Glycoprotein 2 (GP2) (NM_001007241) Human Untagged Clone

CAT#: SC301182

GP2 (untagged)-Human glycoprotein 2 (zymogen granule membrane) (GP2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GP2
• Synonyms: ZAP75
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001007241 edited
  GGCCAGAGGAGGAACGCTTTGTGTTCTCATCGGAGCTGCATGGGAAGTCTGCATACAGCA
  AAGTGACCTGCATGCCTCACCTTATGGAAAGGATGGTGGGCTCTGGCCTCCTGTGGCTGG
  CCTTGGTCTCCTGCATTCTGACCCAGGCATCTGCAGTGCAGCGAGTTCCACGAGACCCAT
  CCACTGTGGAGGACAAGTGTGAGAAGGCCTGCCGCCCCGAGGAGGAGTGCCTTGCCCTCA
  ACAGCACCTGGGGCTGTTTCTGCAGACAGGACCTCAATAGTTCTGATGTCCACAGTTTGC
  AGCCTCAGCTAGACTGTGGGCCCAGGGAGATCAAGGTGAAGGTGGACAAATGTTTGCTGG
  GAGGCCTGGGTTTGGGGGAGGAGGTCATTGCCTACCTGCGAGACCCAAACTGCAGCAGCA
  TCTTGCAGACAGAGGAGAGGAACTGGGTATCTGTGACCAGCCCCGTCCAGGCTAGTGCCT
  GCAGGAACATTCTGGAGAGAAATCAAACCCATGCCATCTACAAAAACACCCTCTCCTTGG
  TCAATGATTTCATCATCAGAGACACCATCCTCAACATCAACTTCCAATGTGCCTACCCAC
  TGGACATGAAAGTCAGCCTCCAAGCTGCCTTGCAGCCCATTGTAAGTTCCCTGAACGTCA
  GTGTGGACGGGAATGGAGAGTTCATTGTCAGGATGGCCCTCTTCCAAGACCAGAACTACA
  CGAATCCTTACGAAGGGGATGCAGTTGAACTGTCTGTTGAGTCCGTGCTGTATGTGGGTG
  CCATCTTGGAACAAGGGGACACCTCCCGGTTTAACCTGGTGTTGAGGAACTGCTATGCCA
  CCCCCACTGAAGACAAGGCTGACCTTGTGAAGTATTTCATCATCAGAAACAGCTGCTCAA
  ATCAACGTGATTCCACCATCCACGTGGAGGAGAATGGGCAGTCCTCGGAAAGCCGGTTCT
  CAGTTCAGATGTTCATGTTTGCTGGACATTATGACCTAGTTTTCCTGCATTGTGAGATTC
  ATCTCTGTGATTCTCTTAATGAACAGTGCCAGCCTTCTTGCTCAAGAAGTCAAGTCCGCA
  GTGAAGTACCGGCCATCGACCTAGCCCGGGTTCTAGATTTGGGGCCCATCACTCGGAGAG
  GTGCACAGTCTCCCGGTGTCATGAATGGAACCCCTAGCACTGCAGGGTTCCTGGTGGCCT
  GGCCTATGGTCCTCCTGACTGTCCTCCTGGCTTGGCTGTTCTGAGAGCTCCGCTGAGCAT
  CTGGCCTTGAAGTTTGTGTTCTTCCCTCTGGCAATGGCTCCCTTCAGCACTTCTGCTTTC
  CACTCCAATTCACACAGGCTTGGTATTAACAGAATCAAGGCCAGGCTAGGTTAGGAAAAG
  GGAAGAGCTTTCACCTTCTTTAAAACTCTCGGCTGGGCGCAGTGGCTCATGCCTGTAATC
  CCAGCATTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGCAGTTCAAAATCAGCC
  TGGCCAAAATGCTGAAACTCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGG
  CAGGCGCCTGTAATCCCAGCTACTCGGGAGGCCAAGGCAGGAGAATTGCTCGAACTCAGG
  GGGTGGAGTTTGCAGTGAGTTGAGATTGTGCCATTGCACTCCAGCCTGGGCAACAGAGCA
  AGACTCTGTCTCAGGAAAAAAAAAAAAAAAAAAGAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001007241
• Insert Size: 1700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001007241.1.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001007241.1, NP_001007242.2
• RefSeq Size: 2007 bp
• RefSeq ORF: 1173 bp
• Locus ID: 2813
• Cytogenetics: 16p12.3
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: 'This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]'
  Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The resulting protein (isoform 3) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.