Periplakin (PPL) (NM_002705) Human Untagged Clone

CAT#: SC303237

PPL (untagged)-Human periplakin (PPL)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPL
• Synonyms: KIAA0568; MGC134872
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002705 edited
  GGTGCGCGCCCGGCCCGCCAGCCGCCGCCGCCCGCACCCCGAGCGCCACCATGAACTCGC
  TCTTCAGGAAGAGAAACAAAGGCAAATACAGCCCCACTGTGCAGACCCGGAGCATCTCTA
  ACAAGGAGCTCTCGGAGCTGATCGAGCAGCTGCAGAAGAATGCCGACCAGGTGGAGAAGA
  ACATCGTGGACACAGAGGCCAAGATGCAGAGTGACCTGGCTCGGCTGCAGGAGGGTCGGC
  AGCCTGAGCACCGGGACGTGACCCTGCAGAAGGTGTTGGACTCTGAGAAGCTGCTCTATG
  TGCTAGAGGCGGATGCGGCCATTGCCAAGCACATGAAGCACCCACAGGGGGACATGATCG
  CCGAGGATATCCGCCAGCTGAAGGAGCGTGTGACCAACCTGCGCGGGAAACACAAGCAGA
  TCTACAGGCTGGCGGTGAAGGAAGTGGATCCACAGGTCAACTGGGCGGCACTGGTGGAGG
  AGAAGCTGGACAAGCTGAACAACCAGAGCTTTGGGACTGACCTGCCGCTGGTGGACCACC
  AAGTGGAGGAGCATAACATCTTCCACAATGAGGTCAAGGCCATCGGGCCCCACCTGGCCA
  AGGACGGGGACAAGGAGCAGAACAGCGAACTCCGGGCCAAGTACCAGAAACTGCTGGCAG
  CATCACAGGCCCGGCAGCAGCACCTGAGTTCGCTGCAGGACTACATGCAGCGCTGCACCA
  ATGAGCTGTACTGGCTGGACCAGCAGGCCAAGGGCCGCATGCAGTACGACTGGAGTGACC
  GCAACCTCGACTACCCCAGCCGCCGGCGCCAGTATGAGAATTTCATCAACCGGAACCTGG
  AGGCCAAAGAGGAGAGAATCAACAAACTGCACAGCGAGGGCGACCAGCTGCTGGCGGCCG
  AGCACCCCGGGAGGAACTCCATTGAGGCGCACATGGAGGCTGTGCACGCAGACTGGAAGG
  AGTACCTGAACCTGCTCATCTGCGAGGAGAGCCACCTCAAGTACATGGAGGACTACCACC
  AGTTTCACGAAGACGTGAAGGACGCTCAGGAGCTGCTGCGCAAGGTGGACTCGGACCTGA
  ACCAGAAGTATGGCCCTGACTTCAAGGACCGGTACCAGATTGAGCTGCTGCTGCGGGAGC
  TGGATGACCAGGAGAAGGTGCTGGACAAGTATGAGGACGTGGTGCAGGGGCTGCAGAAGC
  GAGGCCAGCAGGTGGTGCCCCTCAAGTACCGCCGGGAGACTCCGCTCAAGCCCATCCCCG
  TGGAGGCACTCTGTGACTTTGAGGGGGAGCAGGGCCTGATCTCGCGGGGCTACAGCTACA
  CCCTGCAGAAGAACAACGGGGAGAGCTGGGAGCTCATGGACAGCGCTGGGAACAAGCTGA
  TTGCTCCGGCCGTCTGTTTTGTGATCCCCCCCACAGACCCTGAGGCCCTGGCTCTGGCTG
  ACAGCCTGGGCAGCCAGTACCGGAGCGTGCGGCAGAAGGCAGCTGGGAGCAAACGCACGC
  TGCAGCAGCGGTATGAGGTGCTGAAGACCGAGAATCCCGGAGATGCCTCTGACCTACAGG
  GGCGGCAGCTGCTGGCTGGCTTGGACAAGGTGGCCAGCGACCTGGACCGGCAGGAGAAGG
  CCATCACAGGGATCCTGCGGCCACCACTGGAGCAAGGCCGGGCTGTGCAGGACAGTGCCG
  AGCGGGCCAAGGACCTCAAGAACATCACCAACGAGCTACTGCGGATTGAACCTGAGAAGA
  CGCGGAGCACGGCTGAGGGCGAAGCCTTCATCCAGGCCCTCCCAGGCAGTGGCACCACAC
  CCCTGCTGAGGACCCAGGTGGAGGACACCAACCGGAAATACGAGCACCTCCTGCAGCTGC
  TGGACTTGGCCCAGGAGAAGGTTGATGTGGCCAACCGCCTGGAGAAGAGCCTGCAGCAGA
  GCTGGGAGTTGCTGGCCACACACGAGAACCATCTGAATCAGGATGACACAGTGCCTGAGA
  GCAGCCGTGTCCTGGACAGCAAGGGGCAGGAGCTGGCGGCCATGGCCTGTGAGTTACAGG
  CCCAGAAGTCCCTCCTGGGTGAGGTGGAGCAGAACTTGCAGGCGGCCAAGCAGTGCTCGA
  GCACACTGGCCAGCCGCTTCCAGGAGCACTGCCCGGACCTGGAGCGCCAGGAGGCCGAGG
  TGCACAAGCTGGGCCAGCGTTTCAACAACCTGCGCCAGCAGGTGGAACGCAGGGCGCAGA
  GCCTACAGAGCGCCAAGGCAGCCTACGAGCACTTCCACCGCGGCCATGACCACGTGCTGC
  AGTTCCTAGTCAGCATCCCCAGTTACGAGCCCCAGGAGACAGACAGCCTCAGCCAGATGG
  AGACCAAGCTGAAGAACCAGAAGAACCTGCTAGATGAGATAGCAAGTAGGGAGCAGGAAG
  TACAGAAGATCTGTGCCAATTCCCAGCAGTACCAGCAAGCTGTAAAGGACTATGAGTTAG
  AAGCAGAAAAACTAAGGTCTCTTCTCGACTTGGAGAATGGAAGGAGCAGCCACGTGAGCA
  AGAGAGCCAGGCTCCAATCTCCTGCCACCAAAGTGAAGGAAGAGGAAGCAGCACTTGCCG
  CCAAGTTCACTGAAGTTTATGCCATCAACAGACAGAGGCTGCAGAATCTGGAGTTTGCTC
  TGAATCTCCTCAGACAGCAGCCGGAAGTAGAAGTGACCCATGAGACCCTGCAAAGGAATA
  GGCCGGACTCTGGAGTGGAGGAGGCGTGGAAGATCAGGAAGGAACTGGATGAGGAGACTG
  AGCGGAGGCGGCAGCTGGAGAACGAGGTCAAGAGCACCCAGGAAGAAATCTGGACCTTGA
  GGAATCAGGGGCCTCAGGAATCGGTGGTGAGGAAGGAGGTGCTCAAGAAGGTGCCGGATC
  CCGTGCTGGAGGAGAGCTTCCAGCAGCTGCAGCGGACGCTGGCAGAGGAGCAGCACAAGA
  ACCAGCTGCTGCAGGAGGAGCTGGAGGCACTGCAGCTGCAGCTGCGTGCCCTGGAGCAGG
  AGACCAGAGACGGGGGGCAGGAGTACGTGGTCAAGGAGGTCCTGCGCATCGAGCCTGACA
  GGGCCCAGGCGGATGAGGTCTTGCAGCTGCGGGAGGAGCTGGAGGCACTGAGGCGGCAGA
  AGGGCGCCCGGGAGGCAGAGGTGCTCCTCCTGCAGCAGCGTGTGGCCGCCCTGGCTGAAG
  AGAAGAGCCGGGCGCAGGAGAAGGTCACAGAGAAAGAGGTGGTGAAACTGCAGAATGACC
  CCCAGCTGGAGGCAGAGTACCAGCAGCTGCAGGAGGACCACCAGCGCCAGGACCAGCTCA
  GGGAGAAGCAGGAGGAGGAGCTGAGCTTCCTCCAGGACAAGCTCAAGAGGCTAGAGAAGG
  AGCGGGCCATGGCCGAGGGCAAGATCACCGTCAAGGAGGTGCTCAAGGTGGAGAAGGACG
  CGGCCACCGAGAGGGAGGTCAGCGATCTCACCCGCCAATATGAGGACGAGGCTGCCAAGG
  CTCGCGCTAGCCAGAGGGAGAAGACGGAGCTGCTCCGAAAGATATGGGCCTTGGAGGAGG
  AGAACGCCAAAGTGGTGGTGCAGGAGAAGGTGCGGGAGATCGTGCGGCCAGACCCCAAGG
  CGGAAAGTGAAGTGGCGAACCTCCGCCTGGAGCTTGTGGAGCAGGAGCGAAAGTACCGGG
  GTGCCGAGGAGCAGCTCCGGAGCTACCAGAGTGAGCTGGAGGCCCTCAGGAGGCGAGGCC
  CCCAGGTGGAAGTCAAAGAGGTGACTAAGGAAGTCATTAAGTACAAGACTGACCCTGAGA
  TGGAGAAGGAGCTTCAGCGGCTCAGGGAGGAGATCGTGGACAAGACCAGACTGATCGAAA
  GGTGTGATTTAGAGATCTACCAGCTGAAAAAGGAAATCCAGGCCCTGAAAGACACCAAAC
  CCCAGGTCCAGACCAAAGAGGTGGTCCAGGAGATCCTCCAATTCCAAGAAGACCCTCAAA
  CCAAGGAGGAGGTGGCGTCTCTGAGGGCAAAGCTCTCAGAGGAGCAGAAGAAACAAGTGG
  ATCTGGAGAGGGAAAGAGCTTCCCAGGAAGAGCAGATCGCCCGGAAAGAGGAGGAGCTCT
  CGCGGGTGAAGGAAAGGGTGGTGCAGCAGGAGGTGGTCAGGTATGAGGAGGAGCCAGGCC
  TCCGGGCCGAGGCGAGTGCCTTTGCCGAGAGCATCGATGTGGAGCTGCGGCAGATTGACA
  AGCTGCGGGCAGAGCTGCGGCGGCTGCAGCGCCGGCGCACCGAGCTTGAGCGGCAGCTGG
  AGGAGCTAGAGCGCGAGCGGCAGGCCCGCAGGGAGGCCGAGCGCGAGGTACAGCGGTTGC
  AGCAGCGGCTGGCAGCGCTGGAGCAGGAAGAAGCTGAGGCCCGTGAGAAGGTAACCCATA
  CGCAGAAGGTGGTGCTGCAGCAGGACCCGCAGCAGGCGCGAGAGCATGCCCTGCTCCGAC
  TCCAGCTGGAAGAAGAGCAGCACCGGCGGCAGCTCCTGGAGGGGGAGCTCGAGACCCTCC
  GGAGGAAACTGGCTGCACTGGAGAAGGCGGAGGTCAAGGAGAAGGTGGTGCTCTCCGAGA
  GTGTCCAGGTGGAGAAGGGCGACACCGAGCAAGAGATCCAGAGGCTCAAGAGCAGCCTGG
  AGGAGGAGAGCCGCAGCAAGCGCGAGCTGGACGTCGAGGTGAGCCGGCTGGAAGCCAGGC
  TTTCGGAGCTGGAATTCCATAACTCCAAGTCATCCAAGGAACTAGACTTTCTGAGGGAAG
  AGAACCACAAATTACAGCTGGAGAGGGAAAACCTGCAGCTGGAGACCCGAAGGCTCCAAT
  CGGAAATCAACATGGCAGCGACGGAAACACGAGACCTGCGGAACATGACCGTGGCGGACT
  CTGGGACCAACCATGACTCCAGACTGTGGTCCCTGGAGAGGGAACTGGATGACCTCAAGA
  GGCTCTCCAAGGACAAAGACCTCGAGATCGACGAGCTGCAGAAGCGCCTGGGCTCCGTGG
  CCGTCAAGCGGGAGCAGCGGGAGAACCACCTGCGGCGCTCCATCGTAGTCATCCACCCTG
  ACACAGGCCGCGAGCTGTCCCCGGAGGAAGCCCACCGTGCCGGGCTCATTGACTGGAACA
  TGTTCGTGAAACTCAGAAGCCAGGAGTGCGACTGGGAGGAGATCTCAGTGAAGGGTCCCA
  ATGGGGAGTCCTCAGTGATACACGACAGGAAGTCTGGCAAGAAGTTCTCCATCGAAGAGG
  CCCTGCAGAGTGGCAGGCTGACCCCTGCTCAGTATGACCGCTATGTCAACAAGGATATGT
  CCATCCAGGAGCTGGCGGTCTTGGTATCTGGGCAGAAGTAGGCACAGCTCTTGCAACTCT
  TCGTAACGGCAGACGCTGGCCCTCTCCTACGACGCAGTGACCTCCTTGGTGTCGTCCTCT
  CCCTAGCCCTGGTGCAGGCCAAGCATTTTATACAT
  
• Restriction Sites: Please inquire
• ACCN: NM_002705
• Insert Size: 5900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_002705.3.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002705.3, NP_002696.3
• RefSeq Size: 6256 bp
• RefSeq ORF: 5271 bp
• Locus ID: 5493
• Cytogenetics: 16p13.3
• Gene Summary: 'The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq, Jul 2008]'