Plectin (PLEC) (NM_000445) Human Untagged Clone

CAT#: SC300071

PLEC (untagged)-Human plectin (PLEC), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLEC
• Synonyms: EBS1; EBSMD; EBSND; EBSO; EBSOG; EBSPA; HD1; LGMD2Q; LGMDR17; PCN; PLEC1; PLEC1b; PLTN
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000445, the custom clone sequence may differ by one or more nucleotides
  ATGTCGGGTGAGGACGCTGAGGTCCGGGCAGTCTCTGAAGATGTCTCCAATGGAAGCAGT
  GGCTCGCCCAGCCCTGGGGACACACTGCCCTGGAACCTTGGGAAAACGCAGCGGAGCCGG
  CGCAGCGGGGGTGGCGCTGGGAGCAACGGGAGTGTCCTGGACCCAGCTGAGCGGGCGGTC
  ATTCGCATCGCAGATGAGCGGGATCGTGTGCAGAAGAAAACCTTCACCAAGTGGGTCAAC
  AAGCACCTCATCAAGGCCCAGAGGCACATCAGTGACCTGTATGAAGACCTCCGCGATGGC
  CACAACCTCATCTCCCTGCTGGAGGTCCTCTCGGGGGACAGCCTGCCCCGGGAGAAGGGG
  AGGATGCGTTTCCACAAGCTGCAGAATGTCCAGATTGCCCTGGACTACCTCCGGCACCGC
  CAGGTGAAGCTGGTGAACATCAGGAATGATGACATCGCTGACGGCAACCCCAAGCTGACC
  CTTGGCCTCATCTGGACAATCATTCTGCACTTCCAGATCTCAGATATCCAGGTGAGTGGG
  CAGTCGGAGGACATGACGGCCAAGGAGAAGCTGCTGCTGTGGTCGCAGCGAATGGTGGAG
  GGGTACCAGGGCCTGCGATGCGACAACTTCACCTCCAGCTGGAGAGACGGCCGCCTCTTC
  AATGCCATCATCCACCGGCACAAGCCCCTGCTCATCGACATGAACAAGGTGTACCGGCAG
  ACCAACCTGGAGAACCTGGACCAGGCCTTCTCTGTGGCGGAGCGGGACCTGGGAGTGACG
  CGGCTCCTGGACCCTGAGGACGTGGATGTCCCTCAGCCCGACGAGAAGTCCATCATCACC
  TACGTCTCGTCGCTGTATGACGCCATGCCCCGCGTGCCGGACGTGCAGGATGGGGTGAGG
  GCCAACGAGCTGCAGCTGCGCTGGCAGGAGTACCGGGAGCTGGTGCTGCTGCTGCTTCAG
  TGGATGCGACACCACACGGCCGCCTTTGAGGAACGCAGGTTCCCCTCCAGCTTCGAGGAG
  ATTGAGATCCTGTGGTCTCAGTTCCTGAAGTTTAAGGAGATGGAGCTACCAGCCAAGGAG
  GCCGACAAGAACAGGTCCAAGGGCATCTACCAATCCCTGGAGGGAGCGGTGCAAGCAGGC
  CAGCTCAAGGTGCCCCCTGGCTACCACCCGCTGGATGTGGAGAAGGAGTGGGGCAAGCTG
  CACGTGGCCATCCTGGAGCGGGAGAAGCAGCTCCGCAGCGAGTTTGAGAGGCTGGAGTGT
  CTTCAGCGCATCGTGACCAAGCTGCAGATGGAGGCGGGGCTGTGTGAGGAGCAGCTGAAC
  CAGGCCGACGCCCTGCTGCAGTCGGATGTCCGGCTGCTGGCTGCAGGCAAAGTGCCACAG
  CGGGCGGGGGAGGTGGAACGGGACTTGGACAAGGCGGATAGCATGATCCGGCTGCTCTTC
  AACGACGTGCAGACCCTCAAGGATGGACGGCACCCGCAGGGCGAGCAGATGTACCGCAGG
  GTGTACCGTCTGCACGAGCGCCTGGTAGCCATCCGCACCGAGTACAACCTACGGCTGAAG
  GCAGGCGTGGCGGCCCCTGCAACCCAGGTGGCCCAGGTGACTCTGCAGAGTGTGCAGAGG
  CGCCCCGAGCTGGAGGACTCCACTCTGCGCTACCTGCAGGACCTGCTGGCCTGGGTGGAG
  GAGAACCAGCACCGTGTGGATGGCGCTGAGTGGGGTGTGGACCTGCCCAGCGTGGAGGCG
  CAGCTGGGCAGCCACCGAGGCCTGCACCAGTCCATCGAAGAATTCCGGGCCAAGATCGAG
  CGGGCACGGAGTGACGAGGGCCAGCTCTCCCCCGCCACCCGGGGTGCCTACCGTGACTGC
  CTGGGTCGGCTGGACCTGCAGTACGCCAAGCTGCTGAACTCCTCCAAGGCCCGCCTCAGG
  TCCCTGGAGAGCTTGCACAGCTTTGTGGCAGCCGCCACTAAGGAGCTAATGTGGCTGAAT
  GAGAAGGAGGAGGAGGAGGTGGGCTTCGACTGGAGCGACCGCAACACCAACATGACCGCC
  AAGAAGGAGAGCTACTCGGCGCTGATGCGGGAGCTGGAGCTGAAGGAGAAGAAGATCAAG
  GAGCTCCAAAATGCTGGGGACCGGCTGCTGCGGGAGGACCACCCGGCCCGGCCCACGGTG
  GAGTCCTTCCAGGCGGCCCTGCAGACGCAGTGGAGCTGGATGCTACAGCTGTGCTGCTGT
  ATCGAGGCACACCTGAAGGAGAACGCTGCCTACTTTCAGTTCTTCTCAGATGTGCGGGAG
  GCCGAGGGGCAGTTGCAGAAGCTGCAGGAGGCACTGCGTAGGAAATACAGTTGTGATCGC
  TCCGCCACCGTCACCCGGCTGGAGGACCTGCTGCAGGATGCCCAGGACGAGAAGGAACAG
  CTGAACGAGTACAAGGGCCACCTCTCAGGCCTGGCCAAGCGGGCCAAGGCCGTCGTGCAG
  CTGAAGCCCCGCCACCCAGCCCACCCCATGCGGGGCCGCCTGCCCCTGCTGGCCGTGTGC
  GACTATAAGCAGGTGGAGGTGACTGTGCACAAGGGTGACGAGTGCCAGCTGGTGGGCCCT
  GCACAGCCGTCCCACTGGAAGGTGCTCAGCAGCTCCGGCAGCGAGGCCGCCGTGCCCTCC
  GTGTGCTTCCTGGTGCCCCCGCCCAACCAGGAGGCCCAGGAGGCCGTCACCAGGCTGGAG
  GCCCAGCACCAGGCCCTGGTCACGCTGTGGCACCAGTTGCACGTGGACATGAAGAGCCTT
  CTGGCCTGGCAGAGCCTTCGCCGCGACGTGCAGCTCATCCGCTCCTGGTCCCTGGCCACG
  TTCCGCACCCTGAAGCCAGAGGAGCAGCGCCAAGCCCTGCACAGCCTGGAGCTGCACTAC
  CAGGCCTTCCTGCGGGACAGCCAGGACGCGGGCGGCTTCGGACCCGAGGACCGGCTGATG
  GCTGAGCGCGAGTACGGCTCCTGCAGCCACCACTACCAGCAGCTGCTGCAGAGCCTGGAA
  CAGGGTGCACAGGAAGAGTCTCGCTGCCAGCGCTGCATCTCCGAGCTCAAAGACATCCGG
  CTGCAGCTGGAGGCCTGTGAGACGCGCACCGTGCACCGCCTGCGGCTGCCGCTGGACAAA
  GAGCCGGCACGGGAGTGTGCCCAGCGCATCGCCGAGCAGCAGAAGGCACAGGCAGAGGTG
  GAGGGGCTGGGCAAGGGGGTCGCCCGGCTCTCTGCCGAGGCCGAGAAGGTCTTGGCCCTA
  CCAGAGCCATCGCCTGCGGCCCCCACGCTGCGCTCGGAGCTGGAGCTGACGCTGGGCAAG
  CTGGAGCAGGTCCGCAGCCTGTCTGCCATCTACCTGGAGAAGCTCAAGACCATCAGCCTG
  GTGATCCGCGGCACGCAGGGGGCCGAGGAGGTGCTCAGGGCCCACGAGGAGCAGCTCAAG
  GAGGCCCAGGCCGTGCCGGCCACCCTCCCGGAGCTCGAGGCCACCAAGGCCTCTCTGAAG
  AAGCTGCGGGCCCAGGCCGAGGCACAGCAGCCCACGTTCGACGCCCTGCGGGATGAGCTG
  CGGGGGGCACAGGAGGTGGGGGAGCGACTGCAGCAGCGGCACGGGGAGCGGGACGTGGAG
  GTGGAGCGCTGGCGGGAGCGGGTCGCCCAGTTGCTTGAGCGCTGGCAGGCTGTGCTGGCC
  CAGACCGACGTGCGGCAGCGCGAGCTCGAGCAACTGGGCCGCCAGCTGCGTTACTACCGC
  GAGAGTGCAGACCCCTTGGGCGCCTGGCTGCAGGACGCCAGGCGGCGGCAGGAGCAGATC
  CAGGCCATGCCGCTGGCCGACAGCCAGGCTGTGCGGGAGCAGCTGCGGCAGGAGCAGGCC
  CTGCTGGAGGAGATCGAGCGCCACGGCGAGAAGGTCGAGGAGTGCCAGAGGTTTGCGAAA
  CAGTACATCAACGCCATCAAGGACTATGAACTCCAGCTGGTGACGTACAAGGCGCAGCTT
  GAGCCGGTGGCCTCCCCGGCCAAGAAGCCCAAGGTCCAGTCGGGATCAGAGAGTGTCATC
  CAGGAGTACGTGGACCTGCGTACGCACTACAGCGAGCTGACCACACTGACGAGCCAGTAC
  ATCAAGTTCATCAGCGAGACTCTGCGGCGCATGGAGGAGGAGGAGAGGCTGGCTGAGCAG
  CAGCGGGCAGAGGAGCGCGAGCGGCTGGCCGAGGTGGAGGCCGCGCTGGAGAAGCAGCGG
  CAGCTGGCCGAGGCGCACGCCCAGGCAAAGGCACAGGCGGAGCGGGAGGCGAAGGAGCTG
  CAGCAGCGCATGCAGGAGGAGGTGGTGCGGCGGGAGGAGGCGGCGGTGGACGCGCAGCAG
  CAGAAGCGCAGCATTCAGGAGGAGCTGCAGCAGCTGCGGCAGAGCTCGGAGGCGGAGATC
  CAGGCCAAGGCCCGGCAGGCAGAGGCGGCTGAGCGCAGCCGGCTGCGCATCGAGGAGGAG
  ATCCGCGTGGTGCGCCTGCAGTTGGAGGCCACCGAGCGCCAGCGTGGCGGGGCTGAGGGG
  GAGCTGCAGGCACTGCGTGCACGGGCGGAGGAGGCTGAGGCACAAAAGCGACAGGCGCAG
  GAGGAGGCCGAGCGCTTGCGGAGGCAGGTGCAGGACGAGAGCCAGCGTAAGCGGCAGGCG
  GAGGTGGAGCTGGCCTCGCGCGTGAAGGCCGAGGCCGAGGCGGCGCGCGAGAAGCAGCGG
  GCCCTGCAGGCCCTGGAGGAGCTGCGGCTGCAGGCGGAGGAGGCGGAGCGGCGCCTGCGG
  CAGGCCGAGGTGGAGCGAGCGCGGCAGGTACAGGTGGCCCTGGAGACGGCGCAGCGCAGT
  GCAGAGGCGGAGCTGCAGAGCAAACGCGCCTCCTTCGCCGAGAAGACGGCACAGCTGGAG
  CGCTCCCTGCAGGAGGAACACGTGGCTGTGGCACAGCTGCGGGAGGAGGCTGAGCGGCGG
  GCACAGCAGCAGGCCGAGGCCGAGCGGGCGCGCGAGGAGGCAGAGCGGGAGCTGGAGCGC
  TGGCAGCTCAAGGCCAACGAGGCGCTACGGCTGCGGCTGCAGGCGGAGGAGGTGGCGCAG
  CAGAAGAGCCTGGCGCAGGCCGAGGCTGAGAAGCAGAAGGAGGAGGCGGAGCGCGAGGCG
  CGGCGGCGCGGCAAGGCGGAGGAGCAGGCCGTCCGGCAGCGGGAGCTGGCTGAACAAGAG
  CTGGAGAAGCAGCGGCAGCTGGCGGAAGGCACCGCGCAGCAGCGCCTGGCCGCGGAGCAG
  GAGTTGATCCGGCTGCGGGCCGAGACGGAGCAGGGGGAGCAGCAGCGGCAGCTGCTGGAG
  GAGGAGCTGGCCCGGCTGCAGCGTGAGGCGGCTGCAGCCACGCAGAAACGGCAGGAGCTG
  GAAGCCGAGCTGGCCAAGGTGCGGGCCGAGATGGAGGTGCTGCTGGCCAGCAAGGCGAGG
  GCTGAGGAGGAGTCGCGCTCCACCAGCGAGAAGTCCAAGCAGAGGCTGGAGGCCGAGGCC
  GGCCGGTTCCGCGAGCTGGCCGAGGAGGCCGCCCGCCTGCGTGCCCTGGCGGAAGAGGCC
  AAGCGGCAGCGGCAGCTGGCCGAGGAAGACGCGGCGCGGCAGCGGGCCGAGGCGGAGCGG
  GTGCTTGCGGAGAAGCTGGCCGCCATCGGCGAGGCCACGCGGCTCAAGACGGAGGCGGAG
  ATCGCGCTCAAGGAGAAGGAGGCGGAGAACGAGCGCCTGCGGCGGCTGGCGGAGGACGAG
  GCCTTCCAGCGGCGGCGGCTGGAGGAGCAGGCCGCGCAACACAAGGCTGACATCGAGGAG
  CGCCTGGCCCAGCTGCGCAAGGCATCGGACAGCGAGCTGGAGCGGCAGAAGGGGCTGGTG
  GAGGACACGCTGAGGCAGCGGCGGCAGGTGGAGGAGGAGATCCTGGCGCTGAAGGCGAGC
  TTCGAGAAGGCGGCCGCTGGCAAGGCGGAGCTGGAGCTGGAGCTGGGACGCATCCGCAGC
  AACGCGGAGGACACGCTGCGCAGCAAGGAGCAGGCCGAGCTGGAGGCTGCGAGGCAGCGG
  CAGCTGGCGGCGGAGGAGGAGCGGCGGCGCCGTGAGGCTGAGGAGCGCGTGCAGAAGAGC
  CTGGCGGCCGAGGAGGAGGCCGCACGGCAGCGGAAGGCGGCGCTGGAGGAAGTCGAGCGG
  CTGAAAGCCAAGGTGGAGGAGGCGCGGCGCCTGCGGGAGCGAGCGGAGCAGGAGTCGGCG
  CGGCAGCTGCAGCTGGCCCAGGAGGCCGCCCAGAAGCGGCTGCAGGCGGAAGAGAAGGCA
  CACGCCTTCGCGGTGCAGCAGAAGGAGCAGGAGCTACAGCAGACGCTGCAGCAGGAGCAG
  AGCGTGCTGGACCAGCTGCGCGGCGAGGCGGAGGCGGCCCGGCGGGCGGCTGAGGAGGCG
  GAGGAGGCCCGGGTGCAGGCGGAGCGTGAGGCGGCGCAGTCCCGGCGGCAGGTGGAAGAG
  GCCGAGCGGCTGAAGCAGTCGGCAGAGGAGCAGGCACAGGCCCGGGCTCAGGCACAGGCG
  GCTGCAGAGAAGCTGCGCAAGGAGGCCGAGCAAGAGGCGGCGCGGCGGGCACAGGCGGAG
  CAGGCGGCCCTGCGGCAGAAGCAGGCAGCTGACGCGGAGATGGAGAAGCATAAGAAATTC
  GCCGAGCAGACGCTGCGGCAGAAGGCGCAGGTGGAGCAGGAGCTGACAACACTGCGGCTG
  CAGCTGGAGGAGACCGACCACCAGAAGAACCTGCTGGACGAGGAGCTGCAGCGGCTGAAG
  GCGGAGGCCACGGAGGCCGCACGCCAGCGCAGCCAGGTGGAGGAGGAGCTCTTCTCGGTG
  CGCGTGCAGATGGAGGAGCTGAGCAAGCTCAAGGCACGCATCGAGGCTGAGAACCGCGCA
  CTCATCTTGCGTGACAAGGACAATACGCAGCGCTTCCTGCAGGAGGAGGCTGAGAAGATG
  AAGCAGGTGGCGGAGGAGGCCGCGCGGCTGAGTGTGGCGGCCCAAGAGGCTGCGCGACTG
  CGGCAGCTGGCAGAGGAGGACCTGGCACAGCAGCGGGCCTTGGCAGAGAAGATGCTCAAG
  GAGAAGATGCAGGCGGTGCAGGAGGCCACGCGACTCAAGGCTGAGGCGGAACTGCTGCAG
  CAGCAGAAGGAGCTTGCGCAGGAGCAGGCGCGGCGGCTGCAGGAGGACAAGGAGCAGATG
  GCGCAGCAGCTGGCGGAGGAGACGCAGGGCTTCCAGCGGACGCTGGAGGCCGAGCGGCAG
  CGGCAGCTGGAGATGAGCGCTGAGGCTGAGCGCCTCAAGCTGCGTGTGGCCGAGATGAGC
  CGAGCCCAGGCCCGCGCTGAGGAGGACGCCCAGCGCTTCCGGAAGCAGGCGGAGGAGATC
  GGTGAGAAGCTGCACCGCACGGAGCTCGCCACCCAGGAGAAGGTGACCCTGGTGCAGACA
  CTGGAGATCCAGCGACAGCAGAGTGACCATGATGCCGAGCGCCTGCGGGAGGCCATCGCT
  GAGCTGGAGCGTGAGAAGGAGAAGCTCCAACAGGAGGCCAAACTGCTGCAGCTCAAGTCT
  GAGGAGATGCAGACGGTGCAGCAGGAGCAGCTGCTGCAGGAGACGCAGGCCCTGCAGCAA
  AGCTTCCTCTCTGAAAAGGACAGCCTGCTACAGCGGGAGCGCTTCATCGAGCAGGAGAAG
  GCCAAGCTGGAGCAGCTCTTCCAGGACGAGGTGGCCAAGGCACAGCAGCTGCGTGAGGAG
  CAGCAGCGGCAGCAGCAGCAGATGGAGCAGGAACGGCAGCGGCTGGTGGCCAGCATGGAG
  GAGGCGCGGCGGCGGCAGCATGAGGCCGAGGAGGGCGTGCGGCGCAAGCAGGAGGAGCTG
  CAGCAGCTGGAGCAGCAGCGGCGGCAGCAGGAGGAGCTGCTGGCTGAGGAGAACCAGAGG
  CTGCGTGAGCAGCTGCAGCTCCTGGAGGAGCAGCACCGGGCCGCGCTGGCGCACTCAGAG
  GAGGTCACTGCCTCGCAGGTGGCTGCCACAAAGACCCTGCCCAATGGCCGGGATGCACTT
  GATGGCCCCGCGGCAGAGGCAGAGCCGGAGCACAGCTTCGATGGCCTGCGGCGGAAGGTG
  TCAGCTCAGAGGCTGCAGGAGGCCGGCATCCTGAGTGCGGAGGAGCTGCAGCGGTTGGCG
  CAGGGCCACACCACGGTGGACGAGCTCGCACGGCGGGAAGACGTGCGCCACTACCTGCAG
  GGCCGCAGCAGTATCGCAGGGCTGTTGCTGAAGGCCACCAATGAGAAGCTGAGTGTTTAC
  GCCGCCCTGCAGAGGCAGCTGCTGAGTCCCGGCACGGCCCTCATCCTGCTGGAGGCGCAG
  GCGGCCTCAGGCTTCCTGCTGGACCCTGTGCGGAACCGGCGGCTGACCGTCAACGAGGCT
  GTGAAGGAGGGTGTGGTGGGCCCCGAGCTGCACCACAAGCTGCTGTCGGCCGAGCGCGCC
  GTCACTGGCTACAAGGACCCCTACACTGGCCAGCAGATCTCTCTCTTCCAAGCCATGCAG
  AAGGGCCTCATCGTCCGGGAGCACGGCATCCGCCTGCTGGAGGCCCAGATCGCCACGGGC
  GGCGTTATCGACCCCGTGCACAGCCACCGCGTGCCCGTGGACGTGGCCTACCGGCGCGGC
  TACTTCGACGAGGAGATGAACCGCGTCCTGGCGGACCCCAGCGACGACACCAAGGGCTTC
  TTTGACCCCAACACGCACGAGAACCTCACGTACCTGCAGCTACTGGAGCGCTGCGTGGAG
  GACCCCGAGACGGGCCTGTGCCTTCTGCCACTCACGGATAAGGCTGCCAAGGGCGGGGAG
  CTGGTCTACACTGACTCCGAGGCCCGGGACGTCTTTGAGAAGGCCACCGTGTCTGCGCCG
  TTCGGCAAGTTCCAGGGCAAGACGGTGACCATTTGGGAGATCATCAACTCGGAATACTTC
  ACGGCAGAGCAGCGGCGGGACCTGCTGCGGCAGTTCCGCACGGGCCGGATCACAGTGGAG
  AAGATCATCAAGATCATCATCACGGTGGTGGAGGAGCAGGAGCAGAAGGGCCGGCTTTGC
  TTTGAGGGCCTGCGCAGCCTGGTGCCAGCCGCCGAGCTGCTGGAGAGCAGGGTCATCGAC
  CGCGAGCTCTACCAGCAGCTGCAGCGAGGTGAGCGCTCTGTGCGAGACGTAGCCGAGGTG
  GACACTGTGCGGCGGGCTCTCCGGGGTGCCAACGTCATCGCGGGTGTATGGCTGGAGGAG
  GCGGGGCAGAAGCTGAGTATCTACAATGCCCTGAAGAAAGACCTGCTGCCATCCGACATG
  GCCGTGGCCCTGTTGGAAGCCCAGGCCGGCACCGGGCACATCATCGACCCCGCCACCAGC
  GCCCGGCTGACCGTGGACGAGGCAGTGCGTGCTGGCCTGGTGGGCCCCGAGTTTCATGAG
  AAGCTGCTATCAGCCGAGAAGGCTGTGACAGGGTACAGGGACCCCTACACAGGGCAGAGC
  GTCTCCCTGTTCCAGGCCCTGAAGAAGGGCCTCATTCCCCGGGAGCAGGGCCTGCGCCTG
  TTGGACGCCCAGCTGTCCACGGGCGGCATCGTGGACCCCAGCAAGAGCCACCGCGTGCCC
  CTGGATGTCGCCTGCGCCCGAGGCTGCCTGGATGAGGAGACCAGCAGGGCCCTGTCGGCA
  CCAAGGGCCGACGCCAAGGCCTACAGTGACCCCAGCACAGGGGAGCCGGCCACCTACGGC
  GAGCTCCAGCAGCGGTGCCGGCCCGACCAGCTGACCGGGCTGAGCCTGCTGCCGCTCTCA
  GAAAAGGCTGCTCGGGCCCGGCAGGAGGAGCTCTACTCAGAGCTGCAGGCCCGTGAGACC
  TTTGAAAAGACCCCGGTTGAGGTCCCCGTGGGTGGCTTCAAGGGCAGGACGGTGACGGTG
  TGGGAGCTCATCAGCTCTGAGTACTTCACTGCGGAGCAGCGGCAGGAGCTGTTGCGTCAG
  TTCCGCACGGGCAAGGTCACCGTGGAGAAGGTCATCAAGATTCTCATTACCATCGTGGAG
  GAGGTGGAGACCCTGCGGCAGGAGAGGCTGTCCTTCAGCGGCCTCCGTGCCCCTGTGCCA
  GCCAGCGAGCTCCTGGCTTCCGGGGTCCTCAGCAGAGCCCAGTTTGAGCAGCTCAAGGAC
  GGCAAGACGACGGTCAAGGACCTTTCGGAGCTGGGCTCCGTGCGGACGCTGCTGCAGGGC
  AGTGGCTGCCTCGCCGGCATCTACCTGGAGGACACCAAGGAGAAGGTGTCCATCTACGAG
  GCCATGCGCCGGGGCCTGCTGAGAGCCACAACGGCTGCGCTCCTGCTGGAGGCGCAGGCG
  GCCACTGGCTTCCTGGTGGACCCCGTGCGGAACCAGCGCCTGTATGTCCACGAGGCCGTG
  AAGGCGGGCGTGGTGGGCCCCGAGCTTCACGAGCAGCTGCTGTCTGCCGAGAAGGCCGTC
  ACCGGCTACAGAGACCCCTACTCGGGCAGCACCATCTCCCTCTTCCAGGCCATGCAGAAG
  GGCCTGGTTCTCCGGCAGCACGGCATCCGCCTGCTGGAGGCCCAGATCGCCACGGGCGGC
  ATCATCGACCCCGTGCACAGCCACCGCGTGCCTGTGGACGTGGCCTACCAGCGCGGCTAC
  TTCAGTGAGGAGATGAACCGCGTCCTGGCGGACCCCAGCGACGACACCAAGGGCTTCTTT
  GACCCCAACACGCATGAGAACCTCACGTACAGGCAGCTGCTGGAGCGGTGCGTGGAGGAC
  CCCGAGACGGGCTTGCGCCTTCTGCCACTGAAAGGGGCGGAGAAGGCTGAGGTGGTGGAG
  ACCACGCAGGTGTACACTGAGGAGGAGACAAGAAGGGCATTTGAAGAGACACAGATCGAC
  ATTCCCGGCGGCGGCAGCCACGGCGGCTCCACCATGTCCCTGTGGGAGGTGATGCAGTCG
  GACCTGATCCCCGAGGAGCAGCGGGCCCAGCTGATGGCTGACTTCCAGGCCGGCCGGGTG
  ACCAAGGAACGCATGATCATCATCATCATCGAGATCATTGAGAAGACAGAGATCATCCGC
  CAGCAGGGTCTGGCCTCCTACGACTACGTGCGCCGCCGCCTCACGGCTGAGGACCTGTTC
  GAGGCTCGGATCATCTCTCTCGAGACCTACAACCTGCTCCGGGAGGGCACCAGGAGCCTC
  CGTGAGGCTCTCGAGGCGGAGTCCGCCTGGTGCTACCTCTATGGCACGGGCTCCGTGGCT
  GGTGTCTACCTGCCCGGTTCCAGGCAGACACTGAGCATCTACCAGGCTCTCAAGAAAGGG
  CTGCTGAGTGCCGAGGTGGCCCGCCTGCTGCTGGAGGCACAGGCAGCCACAGGCTTCCTG
  CTGGACCCGGTGAAGGGGGAGCGGCTGACTGTGGATGAGGCTGTGCGGAAGGGCCTCGTG
  GGGCCCGAGCTGCACGACCGCCTGCTCTCGGCTGAGCGGGCGGTCACCGGCTACCGTGAC
  CCCTACACCGAGCAGACCATCTCGCTCTTCCAGGCCATGAAGAAGGAGCTGATCCCTACT
  GAGGAGGCCCTGCGGCTGCTGGATGCCCAGCTGGCCACCGGCGGCATCGTGGACCCCCGC
  CTGGGCTTCCACCTTCCCCTGGAGGTGGCTTACCAGCGTGGCTACCTCAACAAGGACACG
  CACGACCAGCTGTCAGAGCCCAGCGAGGTGCGCAGCTACGTGGACCCGTCCACCGACGAG
  CGCCTCAGCTACACGCAGCTGCTCAGGCGGTGCCGTCGTGACGACGGCACCGGCCAGCTG
  CTCCTGCCACTGTCGGACGCCCGCAAGCTGACCTTCCGTGGCCTGCGGAAGCAGATCACC
  ATGGAGGAGCTGGTGCGCTCGCAGGTCATGGACGAGGCCACGGCGCTGCAGCTGCGGGAG
  GGCCTGACCTCCATCGAGGAGGTCACCAAGAACTTGCAGAAGTTCCTGGAAGGCACCAGC
  TGCATCGCTGGTGTCTTCGTGGACGCCACCAAGGAACGGCTCTCGGTGTACCAGGCCATG
  AAGAAGGGCATCATCCGCCCCGGCACAGCCTTTGAGCTCCTGGAGGCGCAGGCGGCCACC
  GGTTACGTCATCGACCCCATCAAGGGACTGAAGCTGACGGTGGAGGAGGCTGTGCGTATG
  GGCATTGTGGGCCCCGAGTTCAAGGACAAGCTGCTGTCGGCCGAGCGCGCCGTCACTGGG
  TACAAGGACCCCTACTCTGGGAAGCTCATCTCCCTCTTCCAGGCCATGAAGAAGGGCCTG
  ATCCTGAAGGACCATGGCATCCGCCTGCTGGAGGCCCAGATCGCCACGGGCGGCATCATC
  GACCCTGAGGAGAGCCACCGGCTGCCCGTGGAGGTGGCCTACAAGCGCGGCCTCTTCGAT
  GAGGAGATGAACGAGATCCTGACCGACCCCTCGGACGACACCAAGGGCTTCTTTGACCCT
  AACACGGAGGAGAACCTCACCTACCTGCAGCTGATGGAGCGTTGTATCACTGACCCCCAG
  ACGGGCCTGTGTCTCTTGCCGCTGAAGGAGAAGAAGCGGGAGCGGAAGACGTCCTCCAAG
  TCCTCCGTGCGCAAGCGCCGAGTGGTCATCGTGGACCCCGAGACGGGCAAGGAGATGTCA
  GTGTACGAGGCCTACCGCAAGGGCCTGATTGACCACCAGACGTACCTGGAGCTGTCCGAG
  CAGGAGTGCGAGTGGGAGGAGATCACCATCTCCTCCTCGGACGGCGTGGTCAAGTCCATG
  ATCATCGACCGCCGCTCCGGGCGCCAGTACGACATCGATGATGCCATCGCCAAGAACCTC
  ATCGACCGCTCGGCACTGGACCAGTACCGCGCCGGCACGCTCTCCATCACCGAGTTCGCC
  GACATGCTCTCGGGCAACGCCGGTGGTTTCCGCTCCCGTTCCTCCTCGGTGGGATCCTCC
  TCCTCCTACCCCATCAGCCCCGCCGTCTCCAGGACCCAGCTGGCCTCCTGGTCAGACCCC
  ACTGAGGAGACGGGCCCCGTGGCTGGCATCCTGGACACGGAGACGCTGGAGAAGGTGTCC
  ATCACCGAGGCCATGCACCGGAACCTGGTGGATAACATCACGGGGCAGCGGCTGCTGGAG
  GCGCAGGCCTGCACCGGGGGCATCATCGACCCCAGCACCGGTGAGCGCTTCCCTGTCACC
  GACGCCGTCAACAAGGGCCTGGTGGACAAGATCATGGTGGACCGCATCAACCTGGCCCAG
  AAGGCCTTCTGCGGCTTCGAGGACCCACGCACCAAGACCAAGATGTCGGCCGCCCAGGCC
  CTGAAGAAGGGCTGGCTCTACTACGAGGCCGGCCAGCGCTTCCTGGAGGTGCAGTACCTG
  ACCGGCGGCTTGATCGAGCCCGACACGCCGGGCCGCGTGCCCCTGGACGAGGCCCTGCAG
  CGCGGCACGGTGGACGCCCGCACCGCACAGAAGCTGCGTGACGTGGGCGCCTACTCCAAG
  TACCTCACCTGCCCTAAGACCAAGCTCAAGATCTCCTATAAGGACGCGCTGGACCGCAGC
  ATGGTGGAGGAGGGCACGGGGCTGCGGCTGCTGGAGGCTGCCGCGCAGTCCACCAAGGGC
  TACTACAGCCCCTACAGCGTCAGCGGCTCCGGCTCTACCGCTGGCTCCCGCACCGGCTCG
  CGCACCGGCTCCCGGGCCGGCTCCCGCCGCGGCAGCTTTGACGCCACCGGCTCCGGCTTC
  TCCATGACCTTCTCTTCATCCTCCTACTCCTCCTCGGGCTACGGCCGCCGCTACGCCTCG
  GGGTCCTCGGCCTCCCTGGGGGGCCCTGAGTCTGCCGTGGCCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_000445
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000445.2, NP_000436.2
• RefSeq Size: 14755 bp
• RefSeq ORF: 13725 bp
• Locus ID: 5339
• Cytogenetics: 8q24.3
• Protein Families: Druggable Genome
• Gene Summary: 'Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes (reviewed in PMID: 9701547, 11854008, and 17499243). Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans (PMID: 8633055, 8698233). Until 2010, this locus was named plectin 1 (symbol PLEC1 in human; Plec1 in mouse and rat) and the gene product had been referred to as "hemidesmosomal protein 1" or "plectin 1, intermediate filament binding 500kDa". These names were superseded by plectin. The plectin gene locus in mouse on chromosome 15 has been analyzed in detail (PMID: 10556294, 14559777), revealing a genomic exon-intron organization with well over 40 exons spanning over 62 kb and an unusual 5' transcript complexity of plectin isoforms. Eleven exons (1-1j) have been identified that alternatively splice directly into a common exon 2 which is the first exon to encode plectin's highly conserved actin binding domain (ABD). Three additional exons (-1, 0a, and 0) splice into an alternative first coding exon (1c), and two additional exons (2alpha and 3alpha) are optionally spliced within the exons encoding the acting binding domain (exons 2-8). Analysis of the human locus has identified eight of the eleven alternative 5' exons found in mouse and rat (PMID: 14672974); exons 1i, 1j and 1h have not been confirmed in human. Furthermore, isoforms lacking the central rod domain encoded by exon 31 have been detected in mouse (PMID:10556294), rat (PMID: 9177781), and human (PMID: 11441066, 1'
  Transcript Variant: This variant (1) contains the 5'-most coding exon (exon 1c) and encodes isoform 1c.