PON2 (NM_001018161) Human Untagged Clone

CAT#: SC302202

PON2 (untagged)-Human paraoxonase 2 (PON2), transcript variant 2


  "NM_001018161" in other vectors (4)

Reconstitution Protocol

USD 580.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PON2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001018161 edited
GTAAGTTTCTCACTGGAATAGCGAGTGAGAAATGTGTTTGAAGACTAGGGAAACGAGAAG
GTATGCGGGCTGCTAGAGGGTTTCGGGTGGGTTGTTTGAAAAAGGAAGTGAAGGAATTCA
AAGTTTCACATCATGAGCCTAATGTAAGGCGTGTCCGGGCCGTCCCGAAGGTATCTGGGG
AAATAGGTTTGTGAGGACAAAGACCAGGGCCAGGCCCAGGGCGGAGCCTCCGCGGCCCCG
ACGCAGGGACTCGGCCTAGGCGGAGGACGGGGCGGAGCGCGGCCGGCACCATCGAGCCGG
GAAGATGGCACCGCCCACGGAGCTGCTGGCCAGGCCGGAGCGAGGCAGCGCGCCCGGCTC
CCGCGCCATGGGGCGGCTGGTGGCTGTGGGCTTGCTGGGGATCGCGCTGGCGCTCCTGGG
CGAGAGGCTTCTGGCACTCAGAAATCGACTTAAAGCCTCCAGAGAAGTAGAATCTGTAGA
CCTTCCACACTGCCACCTGATTAAAGGAATTGAAGCTGGCTCTGAAGATATTGACATACT
TCCCAATGGTCTGGCTTTTTTTAGTGTGGGTCTAAAATTCCCAGGACTCCACAGCTTTGC
ACCAGATAAGCCTGGAGGAATACTAATGATGGATCTAAAAGAAGAAAAACCAAGGGCACG
GGAATTAAGAATCAGTCGTGGGTTTGATTTGGCCTCATTCAATCCACATGGCATCAGCAC
TTTCATAGACAACGAATTCAAGAATACAGTGGAAATTTTTAAATTTGAAGAAGCAGAAAA
TTCTCTGTTGCATCTGAAAACAGTCAAACATGAGCTTCTTCCAAGTGTGAATGACATCAC
AGCTGTTGGACCGGCACATTTCTATGCCACAAATGACCACTACTTCTCTGATCCTTTCTT
AAAGTATTTAGAAACATACTTGAACTTACACTGGGCAAATGTTGTTTACTACAGTCCAAA
TGAAGTTAAAGTGGTAGCAGAAGGATTTGATTCAGCAAATGGGATCAATATTTCACCTGA
TGATAAGTATATCTATGTTGCTGACATATTGGCTCATGAAATTCATGTTTTGGAAAAACA
CACTAATATGAATTTAACTCAGTTGAAGGTACTTGAGCTGGATACACTGGTGGATAATTT
ATCTATTGATCCTTCCTCGGGGGACATCTGGGTAGGCTGTCATCCTAATGGCCAGAAGCT
CTTCGTGTATGACCCGAACAATCCTCCCTCGTCAGAGGTTCTCCGCATCCAGAACATTCT
ATCTGAGAAGCCTACAGTGACTACAGTTTATGCCAACAATGGGTCTGTTCTCCAAGGAAG
TTCTGTAGCCTCAGTGTATGATGGGAAGCTGCTCATAGGCACTTTATACCACAGAGCCTT
GTATTGTGAACTCTAAATTGTACTTTTGGCATGAAAGTGCGATAACTTAACAATTAATTT
TCTATGAATTGCTAATTCTGAGGGAATTTAACCAGCAACATTGACCCAGAAATGTATGGC
ATGTGTAGTTAATTTTATTCCAGTAAGGAACGGCCCTTTTAGTTCTTAGAGCACTTTTAA
CAAAAAAGGAAAATGAACAGGTTCTTTAAAATGCCAAGCAAGGGACAGAAAAGAAAGCTG
CTTTCGAATAAAGTGAATACATTTTGCACAAAGTAAGCCTCACCTTTGCCTTCCAACTGC
CAGAACATGGATTCCACTGAAATAGAGTGAATTATATTTCCTTAAAATGTGAGTGACCTC
ACTTCTGGCACTGTGACTACTATGGCTGTTTAGAACTACTGATAACGTATTTTGATGTTT
TGTACTTACATCTTTGTTTACCATTAAAAAGTTGGAGTTATATTAAAGACTAACTAAAAT
CCCAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_001018161
Insert Size 1900 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001018161.1.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001018161.1, NP_001018171.1
RefSeq Size 1633 bp
RefSeq ORF 1029 bp
Locus ID 5445
Cytogenetics 7q21.3
Protein Families Druggable Genome
Protein Pathways Metabolic pathways
Gene Summary 'This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) uses an alternate, in-frame splice site in the coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.

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