P cadherin (CDH3) (NM_001793) Human Untagged Clone

CAT#: SC303069

CDH3 (untagged)-Human cadherin 3, type 1, P-cadherin (placental) (CDH3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDH3
• Synonyms: CDHP; HJMD; PCAD
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001793 edited
  GGCTAGCGCGGGAGGTGGAGAAAGAGGCTTGGGCGGCCCCGCTGTAGCCGCGTGTGGGAG
  GACGCACGGGCCTGCTTCAAAGCTTTGGGATAACAGCGCCTCCGGGGGATAATGAATGCG
  GAGCCTCCGTTTTCAGTCGACTTCAGATGTGTCTCCACTTTTTTCCGCTGTAGCCGCAAG
  GCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTT
  CTCCTCTAACCCAGAACTGCGAGACAGAGGCTGAGTCCCTGTAAAGAACAGCTCCAGAAA
  AGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGGAGGGGTTCGCTGGGGCCTCAACC
  GCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCA
  CCCACCTGCGCTCACCTGGCCTCCTCCCGCTGGCTCCCGGGGGCTGCGGTGCTCAAAGGG
  GCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGCAGCTGCTTCACCCCTCTCTCTGC
  AGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCT
  GCAGTGCGCGGCCTCCGAGCCGTGCCGGGCGGTCTTCAGGGAGGCTGAAGTGACCTTGGA
  GGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTGGGGAAAGTATTCATGGGCTGCCC
  TGGGCAAGAGCCAGCTCTGTTTAGCACTGATAATGATGACTTCACTGTGCGGAATGGCGA
  GACAGTCCAGGAAAGAAGGTCACTGAAGGAAAGGAATCCATTGAAGATCTTCCCATCCAA
  ACGTATCTTACGAAGACACAAGAGAGATTGGGTGGTTGCTCCAATATCTGTCCCTGAAAA
  TGGCAAGGGTCCCTTCCCCCAGAGACTGAATCAGCTCAAGTCTAATAAAGATAGAGACAC
  CAAGATTTTCTACAGCATCACGGGGCCGGGGGCAGACAGCCCCCCTGAGGGTGTCTTCGC
  TGTAGAGAAGGAGACAGGCTGGTTGTTGTTGAATAAGCCACTGGACCGGGAGGAGATTGC
  CAAGTATGAGCTCTTTGGCCACGCTGTGTCAGAGAATGGTGCCTCAGTGGAGGACCCCAT
  GAACATCTCCATCATAGTGACCGACCAGAATGACCACAAGCCCAAGTTTACCCAGGACAC
  CTTCCGAGGGAGTGTCTTAGAGGGAGTCCTACCAGGTACTTCTGTGATGCAGATGACAGC
  CACAGATGAGGATGATGCCATCTACACCTACAATGGGGTGGTTGCTTACTCCATCCATAG
  CCAAGAACCAAAGGACCCACACGACCTCATGTTCACAATTCACCGGAGCACAGGCACCAT
  CAGCGTCATCTCCAGTGGCCTGGACCGGGAAAAAGTCCCTGAGTACACACTGACCATCCA
  GGCCACAGACATGGATGGGGACGGCTCCACCACCACGGCAGTGGCAGTAGTGGAGATCCT
  TGATGCCAATGACAATGCTCCCATGTTTGACCCCCAGAAGTACGAGGCCCATGTGCCTGA
  GAATGCAGTGGGCCATGAGGTGCAGAGGCTGACGGTCACTGATCTGGACGCCCCCAACTC
  ACCAGCGTGGCGTGCCACCTACCTTATCATGGGCGGTGACGACGGGGACCATTTTACCAT
  CACCACCCACCCTGAGAGCAACCAGGGCATCCTGACAACCAGGAAGGGTTTGGATTTTGA
  GGCCAAAAACCAGCACACCCTGTACGTTGAAGTGACCAACGAGGCCCCTTTTGTGCTGAA
  GCTCCCAACCTCCACAGCCACCATAGTGGTCCACGTGGAGGATGTGAATGAGGCACCTGT
  GTTTGTCCCACCCTCCAAAGTCGTTGAGGTCCAGGAGGGCATCCCCACTGGGGAGCCTGT
  GTGTGTCTACACTGCAGAAGACCCTGACAAGGAGAATCAAAAGATCAGCTACCGCATCCT
  GAGAGACCCAGCAGGGTGGCTAGCCATGGACCCAGACAGTGGGCAGGTCACAGCTGTGGG
  CACCCTCGACCGTGAGGATGAGCAGTTTGTGAGGAACAACATCTATGAAGTCATGGTCTT
  GGCCATGGACAATGGAAGCCCTCCCACCACTGGCACGGGAACCCTTCTGCTAACACTGAT
  TGATGTCAACGACCATGGCCCAGTCCCTGAGCCCCGTCAGATCACCATCTGCAACCAAAG
  CCCTGTGCGCCAGGTGCTGAACATCACGGACAAGGACCTGTCTCCCCACACCTCCCCTTT
  CCAGGCCCAGCTCACAGATGACTCAGACATCTACTGGACGGCAGAGGTCAACGAGGAAGG
  TGACACAGTGGTCTTGTCCCTGAAGAAGTTCCTGAAGCAGGATACATATGACGTGCACCT
  TTCTCTGTCTGACCATGGCAACAAAGAGCAGCTGACGGTGATCAGGGCCACTGTGTGCGA
  CTGCCATGGCCATGTCGAAACCTGCCCTGGACCCTGGAAAGGAGGTTTCATCCTCCCTGT
  GCTGGGGGCTGTCCTGGCTCTGCTGTTCCTCCTGCTGGTGCTGCTTTTGTTGGTGAGAAA
  GAAGCGGAAGATCAAGGAGCCCCTCCTACTCCCAGAAGATGACACCCGTGACAACGTCTT
  CTACTATGGCGAAGAGGGGGGTGGCGAAGAGGACCAGGACTATGACATCACCCAGCTCCA
  CCGAGGTCTGGAGGCCAGGCCGGAGGTGGTTCTCCGCAATGACGTGGCACCAACCATCAT
  CCCGACACCCATGTACCGTCCTAGGCCAGCCAACCCAGATGAAATCGGCAACTTTATAAT
  TGAGAACCTGAAGGCGGCTAACACAGACCCCACAGCCCCGCCCTACGACACCCTCTTGGT
  GTTCGACTATGAGGGCAGCGGCTCCGACGCCGCGTCCCTGAGCTCCCTCACCTCCTCCGC
  CTCCGACCAAGACCAAGATTACGATTATCTGAACGAGTGGGGCAGCCGCTTCAAGAAGCT
  GGCAGACATGTACGGTGGCGGGGAGGACGACTAGGCGGCCTGCCTGCAGGGCTGGGGACC
  AAACGTCAGGCCACAGAGCATCTCCAAGGGGTCTCAGTTCCCCCTTCAGCTGAGGACTTC
  GGAGCTTGTCAGGAAGTGGCCGTAGCAACTTGGCGGAGACAGGCTATGAGTCTGACGTTA
  GAGTGGTTGCTTCCTTAGCCTTTCAGGATGGAGGAATGTGGGCAGTTTGACTTCAGCACT
  GAAAACCTCTCCACCTGGGCCAGGGTTGCCTCAGAGGCCAAGTTTCCAGAAGCCTCTTAC
  CTGCCGTAAAATGCTCAACCCTGTGTCCTGGGCCTGGGCCTGCTGTGACTGACCTACAGT
  GGACTTTCTCTCTGGAATGGAACCTTCTTAGGCCTCCTGGTGCAACTTAATTTTTTTTTT
  TAATGCTATCTTCAAAACGTTAGAGAAAGTTCTTCAAAAGTGCAGCCCAGAGCTGCTGGG
  CCCACTGGCCGTCCTGCATTTCTGGTTTCCAGACCCCAATGCCTCCCATTCGGATGGATC
  TCTGCGTTTTTATACTGAGTGTGCCTAGGTTGCCCCTTATTTTTTATTTTCCCTGTTGCG
  TTGCTATAGATGAAGGGTGAGGACAATCGTGTATATGTACTAGAACTTTTTTATTAAAGA
  AACTTTTCCCAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001793 unedited
  NNAAGTTATATTTGTATACCATCATATAGGCGGCCGCATAACTTCGTATAGCATACATTA
  TACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGGCTAGC
  GCGGGAGGTGGAGAAAGAGGCTTGGGCGGCCCCGCTGTAGCCGCGTGTGGGAGGACGCAC
  GGGCCTGCTTCAAAGCTTTGGGATAACAGCGCCTCCGGGGGATAATGAATGCGGAGCCTC
  CGTTTTCAGTCGACTTCAGATGTGTCTCCACTTTTTTCCGCTGTAGCCGCAAGGCAAGGA
  AACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCT
  AACCCAGAACTGCGAGACAGAGGCTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGG
  AGAGCGCAGGAGGGCATCCGGGAGGCCAGGAGGGGTTCGCTGGGGCCTCAACCGCACCCA
  CATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCT
  GCGCTCACCTGGCCTCCTCCCGCTGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAG
  CTGAGCGGAACACCGGCCCGCCGTCGCGGCAGCTGCTTCACCCCTCTCTCTGCAGCCATG
  GGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGC
  GCGGCCTCCGAGCCCTGCCGGGCGGTCTTCAAGGAGGCTGAAGTGACCTTGAAGGCGGAA
  GGCCCCGAACAAGAACCCCGGCCAAGCGCTGGGGAAAGTATTCATGGGCTTGCCTGGGCA
  AAACCCACTTTGTTTACCACTGAAAAGATGAACTCCCTGGGCCGAATGGCAAGCCGTCCC
  AGAAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001793 unedited
  NCATCGTGAGGTACTTGCAGGCCAGAGAGCACTGGGGAGGGTCACAGGTGCCCCCGGATC
  TGTTAGAAAAGCTATGACCGCGGCCGCAATCTAGAGTCGACAAGCTTGATATCGGTACCG
  GGCCCCCCCTCGAAGGATCAGGCCCTTATGGCCGGATCCAGCGCTGGAGAGTTTTTTTTT
  TTTTTTTGGGAAAAGTTTCTTTAATAAAAAAGTTCTAGTACATATACACGATTGTCCTCA
  CCCTTCATCTATAGCAACGCAACAGGGAAAATAAAAAATAAGGGGCAACCTAGGCACACT
  CAGTATAAAAACGCAGAGATCCATCCGAATGGGAGGCATTGGGGTCTGGAAACCAGAAAT
  GCAGGACGGCCAGTGGGCCCAGCAGCTCTGGGCTGCACTTTTGAAGAACTTTCTCTAACG
  TTTTGAAGATAGCATTAAAAAAAAAAATTAAGTTGCACCAGGAGGCCTAAGAAGGTTCCA
  TTCCAGAGAGAAAGTCCACTGTAGGTCAGTCACAGCAGGCCCAGGCCCAGGACACAGGGT
  TGAGCATTTTACGGCAGGTAAGAGGCTTCTGGAAACTTGGCCTCTGAGGCAACCCTGGCC
  CAAGTGGAGAGGTTTTCAGTGCTGAAGTCAAACTGCCCAATTCCTCCATCCTGGAAGGCT
  AAAGAAACAACCACTCTAACGTCAGACTCATAGCCTGTCTCCGCCAAGTTGCTACCGCCA
  CTTCCTGACAAGCTTCGAAGTCCTTAGCTGAAGGGGGAACTGAGACCCCCTTGGAAATGC
  TCTGTGCCCTGACCTTTTGATCCCAACCCCTGGAGGCCGGCCGCCTTAATCCTCT
  
• Restriction Sites: Please inquire
• ACCN: NM_001793
• Insert Size: 3700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: There are 9 nucleotide difference between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substitution of 1 amino acid.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001793.3, NP_001784.2
• RefSeq Size: 3649 bp
• RefSeq ORF: 2490 bp
• Locus ID: 1001
• Cytogenetics: 16q22.1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: 'This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]'
  Transcript Variant: This variant (1) encodes the longest isoform (1).