Nogo A (RTN4) (NM_153828) Human Untagged Clone

CAT#: SC128187

RTN4 (untagged)-Human reticulon 4 (RTN4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RTN4
• Synonyms: ASY; Nbla00271; Nbla10545; NI220/250; NOGO; NSP; NSP-CL; RTN-X; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128187 sequence for NM_153828 edited (data generated by NextGen Sequencing)
  ATGGAAGACCTGGACCAGTCTCCTCTGGTCTCGTCCTCGGACAGCCCACCCCGGCCGCAG
  CCCGCGTTCAAGTACCAGTTCGTGAGGGAGCCCGAGGACGAGGAGGAAGAAGAGGAGGAG
  GAAGAGGAGGACGAGGACGAAGACCTGGAGGAGCTGGAGGTGCTGGAGAGGAAGCCCGCC
  GCCGGGCTGTCCGCGGCCCCAGTGCCCACCGCCCCTGCCGCCGGCGCGCCCCTGATGGAC
  TTCGGAAATGACTTCGTGCCGCCGGCGCCCCGGGGACCCCTGCCGGCCGCTCCCCCCGTC
  GCCCCGGAGCGGCAGCCGTCTTGGGACCCGAGCCCGGTGTCGTCGACCGTGCCCGCGCCA
  TCCCCGCTGTCTGCTGCCGCAGTCTCGCCCTCCAAGCTCCCTGAGGACGACGAGCCTCCG
  GCCCGGCCTCCCCCTCCTCCCCCGGCCAGCGTGAGCCCCCAGGCAGAGCCCGTGTGGACC
  CCGCCAGCCCCGGCTCCCGCCGCGCCCCCCTCCACCCCGGCCGCGCCCAAGCGCAGGGGC
  TCCTCGGGCTCAGTGGTTGTTGACCTCCTGTACTGGAGAGACATTAAGAAGACTGGAGTG
  GTGTTTGGTGCCAGCCTATTCCTGCTGCTTTCATTGACAGTATTCAGCATTGTGAGCGTA
  ACAGCCTACATTGCCTTGGCCCTGCTCTCTGTGACCATCAGCTTTAGGATATACAAGGGT
  GTGATCCAAGCTATCCAGAAATCAGATGAAGGCCACCCATTCAGGGCATATCTGGAATCT
  GAAGTTGCTATATCTGAGGAGTTGGTTCAGAAGTACAGTAATTCTGCTCTTGGTCATGTG
  AACTGCACGATAAAGGAACTCAGGCGCCTCTTCTTAGTTGATGATTTAGTTGATTCTCTG
  AAGTTTGCAGTGTTGATGTGGGTATTTACCTATGTTGGTGCCTTGTTTAATGGTCTGACA
  CTACTGATTTTGGCTCTCATTTCACTCTTCAGTGTTCCTGTTATTTATGAACGGCATCAG
  GCACAGATAGATCATTATCTAGGACTTGCAAATAAGAATGTTAAAGATGCTATGGCTAAA
  ATCCAAGCAAAAATCCCTGGATTGAAGCGCAAAGCTGAATGA
  
  Clone variation with respect to NM_153828.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153828 unedited
  TTGGATTTTGTAATACGACTCTCTATTAGGGCGGCCGCGAATTCGCACGAGCCACCCTCC
  AGCCATGGAAGACCTGGACCAGTCTCCTCTGGTCTCGTCCTCGGACAGCCCACCCCGGCC
  GCAGCCCGCGTTCAAGTACCAGTTCGTGAGGGAGCCCGAGGACGAGGAGGAAGAAGAGGA
  GGAGGAAGAGGAGGACGAGGACGAAGACCTGGAGGAGCTGGAGGTGCTGGAGAGGAAGCC
  CGCCGCCGGGCTGTCCGCGGCCCCAGTGCCCACCGCCCCTGCCGCCGGCGCGCCCCTGAT
  GGACTTCGGAAATGACTTCGTGCCGCCGGCGCCCCGGGGACCCCTGCCGGCCGCTCCCCC
  CGTCGCCCCGGAGCGGCAGCCGTCTTGGGACCCGAGCCCGGTGTCGTCGACCGTGCCCGC
  GCCATCCCCGCTGTCTGCTGCCGCAGTCTCGCCCTCCAAGCTCCCTGAGGACGACGAGCC
  TCCGGCCCGGGCCTCCCCCTTCTTCCCCGGNCAGNGNGAGCCCCCNAGCAGAGCCCGNGN
  GGACCCCGCCAGCCCCGGCTTCCGGCGNGCCCCCCNCCACCCCGGCCGCGCCCAAACGCA
  GGGGCNCCCCGGCCCCAGGGGNGGGGGACCCCCCGGACGGGAAAGACACAAAAAGACCGG
  AGGGGCGGCNGGNGCCCACCCAANCCCGCCGCCCACAGGCAGGACCCACGCAGGGGAGCG
  GAACAGCCCACAANGGCCGGGGCCCGGCCCCCGGACCAACAACCCGAAGGAAAACAGGGG
  GGGAACCAAGCGCCCCAAAAAAAAGAGGAGGGCCCCCCACCCGGGGCAAANNGGGACCCC
  GCAACGGCCCAACCCGAAGGGGGGGGCACAAAGACACCAAACCCGGCCCTGGACAAGGGA
  GCCGGCCAAAAAGCAACCCAGGCCCCCCNNCCAACGGCGACCCAACAGACCCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_153828 unedited
  GACTCGGATTTTTTTCTTTTTTTTTTTCTAGCTCCACCATCTCTGCAACTTGCCAANATG
  CGGCAAGACTATCTGCAACAAAGTAAAATATACAGGTTTTTTATTCCACCAGTGCCTCAG
  ATTAGATAGGAAAAAGATATGATTACGGTTTAAATCCATACATAGCAGCTTACAATACTT
  AAGATGATGAACACATGGCAGTCAAGACAGGTAATTTTTCCTCACAACAGTGCATGGCTA
  AAAATAAAGATCTAACAACGATCTGTGAAACTGCACTGCAACGTCAAGGTTCGTTCTTCC
  CTGACCCTCCCCCGTATAATCAAATGAATATCCCCTTTAAAGATGAACTCCTACTAATTA
  TTTTGGGCGTTTTCATTCAGCTTTGCGCTTCAATCCAGGGATTTTTGCTTGGATTTTAGC
  CATAGCATCTTTAACATTCTTATTTGCAAGTCCTAGATAATGATCTATCTGTGCCTGATG
  CCGTTCATAAATAACAGGGACACTGAAGAGTGAAAGGAGAGCCAAAATCAGTGGTGTCAG
  CCCATTAAACAAGGCCCCAACTTAGGGAAATACCCACATTAACCCTGCAAACTTTAGGGA
  ATCAACTTAATCATCCACTAAGAAGAGGCCCCTGGGTTCCTTTTTCGGGGCAGTTACCTG
  ACCCAGGGCGGAATTCCTGTACTTTTGAACCAACTCCTCAGATTTGGAACCTTAGATTCC
  CAGTTTTGCCCTGGAGGGGGGGGCCTTCAACTGGATTCTTGGGAAGGTTGGGACACACCC
  TTTGGTTTTCCAAAAGCTGTTGGGAACAGGAGGCAGGCCCAGGGAATGGTAGGCTGGAAC
  CCCCCCCAAGGTTGAATCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_153828
• ORF Size: 1122 bp
• Insert Size: 1700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_153828.2, NP_722550.1
• RefSeq Size: 2414
• RefSeq ORF: 1122
• Locus ID: 57142
• Protein Families: Transmembrane
• Gene Summary: This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2), also known as Foocen-M, Nogo-B, RTN-XS and RTN4-B1, lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (B), that is missing an internal segment, compared to isoform A.