TRIM37 (NM_001005207) Human Untagged Clone

CAT#: SC300846

TRIM37 (untagged)-Human tripartite motif containing 37 (TRIM37), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIM37
• Synonyms: MUL; POB1; TEF3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001005207, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGATGAACAGAGCGTGGAGAGCATTGCTGAGGTTTTCCGATGTTTCATTTGTATGGAGAAATTGCGGG
  ATGCACGCCTGTGTCCTCATTGCTCCAAACTGTGTTGTTTCAGCTGTATTAGGCGCTGGCTGACAGAGCA
  GAGAGCTCAATGTCCTCATTGCCGTGCTCCACTCCAGCTACGAGAACTAGTAAATTGTCGTTGGGCAGAA
  GAAGTAACACAACAGCTTGATACTCTTCAACTCTGCAGTCTCACCAAACATGAAGAAAATGAAAAGGACA
  AATGTGAAAATCACCATGAAAAACTTAGTGTATTTTGCTGGACTTGTAAGAAGTGTATCTGCCATCAGTG
  TGCACTTTGGGGAGGAATGCATGGCGGACATACCTTTAAACCTTTGGCAGAAATTTATGAGCAACACGTC
  ACTAAAGTGAATGAAGAGGTAGCCAAACTTCGTCGGCGTCTCATGGAACTGATCAGCTTAGTTCAAGAAG
  TGGAAAGGAATGTAGAAGCTGTAAGAAATGCAAAAGATGAGCGTGTTCGGGAAATTAGGAATGCAGTGGA
  GATGATGATTGCACGGTTAGACACACAGCTGAAGAATAAGCTTATAACACTGATGGGTCAGAAGACATCT
  CTAACCCAAGAAACAGAGCTTTTGGAATCCTTACTTCAGGAGGTGGAGCACCAGTTGCGGTCTTGTAGTA
  AGAGTGAGTTGATATCTAAGAGCTCAGAGATCCTTATGATGTTTCAGCAAGTTCATCGGAAGCCCATGGC
  ATCTTTTGTTACCACTCCTGTTCCACCAGACTTTACCAGTGAATTAGTGCCATCTTACGATTCAGCTACT
  TTTGTTTTAGAGAATTTCAGCACTTTGCGTCAGAGAGCAGATCCTGTTTACAGTCCACCTCTTCAAGTTT
  CAGGACTTTGCTGGAGGTTAAAAGTTTACCCAGATGGAAATGGAGTTGTGCGAGGTTACTACTTATCTGT
  GTTTCTGGAGCTCTCAGCTGGCTTGCCTGAAACTTCTAAATATGAATATCGTGTAGAGATGGTTCACCAG
  TCCTGTAATGATCCTACAAAAAATATCATTCGAGAATTTGCATCTGACTTTGAAGTTGGAGAATGCTGGG
  GCTATAATAGATTTTTCCGTTTGGACTTACTCGCAAATGAAGGATACTTGAATCCACAAAATGATACAGT
  GATTTTAAGGTTTCAGGTACGTTCACCAACTTTCTTTCAAAAATCCCGGGACCAGCATTGGTACATTACT
  CAGTTGGAAGCTGCACAGACTAGTTATATCCAACAAATAAACAACCTTAAAGAGAGACTTACTATTGAGC
  TGTCTCGAACTCAGAAGTCAAGAGATTTGTCACCACCAGATAACCATCTTAGCCCCCAAAATGATGATGC
  TCTGGAGACACGAGCTAAGAAGTCTGCATGCTCTGACATGCTTCTCGAAGGTGGTCCTACTACAGCTTCT
  GTAAGAGAGGCCAAAGAGGATGAAGAAGATGAGGAGAAGATTCAGAATGAAGATTATCATCACGAGCTTT
  CAGATGGAGATCTGGATCTGGATCTTGTTTATGAGGATGAAGTAAATCAGCTCGATGGCAGCAGTTCCTC
  TGCTAGTTCCACAGCAACAAGTAATACAGAAGAAAATGATATTGATGAAGAAACTATGTCTGGAGAAAAT
  GATGTGGAATATAACAACATGGAATTAGAAGAGGGAGAACTCATGGAAGATGCAGCTGCTGCAGGACCCG
  CAGGTAGTAGCCATGGTTATGTGGGTTCCAGTAGTAGAATATCAAGAAGAACACATTTATGCTCCGCTGC
  TACCAGTAGTTTACTAGACATTGATCCATTAATTTTAATACATTTGTTGGACCTTAAGGACCGGAGCAGT
  ATAGAAAATTTGTGGGGCTTACAGCCTCGCCCACCTGCTTCACTTCTGCAGCCCACAGCATCATATTCTC
  GAAAAGATAAAGACCAAAGGAAGCAACAGGCAATGTGGCGAGTGCCCTCTGATTTAAAGATGCTAAAAAG
  ACTCAAAACTCAAATGGCCGAAGTTCGATGTATGAAAACTGATGTAAAGAATACACTTTCAGAAATAAAA
  AGCAGCAGTGCTGCTTCTGGAGACATGCAGACAAGCCTTTTTTCTGCTGACCAGGCAGCTCTGGCTGCAT
  GTGGAACTGAAAACTCTGGCAGATTGCAGGATTTGGGAATGGAACTCCTGGCAAAGTCATCAGTTGCCAA
  TTGTTACATACGAAACTCCACAAATAAGAAGAGTAATTCGCCCAAGCCAGCTCGATCCAGTGTAGCAGGT
  AGTCTATCACTTCGAAGAGCAGTGGACCCTGGAGAAAATAGTCGTTCAAAGGGAGACTGTCAGACTCTGT
  CTGAAGGCTCCCCAGGAAGCTCTCAGTCTGGGAGCAGGCACAGTTCTCCCCGAGCCTTGATACATGGCAG
  TATCGGTGATATTCTGCCAAAAACTGAAGACCGGCAGTGTAAAGCTTTGGATTCAGATGCTGTTGTGGTT
  GCAGTTTTCAGTGGCTTGCCTGCGGTTGAGAAAAGGAGGAAAATGGTCACCTTGGGGGCTAATGCTAAAG
  GAGGTCATCTGGAAGGACTGCAGATGACTGATTTGGAAAATAATTCTGAAACTGGAGAGTTACAGCCTGT
  ACTACCTGAAGGAGCTTCAGCTGCCCCTGAAGAAGGAATGAGTAGCGACAGTGACATTGAATGTGACACT
  GAGAATGAGGAGCAGGAAGAGCATACCAGTGTGGGCGGGTTTCACGACTCCTTCATGGTCATGACACAGC
  CCCCGGATGAAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAA
  TACAGATGAAAATAGTGGAAGATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001005207
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001005207.3, NP_001005207.1
• RefSeq Size: 3639 bp
• RefSeq ORF: 2895 bp
• Locus ID: 4591
• Cytogenetics: 17q22
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: 'This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. Mutations in this gene are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. TRIM37 localizes in peroxisomal membranes, and has been implicated in human peroxisomal biogenesis disorders. [provided by RefSeq, Jul 2020]'
  Transcript Variant: This variant (2) and variant 1 encode the same isoform (a).