KDM2B (NM_001005366) Human Untagged Clone

CAT#: SC300925

KDM2B (untagged)-Human lysine (K)-specific demethylase 2B (KDM2B), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KDM2B
• Synonyms: CXXC2; Fbl10; FBXL10; JHDM1B; PCCX2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001005366, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGCAGAGAAAGACTCTGGAAGAAGATTGCGCCCGATTGACCGCCAGCGATACGACGAGAACGAGG
  ACTTGTCGGACGTGGAGGAGATCGTCAGCGTCCGCGGCTTCAGCCTGGAGGAGAAGCTTCGCAGCCAGCT
  GTACCAGGGGGACTTCGTGCACGCCATGGAGGGCAAAGATTTCAACTATGAGTACGTACAGAGAGAAGCT
  CTCAGGGTTCCCCTGATATTTCGAGAAAAGGATGGACTGGGAATTAAGATGCCTGACCCTGATTTCACAG
  TCCGAGACGTCAAACTCCTAGTGGGGAGCCGGCGGCTTGTGGACGTGATGGATGTGAACACCCAGAAGGG
  CACGGAGATGAGCATGTCCCAGTTTGTGCGTTACTACGAGACGCCCGAGGCCCAGCGGGACAAGCTGTAC
  AACGTCATCAGCCTAGAGTTCAGCCACACCAAGCTGGAGCACTTGGTCAAGCGTCCGACTGTGGTAGACC
  TGGTGGACTGGGTGGACAACATGTGGCCCCAGCATCTGAAGGAGAAGCAGACAGAAGCCACGAACGCCAT
  TGCAGAGATGAAGTACCCGAAAGTGAAAAAGTACTGTCTGATGAGCGTGAAAGGTTGTTTCACCGACTTC
  CACATCGACTTTGGAGGCACTTCCGTTTGGTACCATGTTTTCCGGGGTGGGAAGATTTTTTGGCTGATTC
  CTCCAACGCTGCACAATTTGGCGCTGTACGAGGAGTGGGTGCTGTCAGGCAAACAGAGTGACATCTTTCT
  GGGAGACCGTGTGGAACGATGCCAAAGAATTGAGCTGAAGCAGGGCTACACATTTTTCATCCCTTCCGGT
  TGGATCCATGCCGTCTACACCCCTGTAGACTCTTTGGTGTTCGGCGGAAACATCCTGCACAGCTTTAACG
  TGCCCATGCAGCTGCGGATCTACGAGATCGAGGACAGGACGCGGGTGCAGCCCAAATTCCGTTACCCCTT
  CTACTATGAGATGTGCTGGTATGTCCTGGAGAGATACGTGTACTGTGTGACCCAGCGCTCCCACCTCACT
  CAGGAATACCAGAGGGAGTCGATGCTTATTGATGCCCCGAGGAAGCCCAGCATAGACGGCTTCTCTTCGG
  ATTCCTGGCTGGAGATGGAGGAGGAGGCCTGTGATCAGCAGCCTCAGGAGGAGGAGGAGAAGGACGAGGA
  GGGCGAGGGCAGGGACAGGGCACCCAAACCGCCCACCGATGGCTCCACTTCACCCACCAGCACGCCCTCT
  GAGGACCAGGAGGCCCTCGGGAAGAAGCCCAAAGCACCTGCCCTGCGATTCCTCAAAAGGACTTTGTCTA
  ATGAGTCGGAGGAAAGTGTGAAGTCCACCACATTGGCCGTAGACTACCCCAAGACCCCCACCGGCTCTCC
  CGCCACGGAGGTCTCTGCCAAATGGACCCATCTCACTGAGTTTGAACTGAAGGGCCTGAAAGCTCTGGTG
  GAGAAACTGGAATCCCTCCCGGAGAACAAGAAGTGTGTCCCCGAGGGCATCGAGGACCCCCAGGCACTCC
  TGGAGGGTGTGAAGAACGTCCTGAAGGAGCACGCAGATGATGACCCTAGTCTGGCCATCACTGGGGTCCC
  TGTGGTGACTTGGCCAAAGAAGACTCCAAAGAACCGGGCTGTGGGTCGGCCCAAGGGGAAGCTGGGCCCG
  GCCTCCGCGGTGAAGTTGGCCGCCAACCGGACAACGGCAGGAGCTCGGCGGCGCCGGACGCGATGCCGCA
  AGTGCGAGGCCTGCCTGCGGACCGAGTGCGGAGAGTGCCACTTCTGCAAGGACATGAAGAAGTTCGGGGG
  CCCCGGGCGCATGAAGCAGAGCTGCATCATGCGGCAGTGCATCGCGCCAGTGCTGCCCCACACCGCCGTG
  TGCCTTGTGTGTGGCGAGGCGGGGAAGGAAGACACGGTGGAAGAGGAGGAAGGCAAGTTTAACCTCATGC
  TCATGGAGTGCTCCATCTGCAATGAAATCATCCACCCTGGATGCCTTAAGATTAAGGAGTCAGAGGGTGT
  GGTCAACGACGAGCTTCCAAACTGCTGGGAGTGTCCGAAGTGTAACCACGCCGGCAAGACCGGGAAACAA
  AAGCGTGGCCCTGGCTTTAAGTACGCCTCCAACCTGCCCGGCTCCCTGCTCAAGGAGCAGAAGATGAACC
  GGGACAACAAGGAAGGGCAGGAACCTGCCAAGCGGAGGAGTGAGTGTGAGGAGGCGCCCCGGCGCAGGTC
  GGATGAGCACTCGAAGAAGGTGCCGCCGGACGGCCTTCTGCGCAGAAAGTCTGACGACGTGCACCTGAGG
  AAGAAGCGGAAATACGAGAAGCCCCAGGAGCTGAGTGGACGCAAGCGGCTCAAACCTGGCAAAGAAGATA
  AGCTTTTCAGGAAAAAGCGGCGGTCCTGGAAGAACGCCGAGGACCGCATGGCGCTGGCCAACAAGCCCCT
  CCGGCGCTTCAAGCAGGAACCCGAGGACGAACTGCCCGAGGCGCCCCCCAAGACCAGGGAGAGCGACCAC
  TCCCGCTCCAGCTCCCCCACCGCGGGACCCAGCACCGAAGGGGCCGAGGGCCCGGAGGAGAAGAAGAAGG
  TGAAGATGCGCCGGAAGCGGCGGCTTCCCAACAAGGAGCTGAGCAGGGAGCTGAGCAAGGAGCTCAACCA
  CGAGATCCAGAGGACGGAGAACAGCCTGGCCAACGAGAACCAGCAGCCCATCAAGTCGGAGCCTGAGAGC
  GAGGGCGAGGAGCCCAAGCGGCCCCCGGGCATCTGCGAGCGTCCCCACCGCTTCAGCAAGGGGCTCAACG
  GCACCCCCCGGGAGCTGCGGCACCAGCTGGGGCCCAGCCTGCGCAGCCCGCCCCGTGTCATCTCCCGGCC
  CCCACCCTCCGTGTCCCCGCCCAAGTGTATCCAGATGGAGCGCCATGTGATCCGGCCACCCCCCATCAGC
  CCCCCGCCTGACTCGCTACCCCTGGACGATGGGGCAGCCCACGTCATGCACAGGGAGGTGTGGATGGCCG
  TCTTCAGCTACCTCAGCCACCAAGACCTGTGTGTGTGCATGCGGGTCTGCAGGACCTGGAACCGCTGGTG
  CTGCGATAAGCGGTTGTGGACCCGCATTGACCTGAACCACTGCAAGTCTATCACACCCCTGATGCTGAGT
  GGCATCATCCGGCGACAGCCCGTCTCCCTCGACCTCAGCTGGACCAATATCTCCAAGAAGCAGCTGAGCT
  GGCTCATCAACCGGCTGCCTGGGCTCCGGGACTTGGTGCTGTCAGGCTGCTCATGGATCGCGGTCTCGGC
  CCTTTGCAGCTCCAGTTGTCCGCTGCTCCGGACCCTGGATGTCCAGTGGGTGGAGGGACTAAAGGATGCC
  CAGATGCGGGATCTCCTGTCCCCGCCCACAGACAACAGGCCAGGTCAGATGGACAATCGGAGCAAGCTCC
  GGAACATCGTGGAGCTGCGCCTGGCAGGCCTGGACATCACAGATGCCTCCCTGCGGCTCATCATCCGCCA
  CATGCCCCTGCTCTCCAAGCTCCACCTCAGTTACTGTAACCACGTCACCGACCAGTCTATCAACCTGCTC
  ACTGCTGTTGGCACCACCACCCGAGACTCCTTAACCGAGATCAACCTGTCTGACTGCAATAAGGTCACTG
  ATCAGTGCCTGTCCTTCTTCAAACGCTGTGGAAACATCTGTCATATTGACCTGAGGTACTGCAAGCAAGT
  CACCAAGGAAGGCTGTGAGCAGTTCATAGCCGAGATGTCTTCTTTCCAAGGGAGAAGCTGTTCAACCACC
  CGTTTGGGGGATGAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001005366
• ORF Size: 3798 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001005366.1, NP_001005366.1
• RefSeq Size: 5236
• RefSeq ORF: 3798
• Locus ID: 84678
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR and coding region, as compared to variant 1. The encoded isoform b has alternate N- and C-termini and lacks an internal segment, as compared to isoform a.