BMAL1 (ARNTL) (NM_001030272) Human Untagged Clone

CAT#: SC302507

ARNTL (untagged)-Human aryl hydrocarbon receptor nuclear translocator-like (ARNTL), transcript variant 2


  "NM_001030272" in other vectors (4)

Reconstitution Protocol

USD 760.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ARNTL
Synonyms bHLHe5; BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for SC322615 TTAGGGAAGGCAGAAAGTAGGTCAGGGACGGAGGTGCCTGTTTACCCGCGCCGGACTCAC
CGCCGCCGCCGCCGCGGGATCCGAGTGCGGGCGCGGGCGCGGGCGCTCCCGGCGAGCCAC
GGTGGTGCTGGCTAGAGTGTATACGTTTGGACCCAAGCTTAACTTTTCCAATGTGGAATC
CTGGGCCTTCATTGGTTCCGATGTCATAGGAATCTACGCTAGAGGGCTTCCTGTGTGCCG
GGCACTGTGGTTTTTGGAAGAAGCTGACCGCCTGAAAAGAAATTATAAAACATGAAAATC
GCTTTGAGGTGACCAAGTCCAGAGGCCCCTAACTCCTCCCAAGCTGGATCTGGGGTGTAA
GAACTGTGACTTCAGATCATCCAATGGCAGACCAGAGAATGGACATTTCTTCAACCATCA
GTGATTTCATGTCCCCGGGCCCCACCGACCTGCTTTCCAGCTCTCTTGGTACCAGTGGTG
TGGATTGCAACCGCAAACGGAAAGGCAGCTCCACTGACTACCAAGAAAGCATGGACACAG
ACAAAGATGACCCTCATGGAAGGTTAGAATATACAGAACACCAAGGAAGGATAAAAAATG
CAAGGGAAGCTCACAGTCAGATTGAAAAGCGGCGTCGGGATAAAATGAACAGTTTTATAG
ATGAATTGGCTTCTTTGGTACCAACATGCAACGCAATGTCCAGGAAATTAGATAAACTTA
CTGTGCTAAGGATGGCTGTTCAGCACATGAAAACATTAAGAGGTGCCACCAATCCATACA
CAGAAGCAAACTACAAACCAACTTTTCTATCAGACGATGAATTGAAACACCTCATTCTCA
GGGCAGCAGATGGATTTTTGTTTGTCGTAGGATGTGACCGAGGGAAGATACTCTTTGTCT
CAGAGTCTGTCTTCAAGATCCTCAACTACAGCCAGAATGATCTGATTGGTCAGAGTTTGT
TTGACTACCTGCATCCTAAAGATATTGCCAAAGTCAAGGAGCAGCTCTCCTCCTCTGACA
CCGCACCCCGGGAGCGGCTCATAGATGCAAAAACTGGACTTCCAGTTAAAACAGATATAA
CCCCTGGGCCATCTCGATTATGTTCTGGAGCACGACGTTCTTTCTTCTGTAGGATGAAGT
GTAACAGGCCTTCAGTAAAGGTTGAAGACAAGGACTTCCCCTCTACCTGCTCAAAGAAAA
AAGATCGAAAAAGCTTCTGCACAATCCACAGCACAGGCTATTTGAAAAGCTGGCCACCCA
CAAAGATGGGGCTGGATGAAGACAACGAACCAGACAATGAGGGGTGTAACCTCAGCTGCC
TCGTCGCAATTGGACGACTGCATTCTCATGTAGTTCCACAACCAGTGAACGGGGAAATCA
GGGTGAAATCTATGGAATATGTTTCTCGGCACGCGATAGATGGAAAGTTTGTTTTTGTAG
ACCAGAGGGCAACAGCTATTTTGGCATATTTACCACAAGAACTTCTAGGCACATCGTGTT
ATGAATATTTTCACCAAGATGACATAGGACATCTTGCAGAATGTCATAGGCAAGTTTTAC
AGACGAGAGAAAAAATTACAACTAATTGCTATAAATTTAAAATCAAAGATGGTTCTTTTA
TCACACTACGGAGTCGATGGTTCAGTTTCATGAACCCTTGGACCAAGGAAGTAGAATATA
TTGTCTCAACTAACACTGTTGTTTTAGCCAACGTCCTGGAAGGCGGGGACCCAACCTTCC
CACAGCTCACAGCATCCCCCCACAGCATGGACAGCATGCTGCCCTCTGGAGAAGGTGGCC
CAAAGAGGACCCACCCCACTGTTCCAGGGATTCCAGGGGGAACCCGGGCTGGGGCAGGAA
AAATAGGCCGAATGATTGCTGAGGAAATCATGGAAATCCACAGGATAAGAGGGTCATCGC
CTTCTAGCTGTGGCTCCAGCCCATTGAACATCACGAGTACGCCTCCCCCTGATGCCTCTT
CTCCAGGAGGCAAGAAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTAC
TATCAGGCCAGGCTCAGGAGAACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTG
GTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAAGTAGTCCCA
GTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGG
GTGGCCCTGTTGACTTTAGTGACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGG
CAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTACAGTCTGTGAAGCTTACTG
GATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGAT
ACAAGTCAATCTTACTATATGTAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTT
TCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCATTAATTGTATATTTTGGAT
TCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATAT
GCAAATGGTCATTTCAGATGTATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGAT
ATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCTTGTAAGAATCCTTTACTA
TAAATATGGGTTAAAGTATAATGTACTAGACAGTTAAATATTTTTAATAAATGTTTCCCT
TGTTCTATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAA
Restriction Sites Please inquire     
ACCN NM_001030272
Insert Size 2800 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001030272.1, NP_001025443.1
RefSeq Size 2757 bp
RefSeq ORF 1878 bp
Locus ID 406
Cytogenetics 11p15.3
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Circadian rhythm - mammal
Gene Summary 'The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]'
Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 4. The resulting isoform (a) is 1 aa shorter compared to isoform c. Variants 1, 2, 10, and 11 all encode isoform a.

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