGAGAATCAACTAAATCATCAACTAAGAAGAGGCGCCT
  GAGTTCCTTTATCGTGCAGTTCACATGACCAAGAGCAGAATTACTGTACTTCTGAACCAA
  CTCCTCAGATATAGCAACTTCAGATTCCAGATATGCCCTGAATGGGTGGCCTTCATCTGA
  TTTCTGGATAGCTTGGATCACACCCTTGTATATCCTAAAGCTGATGGTCACAGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020532
• ORF Size: 3579 bp
• Insert Size: 4500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020532.4, NP_065393.1
• RefSeq Size: 4871
• RefSeq ORF: 3579
• Locus ID: 57142
• Domains: Reticulon
• Protein Families: Transmembrane
• Gene Summary: This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1), also known as Nogo-A and RTN-XL, represents the longest transcript, and encodes the longest isoform (A).