LLGL2 (NM_001031803) Human Untagged Clone

CAT#: SC302597

LLGL2 (untagged)-Human lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LLGL2
• Synonyms: HGL; Hugl-2; LGL2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene SC302597 ORF sequence for NM_001031803, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGCGGTTCCTGAGGCCAGGGCATGACCCTGTGCGGGAGAGGCTCAAGCGGGACCTGTTCCAGTTTA
  ACAAGACGGTGGAGCATGGCTTCCCGCACCAGCCCAGCGCCCTCGGCTACAGCCCGTCCCTGCGCATCCT
  GGCCATCGGCACCCGTTCTGGAGCCATCAAGCTCTACGGAGCCCCAGGCGTGGAGTTCATGGGGCTGCAC
  CAGGAGAACAACGCTGTGACGCAGATCCACCTCCTGCCCGGCCAGTGCCAGCTGGTCACCCTGCTGGATG
  ACAACAGCCTGCACCTTTGGAGCCTGAAGGTCAAGGGCGGGGCATCGGAGCTGCAGGAGGATGAGAGCTT
  CACACTGCGTGGACCCCCAGGGGCTGCCCCCAGTGCCACACAGATCACCGTGGTCCTGCCACATTCCTCC
  TGCGAGCTGCTCTACCTGGGCACCGAGAGTGGCAACGTGTTTGTGGTGCAGCTGCCAGCTTTTCGTGCGC
  TGGAGGACCGGACCATCAGCTCGGACGCGGTGCTGCAGCGGTTGCCAGAGGAGGCCCGCCACCGGCGTGT
  GTTCGAGATGGTGGAGGCACTGCAGGAGCACCCTCGAGACCCCAACCAGATCCTGATCGGCTACAGCCGA
  GGCCTCGTTGTCATCTGGGACCTACAGGGCAGCCGCGTGCTCTACCACTTCCTCAGCAGCCAGCAACTGG
  AGAACATCTGGTGGCAGCGGGACGGCCGCCTGCTCGTCAGCTGTCACTCTGACGGCAGCTACTGCCAGTG
  GCCCGTGTCCAGCGAAGCCCAGCAACCAGAGCCCCTCCGCAGCCTCGTGCCTTACGGTCCCTTTCCTTGC
  AAAGCGATTACCAGAATCCTCTGGCTGACCACTAGGCAGGGGTTGCCCTTCACCATCTTCCAGGGTGGCA
  TGCCACGGGCCAGCTACGGGGACCGCCACTGCATCTCAGTGATCCACGATGGCCAGCAGACGGCCTTCGA
  CTTCACCTCCCGTGTCATCGGCTTCACTGTCCTCACAGAGGCAGACCCTGCAGCCACCTTTGACGACCCC
  TATGCCCTGGTGGTGCTGGCTGAGGAGGAGCTGGTGGTGATTGACCTGCAGACAGCAGGCTGGCCACCGG
  TCCAGCTGCCCTACCTGGCTTCTCTGCACTGTTCCGCCATCACCTGCTCTCACCACGTCTCCAACATCCC
  GCTGAAGCTGTGGGAGCGGATCATTGCCGCCGGCAGCCGGCAGAACGCACACTTCTCCACCATGGAGTGG
  CCAATTGATGGTGGCACCAGCCTGACCCCAGCCCCACCCCAGAGGGACCTGCTGCTCACAGGGCACGAGG
  ACGGCACGGTGCGGTTCTGGGATGCCTCGGGTGTCTGCCTGCGGCTGCTCTACAAACTCAGCACTGTGCG
  CGTGTTCCTCACCGACACGGACCCCAACGAGAACCTCAGTGCCCAGGGCGAGGACGAGTGGCCCCCACTC
  CGCAAGGTGGGCTCCTTTGACCCCTACAGTGATGACCCCCGGCTGGGCATCCAGAAGATCTTCCTCTGCA
  AGTACAGCGGCTACCTGGCTGTGGCAGGCACGGCAGGGCAGGTGCTGGTACTGGAACTGAATGACGAGGC
  AGCGGAGCAGGCTGTGGAGCAGGTGGAGGCCGACCTGCTGCAGGACCAAGAGGGCTACCGCTGGAAGGGG
  CACGAGCGCCTGGCAGCCCGCTCAGGGCCCGTGCGCTTTGAGCCTGGCTTTCAGCCCTTCGTGTTGGTGC
  AGTGTCAGCCCCCGGCTGTGGTCACCTCCTTGGCCCTGCACTCTGAGTGGCGGCTCGTGGCCTTCGGCAC
  CAGCCATGGCTTTGGCCTCTTTGACCACCAGCAGCGGCGGCAGGTCTTTGTTAAGTGCACACTGCACCCC
  AGTGACCAGCTGGCCTTGGAGGGCCCACTCTCCCGCGTCAAGTCCCTCAAGAAGTCCTTGCGTCAGTCAT
  TCCGCCGGATGCGTCGGAGCCGGGTGTCCAGCCGGAAGCGGCACCCAGCTGGCCCCCCAGGAGAGGCACA
  GGAGGGGAGTGCCAAGGCTGAGCGGCCAGGCCTCCAGAACATGGAGCTGGCGCCTGTGCAGCGCAAGATC
  GAGGCTCGCTCGGCAGAGGACTCCTTCACAGGCTTCGTCCGGACCCTGTACTTTGCTGACACCTACCTGA
  AGGACAGCTCCCGGCACTGCCCCTCGCTGTGGGCTGGCACCAATGGGGGCACCATCTATGCCTTCTCCCT
  GCGTGTGCCTCCCGCCGAGCGGAGAATGGATGAGTCTGTGCGGGCAGAGCAGGCCAAGGAGATCCAGCTG
  ATGCACCGGGCGCCGGTGGTGGGCATCCTGGTGCTCGACGGACACAGCGTACCCCTTCCTGAGCCCCTCG
  AAGTGGCCCATGATCTGTCGAAGAGCCCTGACATGCAGGGAAGCCACCAGCTGCTCGTCGTATCAGAGGA
  GCAGTTCAAGGTGTTCACGCTGCCCAAGGTGAGTGCCAAGCTGAAGTTGAAGCTGACGGCCCTGGAGGGC
  TCAAGAGTGCGGCGGGTCAGCGTGGCCCACTTCGGCAGTCGTCGAGCCGAGGACTACGGGGAGCACCACC
  TGGCAGTCCTTACCAACCTGGGCGACATCCAGGTGGTCTCGCTGCCCCTGCTCAAGCCCCAGGTGCGCTA
  CAGCTGCATCCGCCGGGAGGACGTCAGTGGCATCGCCTCCTGCGTCTTCACCAAATATGGCCAAGGCTTC
  TACCTGATCTCACCCTCGGAGTTTGAGCGCTTCTCTCTCTCCACCAAGTGGCTGGTGGAGCCCCGGTGTC
  TGGTGGATTCAGCAGAAACCAAGAACCACCGCCCTGGTAACGGTGCGGGCCCCAAGAAGGCCCCGAGCCG
  AGCCAGGAACTCAGGGACTCAGAGTGATGGCGAGGAGAAGCAGCCCGGCCTGGTGATGGAGCGCGCTCTG
  CTCAGTGATGAGAGAGTCCTGAAGGAAATCCAGAGCACACTGGAGGGAGACCGCGGGAGCGGCAACTGGC
  GTTCACATCGAGCGGCCGTGGGGTGCAGCCTCAGCAATGGCGGAGCAGAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001031803
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001031803.1, NP_001026973.1
• RefSeq Size: 3590 bp
• RefSeq ORF: 3063 bp
• Locus ID: 3993
• Cytogenetics: 17q25.1
• Protein Families: Druggable Genome
• Protein Pathways: Tight junction
• Gene Summary: 'The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (c).