GCN2 (EIF2AK4) (NM_001013703) Human Untagged Clone

CAT#: SC301871

EIF2AK4 (untagged)-Human eukaryotic translation initiation factor 2 alpha kinase 4 (EIF2AK4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EIF2AK4
• Synonyms: GCN2; PVOD2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001013703 edited
  GGCGCAGCGCTGCCATGGCTGGGGGCCGTGGGGCCCCCGGGCGCGGCCGGGACGAGCCTC
  CGGAGAGCTACCCGCAACGACAGGACCACGAGCTACAGGCCCTGGAGGCCATCTACGGCG
  CGGACTTCCAAGACCTGCGGCCGGACGCTTGCGGACCGGTCAAAGAGCCCCCTGAAATCA
  ATTTAGTTTTGTACCCTCAAGGCCTAACTGGTGAAGAAGTATATGTAAAAGTGGATTTGA
  GGGTTAAATGCCCACCTACCTATCCAGATGTAGTTCCTGAAATAGAGTTAAAAAATGCCA
  AAGGTCTATCAAATGAAAGTGTCAATTTGTTAAAATCTCGCCTAGAAGAACTGGCCAAGA
  AACACTGTGGGGAGGTGATGATCTTTGAACTGGCTTACCACGTGCAGTCATTTCTCAGCG
  AGCATAACAAGCCCCCTCCCAAGTCTTTTCATGAAGAAATGCTGGAAAGGCGGGCTCAGG
  AGGAGCAGCAGAGGCTGTTGGAGGCCAAGCGGAAAGAAGAGCAGGAGCAACGTGAAATCC
  TGCATGAGATTCAGAGAAGGAAAGAAGAGATAAAAGAAGAGAAAAAAAGGAAAGAAATGG
  CTAAGCAGGAACGTTTGGAAATTGCTAGTTTGTCAAACCAAGATCATACCTCTAAGAAGG
  ACCCAGGAGGACACAGAACGGCTGCCATTCTACATGGAGGCTCTCCTGACTTTGTAGGAA
  ATGGTAAACATCGGGCAAACTCCTCAGGAAGGTCTAGGCGAGAACGTCAGTATTCTGTAT
  GTAATAGTGAAGATTCTCCTGGCTCTTGTGAAATTCTGTATTTCAATATGGGGAGTCCTG
  ATCAGCTCATGGTGCACAAAGGGAAATGTATTGGCAGTGATGAACAACTTGGAAAATTAG
  TCTACAATGCTTTGGAAACAGCCACTGGTGGCTTTGTCTTGTTGTATGAGTGGGTCCTTC
  AGTGGCAGAAAAAAATGGGTCCATTCCTTACCAGTCAAGAAAAAGAGAAGATTGATAAGT
  GCAAAAAGCAGATTCAAGGAACAGAAACAGAATTCAACTCACTGGTAAAATTGAGCCATC
  CAAATGTAGTACGCTACCTTGCAATGAATCTCAAAGAGCAAGACGACTCCATCGTGGTGG
  ACATTTTAGTGGAGCACATTAGTGGGGTCTCTCTTGCTGCACACCTGAGCCACTCAGGCC
  CCATCCCTGTGCATCAGCTTCGCAGGTACACAGCTCAGCTCCTGTCAGGCCTTGATTATC
  TGCACAGCAATTCTGTGGTGCATAAGGTCCTGAGTGCATCTAATGTCTTGGTGGATGCAG
  AAGGCACCGTCAAGATTACGGACTATAGCATTTCTAAGCGCCTCGCAGACATTTGCAAGG
  AGGATGTGTTTGAGCAAACCCGAGTTCGTTTTAGTGACAATGCTCTGCCTTATAAAACGG
  GGAAGAAAGGAGATGTTTGGCGTCTTGGCCTTCTGCTGCTGTCCCTCAGCCAAGGACAGG
  AATGTGGAGAGTACCCTGTGACCATCCCTAGTGACTTACCAGCTGACTTTCAAGATTTTC
  TAAAGAAATGTGTGTGCTTGGATGACAAGGAAAGATGGAGTCCCCAGCAGTTGTTGAAAC
  ACAGCTTTATAAATCCCCAGCCAAAAATGCCTCTAGTGGAACAAAGTCCTGAAGATTCTG
  AAGGACAAGATTATGTTGAGACTGTTATTCCTAGCAACCGGCTACCCAGTGCTGCCTTCT
  TTAGTGAGACACAGAGACAGTTTTCCCGATACTTCATTGAGTTTGAAGAATTACAACTTC
  TTGGTAAAGGAGCTTTTGGAGCTGTCATCAAGGTGCAGAACAAGTTGGACGGCTGCTGCT
  ACGCAGTGAAGCGCATCCCCATCAACCCGGCCAGCCGGCAGTTCCGCAGGATCAAGGGCG
  AAGTGACACTGCTGTCACGGCTGCACCATGAGAACATTGTGCGCTACTACAACGCCTGGA
  TCGAGCGGCACGAGCGGCCGGCGGGACCGGGGACGCCGCCCCCGGACTCCGGGCCCCTGG
  CCAAGGATGACCGAGCTGCACGCGGGCAGCCGGCGAGCGACACAGACGGCCTGGACAGCG
  TAGAGGCCGCCGCGCCGCCACCCATCCTCAGCAGCTCGGTGGAGTGGAGCACTTCGGGCG
  AGCGCTCGGCCAGTGCCCGTTTCCCCGCCACCGGCCCGGGCTCCAGCGATGACGAGGACG
  ACGACGAGGACGAGCACGGTGGCGTCTTCTCCCAGTCCTTCCTGCCTGCTTCAGATTCTG
  AAAGTGATATTATCTTTGACAATGAAGATGAGAACAGTAAAAGTCAGAATCAGGATGAAG
  ATTGCAATGAAAAGAATGGCTGCCATGAAAGTGAGCCATCAGTGACGACTGAGGCTGTGC
  ACTACCTATACATCCAGATGGAGTACTGTGAGAAGAGCACTTTACGAGACACCATTGACC
  AGGGACTGTATCGAGACACCGTCAGACTCTGGAGGCTTTTTCGAGAGATTCTGGATGGAT
  TAGCTTATATCCATGAGAAAGGAATGATTCACCGGGATTTGAAGCCTGTCAACATTTTTT
  TGGATTCTGATGACCATGTGAAAATAGGTGATTTTGGTTTGGCGACAGACCATCTAGCCT
  TTTCTGCTGACAGCAAACAAGACGATCAGACAGGAGACTTGATTAAGTCAGACCCTTCAG
  GTCACTTAACTGGGATGGTTGGCACTGCTCTCTATGTAAGCCCAGAGGTCCAAGGAAGCA
  CCAAATCTGCATACAACCAGAAAGTGGATCTCTTCAGCCTGGGAATTATCTTCTTTGAGA
  TGTCCTATCACCCCATGGTCACGGCTTCAGAAAGGATCTTTGTTCTCAACCAACTCAGAG
  ATCCCACTTCGCCTAAGTTTCCAGAAGACTTTGACGATGGAGAGCATGCAAAGCAGAAAT
  CAGTCATCTCCTGGCTGTTGAACCACGATCCAGCAAAACGGCCCACAGCCACAGAACTGC
  TCAAGAGTGAGCTGCTGCCCCCACCCCAGATGGAGGAGTCAGAGCTGCATGAAGTGCTGC
  ACCACACGCTGACCAACGTGGATGGGAAGGCCTACCGCACCATGATGGCCCAGATCTTCT
  CGCAGCGCATCTCCCCTGCCATCGATTACACCTATGACAGCGACATACTGAAGGGCAACT
  TCTCAATCCGTACAGCCAAGATGCAGCAGCATGTGTGTGAAACCATCATCCGCATCTTTA
  AAAGACATGGAGCTGTTCAGTTGTGTACTCCACTACTGCTTCCCCGAAACAGACAAATAT
  ATGAGCACAACGAAGCTGCCCTATTCATGGACCACAGCGGGATGCTGGTGATGCTTCCTT
  TTGACCTGCGGATCCCTTTTGCAAGATATGTGGCAAGAAATAATATATTGAATTTAAAAC
  GATACTGCATAGAACGTGTGTTCAGGCCGCGCAAGTTAGATCGATTTCATCCCAAAGAAC
  TTCTGGAGTGTGCATTTGATATTGTCACTTCTACCACCAACAGCTTTCTGCCCACTGCTG
  AAATTATCTACACTATCTATGAAATCATCCAAGAGTTTCCAGCACTTCAGGAAAGAAATT
  ACAGTATTTATTTGAACCATACCATGTTATTGAAAGCAATACTCTTACACTGTGGGATCC
  CAGAAGATAAACTCAGTCAAGTCTACATTATTCTGTATGATGCTGTGACAGAGAAGCTGA
  CGAGGAGAGAAGTGGAAGCTAAATTTTGTAATCTGTCTTTGTCTTCTAATAGTCTGTGTC
  GACTCTACAAGTTTATTGAACAGAAGGGAGATTTGCAAGATCTTATGCCAACAATAAATT
  CATTAATAAAACAGAAAACAGGTATTGCACAGTTGGTGAAGTATGGCTTAAAAGACCTAG
  AGGAGGTTGTTGGACTGTTGAAGAAACTCGGCATCAAGTTACAGGTCTTGATCAATTTGG
  GCTTGGTTTACAAGGTGCAGCAGCACAATGGAATCATCTTCCAGTTTGTGGCTTTCATCA
  AACGAAGGCAAAGGGCTGTACCTGAAATCCTCGCAGCTGGAGGCAGATATGACCTGCTGA
  TTCCCCAGTTTAGAGGGCCACAAGCTCTGGGGCCAGTTCCCACTGCCATTGGGGTCAGCA
  TAGCTATAGACAAGATATCTGCTGCTGTCCTCAACATGGAGGAATCTGTTACAATAAGCT
  CTTGTGACCTCCTGGTTGTAAGTGTTGGCCAGATGTCTATGTCCAGGGCCATCAACCTAA
  CCCAGAAACTCTGGACAGCAGGCATCACAGCAGAAATCATGTACGACTGGTCACAGTCCC
  AAGAGGAATTACAAGAGTACTGCAGACATCATGAAATCACCTATGTGGCCCTTGTCTCGG
  ATAAAGAAGGAAGCCATGTCAAGGTTAAGTCTTTCGAGAAGGAAAGGCAGACAGAGAAGC
  GTGTGCTGGAGACTGAACTTGTGGACCATGTACTGCAGAAACTGAGGACTAAAGTCACTG
  ATGAAAGGAATGGCAGAGAAGCTTCCGATAATCTTGCAGTGCAAAATCTGAAGGGGTCAT
  TTTCTAATGCTTCAGGTTTGTTTGAAATCCATGGAGCAACAGTGGTTCCCATTGTGAGTG
  TGCTAGCCCCGGAGAAGCTGTCAGCCAGCACTAGGAGGCGCTATGAAACTCAGGTACAAA
  CTCGACTTCAGACCTCCCTTGCCAACTTACATCAGAAAAGCAGTGAAATTGAAATTCTGG
  CTGTGGATCTACCCAAAGAAACAATATTACAGTTTTTATCATTAGAGTGGGATGCTGATG
  AACAGGCATTTAACACAACTGTGAAGCAGCTGCTGTCACGCCTGCCAAAGCAAAGATACC
  TCAAATTAGTCTGTGATGAAATTTATAACATCAAAGTAGAAAAAAAGGTGTCTGTGCTAT
  TTCTGTACAGCTATAGAGATGACTACTACAGAATCTTATTTTAACCCTGAAGAACTGTCA
  TTAACCTCATTCAAACAGACAGAGGCTTATACTGGAATAATGGAATGTTGTACATTCATC
  ATAATTTAAAATTAAATTCTAAGAAGAGGCTGGGTGCAGTGGCTCACACCTTTAATCCCA
  GCACTTTGGGAAGCCAAGGCAGGAAGACTGCTTGAAACCAGGAGTTTGAGACCAGCCTGA
  GCAACAAAGCAAGACCCCATCTCTATAAAAACTAAAAAAATTAGTTGGGCATGGTGGCAC
  ATGCCTGTAGTCCCAGCTACTCCAGAGGCTGAGATGGATCATCTGAGCCTCAGGAGGTTG
  AGGCTGCAGTGAGCTGTGACTGCGCCACTGCACTCCAGTCTGGGACAACAGAGCAAGACC
  CTGTCTTAAAAAAAAAAAGAAAAAAAAATTTTTTTTCTAAGAAGCTGTCCTACAAAGTTG
  AGCTTTGTTAGTTTTTCATGTGTAATATATTATAAATTTATCTTTTGGGATATAATAAAT
  GCTTTCATATAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001013703 unedited
  AGTTCNCATTTGTATACCACTCATATAGGCGGCCGCGNAATTCGCACGAGGCGCAGCGCT
  GCCATGGCTGGGGGCCGTGGGGCCCCCGGGCGCGGCCGGGACGAGCCTCCGGAGAGCTAC
  CCGCAACGACAGGACCACGAGCTACAGGCCCTGGAGGCCATCTACGGCGCGGACTTCCAA
  GACCTGCGGCCGGACGCTTGCGGACCGGTCAAAGAGCCCCCTGAAATCAATTTAGTTTTG
  TACCCTCAAGGCCTAACTGGTGAAGAAGTATATGTAAAAGTGGATTTGAGGGTTAAATGC
  CCACCTACCTATCCAGATGTAGTTCCTGAAATAGAGTTAAAAAATGCCAAAGGTCTATCA
  AATGAAAGTGTCAATTTGTTAAAATCTCGCCTAGAAGAACTGGCCAAGAAACACTGTGGG
  GAGGTGATGATCTTTGAACTGGCTTACCACGTGCAGTCATTTCTCAGCGAGCATAACAAG
  CCCCCTCCCAAGTCTTTTCATGAAGAAATGCTGGAAAGGCGGGCTCAGGAGGAGCAGCAG
  AGGCTGTTGGAGGCCAAGCGGANAGAAGAGCAGGAGCAACGTGAAATCCTGCATGAGATT
  CAGAGAAGGAAAGAAGAAGATAAAGAAGAGAANAAAAGGAAGAAATGGCTAAGCAAGAAC
  GTTTGAAAATTGCTAGTTTGTCAAACCAAGATCATACCTCTAAGAAGGACCCAGNAGGAC
  ACAGAACGGCTGCCAATCTACATGGAAGCTCTCCTGACCTTGTAGGAAATGGTAAACATC
  GGGGCANAACTCTCAGGAAAGTCCTAGCCGAGAACGTCAGTAATCTGTAATGTAAAGTGA
  AAGATNCTCCTGCCTCTTGGGAAAATCCTGTTTTTAATATGGGGAGTCCCTGATTAGCTC
  ATGGGTGCCCAAAGGGAAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001013703 unedited
  NCCCCATTGGANGATGGCACTTCCCAGGNCCAGGNANGAGCACTGGNGGNAGGGGTCACA
  GGGNATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTC
  GAGTTTTTTTTTTTTTTTTTTATATGAAAGCATTTATTATATCCCAAAAGATAAATTTAT
  AATATATTACACATGAAAAACTAACAAAGCTCAACTTTGTAGGACAGCTTCTTAGAAAAA
  AAATTTTTTTTTCTTTTTTTTTTTAAGACAGGGTCTTGCTCTGTTGTCCCAGACTGGAGT
  GCAGTGGCGCAGTCACAGCTCACTGCAGCCTCAACCTCCTGAGGCTCAGATGATCCATCT
  CAGCCTCTGGAGTAGCTGGGACTACAGGCATGTGCCACCATGCCCAACTAATTTTTTTAG
  TTTTTATAGAGATGGGGTCTTGCTTTGTTGCTCAGGCTGGTCTCAAACTCCTGGTTTCAA
  GCAGTCTTCCTGCCTTGGCTTCCCAAAGTGCTGGGATTAAAGGTGTGAGCCACTGCACCC
  AGCCTCTTCTTAGAATTTAATTTTAAATTATGATGAATGTACAACATTCCATTATTCCAG
  TATAAGCCTCTGTCTGTTTGAATGAGGTTAATGACAGTTCTTCAGGGTTAAAATAAGATT
  CTGTAGTAGTCATCTCTATAGCTGTACAGAAATAGCACAGACACCTTTTTTTCTACTTTG
  ATGTTATAAATTTCATCACAGACTAATTTGAGGTATCTTTGCTTTGGCAGGCGTGACAGC
  AGCTGCTTCACAGTTGTGTTAAATGCCTGTTCATCAGCATCCCACTCTAATGATAAAAAC
  TGTTATATTGGTTTCTTTGGGGTAGATCCACAGCCAGAATTTCAAATTCACTGCTTTTCT
  GAAGTAAGTTTGCAAAGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001013703
• ORF Size: 4950 bp
• Insert Size: 5500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_001013703.2, NP_001013725.2
• RefSeq Size: 5532
• RefSeq ORF: 4950
• Locus ID: 440275
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]