LHCGR (NM_000233) Human Untagged Clone

CAT#: SC300031

LHCGR (untagged)-Human luteinizing hormone/choriogonadotropin receptor (LHCGR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LHCGR
• Synonyms: HHG; LCGR; LGR2; LH/CG-R; LH/CGR; LHR; LHRHR; LSH-R; ULG5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000233, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCAGCGGTTCTCGGCGCTGCAGCTGCTGAAGCTGCTGCTGCTGCTGCAGCCGCCGCTGCCACGAG
  CGCTGCGCGAGGCGCTCTGCCCTGAGCCCTGCAACTGCGTGCCCGACGGCGCCCTGCGCTGCCCCGGCCC
  CACGGCCGGTCTCACTCGACTATCACTTGCCTACCTCCCTGTCAAAGTGATCCCATCTCAAGCTTTCAGA
  GGACTTAATGAGGTCATAAAAATTGAAATCTCTCAGATTGATTCCCTGGAAAGGATAGAAGCTAATGCCT
  TTGACAACCTCCTCAATTTGTCTGAAATACTGATCCAGAACACCAAAAATCTGAGATACATTGAGCCCGG
  AGCATTTATAAATCTTCCCCGATTAAAATACTTGAGCATCTGTAACACAGGCATCAGAAAGTTTCCAGAT
  GTTACGAAGGTCTTCTCCTCTGAATCAAATTTCATTCTGGAAATTTGTGATAACTTACACATAACCACCA
  TACCAGGAAATGCTTTTCAAGGGATGAATAATGAATCTGTAACACTCAAACTATATGGAAATGGATTTGA
  AGAAGTACAAAGTCATGCATTCAATGGGACGACACTGACTTCACTGGAGCTAAAGGAAAACGTACATCTG
  GAGAAGATGCACAATGGAGCCTTCCGTGGGGCCACAGGGCCGAAAACCTTGGATATTTCTTCCACCAAAT
  TGCAGGCCCTGCCGAGCTATGGCCTAGAGTCCATTCAGAGGCTAATTGCCACGTCATCCTATTCTCTAAA
  AAAATTGCCATCAAGAGAAACATTTGTCAATCTCCTGGAGGCCACGTTGACTTACCCCAGCCACTGCTGT
  GCTTTTAGAAACTTGCCAACAAAAGAACAGAATTTTTCACATTCCATTTCTGAAAACTTTTCCAAACAAT
  GTGAAAGCACAGTAAGGAAAGTGAATAACAAAACACTTTATTCTTCCATGCTTGCTGAGAGTGAACTGAG
  TGGCTGGGACTATGAATATGGTTTCTGCTTACCCAAGACACCCCGATGTGCTCCTGAACCAGATGCTTTT
  AATCCCTGTGAAGATATTATGGGCTATGACTTCCTTAGGGTCCTGATTTGGCTGATTAATATTCTAGCCA
  TCATGGGAAACATGACTGTTCTTTTTGTTCTCCTGACAAGTCGTTACAAACTTACAGTGCCTCGTTTTCT
  CATGTGCAATCTCTCCTTTGCAGACTTTTGCATGGGGCTCTATCTGCTGCTCATAGCCTCAGTTGATTCC
  CAAACCAAGGGCCAGTACTATAACCATGCCATAGACTGGCAGACAGGGAGTGGGTGCAGCACTGCTGGCT
  TTTTCACTGTATTCGCAAGTGAACTTTCTGTCTACACCCTCACCGTCATCACTCTAGAAAGATGGCACAC
  CATCACCTATGCTATTCACCTGGACCAAAAGCTGCGATTAAGACATGCCATTCTGATTATGCTTGGAGGA
  TGGCTCTTTTCTTCTCTAATTGCTATGTTGCCCCTTGTCGGTGTCAGCAATTACATGAAGGTCAGTATTT
  GCTTCCCCATGGATGTGGAAACCACTCTCTCACAAGTCTATATATTAACCATCCTGATTCTCAATGTGGT
  GGCCTTCTTCATAATTTGTGCTTGCTACATTAAAATTTATTTTGCAGTTCGAAACCCAGAATTAATGGCT
  ACCAATAAAGATACAAAGATTGCTAAGAAAATGGCAATCCTCATCTTCACCGATTTCACCTGCATGGCAC
  CTATCTCTTTTTTTGCCATCTCAGCTGCCTTCAAAGTACCTCTTATCACAGTAACCAACTCTAAAGTTTT
  ACTGGTTCTTTTTTATCCCATCAATTCTTGTGCCAATCCATTTCTGTATGCAATATTCACTAAGACATTC
  CAAAGAGATTTCTTTCTTTTGCTGAGCAAATTTGGCTGCTGTAAACGTCGGGCTGAACTTTATAGAAGGA
  AAGATTTTTCAGCTTACACCTCCAACTGCAAAAATGGCTTCACTGGATCAAATAAGCCTTCTCAATCCAC
  CTTGAAGTTGTCCACATTGCACTGTCAAGGTACAGCTCTCCTAGACAAGACTCGCTACACAGAGTGTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_000233
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000233.3, NP_000224.2
• RefSeq Size: 3093 bp
• RefSeq ORF: 2100 bp
• Locus ID: 3973
• Cytogenetics: 2p16.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: 'This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]'