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ITPR3 (NM_002224) Human Tagged ORF Clone
CAT#: RG222737
- TrueORF®
ITPR3 (GFP-tagged) - Human inositol 1,4,5-trisphosphate receptor, type 3 (ITPR3)
"NM_002224" in other vectors (2)
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Symbol | ITPR3 |
| Synonyms | IP3R; IP3R3 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG222737 representing NM_002224
Red=Cloning site Blue=ORF Green=Tags(s) CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAGTGAAATGTCCAGCTTTCTTCACATCGGGGACATCGTCTCCCTGTACGCCGAGGGCTCCGTCAATG GCTTCATCAGCACTTTGGGGCTGGTGGATGACCGCTGTGTGGTGGAGCCCGCGGCCGGGGACCTGGACAA CCCCCCTAAGAAGTTCCGTGACTGCCTCTTCAAGGTGTGCCCCATGAACCGCTACTCGGCCCAGAAGCAG TACTGGAAGGCCAAGCAGACTAAGCAGGACAAGGAGAAGATCGCTGATGTGGTGTTGCTGCAGAAGCTGC AGCATGCGGCGCAGATGGAGCAGAAGCAAAATGACACGGAGAACAAGAAGGTGCATGGGGATGTCGTGAA GTATGGCAGTGTGATCCAGCTCCTGCACATGAAGAGCAACAAGTACCTGACAGTGAACAAGCGGCTTCCG GCCTTGCTGGAGAAGAACGCCATGCGGGTGACTCTGGATGCCACAGGCAACGAGGGTTCCTGGCTCTTCA TCCAGCCCTTCTGGAAGCTGCGGAGCAACGGGGACAACGTGGTCGTGGGGGACAAGGTGATCCTGAATCC TGTCAATGCCGGGCAGCCTCTGCATGCCAGCAATTACGAGCTCAGCGACAACGCCGGCTGCAAGGAGGTC AATTCTGTGAACTGCAACACCAGCTGGAAGATCAACCTGTTTATGCAGTTTCGGGACCACCTGGAGGAGG TGTTGAAAGGGGGAGACGTGGTGCGGCTGTTCCATGCGGAGCAGGAGAAGTTCCTGACGTGTGACGAGTA CAAGGGCAAGCTGCAGGTGTTCCTGCGAACTACACTGCGCCAGTCTGCCACCTCGGCCACCAGCTCCAAT GCTCTCTGGGAGGTGGAGGTGGTCCACCACGACCCCTGCCGTGGAGGAGCTGGGCACTGGAATGGCTTGT ACCGCTTCAAGCACCTGGCTACAGGCAACTACCTGGCTGCTGAGGAGAACCCCAGTTACAAAGGTGATGC CTCAGATCCCAAGGCAGCAGGAATGGGGGCACAGGGCCGCACAGGCCGCAGGAATGCTGGGGAGAAGATC AAGTACTGCCTGGTGGCTGTGCCTCATGGCAATGACATCGCCTCTCTCTTTGAGCTGGACCCCACCACCT TGCAGAAAACCGACTCTTTCGTGCCCCGGAACTCGTACGTCCGGCTGCGGCACCTCTGCACCAACACGTG GATTCAGAGCACCAATGTGCCCATTGACATCGAGGAGGAGCGGCCCATCCGGCTCATGCTGGGCACCTGC CCCACCAAGGAGGACAAGGAGGCCTTTGCCATCGTGTCAGTGCCCGTGTCTGAGATCCGAGACCTGGACT TTGCCAATGACGCCAGCTCCATGCTGGCCAGTGCCGTGGAGAAACTCAACGAGGGCTTCATCAGCCAGAA TGACCGCAGGTTTGTCATCCAGCTGCTGGAAGACCTGGTGTTCTTTGTCAGCGATGTCCCCAACAATGGG CAGAATGTCCTGGACATCATGGTCACTAAGCCCAACCGGGAACGGCAGAAGCTGATGAGGGAGCAGAACA TCCTCAAACAGGTCTTTGGCATTCTGAAGGCCCCGTTCCGTGAGAAGGGGGGTGAAGGTCCCCTGGTGCG GCTGGAGGAGCTGTCAGACCAGAAGAACGCCCCCTACCAGCACATGTTCCGCCTGTGCTACCGCGTGTTG CGGCATTCCCAGGAGGACTACCGCAAGAACCAGGAGCACATTGCCAAGCAGTTTGGGATGATGCAGTCCC AGATTGGCTACGACATCCTGGCCGAGGACACCATCACTGCCCTGCTGCACAACAACCGCAAGCTCCTGGA AAAGCACATCACCAAGACCGAGGTGGAGACCTTCGTCAGCCTTGTGCGCAAGAACCGGGAGCCCAGGTTC CTGGACTACCTCTCTGACCTGTGTGTGTCCAACCACATCGCCATCCCCGTCACCCAAGAGCTCATCTGCA AGTGTGTGCTGGACCCCAAGAACAGTGACATTCTCATCCGGACCGAGCTTCGGCCCGTGAAGGAGATGGC CCAATCCCACGAGTACCTGAGCATCGAGTACTCAGAAGAGGAAGTGTGGCTCACGTGGACTGACAAGAAT AACGAGCATCATGAGAAGAGTGTGAGGCAGCTGGCCCAGGAGGCGCGGGCCGGCAACGCCCACGACGAGA ATGTGCTCAGCTACTACAGGTACCAGCTGAAGCTCTTTGCCCGCATGTGCTTGGACCGCCAGTACTTGGC CATCGACGAGATCTCCCAGCAGCTGGGCGTGGACCTGATTTTCCTGTGCATGGCAGACGAGATGCTGCCC TTTGACCTGCGCGCCTCCTTCTGCCACCTGATGCTGCACGTGCACGTGGACCGTGACCCCCAGGAGCTGG TCACGCCGGTCAAGTTTGCCCGTCTCTGGACTGAGATCCCCACAGCCATCACCATCAAGGACTATGATTC CAACCTCAACGCGTCCCGAGATGACAAGAAGAACAAGTTTGCCAACACCATGGAGTTCGTGGAGGACTAC CTCAACAATGTAGTCAGCGAGGCCGTGCCCTTTGCCAACGAGGAGAAGAACAAGCTCACTTTTGAGGTGG TCAGCCTGGCGCACAATCTCATCTACTTCGGCTTCTACAGCTTCAGCGAGCTGCTGCGGCTCACTCGCAC ACTGCTGGGCATCATCGACTGTGTGCAGGGGCCCCCGGCCATGCTGCAGGCCTATGAGGACCCCGGTGGC AAGAATGTGCGGCGGTCCATCCAGGGCGTGGGGCACATGATGTCCACCATGGTGCTGAGCCGCAAGCAGT CCGTCTTCAGTGCCCCCAGCCTGTCTGCTGGGGCCAGTGCTGCTGAGCCGCTGGACAGAAGCAAGTTTGA GGAGAATGAGGACATTGTGGTGATGGAGACCAAGCTGAAGATCCTGGAAATCCTTCAGTTCATCCTCAAT GTCCGCCTGGATTACCGCATATCCTACCTGCTGTCTGTCTTCAAGAAGGAGTTTGTGGAGGTGTTTCCCA TGCAGGACAGTGGGGCTGATGGCACAGCCCCTGCCTTCGACTCTACCACTGCCAACATGAACCTGGATCG CATCGGGGAGCAGGCGGAGGCCATGTTTGGAGTGGGGAAGACAAGCAGCATGCTGGAGGTGGATGACGAG GGCGGCCGCATGTTCCTGCGCGTGCTCATCCACCTCACCATGCACGACTATGCGCCGCTGGTCTCGGGTG CCCTGCAGCTGCTCTTCAAGCACTTCAGCCAGCGCCAGGAGGCCATGCACACCTTCAAGCAGGTTCAGCT GCTGATCTCAGCGCAGGACGTGGAGAACTACAAGGTGATCAAGTCGGAGCTGGACCGGCTGCGGACCATG GTGGAGAAGTCAGAGCTGTGGGTGGACAAGAAGGGCAGTGGCAAGGGTGAGGAGGTGGAGGCAGGCGCCG CCAAGGACAAGAAAGAGCGTCCCACGGACGAGGAGGGCTTTCTGCACCCACCAGGGGAGAAAAGCAGTGA GAACTACCAGATCGTCAAGGGCATCCTGGAAAGGCTGAACAAGATGTGCGGGGTTGGGGAGCAAATGAGG AAGAAGCAGCAACGGCTGCTGAAGAACATGGATGCCCACAAGGTCATGCTGGACCTGCTGCAGATCCCCT ATGACAAGGGTGATGCCAAGATGATGGAGATCCTGCGCTACACGCACCAGTTCCTGCAGAAGTTCTGTGC AGGGAACCCCGGCAACCAGGCCCTGCTGCACAAACACCTGCACCTCTTCCTCACGCCAGGGCTCCTGGAG GCAGAGACCATGCAGCACATCTTCCTGAACAACTATCAGCTCTGCTCCGAGATCAGCGAGCCTGTGTTGC AGCACTTCGTGCACCTGCTGGCCACGCACGGGCGCCATGTGCAGTACCTGGACTTCCTGCACACCGTCAT TAAGGCCGAGGGCAAGTACGTCAAGAAGTGCCAGGACATGATCATGACTGAGCTGACCAATGCAGGTGAC GATGTGGTCGTGTTCTACAATGATAAGGCATCGCTGGCCCACCTGCTGGACATGATGAAGGCCGCCCGCG ACGGCGTGGAGGACCACAGCCCCCTCATGTACCACATTTCCCTGGTGGACCTGCTGGCCGCCTGTGCCGA GGGCAAAAACGTCTACACTGAGATCAAGTGCACCTCCCTGCTGCCGCTGGAGGACGTGGTGTCTGTGGTG ACGCATGAGGACTGCATCACTGAGGTGAAAATGGCCTATGTGAACTTCGTGAACCACTGCTACGTGGACA CGGAGGTGGAGATGAAGGAGATCTACACCAGCAACCACATCTGGACGCTCTTTGAGAACTTCACCCTGGA CATGGCTCGGGTCTGCAGCAAGCGTGAGAAGCGCGTGGCTGACCCCACCTTGGAGAAGTACGTGCTGAGC GTTGTGCTGGACACCATCAACGCCTTCTTCAGCTCCCCATTCTCTGAGAACAGCACTTCCCTGCAGACAC ACCAGACGATTGTGGTGCAGCTGCTGCAGTCTACCACACGCCTCCTCGAGTGTCCGTGGCTACAGCAGCA GCACAAGGGCTCCGTGGAGGCCTGCATCCGGACCCTCGCCATGGTGGCCAAGGGCCGGGCCATCTTGCTG CCCATGGACCTGGATGCCCACATCAGCTCGATGCTCAGCAGTGGAGCCAGCTGTGCAGCTGCCGCCCAGC GGAACGCCTCCAGCTACAAGGCAACCACGCGGGCCTTCCCCCGCGTCACCCCCACCGCCAACCAGTGGGA CTACAAGAACATCATTGAGAAGCTGCAGGACATCATCACAGCCCTGGAGGAGCGGCTGAAGCCCCTGGTA CAGGCTGAGCTGTCCGTGCTGGTGGATGTCCTGCACTGGCCTGAGCTGCTCTTCCTGGAGGGCAGTGAGG CCTACCAGCGCTGCGAGAGTGGGGGCTTCCTGTCCAAGCTGATCCAGCACACCAAGGACCTCATGGAGTC GGAGGAGAAGCTGTGCATCAAGGTGCTGCGGACCCTGCAGCAGATGCTGCTCAAGAAGACCAAGTACGGG GACCGGGGCAACCAGCTGCGCAAGATGCTGCTGCAAAACTACCTCCAGAACCGGAAGTCCACCTCGCGGG GGGACCTTCCCGACCCCATAGGCACTGGCCTGGACCCAGACTGGTCGGCAATCGCAGCCACCCAGTGCCG GCTGGACAAGGAGGGGGCCACCAAGTTGGTATGCGACCTCATCACCAGCACCAAGAACGAGAAGATCTTC CAGGAGAGCATCGGCCTGGCCATCCACCTGCTGGATGGTGGCAACACAGAGATCCAGAAATCCTTCCACA ACCTGATGATGAGTGACAAGAAGTCAGAGCGCTTCTTCAAGGTGCTGCACGACCGCATGAAGCGGGCCCA GCAGGAGACCAAGTCCACGGTGGCAGTCAACATGAATGACCTGGGCAGCCAGCCACATGAGGACCGCGAG CCAGTCGACCCCACCACCAAAGGCCGCGTGGCCTCCTTCTCGATACCTGGCTCCTCATCCCGCTACTCGC TGGGCCCCAGCCTGCGCCGGGGGCACGAGGTGAGCGAACGTGTGCAGAGCAGTGAGATGGGCACATCCGT GCTCATCATGCAGCCCATCCTGCGCTTTCTGCAGCTGCTGTGTGAGAACCACAACCGGGACCTGCAGAAC TTCCTGCGCTGTCAGAACAACAAAACCAACTACAACTTGGTATGCGAGACGCTGCAGTTCCTGGACATCA TGTGCGGCAGCACCACGGGCGGCCTGGGGCTGCTGGGGCTCTACATCAATGAGGACAACGTGGGCCTCGT CATCCAGACCTTGGAGACCCTCACTGAGTACTGCCAGGGCCCCTGCCATGAGAACCAGACTTGCATTGTG ACTCACGAGTCCAATGGCATAGACATCATCACCGCACTGATCCTCAATGACATCAGCCCCCTGTGCAAGT ACCGCATGGATCTGGTGCTGCAGCTCAAGGACAATGCCTCCAAGCTGCTCCTGGCTCTGATGGAGAGCCG GCATGACAGTGAAAATGCTGAGCGAATCCTCATCAGCCTGCGGCCCCAGGAGCTGGTGGACGTCATCAAG AAGGCCTACCTGCAGGAGGAAGAGCGTGAGAACTCGGAGGTGAGCCCACGTGAAGTGGGCCATAACATCT ATATCCTGGCGCTGCAGCTCTCCAGGCACAATAAACAGCTGCAGCACCTGCTGAAGCCGGTGAAGCGCAT TCAAGAGGAGGAGGCCGAGGGTATCTCTTCCATGCTCAGCCTCAACAACAAGCAGCTGTCACAGATGCTC AAGTCCTCAGCGCCAGCACAGGAGGAGGAGGAAGACCCCCTGGCCTACTATGAGAACCACACGTCCCAGA TCGAGATTGTGCGGCAGGACCGCAGCATGGAGCAGATCGTGTTCCCAGTGCCCGGCATCTGCCAGTTCCT GACGGAGGAAACCAAGCACCGGCTCTTCACCACTACTGAGCAGGACGAGCAGGGCAGCAAAGTGAGCGAC TTCTTCGACCAGTCCTCCTTCCTGCACAACGAGATGGAGTGGCAGCGCAAGCTCCGCAGCATGCCGCTGA TCTACTGGTTCTCCCGCCGCATGACCCTGTGGGGCAGCATCTCCTTCAACCTGGCCGTGTTTATCAACAT CATCATTGCCTTCTTCTACCCTTACATGGAGGGCGCGTCCACAGGCGTGCTGGACTCCCCTCTCATCTCA TTGCTCTTCTGGATCCTCATCTGCTTCTCCATCGCGGCCCTGTTCACCAAGCGCTACAGCATCCGCCCCC TCATCGTGGCGCTCATCCTGCGCTCCATCTACTATCTGGGCATCGGGCCCACACTCAACATCCTGGGTGC CCTCAATCTGACCAACAAGATCGTGTTTGTGGTGAGCTTCGTGGGCAACCGTGGCACCTTCATCCGGGGC TATAAGGCCATGGTCATGGACATGGAATTCCTCTACCACGTGGGCTACATCCTGACCAGTGTCCTGGGCC TCTTTGCTCATGAGCTGTTCTACAGCATCCTGCTCTTTGACCTCATCTACCGCGAGGAGACGCTGTTCAA CGTCATCAAGAGTGTGACCCGCAATGGCCGCTCCATCCTGCTGACAGCCCTGCTGGCCCTCATCCTGGTC TACCTCTTCTCCATCGTCGGCTTCCTCTTCCTCAAGGATGACTTCATTCTCGAGGTCGACCGGCTGCCCA ACAACCACTCCACAGCCAGCCCCCTGGGGATGCCACATGGAGCTGCTGCATTTGTGGACACCTGCAGTGG GGACAAGATGGACTGTGTCTCAGGGCTCTCGGTGCCTGAGGTCCTGGAAGAGGACAGGGAGCTGGACAGC ACAGAGCGGGCCTGTGACACTCTGTTGATGTGCATCGTCACTGTCATGAACCATGGGCTACGCAACGGTG GTGGCGTGGGCGACATTCTCCGCAAGCCCTCCAAAGATGAGTCTCTCTTCCCAGCCCGAGTGGTCTATGA CCTCCTGTTCTTCTTCATCGTCATCATCATTGTGCTGAACCTCATCTTTGGGGTAATCATCGACACCTTC GCTGACCTGCGTAGTGAGAAGCAGAAGAAGGAGGAGATTCTTAAGACGACATGCTTCATCTGTGGTCTGG AGAGGGACAAGTTTGATAACAAGACAGTGTCATTTGAGGAACACATCAAGCTGGAGCACAACATGTGGAA CTACTTGTACTTCATTGTGCTGGTCCGCGTGAAGAACAAGACCGACTACACGGGCCCTGAGAGCTACGTG GCCCAGATGATCAAGAACAAGAACCTGGACTGGTTCCCCCGGATGCGGGCCATGTCCCTTGTCAGCAATG AGGGCGAGGGGGAGCAGAATGAGATTCGGATTCTCCAGGACAAGCTCAACTCCACCATGAAGCTGGTGTC CCACCTCACTGCCCAGCTCAACGAGCTCAAGGAGCAGATGACGGAGCAGCGGAAACGCAGGCAACGCCTA GGCTTTGTGGATGTCCAGAACTGCATTAGCCGC CAAGCTTAACTAGCTAGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG222737 representing NM_002224
Red=Cloning site Green=Tags(s) MSEMSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQ YWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLP ALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEV NSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYKGKLQVFLRTTLRQSATSATSSN ALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAAGMGAQGRTGRRNAGEKI KYCLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNVPIDIEEERPIRLMLGTC PTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNG QNVLDIMVTKPNRERQKLMREQNILKQVFGILKAPFREKGGEGPLVRLEELSDQKNAPYQHMFRLCYRVL RHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRF LDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDKN NEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISQQLGVDLIFLCMADEMLP FDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDKKNKFANTMEFVEDY LNNVVSEAVPFANEEKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPPAMLQAYEDPGG KNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFEENEDIVVMETKLKILEILQFILN VRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSTTANMNLDRIGEQAEAMFGVGKTSSMLEVDDE GGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTM VEKSELWVDKKGSGKGEEVEAGAAKDKKERPTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGVGEQMR KKQQRLLKNMDAHKVMLDLLQIPYDKGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKHLHLFLTPGLLE AETMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKAEGKYVKKCQDMIMTELTNAGD DVVVFYNDKASLAHLLDMMKAARDGVEDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVV THEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNHIWTLFENFTLDMARVCSKREKRVADPTLEKYVLS VVLDTINAFFSSPFSENSTSLQTHQTIVVQLLQSTTRLLECPWLQQQHKGSVEACIRTLAMVAKGRAILL PMDLDAHISSMLSSGASCAAAAQRNASSYKATTRAFPRVTPTANQWDYKNIIEKLQDIITALEERLKPLV QAELSVLVDVLHWPELLFLEGSEAYQRCESGGFLSKLIQHTKDLMESEEKLCIKVLRTLQQMLLKKTKYG DRGNQLRKMLLQNYLQNRKSTSRGDLPDPIGTGLDPDWSAIAATQCRLDKEGATKLVCDLITSTKNEKIF QESIGLAIHLLDGGNTEIQKSFHNLMMSDKKSERFFKVLHDRMKRAQQETKSTVAVNMNDLGSQPHEDRE PVDPTTKGRVASFSIPGSSSRYSLGPSLRRGHEVSERVQSSEMGTSVLIMQPILRFLQLLCENHNRDLQN FLRCQNNKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCIV THESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVDVIK KAYLQEEERENSEVSPREVGHNIYILALQLSRHNKQLQHLLKPVKRIQEEEAEGISSMLSLNNKQLSQML KSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPGICQFLTEETKHRLFTTTEQDEQGSKVSD FFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFYPYMEGASTGVLDSPLIS LLFWILICFSIAALFTKRYSIRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRG YKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILV YLFSIVGFLFLKDDFILEVDRLPNNHSTASPLGMPHGAAAFVDTCSGDKMDCVSGLSVPEVLEEDRELDS TERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFIVIIIVLNLIFGVIIDTF ADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYV AQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLNSTMKLVSHLTAQLNELKEQMTEQRKRRQRL GFVDVQNCISR NNNN - GFP Tag - V |
| Restriction Sites |
SgfI-HindIII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_002224 |
| ORF Size | 8013 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002224.3, NP_002215.2 |
| RefSeq Size | 9047 bp |
| RefSeq ORF | 8016 bp |
| Locus ID | 3710 |
| Cytogenetics | 6p21.31 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Alzheimer's disease, Calcium signaling pathway, Gap junction, GnRH signaling pathway, Long-term depression, Long-term potentiation, Oocyte meiosis, Phosphatidylinositol signaling system, Taste transduction, Vascular smooth muscle contraction |
| Gene Summary | 'This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010]' |
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