RSPO1 (NM_001038633) Human Untagged Clone

CAT#: SC302953

RSPO1 (untagged)-Human R-spondin homolog (Xenopus laevis) (RSPO1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RSPO1
• Synonyms: CRISTIN3; RSPO
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001038633 edited
  GTTAGCAAGAGCCGTGTGCTATCCACCCTCCCCGAGACCACCCCTCCGACCAGGGGCCTG
  GAGCTGGCGCGTGACTATGCGGCTTGGGCTGTGTGTGGTGGCCCTGGTTCTGAGCTGGAC
  GCACCTCACCATCAGCAGCCGGGGGATCAAGGGGAAAAGGCAGAGGCGGATCAGTGCCGA
  GGGGAGCCAGGCCTGTGCCAAAGGCTGTGAGCTCTGCTCTGAAGTCAACGGCTGCCTCAA
  GTGCTCACCCAAGCTGTTCATCCTGCTGGAGAGGAACGACATCCGCCAGGTGGGCGTCTG
  CTTGCCGTCCTGCCCACCTGGATACTTCGACGCCCGCAACCCCGACATGAACAAGTGCAT
  CAAATGCAAGATCGAGCACTGTGAGGCCTGCTTCAGCCATAACTTCTGCACCAAGTGTAA
  GGAGGGCTTGTACCTGCACAAGGGCCGCTGCTATCCAGCTTGTCCCGAGGGCTCCTCAGC
  TGCCAATGGCACCATGGAGTGCAGTAGTCCTGCGCAATGTGAAATGAGCGAGTGGTCTCC
  GTGGGGGCCCTGCTCCAAGAAGCAGCAGCTCTGTGGTTTCCGGAGGGGCTCCGAGGAGCG
  GACACGCAGGGTGCTACATGCCCCTGTGGGGGACCATGCTGCCTGCTCTGACACCAAGGA
  GACCCGGAGGTGCACAGTGAGGAGAGTGCCGTGTCCTGAGGGGCAGAAGAGGAGGAAGGG
  AGGCCAGGGCCGGCGGGAGAATGCCAACAGGAACCTGGCCAGGAAGGAGAGCAAGGAGGC
  GGGTGCTGGCTCTCGAAGACGCAAGGGGCAGCAACAGCAGCAGCAGCAAGGGACAGTGGG
  GCCACTCACATCTGCAGGGCCTGCCTAGGGACACTGTCCAGCCTCCAGGCCCATGCAGAA
  AGAGTTCAGTGCTACTCTGCGTGATTCAAGCTTTCCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001038633 unedited
  NGGGGAAGTTCACATTTGTATACGACTCATATAGGGCGGCCGCGATTCGCCCCANAGTGT
  TAGCAAGAGCCGTGTGCTATCCACCCTCCCCGANACCACCCCTCCGACCAGGGGCCTGGA
  GCTGGCGCGTGACTATGCGGCTTGGGCTGTGTGTGGTGGCCCTGGTTCTGAGCTGGACGC
  ACCTCACCATCAGCAGCCGGGGGATCAAGGGGAAAAGGCAGAGGCGGATCAGTGCCGAGG
  GGAGCCAGGCCTGTGCCAAAGGCTGTGAGCTCTGCTCTGAAGTCAACGGCTGCCTCAAGT
  GCTCACCCAAGCTGTTCATCCTGCTGGAGAGGAACGACATCCGCCAGGTGGGCGTCTGCT
  TGCCGTCCTGCCCACCTGGATACTTCGACGCCCGCAACCCCGACATGAACAAGTGCATCA
  AATGCAAGATCGAGCACTGTGAGGCCTGCTTCAGCCATAACTTCTGCACCAAGTGTAAGG
  AGGGCTTGTACCTGCACAAGGGCCGCTGCTATCCAGCTTGTCCCGAGGGCTCCTCAGCTG
  CCAATGGCACCATGGAGTGCAGTAGTCCTGCGCAATGTGAAATGAGCGAGTGGTCTCCGT
  GGGGGCCCTGCTCCAAGAAGCAGCAGCTCTGTGGTTTCCGGAGGGGCTCCGAGGAGCGGA
  CACGCAGGGTGCTACATGCCCCTGTGGGGGACCATGCTGCCTGCTCTGACACCAAGAACC
  CCGGAGGTGCACAGTGAGGGGAGAGTGCCGTGTCCTGAGGGGGCANAAAGGNAGGAAAAG
  GAGGGCCAGGGCCCGGNCGGGAGAATGCCAACAGGAACCTGGCCAGNNAAGANAGCAGGA
  NGGCCGNNTGCTGGCTCTCGAGAACGCAGGGGGCAGCAACAGCAGCAGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001038633 unedited
  NGGGCCCATTGGNGAATGGCACTTCCCAGGNCCAGNANGAGCCTGGGGNAGGGTCACAGG
  GNAGCCACCCGGGATCTGTTCAGGAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGT
  CAGGAAAGCTTGAATCACGCAGAGTAGCACTGAACTCTTTCTGCATGGGCCTGGAGGCTG
  GACAGTGTCCCTAGGCAGGCCCTGCAGATGTGAGTGGCCCCACTGTCCCTTGCTGCTGCT
  GCTGTTGCTGCCCCTTGCGTCTTCGAGAGCCAGCACCCGCCTCCTTGCTCTCCTTCCTGG
  CCAGGTTCCTGTTGGCATTCTCCCGCCGGCCCTGGCCTCCCTTCCTCCTCTTCTGCCCCT
  CAGGACACGGCACTCTCCTCACTGTGCACCTCCGGGTCTCCTTGGTGTCAGAGCAGGCAG
  CATGGTCCCCCACAGGGGCATGTAGCACCCTGCGTGTCCGCTCCTCGGAGCCCCTCCGGA
  AACCACAGAGCTGCTGCTTCTTGGAGCAGGGCCCCCACGGAGACCACTCGCTCATTTCAC
  ATTGCGCAGGACTACTGCACTCCATGGTGCCATTGGCAGCTGAGGAGCCCTCGGGACAAG
  CTGGATAGCAGCGGCCCTTGTGCAGGTACAAGCCCTCCTTACACTTGGTGNCAGAAGTTA
  TGGCTGAAGCAGGCCTCACAGTGCTCGATCTTGCATTTGATGCACTTGTTCATGTTTCGG
  GTTTGCGGCGGTTCGAAGTATCCCAGGTGGGCAGGACGGCAAGCAGACGCCCACCTGNNC
  GGATGTCGTTCCTCNTCCAGCAGATGAACAGCCTNGGGTGAGCACTTGAGGCAGCCGNTG
  ACTTCAGAGCAGAGCTCACAGNCTTTGGCACAGGCCTGGCTCCCCTCGGNACTGATCCGG
  CTCTGGCTTTTN
  
• Restriction Sites: Please inquire
• ACCN: NM_001038633
• ORF Size: 792 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_001038633.2, NP_001033722.1
• RefSeq Size: 2995
• RefSeq ORF: 792
• Locus ID: 284654
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Both variants 1 and 2 encode the same isoform (1).