CNTF (NM_000614) Human Untagged Clone

CAT#: SC300108

CNTF (untagged)-Human ciliary neurotrophic factor (CNTF)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CNTF
• Synonyms: HCNTF
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000614 edited
  CACATCTCTTATTTGGACCAGTATAGACAGAAGTAAACCCAGCTGACTTGTTTCCTGGGA
  CAGTTGAGTTAAGGGATGGCTTTCACAGAGCATTCACCGCTGACCCCTCACCGTCGGGAC
  CTCTGTAGCCGCTCTATCTGGCTAGCAAGGAAGATTCGTTCAGACCTGACTGCTCTTACG
  GAATCCTATGTGAAGCATCAGGGCCTGAACAAGAACATCAACCTGGACTCTGCGGATGGG
  ATGCCAGTGGCAAGCACTGATCAGTGGAGTGAGCTGACCGAGGCAGAGCGACTCCAAGAG
  AACCTTCAAGCTTATCGTACCTTCCATGTTTTGTTGGCCAGGCTCTTAGAAGACCAGCAG
  GTGCATTTTACCCCAACCGAAGGTGACTTCCATCAAGCTATACATACCCTTCTTCTCCAA
  GTCGCTGCCTTTGCATACCAGATAGAGGAGTTAATGATACTCCTGGAATACAAGATCCCC
  CGCAATGAGGCTGATGGGATGCCTATTAATGTTGGAGATGGTGGTCTCTTTGAGAAGAAG
  CTGTGGGGCCTAAAGGTGCTGCAGGAGCTTTCACAGTGGACAGTAAGGTCCATCCATGAC
  CTTCGTTTCATTTCTTCTCATCAGACTGGGATCCCAGCACGTGGGAGCCATTATATTGCT
  AACAACAAGAAAATGTAGCAGTTAGTCCCTTCTCTCTTCCTTGCTTTCTCTTCTAATGGA
  ATATGCGTAGTTCCCTGGGGCCTCGCTTTCCCATCTTAAATTTCTAAAAACAGTTAAGAC
  AACAGGCATTTTCTTTCTTTTTTCTCTGACCACCTGCAGCCTGTTGAAGGACTACAGGTA
  TTTTCATCAAGTAGCGTTGGAGACATACACAAATGGGCATACAAGTTTAGCCTGGGGGGT
  GTGATTTGTGTGCGTGCTTGCATGTGCTGCAGGTGTAAGAGAGTGGGAGCAGGGACAACG
  TCCTTCCACTTCAGGGTTCTAACCTTTCTAACCCACTAAGTAACCTCTACAGGCATTTAA
  CTGCCTTACAGACAGAATATACATATGTTAATTCTAGTCCTGGATGACTCGGTCTGAGAA
  GATTCAATTTAAAATCAGACTCTTTAGTTGATTTAAACTCTTAGAGAATAAGAATAATAA
  TGGCTAACTTTTATTATCTTCTATATTAAGGCAGTATGCCAAGGGTCTTTATGTATATTA
  TGTACAGCGTTTACAACCTTGTGAGCAAGGTGGTGTTACTCCCATTAGGTAGATGAGAAA
  ACAGGCTCACAGAGATTTGGTTAAGCTCACACAGCTAACAAGTAGCACACTGAGTTTGAA
  CACAGATCATTCTCCTTGTAAAAGCCTATGTGCCTTTCACTTTAGAGGCTTGATCATGAA
  TCACTGCACCTCTTTGTCACAGGGTGTTGGAAGATGCATCCATGTAATCTATTCCCATCG
  CTGGAAAACAGCTGCTGTTAGATGTCCTCAGAAGTCAGTTGCAAATTTTAGCGTTAAAGT
  CAGGATTTATTGTTCATACTTGGCGGTGAGGAGGGCAGCTGGAGATCTTAAGATTCCATT
  TTGGAAAATGATTAGGCCCGCCAAACTTCTGAACTTTGGAAGCTGGGGATGTTTAGTAAT
  ACAGCCTGGTTTTCAAGTACTCACTAAAAGTTCTCAAATATTGGGTTGGGCACGGCTTAT
  ACCAGGTTACCTCACTTTTAATTAGTGATGCAGGCAGTGTAACCCAAGCATTTGTGGACA
  ATGAGTGGAATACTAAAGTTAAAAAGTCAAACTTTCACCTCAGATTTTCTGGACTTAGTC
  ATGAGGAGAGGGTGAGGCCCACTCTGTTCCTACTGGAGATACCAGAGACTCTGAAACTAT
  AGAATAAAGCCTCTGTGCTGCACAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_000614
• ORF Size: 603 bp
• Insert Size: 2000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_000614.2.

Reference Data

• RefSeq: NM_000614.2, NP_000605.1
• RefSeq Size: 1891
• RefSeq ORF: 603
• Locus ID: 1270
• Protein Families: Druggable Genome
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]