ITPR3 (NM_002224) Human Untagged Clone

CAT#: SC303153

ITPR3 (untagged)-Human inositol 1,4,5-trisphosphate receptor, type 3 (ITPR3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ITPR3
• Synonyms: IP3R; IP3R3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002224, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGTGAAATGTCCAGCTTTCTTCACATCGGGGACATCGTCTCCCTGTACGCCGAGGGCTCCGTCAATG
  GCTTCATCAGCACTTTGGGGCTGGTGGATGACCGCTGTGTGGTGGAGCCCGCGGCCGGGGACCTGGACAA
  CCCCCCTAAGAAGTTCCGTGACTGCCTCTTCAAGGTGTGCCCCATGAACCGCTACTCGGCCCAGAAGCAG
  TACTGGAAGGCCAAGCAGACTAAGCAGGACAAGGAGAAGATCGCTGATGTGGTGTTGCTGCAGAAGCTGC
  AGCATGCGGCGCAGATGGAGCAGAAGCAAAATGACACGGAGAACAAGAAGGTGCATGGGGATGTCGTGAA
  GTATGGCAGTGTGATCCAGCTCCTGCACATGAAGAGCAACAAGTACCTGACAGTGAACAAGCGGCTTCCG
  GCCTTGCTGGAGAAGAACGCCATGCGGGTGACTCTGGATGCCACAGGCAACGAGGGTTCCTGGCTCTTCA
  TCCAGCCCTTCTGGAAGCTGCGGAGCAACGGGGACAACGTGGTCGTGGGGGACAAGGTGATCCTGAATCC
  TGTCAATGCCGGGCAGCCTCTGCATGCCAGCAATTACGAGCTCAGCGACAACGCCGGCTGCAAGGAGGTC
  AATTCTGTGAACTGCAACACCAGCTGGAAGATCAACCTGTTTATGCAGTTTCGGGACCACCTGGAGGAGG
  TGTTGAAAGGGGGAGACGTGGTGCGGCTGTTCCATGCGGAGCAGGAGAAGTTCCTGACGTGTGACGAGTA
  CAAGGGCAAGCTGCAGGTGTTCCTGCGAACTACACTGCGCCAGTCTGCCACCTCGGCCACCAGCTCCAAT
  GCTCTCTGGGAGGTGGAGGTGGTCCACCACGACCCCTGCCGTGGAGGAGCTGGGCACTGGAATGGCTTGT
  ACCGCTTCAAGCACCTGGCTACAGGCAACTACCTGGCTGCTGAGGAGAACCCCAGTTACAAAGGTGATGC
  CTCAGATCCCAAGGCAGCAGGAATGGGGGCACAGGGCCGCACAGGCCGCAGGAATGCTGGGGAGAAGATC
  AAGTACTGCCTGGTGGCTGTGCCTCATGGCAATGACATCGCCTCTCTCTTTGAGCTGGACCCCACCACCT
  TGCAGAAAACCGACTCTTTCGTGCCCCGGAACTCGTACGTCCGGCTGCGGCACCTCTGCACCAACACGTG
  GATTCAGAGCACCAATGTGCCCATTGACATCGAGGAGGAGCGGCCCATCCGGCTCATGCTGGGCACCTGC
  CCCACCAAGGAGGACAAGGAGGCCTTTGCCATCGTGTCAGTGCCCGTGTCTGAGATCCGAGACCTGGACT
  TTGCCAATGACGCCAGCTCCATGCTGGCCAGTGCCGTGGAGAAACTCAACGAGGGCTTCATCAGCCAGAA
  TGACCGCAGGTTTGTCATCCAGCTGCTGGAAGACCTGGTGTTCTTTGTCAGCGATGTCCCCAACAATGGG
  CAGAATGTCCTGGACATCATGGTCACTAAGCCCAACCGGGAACGGCAGAAGCTGATGAGGGAGCAGAACA
  TCCTCAAACAGGTCTTTGGCATTCTGAAGGCCCCGTTCCGTGAGAAGGGGGGTGAAGGTCCCCTGGTGCG
  GCTGGAGGAGCTGTCAGACCAGAAGAACGCCCCCTACCAGCACATGTTCCGCCTGTGCTACCGCGTGTTG
  CGGCATTCCCAGGAGGACTACCGCAAGAACCAGGAGCACATTGCCAAGCAGTTTGGGATGATGCAGTCCC
  AGATTGGCTACGACATCCTGGCCGAGGACACCATCACTGCCCTGCTGCACAACAACCGCAAGCTCCTGGA
  AAAGCACATCACCAAGACCGAGGTGGAGACCTTCGTCAGCCTTGTGCGCAAGAACCGGGAGCCCAGGTTC
  CTGGACTACCTCTCTGACCTGTGTGTGTCCAACCACATCGCCATCCCCGTCACCCAAGAGCTCATCTGCA
  AGTGTGTGCTGGACCCCAAGAACAGTGACATTCTCATCCGGACCGAGCTTCGGCCCGTGAAGGAGATGGC
  CCAATCCCACGAGTACCTGAGCATCGAGTACTCAGAAGAGGAAGTGTGGCTCACGTGGACTGACAAGAAT
  AACGAGCATCATGAGAAGAGTGTGAGGCAGCTGGCCCAGGAGGCGCGGGCCGGCAACGCCCACGACGAGA
  ATGTGCTCAGCTACTACAGGTACCAGCTGAAGCTCTTTGCCCGCATGTGCTTGGACCGCCAGTACTTGGC
  CATCGACGAGATCTCCCAGCAGCTGGGCGTGGACCTGATTTTCCTGTGCATGGCAGACGAGATGCTGCCC
  TTTGACCTGCGCGCCTCCTTCTGCCACCTGATGCTGCACGTGCACGTGGACCGTGACCCCCAGGAGCTGG
  TCACGCCGGTCAAGTTTGCCCGTCTCTGGACTGAGATCCCCACAGCCATCACCATCAAGGACTATGATTC
  CAACCTCAACGCGTCCCGAGATGACAAGAAGAACAAGTTTGCCAACACCATGGAGTTCGTGGAGGACTAC
  CTCAACAATGTAGTCAGCGAGGCCGTGCCCTTTGCCAACGAGGAGAAGAACAAGCTCACTTTTGAGGTGG
  TCAGCCTGGCGCACAATCTCATCTACTTCGGCTTCTACAGCTTCAGCGAGCTGCTGCGGCTCACTCGCAC
  ACTGCTGGGCATCATCGACTGTGTGCAGGGGCCCCCGGCCATGCTGCAGGCCTATGAGGACCCCGGTGGC
  AAGAATGTGCGGCGGTCCATCCAGGGCGTGGGGCACATGATGTCCACCATGGTGCTGAGCCGCAAGCAGT
  CCGTCTTCAGTGCCCCCAGCCTGTCTGCTGGGGCCAGTGCTGCTGAGCCGCTGGACAGAAGCAAGTTTGA
  GGAGAATGAGGACATTGTGGTGATGGAGACCAAGCTGAAGATCCTGGAAATCCTTCAGTTCATCCTCAAT
  GTCCGCCTGGATTACCGCATATCCTACCTGCTGTCTGTCTTCAAGAAGGAGTTTGTGGAGGTGTTTCCCA
  TGCAGGACAGTGGGGCTGATGGCACAGCCCCTGCCTTCGACTCTACCACTGCCAACATGAACCTGGATCG
  CATCGGGGAGCAGGCGGAGGCCATGTTTGGAGTGGGGAAGACAAGCAGCATGCTGGAGGTGGATGACGAG
  GGCGGCCGCATGTTCCTGCGCGTGCTCATCCACCTCACCATGCACGACTATGCGCCGCTGGTCTCGGGTG
  CCCTGCAGCTGCTCTTCAAGCACTTCAGCCAGCGCCAGGAGGCCATGCACACCTTCAAGCAGGTTCAGCT
  GCTGATCTCAGCGCAGGACGTGGAGAACTACAAGGTGATCAAGTCGGAGCTGGACCGGCTGCGGACCATG
  GTGGAGAAGTCAGAGCTGTGGGTGGACAAGAAGGGCAGTGGCAAGGGTGAGGAGGTGGAGGCAGGCGCCG
  CCAAGGACAAGAAAGAGCGTCCCACGGACGAGGAGGGCTTTCTGCACCCACCAGGGGAGAAAAGCAGTGA
  GAACTACCAGATCGTCAAGGGCATCCTGGAAAGGCTGAACAAGATGTGCGGGGTTGGGGAGCAAATGAGG
  AAGAAGCAGCAACGGCTGCTGAAGAACATGGATGCCCACAAGGTCATGCTGGACCTGCTGCAGATCCCCT
  ATGACAAGGGTGATGCCAAGATGATGGAGATCCTGCGCTACACGCACCAGTTCCTGCAGAAGTTCTGTGC
  AGGGAACCCCGGCAACCAGGCCCTGCTGCACAAACACCTGCACCTCTTCCTCACGCCAGGGCTCCTGGAG
  GCAGAGACCATGCAGCACATCTTCCTGAACAACTATCAGCTCTGCTCCGAGATCAGCGAGCCTGTGTTGC
  AGCACTTCGTGCACCTGCTGGCCACGCACGGGCGCCATGTGCAGTACCTGGACTTCCTGCACACCGTCAT
  TAAGGCCGAGGGCAAGTACGTCAAGAAGTGCCAGGACATGATCATGACTGAGCTGACCAATGCAGGTGAC
  GATGTGGTCGTGTTCTACAATGATAAGGCATCGCTGGCCCACCTGCTGGACATGATGAAGGCCGCCCGCG
  ACGGCGTGGAGGACCACAGCCCCCTCATGTACCACATTTCCCTGGTGGACCTGCTGGCCGCCTGTGCCGA
  GGGCAAAAACGTCTACACTGAGATCAAGTGCACCTCCCTGCTGCCGCTGGAGGACGTGGTGTCTGTGGTG
  ACGCATGAGGACTGCATCACTGAGGTGAAAATGGCCTATGTGAACTTCGTGAACCACTGCTACGTGGACA
  CGGAGGTGGAGATGAAGGAGATCTACACCAGCAACCACATCTGGACGCTCTTTGAGAACTTCACCCTGGA
  CATGGCTCGGGTCTGCAGCAAGCGTGAGAAGCGCGTGGCTGACCCCACCTTGGAGAAGTACGTGCTGAGC
  GTTGTGCTGGACACCATCAACGCCTTCTTCAGCTCCCCATTCTCTGAGAACAGCACTTCCCTGCAGACAC
  ACCAGACGATTGTGGTGCAGCTGCTGCAGTCTACCACACGCCTCCTCGAGTGTCCGTGGCTACAGCAGCA
  GCACAAGGGCTCCGTGGAGGCCTGCATCCGGACCCTCGCCATGGTGGCCAAGGGCCGGGCCATCTTGCTG
  CCCATGGACCTGGATGCCCACATCAGCTCGATGCTCAGCAGTGGAGCCAGCTGTGCAGCTGCCGCCCAGC
  GGAACGCCTCCAGCTACAAGGCAACCACGCGGGCCTTCCCCCGCGTCACCCCCACCGCCAACCAGTGGGA
  CTACAAGAACATCATTGAGAAGCTGCAGGACATCATCACAGCCCTGGAGGAGCGGCTGAAGCCCCTGGTA
  CAGGCTGAGCTGTCCGTGCTGGTGGATGTCCTGCACTGGCCTGAGCTGCTCTTCCTGGAGGGCAGTGAGG
  CCTACCAGCGCTGCGAGAGTGGGGGCTTCCTGTCCAAGCTGATCCAGCACACCAAGGACCTCATGGAGTC
  GGAGGAGAAGCTGTGCATCAAGGTGCTGCGGACCCTGCAGCAGATGCTGCTCAAGAAGACCAAGTACGGG
  GACCGGGGCAACCAGCTGCGCAAGATGCTGCTGCAAAACTACCTCCAGAACCGGAAGTCCACCTCGCGGG
  GGGACCTTCCCGACCCCATAGGCACTGGCCTGGACCCAGACTGGTCGGCAATCGCAGCCACCCAGTGCCG
  GCTGGACAAGGAGGGGGCCACCAAGTTGGTATGCGACCTCATCACCAGCACCAAGAACGAGAAGATCTTC
  CAGGAGAGCATCGGCCTGGCCATCCACCTGCTGGATGGTGGCAACACAGAGATCCAGAAATCCTTCCACA
  ACCTGATGATGAGTGACAAGAAGTCAGAGCGCTTCTTCAAGGTGCTGCACGACCGCATGAAGCGGGCCCA
  GCAGGAGACCAAGTCCACGGTGGCAGTCAACATGAATGACCTGGGCAGCCAGCCACATGAGGACCGCGAG
  CCAGTCGACCCCACCACCAAAGGCCGCGTGGCCTCCTTCTCGATACCTGGCTCCTCATCCCGCTACTCGC
  TGGGCCCCAGCCTGCGCCGGGGGCACGAGGTGAGCGAACGTGTGCAGAGCAGTGAGATGGGCACATCCGT
  GCTCATCATGCAGCCCATCCTGCGCTTTCTGCAGCTGCTGTGTGAGAACCACAACCGGGACCTGCAGAAC
  TTCCTGCGCTGTCAGAACAACAAAACCAACTACAACTTGGTATGCGAGACGCTGCAGTTCCTGGACATCA
  TGTGCGGCAGCACCACGGGCGGCCTGGGGCTGCTGGGGCTCTACATCAATGAGGACAACGTGGGCCTCGT
  CATCCAGACCTTGGAGACCCTCACTGAGTACTGCCAGGGCCCCTGCCATGAGAACCAGACTTGCATTGTG
  ACTCACGAGTCCAATGGCATAGACATCATCACCGCACTGATCCTCAATGACATCAGCCCCCTGTGCAAGT
  ACCGCATGGATCTGGTGCTGCAGCTCAAGGACAATGCCTCCAAGCTGCTCCTGGCTCTGATGGAGAGCCG
  GCATGACAGTGAAAATGCTGAGCGAATCCTCATCAGCCTGCGGCCCCAGGAGCTGGTGGACGTCATCAAG
  AAGGCCTACCTGCAGGAGGAAGAGCGTGAGAACTCGGAGGTGAGCCCACGTGAAGTGGGCCATAACATCT
  ATATCCTGGCGCTGCAGCTCTCCAGGCACAATAAACAGCTGCAGCACCTGCTGAAGCCGGTGAAGCGCAT
  TCAAGAGGAGGAGGCCGAGGGTATCTCTTCCATGCTCAGCCTCAACAACAAGCAGCTGTCACAGATGCTC
  AAGTCCTCAGCGCCAGCACAGGAGGAGGAGGAAGACCCCCTGGCCTACTATGAGAACCACACGTCCCAGA
  TCGAGATTGTGCGGCAGGACCGCAGCATGGAGCAGATCGTGTTCCCAGTGCCCGGCATCTGCCAGTTCCT
  GACGGAGGAAACCAAGCACCGGCTCTTCACCACTACTGAGCAGGACGAGCAGGGCAGCAAAGTGAGCGAC
  TTCTTCGACCAGTCCTCCTTCCTGCACAACGAGATGGAGTGGCAGCGCAAGCTCCGCAGCATGCCGCTGA
  TCTACTGGTTCTCCCGCCGCATGACCCTGTGGGGCAGCATCTCCTTCAACCTGGCCGTGTTTATCAACAT
  CATCATTGCCTTCTTCTACCCTTACATGGAGGGCGCGTCCACAGGCGTGCTGGACTCCCCTCTCATCTCA
  TTGCTCTTCTGGATCCTCATCTGCTTCTCCATCGCGGCCCTGTTCACCAAGCGCTACAGCATCCGCCCCC
  TCATCGTGGCGCTCATCCTGCGCTCCATCTACTATCTGGGCATCGGGCCCACACTCAACATCCTGGGTGC
  CCTCAATCTGACCAACAAGATCGTGTTTGTGGTGAGCTTCGTGGGCAACCGTGGCACCTTCATCCGGGGC
  TATAAGGCCATGGTCATGGACATGGAATTCCTCTACCACGTGGGCTACATCCTGACCAGTGTCCTGGGCC
  TCTTTGCTCATGAGCTGTTCTACAGCATCCTGCTCTTTGACCTCATCTACCGCGAGGAGACGCTGTTCAA
  CGTCATCAAGAGTGTGACCCGCAATGGCCGCTCCATCCTGCTGACAGCCCTGCTGGCCCTCATCCTGGTC
  TACCTCTTCTCCATCGTCGGCTTCCTCTTCCTCAAGGATGACTTCATTCTCGAGGTCGACCGGCTGCCCA
  ACAACCACTCCACAGCCAGCCCCCTGGGGATGCCACATGGAGCTGCTGCATTTGTGGACACCTGCAGTGG
  GGACAAGATGGACTGTGTCTCAGGGCTCTCGGTGCCTGAGGTCCTGGAAGAGGACAGGGAGCTGGACAGC
  ACAGAGCGGGCCTGTGACACTCTGTTGATGTGCATCGTCACTGTCATGAACCATGGGCTACGCAACGGTG
  GTGGCGTGGGCGACATTCTCCGCAAGCCCTCCAAAGATGAGTCTCTCTTCCCAGCCCGAGTGGTCTATGA
  CCTCCTGTTCTTCTTCATCGTCATCATCATTGTGCTGAACCTCATCTTTGGGGTAATCATCGACACCTTC
  GCTGACCTGCGTAGTGAGAAGCAGAAGAAGGAGGAGATTCTTAAGACGACATGCTTCATCTGTGGTCTGG
  AGAGGGACAAGTTTGATAACAAGACAGTGTCATTTGAGGAACACATCAAGCTGGAGCACAACATGTGGAA
  CTACTTGTACTTCATTGTGCTGGTCCGCGTGAAGAACAAGACCGACTACACGGGCCCTGAGAGCTACGTG
  GCCCAGATGATCAAGAACAAGAACCTGGACTGGTTCCCCCGGATGCGGGCCATGTCCCTTGTCAGCAATG
  AGGGCGAGGGGGAGCAGAATGAGATTCGGATTCTCCAGGACAAGCTCAACTCCACCATGAAGCTGGTGTC
  CCACCTCACTGCCCAGCTCAACGAGCTCAAGGAGCAGATGACGGAGCAGCGGAAACGCAGGCAACGCCTA
  GGCTTTGTGGATGTCCAGAACTGCATTAGCCGCTGA
  
  
• Restriction Sites: SgfI-HindIII
• ACCN: NM_002224
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002224.3, NP_002215.2
• RefSeq Size: 9047 bp
• RefSeq ORF: 8016 bp
• Locus ID: 3710
• Cytogenetics: 6p21.31
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway, Gap junction, GnRH signaling pathway, Long-term depression, Long-term potentiation, Oocyte meiosis, Phosphatidylinositol signaling system, Taste transduction, Vascular smooth muscle contraction
• Gene Summary: 'This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010]'