RSK3 (RPS6KA2) (NM_001006932) Human Untagged Clone

CAT#: SC301116

RPS6KA2 (untagged)-Human ribosomal protein S6 kinase, 90kDa, polypeptide 2 (RPS6KA2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RPS6KA2
• Synonyms: HU-2; MAPKAPK1C; p90-RSK3; p90RSK2; pp90RSK3; RSK; RSK3; S6K-alpha; S6K-alpha2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001006932, the custom clone sequence may differ by one or more nucleotides
  ATGCCAATCGCACAGTTGCTGGAACTATGGAAAAAGATCGAGGTGGAGCCTATGGAAATA
  GAGACCACAGAGGAGGATCTCAACCTGGATGTGGAGCCCACCACAGAAGACACTGCAGAA
  GAAGAAGAAGGCGTCGTGAAGGAGATAGACATCAGCCATCATGTGAAGGAGGGCTTTGAG
  AAGGCAGATCCTTCCCAGTTTGAGCTGCTGAAGGTTTTAGGACAAGGATCCTATGGAAAG
  GTGTTCCTGGTGAGGAAGGTGAAGGGGTCCGACGCTGGGCAGCTCTACGCCATGAAGGTC
  CTTAAGAAAGCCACCCTAAAAGTTCGGGACCGAGTGAGATCGAAGATGGAGAGAGACATC
  TTGGCAGAAGTGAATCACCCCTTCATTGTGAAGCTTCATTATGCCTTTCAGACGGAAGGA
  AAGCTCTACCTGATCCTGGACTTCCTGCGGGGAGGGGACCTCTTCACCCGGCTCTCCAAA
  GAGGTCATGTTCACGGAGGAGGATGTCAAGTTCTACCTGGCTGAGCTGGCCTTGGCTTTA
  GACCATCTCCACAGCCTGGGGATCATCTACAGAGATCTGAAGCCTGAGAACATCCTCCTG
  GATGAAGAGGGGCACATTAAGATCACAGATTTCGGCCTGAGTAAGGAGGCCATTGACCAC
  GACAAGAGAGCGTACTCCTTCTGCGGGACGATCGAGTACATGGCGCCCGAGGTGGTGAAC
  CGGCGAGGACACACGCAGAGTGCCGACTGGTGGTCCTTCGGCGTGCTCATGTTTGAGATG
  CTCACGGGGTCCCTGCCGTTCCAGGGGAAGGACAGGAAGGAGACCATGGCTCTCATCCTC
  AAAGCCAAGCTGGGGATGCCGCAGTTCCTCAGTGGGGAGGCACAGAGTTTGCTGCGAGCT
  CTCTTCAAACGGAACCCCTGCAACCGGCTGGGTGCTGGCATTGACGGAGTGGAGGAAATT
  AAGCGCCATCCCTTCTTTGTGACCATAGACTGGAACACGCTGTACCGGAAGGAGATCAAG
  CCACCGTTCAAACCAGCAGTGGGCAGGCCTGAGGACACCTTCCACTTTGACCCCGAGTTC
  ACAGCGCGGACGCCCACAGACTCTCCTGGCGTCCCCCCGAGTGCAAACGCTCATCACCTG
  TTTAGAGGATTCAGCTTTGTGGCCTCAAGCCTGATCCAGGAGCCCTCACAGCAAGATCTG
  CACAAAGTCCCAGTTCACCCAATCGTGCAGCAGTTACACGGGAACAACATCCACTTCACC
  GATGGCTACGAGATCAAGGAGGACATCGGGGTGGGCTCCTACTCAGTGTGCAAGCGATGT
  GTGCATAAAGCCACAGACACCGAGTATGCCGTGAAGATCATTGATAAGAGCAAGAGAGAC
  CCCTCGGAAGAGATTGAGATCCTCCTGCGGTACGGCCAGCACCCGAACATCATCACCCTC
  AAGGATGTCTATGATGATGGCAAGTTTGTGTACCTGGTAATGGAGCTGATGCGTGGTGGG
  GAGCTCCTGGACCGCATCCTCCGGCAGAGATACTTCTCGGAGCGCGAAGCCAGTGACGTC
  CTGTGCACCATCACCAAGACCATGGACTACCTCCATTCCCAGGGGGTTGTTCATCGAGAC
  CTGAAGCCGAGTAACATCCTGTACAGGGATGAGTCGGGGAGCCCAGAATCCATCCGAGTC
  TGCGACTTCGGCTTTGCCAAGCAGCTGCGCGCGGGGAACGGGCTGCTCATGACACCCTGC
  TACACGGCCAATTTCGTGGCCCCGGAGGTCCTGAAGCGTCAAGGCTATGATGCGGCGTGT
  GACATCTGGAGTTTGGGGATCCTGTTGTACACCATGCTGGCAGGATTTACCCCTTTTGCA
  AATGGGCCAGACGATACCCCTGAGGAGATTCTGGCGCGGATCGGCAGTGGGAAGTATGCC
  CTTTCTGGGGGAAACTGGGACTCGATATCTGACGCAGCTAAAGACGTCGTGTCCAAGATG
  CTCCACGTGGACCCTCATCAGCGCCTGACGGCGATGCAAGTGCTCAAACACCCGTGGGTG
  GTCAACAGAGAGTACCTGTCCCCAAACCAGCTCAGCCGACAGGACGTGCACCTGGTGAAG
  GGCGCGATGGCCGCCACCTACTTTGCTCTAAACAGAACACCTCAGGCCCCGCGGCTGGAG
  CCCGTGCTGTCATCCAACCTGGCTCAGCGCAGAGGCATGAAGAGACTCACGTCCACGCGG
  CTGTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001006932
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001006932.1, NP_001006933.1
• RefSeq Size: 5735 bp
• RefSeq ORF: 2226 bp
• Locus ID: 6196
• Cytogenetics: 6q27
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Long-term potentiation, MAPK signaling pathway, mTOR signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation
• Gene Summary: 'This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternative splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2016]'
  Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region compared to variant 1, and initiates translation at an alternate start codon. The encoded isoform (b) has a distinct N-terminus and is longer than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.