ALG11 (NM_001004127) Human Untagged Clone

CAT#: SC300606

ALG11 (untagged)-Human asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) (ALG11), transcript variant A

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALG11
• Synonyms: CDG1P; GT8
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001004127, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCCGGCGAAAGGAGCTGGTGCCTGTGCAAGTTGTTGAGGTTTTTTTATTCATTATTCTTCCCTG
  GGCTCATTGTATGTGGAACTTTATGTGTGTGTTTGGTCATTGTCCTTTGGGGAATCAGACTGCTGCTACA
  GAGAAAGAAAAAATTAGTGTCAACTAGCAAAAATGGGAAAAATCAAATGGTGATTGCATTTTTTCATCCA
  TACTGCAATGCTGGTGGAGGAGGAGAAAGAGTTTTATGGTGTGCTTTAAGAGCCCTGCAGAAAAAGTATC
  CTGAAGCAGTTTATGTTGTTTATACCGGCGATGTTAATGTCAACGGTCAACAGATACTAGAAGGTGCTTT
  CAGAAGATTTAACATCAGATTAATTCACCCAGTGCAGTTTGTTTTTTTAAGGAAACGCTATCTTGTGGAA
  GATTCACTGTATCCTCACTTCACACTGCTGGGCCAAAGTCTAGGATCCATTTTTCTTGGCTGGGAAGCTC
  TAATGCAGTGTGTTCCTGATGTTTACATTGATTCAATGGGATACGCTTTTACGCTTCCTCTGTTTAAGTA
  TATAGGGGGTTGCCAAGTTGGAAGCTATGTTCATTATCCTACTATCAGCACCGACATGCTCTCTGTAGTG
  AAGAATCAAAATATTGGATTTAATAATGCAGCCTTCATTACCAGGAATCCTTTTCTCAGCAAAGTAAAGC
  TCATCTACTACTATTTATTTGCTTTTATTTATGGACTTGTTGGTTCTTGCAGTGATGTAGTCATGGTCAA
  TTCTTCTTGGACACTAAACCATATTCTCTCACTATGGAAAGTTGGGAATTGCACTAACATTGTTTATCCA
  CCTTGTGATGTGCAGACATTTCTGGACATTCCCTTACATGAGAAAAAGATGACCCCAGGACATTTGCTGG
  TTTCTGTTGGCCAGTTTAGGCCGGAAAAGAATCATCCATTGCAGATCAGAGCCTTTGCTAAATTGCTGAA
  TAAGAAGATGGTTGAGTCACCTCCTTCGCTTAAACTTGTCCTCATTGGAGGTTGTCGTAACAAAGATGAT
  GAACTTAGGGTAAACCAACTGAGAAGGCTGTCTGAGGATTTAGGAGTTCAAGAATATGTGGAATTTAAAA
  TAAACATTCCATTTGATGAATTAAAGAATTATTTGTCTGAAGCAACAATTGGTCTGCATACCATGTGGAA
  CGAGCATTTTGGGATTGGAGTTGTGGAGTGTATGGCAGCTGGCACAATTATCCTTGCACACAATTCGGGG
  GGCCCAAAGCTTGACATTGTGGTTCCTCACGAAGGAGATATAACTGGCTTTCTGGCTGAGAGTGAAGAAG
  ACTATGCTGAAACTATCGCTCACATTCTTTCCATGTCTGCAGAAAAGAGACTCCAAATCAGAAAAAGTGC
  TCGTGCATCTGTAAGCAGATTCTCTGATCAGGAATTTGAAGTGACATTCCTATCATCTGTGGAAAAGTTA
  TTTAAGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001004127
• ORF Size: 1479 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001004127.2, NP_001004127.2
• RefSeq Size: 2595
• RefSeq ORF: 1479
• Locus ID: 440138
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (A) represents the longer transcript and encodes the functional protein.