CD30 (TNFRSF8) (NM_001243) Human Untagged Clone
CAT#: SC302996
TNFRSF8 (untagged)-Human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1
"NM_001243" in other vectors (6)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | TNFRSF8 |
Synonyms | CD30; D1S166E; Ki-1 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_001243 edited
GAGTGTGCTGGAGCCTGAAGTCCACGCGCGCGGCTGAGAACCGCCGGGACCGCACGTGGG CGCCGCGCGCTTCCCCCGCTTCCCAGGTGGGCGCCGGCCGCCAGGCCACCTCACGTCCGG CCCCGGGGATGCGCGTCCTCCTCGCCGCGCTGGGACTGCTGTTCCTGGGGGCGCTACGAG CCTTCCCACAGGATCGACCCTTCGAGGACACCTGTCATGGAAACCCCAGCCACTACTATG ACAAGGCTGTCAGGAGGTGCTGTTACCGCTGCCCCATGGGGCTGTTCCCGACACAGCAGT GCCCACAGAGGCCTACTGACTGCAGGAAGCAGTGTGAGCCTGACTACTACCTGGATGAGG CCGACCGCTGTACAGCCTGCGTGACTTGTTCTCGAGACGACCTCGTGGAGAAGACGCCGT GTGCATGGAACTCCTCCCGTGTCTGCGAATGTCGACCCGGCATGTTCTGTTCCACGTCTG CCGTCAACTCCTGTGCCCGCTGCTTCTTCCATTCTGTCTGTCCGGCAGGGATGATTGTCA AGTTCCCAGGCACGGCGCAGAAGAACACGGTCTGTGAGCCGGCTTCCCCAGGGGTCAGCC CTGCCTGTGCCAGCCCAGAGAACTGCAAGGAACCCTCCAGTGGCACCATCCCCCAGGCCA AGCCCACCCCGGTGTCCCCAGCAACCTCCAGTGCCAGCACCATGCCTGTAAGAGGGGGCA CCCGCCTCGCCCAGGAAGCTGCTTCTAAACTGACGAGGGCTCCCGACTCTCCCTCCTCTG TGGGAAGGCCTAGTTCAGATCCAGGTCTGTCCCCAACACAGCCATGCCCAGAGGGGTCTG GTGATTGCAGAAAGCAGTGTGAGCCCGACTACTACCTGGACGAGGCCGGCCGCTGCACGG CCTGCGTGAGCTGTTCTCGAGATGACCTTGTGGAGAAGACGCCATGTGCATGGAACTCCT CCCGCACCTGCGAATGTCGACCTGGCATGATCTGTGCCACATCAGCCACCAACTCCTGTG CCCGCTGTGTCCCCTACCCAATCTGTGCAGCAGAGACGGTCACCAAGCCCCAGGATATGG CTGAGAAGGACACCACCTTTGAGGCGCCACCCCTGGGGACCCAGCCGGACTGCAACCCCA CCCCAGAGAATGGCGAGGCGCCTGCCAGCACCAGCCCCACTCAGAGCTTGCTGGTGGACT CCCAGGCCAGTAAGACGCTGCCCATCCCAACCAGCGCTCCCGTCGCTCTCTCCTCCACGG GGAAGCCCGTTCTGGATGCAGGGCCAGTGCTCTTCTGGGTGATCCTGGTGTTGGTTGTGG TGGTCGGCTCCAGCGCCTTCCTCCTGTGCCACCGGAGGGCCTGCAGGAAGCGAATTCGGC AGAAGCTCCACCTGTGCTACCCGGTCCAGACCTCCCAGCCCAAGCTAGAGCTTGTGGATT CCAGACCCAGGAGGAGCTCAACGCAGCTGAGGAGTGGTGCGTCGGTGACAGAACCCGTCG CGGAAGAGCGAGGGTTAATGAGCCAGCCACTGATGGAGACCTGCCACAGCGTGGGGGCAG CCTACCTGGAGAGCCTGCCGCTGCAGGATGCCAGCCCGGCCGGGGGCCCCTCGTCCCCCA GGGACCTTCCTGAGCCCCGGGTGTCCACGGAGCACACCAATAACAAGATTGAGAAAATCT ACATCATGAAGGCTGACACCGTGATCGTGGGGACCGTGAAGGCTGAGCTGCCGGAGGGCC GGGGCCTGGCGGGGCCAGCAGAGCCCGAGTTGGAGGAGGAGCTGGAGGCGGACCATACCC CCCACTACCCCGAGCAGGAGACAGAACCGCCTCTGGGCAGCTGCAGCGATGTCATGCTCT CAGTGGAAGAGGAAGGGAAAGAAGACCCCTTGCCCACAGCTGCCTCTGGAAAGTGAGGCC TGGGCTGGGCTGGGGCTAGGAGGGCAGCAGGGTGGCCTCTGGGAGGCCAGGATGGCACTG TTGGCACCGAGGTTGGGGGCAGAGGCCCATCTGGCCTGAACTGAGGCTCCAGCATCTAGT GGTGGACCGGCCGGTCACTGCAGGGGTATGGTGGTCTCTGCTTGCAT >Reverse primer walk for NM_001243 unedited
AAAGTCGGGNAGCCCTCGTCAGTTTAGAAGCAGCTTCCTGGGCGAGGCGGGTGCCCCCTC TTACAGGCATGGTGCTGGCACTGGAGGTTGCTGGGGACACCGGGGTGGGCTTGGCCTGGG GGATGGTGCCACTGGAGGGTTCCTTGCAGTTCTCTGGGCTGGCACAGGCAGGGCTGACCC CTGGGGAAGCCGGCTCACAGACCGTGTTCTTCTGCGCCGTGCCTGGGAACTTGACAATCA TCCCTGCCGGACAGACAGAATGGAAGAAGCAGCGGGCACAGGAGTTGACGGCAGACGTGG AACAGAACATGCCGGGTCGACATTCGCAGACACGGGAGGAGTTCCATGCACACGGCGTCT TCTCCACGAGGTCGTCTCGAGAACAAGTCACGCAGGCTGTACAGCGGTCGGCCTCATCCA GGTAGTAGTCAGGCTCACACTGCTTCCTGCAGTCAGTAGGCCTCTGTGGGCACTGCTGTG TCGGGAACAGCCCCATGGGGCAGCGGTAACAGCACCTCCTGACAGCCTTGTCATAGTAGT GGCTGGGGTTTCCATGACAGGTGTCCTCGAAGGGTCGATCCTGTGGGAAGGCTCGTAGCG CCCCCAGGAACAGCAGTCCCAGCGCGGCGAGGAGGACGCGCATCCCCGGNGCCGGACGTG AGGTGGCCTGGCGGCCGGCGCCCACCTGNGAAGCGGNGGAAGCGCGNCGCGCCCACGTGC GGTCCCGGGCGTTCTCAGCCGCGCGCGTGGACTTTCAGCTCCAGCACACTCAAGGGCGAA TTCTGCAGATATCGTACCAGATCTGAATTCGCGGCCGCCCTATAGTGAGTCGTATTACAN AATTTCTGACGGTCACTAAACGAGCTCT >OriGene 3' read for NM_001243 unedited
CATTGGNGAATGGCACTTNCCAGGNCCAGAAAAGCACTGGGGNAGGGTCACAGGGATGCC ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACAAGCTT GGTACCGAGCTCGGATCCACTAGTAACGGCCGCCAGTGTGCTGGAATTCGCCCTTATGCA AGCAGAGACCACCATACCCCTGCAGTGACCGGCCGGTCCACCACTAGATGCTGGAGCCTC AGTTCAGGCCAGATGGGCCTCTGCCCCCAACCTCGGTGCCAACAGTGCCATCCTGGCCTC CCAGAGGCCACCCTGCTGCCCTCCTAGCCCCAGCCCAGCCCAGGCCTCACTTTCCAGAGG CAGCTGTGGGCAAGGGGTCTTCTTTCCCTTCCTCTTCCACTGAGAGCATGACATCGCTGC AGCTGCCCAGAGGCGGTTCTGTCTCCTGCTCGGGGTAGTGGGGGGTATGGTCCGCCTCCA GCTCCTCCTCCAACTCGGGCTCTGCTGGCCCCGCCAGGCCCCGGCCCTCCGGCAGCTCAG CCTTCACGGTCCCCACGATCACGGTGTCAGCCTTCATGATGTAGATTTTCTCAATCTTGT TATTGGTGTGCTCCGTGGACACCCGGNGCTCAAGAAAGTCCCTGGGGGACGAGGGGCCCC CGGCCGGGCTGGCATCCTGCAGCGGCAGGCTCTCCAGGTAGGCTGCCCCCACGCTGTGGC AAGTCTCCATCAGTGGCTGGCTCATTAACCCTCGCTCTTCCGCGACGGGTTCTGTCACCG ACGCACCACTCCTTAGCTGCGTTTGAGCTCCTNCCTGGGTCGGGAATCCACAAGCTCCTA GCTGGGGCTGGG |
Restriction Sites | Please inquire |
ACCN | NM_001243 |
Insert Size | 2100 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substitution of 1 amino acids. |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001243.3, NP_001234.2 |
RefSeq Size | 3686 bp |
RefSeq ORF | 1788 bp |
Locus ID | 943 |
Cytogenetics | 1p36.22 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
Gene Summary | 'The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]' Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC219819 | TNFRSF8 (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 |
USD 480.00 |
|
RG219819 | TNFRSF8 (GFP-tagged) - Human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 |
USD 530.00 |
|
RC219819L1 | Lenti-ORF clone of TNFRSF8 (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 |
USD 840.00 |
|
RC219819L2 | Lenti-ORF clone of TNFRSF8 (mGFP-tagged)-Human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 |
USD 840.00 |
|
RC219819L3 | Lenti-ORF clone of TNFRSF8 (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 |
USD 840.00 |
|
RC219819L4 | Lenti-ORF clone of TNFRSF8 (mGFP-tagged)-Human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 |
USD 680.00 |
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