FYN (NM_153048) Human Untagged Clone

CAT#: SC128257

FYN (untagged)-Human FYN oncogene related to SRC, FGR, YES (FYN), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FYN
• Synonyms: p59-FYN; SLK; SYN
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_153048 edited
  CAGCGCAGGTCTGAGGAGCTGAGAAGGGAGGCTTACGTGAAGGGAATTTAGATAATGGGC
  TGTGTGCAATGTAAGGATAAAGAAGCAACAAAACTGACGGAGGAGAGGGACGGCAGCCTG
  AACCAGAGCTCTGGGTACCGCTATGGCACAGACCCCACCCCTCAGCACTACCCCAGCTTC
  GGTGTGACCTCCATCCCCAACTACAACAACTTCCACGCAGCCGGGGGCCAAGGACTCACC
  GTCTTTGGAGGTGTGAACTCTTCGTCTCATACGGGGACCTTGCGTACGAGAGGAGGAACA
  GGAGTGACACTCTTTGTGGCCCTTTATGACTATGAAGCACGGACAGAAGATGACCTGAGT
  TTTCACAAAGGAGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGGGAAGCC
  CGCTCCTTGACAACTGGAGAGACAGGTTACATTCCCAGCAATTATGTGGCTCCAGTTGAC
  TCTATCCAGGCAGAAGAGTGGTACTTTGGAAAACTTGGCCGAAAAGATGCTGAGCGACAG
  CTATTGTCCTTTGGAAACCCAAGAGGTACCTTTCTTATCCGCGAGAGTGAAACCACCAAA
  GGTGCCTATTCACTTTCTATCCGTGATTGGGATGATATGAAAGGAGACCATGTCAAACAT
  TATAAAATTCGCAAACTTGACAATGGTGGATACTACATTACCACCCGGGCCCAGTTTGAA
  ACACTTCAGCAGCTTGTACAACATTACTCAGGTACCTGGAATGGAAACACAAAAGTAGCC
  ATAAAGACTCTTAAACCAGGCACAATGTCCCCCGAATCATTCCTTGAGGAAGCGCAGATC
  ATGAAGAAGCTGAAGCACGACAAGCTGGTCCAGCTCTATGCAGTGGTGTCTGAGGAGCCC
  ATCTACATCGTCACCGAGTATATGAACAAAGGAAGTTTACTGGATTTCTTAAAAGATGGA
  GAAGGAAGAGCTCTGAAATTACCAAATCTTGTGGACATGGCAGCACAGGTGGCTGCAGGA
  ATGGCTTACATCGAGCGCATGAATTATATCCATAGAGATCTGCGATCAGCAAACATTCTA
  GTGGGGAATGGACTCATATGCAAGATTGCTGACTTCGGATTGGCCCGATTGATAGAAGAC
  AATGAGTACACAGCAAGACAAGGTGCAAAGTTCCCCATCAAGTGGACGGCCCCCGAGGCA
  GCCCTGTACGGGAGGTTCACAATCAAGTCTGACGTGTGGTCTTTTGGAATCTTACTCACA
  GAGCTGGTCACCAAAGGAAGAGTGCCATACCCAGGCATGAACAACCGGGAGGTGCTGGAG
  CAGGTGGAGCGAGGCTACAGGATGCCCTGCCCGCAGGACTGCCCCATCTCTCTGCATGAG
  CTCATGATCCACTGCTGGAAAAAGGACCCTGAAGAACGCCCCACTTTTGAGTACTTGCAG
  AGCTTCCTGGAAGACTACTTTACCGCGACAGAGCCCCAGTACCAACCTGGTGAAAACCTG
  TAAGGCCCGGGTCTGCGGAGAGAGGCCTTGTCCCAGAGGCTGCCCCACCCCTCCCCATTA
  GCTTTCAATTCCGTAGCCAGCTGCTCCCCAGCAGCGGAACCGCCCAGGATCAGATTGCAT
  GTGACTCTGAAGCTGACGAACTTCCATGGCCCTCATTAATGACACTTGTCCCCAAATCCG
  AACCTCCTCTGTGAAGCATTCGAGACAGAACCTTGTTATTTCTCAGACTTTGGAAAATGC
  ATTGTATCGATGTTATGTAAAAGGCCAAACCTCTGTTCAGTGTAAATAGTTACTCCAGTG
  CCAACAATCCTAGTGCTTTCCTTTTTTAAAAATGCAAATCCTATGTGATTTTAACTCTGT
  CTTCACCTGATTCAACTAAAAAAAAAAAAGTATTATTTTCCAAAAGTGGCCTCTTTGTCT
  AAAACAATAAAATTTTTTTTCATGTTTTAACAAAAACCAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153048 unedited
  GGTTCACATTTTGTATACGACTCATATAGGCGGCCGCGNATTCCCGGGNATCAGCGCAGT
  CTGAGGAGCTGAGAAGGAGGCTTACGTGAAGGGAATTTAGATAATGGGCTGTGTGCAATG
  TAAGGATAAAGAAGCAACAAAACTGACGGAGGAGAGGGACGGCAGCCTGAACCAGAGCTC
  TGGGTACCGCTATGGCACAGACCCCACCCCTCAGCACTACCCCAGCTTCGGTGTGACCTC
  CATCCCCAACTACAACAACTTCCACGCAGCCGGGGGCCAAGGACTCACCGTCTTTGGAGG
  TGTGAACTCTTCGTCTCATACGGGGACCTTGCGTACGAGAGGAGGAACAGGAGTGACACT
  CTTTGTGGCCCTTTATGACTATGAAGCACGGACAGAAGATGACCTGAGTTTTCACAAAGG
  AGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGGGAAGCCCGCTCCTTGAC
  AACTGGAGAGACAGGTTACATTCCCAGCAATTATGTGGCTCCAGTTGACTCTATCCAGGC
  AGAAGAGTGGTACTTTGGAAAACTTGGCCGANAAGATGCTGAGCGACAGCTATTGTCCTT
  TGGAAACCCAAGAGGTACCTTTCTTATCCGCGAGAGTGAAACCACCAAAGGTGCCTATTC
  ACTTTCTATCCGTGATTGGGATGATATGAAAGGAGACCATGTCAAACATTATAAAATTCG
  CAAACTTGACAATGGTGGATACTACATTACCACCCGGNCCCAGTTTTGAACACTTCAGCA
  GCTTGTACAACATTACTCANGTACCTGNAATGGAAACACAAAGTAGCCATAAAGACTCTT
  AAACANGCACAATGTTCCCCCGAATCATTCCTTTGAGAAGCGCANATCATGNAGAAGCTG
  AAGCCACGACAGCTGG
  
• Restriction Sites: Please inquire
• ACCN: NM_153048
• Insert Size: 2000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_153048.1, NP_694593.1
• RefSeq Size: 2000 bp
• RefSeq ORF: 1449 bp
• Locus ID: 2534
• Cytogenetics: 6q21
• Domains: pkinase, SH2, TyrKc, SH3, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Adherens junction, Axon guidance, Fc epsilon RI signaling pathway, Focal adhesion, Natural killer cell mediated cytotoxicity, Pathogenic Escherichia coli infection, Prion diseases, T cell receptor signaling pathway, Viral myocarditis
• Gene Summary: 'This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (3) differs in the 5' UTR, and lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (c) that is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.