IHH (NM_002181) Human Untagged Clone

CAT#: SC303139

IHH (untagged)-Human Indian hedgehog (IHH)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IHH
• Synonyms: BDA1; HHG2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002181 edited
  ATGTCTCCCGCCCGGCTCCGGCCCCGACTGCACTTCTGCCTGGTCCTGTTGCTGCTGCTG
  GTGGTGCCGGCGGCATGGGGCTGCGGGCCGGGTCGGGTGGTGGGCAGCCGCCGGCGACCG
  CCACGCAAACTCGTGCCGCTCGCCTACAAGCAGTTCAGCCCCAATGTGCCCGAGAAGACC
  CTGGGCGCCAGCGGACGCTATGAAGGCAAGATCGCTCGCAGCTCCGAGCGCTTCAAGGAG
  CTCACCCCCAATTACAATCCAGACATCATCTTCAAGGACGAGGAGAACACAGGCGCCGAC
  CGCCTCATGACCCAGCGCTGCAAGGACCGCCTGAACTCGCTGGCTATCTCGGTGATGAAC
  CAGTGGCCCGGTGTGAAGCTGCGGGTGACCGAGGGCTGGGACGAGGACGGCCACCACTCA
  GAGGAGTCCCTGCATTATGAGGGCCGCGCGGTGGACATCACCACATCAGACCGCGACCGC
  AATAAGTATGGACTGCTGGCGCGCTTGGCAGTGGAGGCCGGCTTTGACTGGGTGTATTAC
  GAGTCAAAGGCCCACGTGCATTGCTCCGTCAAGTCCGAGCACTCGGCCGCAGCCAAGACA
  GGCGGCTGCTTCCCTGCCGGAGCCCAGGTACGCCTGGAGAGTGGGGCGCGTGTGGCCTTG
  TCAGCCGTGAGGCCGGGAGACCGTGTGCTGGCCATGGGGGAGGATGGGAGCCCCACCTTC
  AGCGATGTGCTCATTTTCCTGGACCGCGAGCCTCACAGGCTGAGAGCCTTCCAGGTCATC
  GAGACTCAGGACCCCCCACGCCGCCTGGCACTCACACCCGCTCACCTGCTCTTTACGGCT
  GACAATCACACGGAGCCGGCAGCCCGCTTCCGGGCCACATTTGCCAGCCACGTGCAGCCT
  GGCCAGTACGTGCTGGTGGCTGGGGTGCCAGGCCTGCAGCCTGCCCGCGTGGCAGCTGTC
  TCTACACACGTGGCCCTCGGGGCCTACGCCCCGCTCACAAAGCATGGGACACTGGTGGTG
  GAGGATGTGGTGGCATCCTGCTTCGCGGCCGTGGCTGACCACCACCTGGCTCAGTTGGCC
  TTCTGGCCCCTGAGACTCTTTCACAGCTTGGCATGGGGCAGCTGGACCCCGGGGGAGGGT
  GTGCATTGGTACCCCCAGCTGCTCTACCGCCTGGGGCGTCTCCTGCTAGAAGAGGGCAGC
  TTCCACCCACTGGGCATGTCCGGGGCAGGGAGCTGAAAGGACTCCACCGCTGCCCTCCTG
  GAACTGCTGTACTGGGTCCAGAAGCCTCTCAGCCAGGAGGGAGCTGGCCCTGGAAGGGAC
  CTGAGCTGGGGGACACTGGCTCCTGCCATCTCCTCTGCCATGAAGATACACCATTGAGAC
  TTGACTGGGCAACACCAGCGTCCCCCACCCCCGTCGTGGTGTAGTCATAGAGCTGCAAGC
  TGAGCTGGCGAGGGGATGGTTGTTGACCCCTCTCTCCTAGAGACCTTGAGGCTGGCACGG
  CGACTCCCAACTCAGCCTGCTCTCACTACGAGTTTTCATACTCTGCCTCCCCCATTGGGG
  AGGGCCCATTCCATCCATCTTAGGCCCCTTTGGGTGGGCTTGCGCCTCAGTTGATGCTGC
  TAAATTCCCTGGGAGCCAGCATGGATCTGGCTGGACCCGATGCTGTCCAGAACTGGGAAG
  GCCACAGGGGTGGGGCAGCCATCCCGGCCATTCTGAGGTATGACATTCCTCCCCGGCCAC
  ACTCCTCAAGACACATCCAGAGACTGTTGCTGTCTGTGGGCAGAGTTCTGTGTTCTGGCC
  AATGTGACCGTAGTGCCGGGGACTGGGGGAGGTGGGTTGGATGTGCTTGCCACCCCCCCG
  GCTAAGCTCCCCCTTCTGCTGAACCATGATCCCCACCCCCTCCGCCGGTCAGTCTCCCAT
  ACCTTATTTATTGGAGTGGAGGGGGAAGCCCATGGGAGAATTTTGGGGATGTTTTGGTCT
  TTTCTTCCTTTTGTAATAAAAATTATTTAAGTTGTTAGAAAAAAAAAAAAAAAAAAAAAA
  A
  
• Restriction Sites: Please inquire
• ACCN: NM_002181
• Insert Size: 2100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_002181.1.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002181.1, NP_002172.1
• RefSeq Size: 1236 bp
• RefSeq ORF: 1236 bp
• Locus ID: 3549
• Cytogenetics: 2q35
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease, Transmembrane
• Protein Pathways: Hedgehog signaling pathway
• Gene Summary: 'This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015]'