MAD2L1 binding protein (MAD2L1BP) (NM_001003690) Human Untagged Clone

CAT#: SC300518

MAD2L1BP (untagged)-Human MAD2L1 binding protein (MAD2L1BP), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAD2L1BP
• Synonyms: CMT2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001003690 edited
  ATGGCCCGCGTGCCGCTGGGGCGGAGTCTCACTCTGTCACCCAGGCTGGAGCACAATGGC
  ATGACCTCAGCTCACCACAACTTCCGCCTCCCAGGTTCAAGGGATTCTCCTGCCTCAGCC
  TCCCAAGTAGCTGAGATTATAGATTTGGAGTGGTATGAGAAGTCCGAAGAAACTCACGCC
  TCCCAGATAGAACTACTTGAGACAAGCTCTACGCAGGAACCTCTCAACGCTTCGGAGGCC
  TTTTGCCCAAGAGACTGCATGGTACCAGTGGTGTTTCCTGGGCCTGTGAGCCAGGAAGGC
  TGCTGTCAGTTTACTTGTGAACTTCTAAAGCATATCATGTATCAACGCCAGCAGCTCCCT
  CTGCCCTATGAACAGCTTAAGCACTTTTACCGAAAACCTTCTCCCCAGGCAGAGGAGATG
  CTGAAGAAGAAACCTCGGGCCACCACTGAGGTGAGCAGCAGGAAATGCCAACAAGCCCTG
  GCAGAACTGGAGAGTGTCCTCAGCCACCTGGAGGACTTCTTTGCACGGACACTAGTACCG
  CGAGTGCTGATTCTCCTTGGGGGCAATGCCCTAAGCCCCAAGGAGTTCTATGAACTCGAC
  TTGTCTCTGCTGGCCCCCTACAGCGTGGACCAGAGCCTGAGCACAGCAGCTTGTTTGCGC
  CGTCTCTTCCGAGCCATATTCATGGCTGATGCCTTTAGCGAGCTTCAGGCTCCTCCACTC
  ATGGGCACCGTCGTCATGGCACAGGGACACCGCAACTGTGGAGAAGATTGGTTTCGACCC
  AAGCTCAACTATCGAGTGCCCAGCCGGGGCCATAAACTGACTGTGACCCTGTCATGTGGC
  AGACCTTCCATCCGAACCACGGCTTGGGAAGACTACATTTGGTTCCAGGCACCAGTGACA
  TTTAAAGGCTTCCGCGAGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001003690 unedited
  NCGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCATGGCCCGCGTGCCG
  CTGGGGCGGAGTCTCACTCTGTCACCCAGGCTGGAGCACAATGGCATGACCTCAGCTCAC
  CACAACTTCCGCCTCCCAGGTTCAAGGGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGAG
  ATTATAGATTTGGAGTGGTATGAGAAGTCCGAAGAAACTCACGCCTCCCAGATAGAACTA
  CTTGAGACAAGCTCTACGCAGGAACCTCTCAACGCTTCGGAGGCCTTTTGCCCAAGAGAC
  TGCATGGTACCAGTGGTGTTTCCTGGGCCTGTGAGCCAGGAAGGCTGCTGTCAGTTTACT
  TGTGAACTTCTAAAGCATATCATGTATCAACGCCAGCAGCTCCCTCTGCCCTATGAACAG
  CTTAAGCACTTTTACCGAAAACCTTCTCCCCAGGCAGAGGAGATGCTGAAGAAGAAACCT
  CGGGCCACCACTGAGGTGAGCAGCAGGAAATGCCAACAAGCCCTGGCAGAACTGGAGAGT
  GTCCTCAGCCACCTGGAGGACTTCTTTGCACGGACACTAGTACCGCGAGTGCTGATTCTC
  CTTGGGGGCAATGCCCTAAGCCCCAAGGAGTTCTATGAACTCGACTTGTCTCTGCTGGCC
  CCCTACAGCGTGGACCAGAGCCTGAGCACAGCAGCTTGTTTGCGCCGTCTCTTCCGAGCC
  ATATTCATGGCTGATGCCTTTAGCGAGCTTCAGGCTCCTCCACTCATGGGCACCGTCGTC
  ATGGCACAGGGACACCGCAACTGTGGAGAAAGATTGGNTTCGACCCAAGCTCAACTATCG
  AGTGCCCAGCCGGNGCCATAAACTGACTGTGACCCTGTCATGTGGCAGACCTTNCA
  
• Restriction Sites: Please inquire
• ACCN: NM_001003690
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001003690.1, NP_001003690.1
• RefSeq Size: 1550 bp
• RefSeq ORF: 921 bp
• Locus ID: 9587
• Cytogenetics: 6p21.1
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).