IL5RA (NM_000564) Human Untagged Clone

CAT#: SC300097

IL5RA (untagged)-Human interleukin 5 receptor, alpha (IL5RA), transcript variant 1


  "NM_000564" in other vectors (4)

Reconstitution Protocol

USD 710.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol IL5RA
Synonyms CD125; CDw125; HSIL5R3; IL5R
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_000564 edited
CGAATTCGTCGAGAGCGGACGGTTGCTCTGTACAAATCCTCCTCCATATTTGCTTAGAGA
AAACGTGTTGCCATCCCATCATGAAGGAAGCTGCCTGAGAGTTTTTAACCATTACAGCCG
TGATGATGAAAGAGTGAAGAACCGCCTCTAAGTTAAAAAGTGCACCCAGAGATAAGGTTC
GTTCTCAATGCTCTGCCGCTGCTTCTCATCGCATGGCCACCGCATTTCTCAGGCCAGGCA
CATTGAGCATTGGTCCTGTGCCTGACGCTATGCTAGATGCTGGGGTTGCAGCCACGAGCA
TAGACACGACAGACACGGTCCTCGCCATCTTCTGTTGAGTACTGGTCGGAACAAGAGGAT
CGTCTGTAGACAGGATATGATCATCGTGGCGCATGTATTACTCATCCTTTTGGGGGCCAC
TGAGATACTGCAAGCTGACTTACTTCCTGATGAAAAGATTTCACTTCTCCCGCCTGTCAA
TTTCACCATTAAAGTTACTGGTTTGGCTCAAGTTCTTTTACAATGGAAACCAAATCCTGA
TCAAGAGCAAAGGAATGTTAATCTAGAATATCAAGTGAAAATAAACGCTCCAAAAGAAGA
TGACTATGAAACCAGAATCACTGAAAGCAAATGTGTAACCATCCTCCACAARGGCTTTTC
AGCAAGTGTGCGGACCATCCTGCAGAACGACCACTCACTACTGGCCAGCAGCTGGGCTTC
TGCTGAACTTCATGCCCCACCAGGGTCTCCTGGAACCTCAATTGTGAATTTAACTTGCAC
CACAAACACTACAGAAGACAATTATTCACGTTTAAGGTCATACCAAGTTTCCCTTCACTG
CACCTGGCTTGTTGGCACAGATGCCCCTGAGGACACGCAGTATTTTCTCTACTATAGGTA
TGGCTCTTGGACTGAAGAATGCCAAGAATACAGCAAAGACACACTGGGGAGAAATATCGC
ATGCTGGTTTCCCAGGACTTTTATCCTCAGCAAAGGGCGTGACTGGCTTGCGGTGCTTGT
TAACGGCTCCAGCAAGCACTCTGCTATCAGGCCCTTTGATCAGCTGTTTGCCCTTCACGC
CATTGATCAAATAAATCCTCCACTGAATGTCACAGCAGAGATTGAAGGAACTCGTCTCTC
TATCCAATGGGAGAAACCAGTGTCTGCTTTTCCAATCCATTGCTTTGATTATGAAGTAAA
AATACACAATACAAGGAATGGATATTTGCAGATAGAAAAATTGATGACCAATGCATTCAT
CTCAATAATTGATGATCTTTCTAAGTACGATGTTCAAGTGAGAGCAGCAGTGAGCTCCAT
GTGCAGAGAGGCAGGGCTCTGGAGTGAGTGGAGCCAACCTATTTATGTGGGAAATGATGA
ACACAAGCCCTTGAGAGAGTGGTTTGTCATTGTGATTATGGCAACCATCTGCTTCATCTT
GTTAATTCTCTCGCTTATCTGTAAAATATGTCATTTATGGATCAAGTTGTTTCCACCAAT
TCCAGCACCAAAAAGTAATATCAAAGATCTCTTTGTAACCACTAACTATGAGAAAGCTGG
GTCCAGTGAGACGGAAATTGAAGTCATCTGTTATATAGAGAAGCCTGGAGTTGAGACCCT
GGAGGATTCTGTGTTTTGACTGTCACTTTGGCATCCTCTGATGAACTCACACATGCCTCA
GTGCCTCAGTGAAAAGAACAGGGATGCTGGCTCTAAGGGC
Restriction Sites Please inquire     
ACCN NM_000564
Insert Size 1800 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The ORF of this clone has been fully sequenced and found to be a perfect match to NM_000564.2.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000564.2, NP_000555.2
RefSeq Size 2367 bp
RefSeq ORF 1263 bp
Locus ID 3568
Cytogenetics 3p26.2
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway
Gene Summary 'The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1 and 4 both encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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