STAR (NM_001007243) Human Untagged Clone

CAT#: SC301184

STAR (untagged)-Human steroidogenic acute regulatory protein (STAR), nuclear gene encoding mitochondrial protein, transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STAR
• Synonyms: cholesterol trafficker; mitochondrial steroid acute regulatory protein; StAR-related lipid transfer (START) domain containing 1; STARD1; START domain containing 1; steroid acute regulatory protein; steroidogenic acute regula; steroidogenic acute regulator
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001007243 edited
  ATCGTCGACCCACGCGTCCGGGCAGCAGCAGCGGCGGCAGCAGCAGCGGCAGCGACCCCA
  CCACTGCCACATTTGCCAGGAAACAATGCTGCTAGCGACATTCAAGCTGTGCGCTGGGAG
  CTCCTACAGACACATGCGCAACATGAAGGGGCTGAGGCAACAGGCTGTGATGGCCATCAG
  CCAGGAGCTGAACCGGAGGGCCCTGGGGGGCCCCACCCCTAGCACGTGGATTAACCAGGT
  TCGGCGGCGGAGCTCTCTACTCGGTTCTCGGCTGGAAGAGACTCTCTACAGTGACCAGGA
  GCTGGCCTATCTCCAGCAGGGGGAGGAGGCCATGCAGAAGGCCTTGGGCATCCTTAGCAA
  CCAAGAGGGCTGGAAGAAGGAGAGTCAGCAGGACAATGGGGACAAAGTGATGAGTAAAGT
  GGTCCCAGATGTGGGCAAGGTGTTCCGGCTGGAGGTCGTGGTGGACCAGCCCATGGAGAG
  GCTCTATGAAGAGCTCGTGGAGCGCATGGAAGCAATGGGGGAGTGGAACCCCAATGTCAA
  GGAGATCAAGGTCCTGCAGAAGATCGGGGGGCCCCGTGACTTTGTGAGCGTGCGCTGTGC
  CAAGCGCCGAGGCTCCACCTGTGTGCTGGCTGGCATGGCCACAGACTTCGGGAACATGCC
  TGAGCAGAAGGGTGTCATCAGGGCGGAGCACGGTCCCACTTGCATGGTGCTTCACCCGTT
  GGCTGGAAGTCCCTCTAAGACCAAACTTACGTGGCTACTCAGCATCGACCTCAAGGGGTG
  GCTGCCCAAGAGCATCATCAACCAGGTCCTGTCCCAGACCCAGGTGGATTTTGCCAACCA
  CCTGCGCAAGCGCCTGGAGTCCCACCCTGCCTCTGAAGCCAGGTGTTGAAGACCAGCCTG
  CTGTTCCCAACTGTGCCCAGCTGCACTGGTACACACGCTCATCAGGAGAATCCCTACTGG
  AAGCCTGCAAGTCTAAGATCTCCATCTGGTGACAGTGGGATGGGTGGGGTTCGTGTTTAG
  AGTATGACACTAGGATTCAGATTGGTGAAAGTTTTTAGTACCAAGAAAACAGGGATGAGG
  CTCTTGGATTAAAAGGTAACTTCATTCACTGATTAGCTATGACATGAGGGTTCAGGCCCC
  TAAAATAATTGTAAAACTTTTTTTCTGGGCCCTTATGTACCCACCTAAAACCATCTTTAA
  AATGCTAGTGGCTGATATGGGTGTGGGGGATGCTAACCACAGGGCCTGAGAAGTCTTGCT
  TTATGGGCTCAAGAATGCCATGCGCTGGCAGTACATGTGCACAAAGCAGAATCTCAGAGG
  GTCTCCTGCAGCCCTCTGCTCCTCCCGGCCGCTGCACAGCAACACCACAGAACAAGCAGC
  ACCCCACAGTGGGTGCCTTCCAGAAATATAGTCCAAGCTTTCTCTGTGGAAAAAGACAAA
  ACTCATTAGTAGACATGTTTCCCTATTGCTTTCATAGGCACCAGTCAGAATAAAGAATCA
  TAATTCACACAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001007243
• ORF Size: 804 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001007243.1, NP_001007244.1
• RefSeq Size: 2641
• RefSeq ORF: 804
• Locus ID: 6770
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses alternate, in-frame splice sites in the coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.