Eotaxin 2 (CCL24) (NM_002991) Human Untagged Clone

CAT#: SC303260

CCL24 (untagged)-Human chemokine (C-C motif) ligand 24 (CCL24)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCL24
• Synonyms: Ckb-6; MPIF-2; MPIF2; SCYA24
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002991 edited
  ATGGCAGGCCTGATGACCATAGTAACCAGCCTTCTGTTCCTTGGTGTCTGTGCCCACCAC
  ATCATCCCTACGGGCTCTGTGGTCATCCCCTCTCCCTGCTGCATGTTCTTTGTTTCCAAG
  AGAATTCCTGAGAACCGAGTGGTCAGCTACCAGCTGTCCAGCAGGAGCACATGCCTCAAG
  GCAGGAGTGATCTTCACCACCAAGAAGGGCCAGCAGTTCTGTGGCGACCCCAAGCAGGAG
  TGGGTCCAGAGGTACATGAAGAACCTGGACGCCAAGCAGAAGAAGGCTTCCCCTAGGGCC
  AGGGCAGTGGCTGTCAAGGGCCCTGTCCAGAGATATCCTGGCAACCAAACCACCTGCTAA
  GGGCTAGAGCGGCCGC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002991 unedited
  GGTACGTTTGTATACGACTCCTATAGGGCGGCCGCGTAACTTCCTGCAGCCCGGGGGATC
  CGCCCATGGCAGGCCTGATGACCATAGTAACCAGCCTTCTGTTCCTTGGTGTCTGTGCCC
  ACCACATCATCCCTACGGGCTCTGTGGTCATCCCCTCTCCCTGCTGCATGTTCTTTGTTT
  CCAAGAGAATTCCTGAGAACCGAGTGGTCAGCTACCAGCTGTCCAGCAGGAGCACATGCC
  TCAAGGCAGGAGTGATCTTCACCACCAAGAAGGGCCAGCAGTTCTGTGGCGACCCCAAGC
  AGGAGTGGGTCCAGAGGTACATGAAGAACCTGGACGCCAAGCAGAAGAAGGCTTCCCCTA
  GGGCCAGGGCAGTGGCTGTCAAGGGCCCTGTCCAGAGATATCCTGGCAACCAAACCACCT
  GCTAAGGGCTAGAGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCC
  CTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAG
  CCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGACTAGGTGTCCTTCTATAATAT
  TATGGGGTGGAGGGGGGTGGTATGGAGCAAGGGGCAAGTTGGGAAGACAACCTGTAGGGC
  CTGCGGGGTCTATTGGGAACCAAGCTGGAGTGCAGTGGCACAATCTTGGCTCACTGCAAT
  CTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTTGTTGGATTCCAG
  GCATGCATGACCAGGCTCAGCTAATTTTGTTTTTTGGTAGAGACGGGGTTTCACCATATT
  GGTCAGGCTGGTCTCAACTCTAATCTCAGTGATCTACCCACCTGGCCTCCCAATGTGCTG
  GGAGTACAGGAGTGAACAACATGACTTCTTC
  
  3' Read Nucleotide Sequence

  >Forward primer walk for NM_002991 unedited
  CCCGCCCGTTTGAGCAACTGGGCGGTAGGCGCTGTACGGTGGGAGGGTCTATATAAGCAG
  AGCTCGTTTAGTGAACCGTCAGAATCTTGTAATACGACCCACCACAGGGCGGCCGCGAAC
  CCCTGCAGCCCGGGGGACCCGCCCACGGCAGGCCTGATGACCACAGTAACCAGCCCCCCG
  TTCCCCGGTGCCCGTGCCCACCACATCATCCCTACGGGCCCCGTGGTCACCCCCTCTCCC
  TGCTGCATGCTCTTTGTTTCCAAGAGAATCCCTGAGAACCGAGTGGTCAGCCACCAGCCG
  TCCAGCAGGAGCACATGCCTCAAGGCAGGAGTGACCTTCACCACCAAGAAGGGCCAGCAG
  TTCTGTGGCGACCCCAAGCAGGAGTGGGTCCAGAGGTACATGAAGAACCTGGACGCCAAG
  CAGAAGAAGGCTTCCCCTAGGGCCAGGGCAGTGGCTGTCAAGGGCCCTGTCCAGAGATAT
  CCTGGCAACCAAACCACCTGCTAAGGGCTAGAGCGGCCGCGGTCATAGCTGTTTCCTGAA
  CAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTG
  CCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGACT
  AGGTGTCCTTCTATATATTATGGGTGGAGGGGGTGGGTAATGGAGAAAAAGGTTCAAGTT
  GGGAATGACAACATGTACGGCCTGCGATGTCTATTGGGAACCAAAGTAGTAATGCAGTGG
  ATCTACTCGTCGAGTCACTGCAGTCTCCGACTGCTAGGTTCTAGGCGATACTGCTGGCCT
  CAGCCTTCCGACGTTGATTGGAGTCCATGCGTGGCATGACCAGCTATCTAACTCTGATGT
  ACTGCTAAATGCGGGGTTTA
  
• Restriction Sites: Please inquire
• ACCN: NM_002991
• Insert Size: 400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002991.2, NP_002982.2
• RefSeq Size: 360 bp
• RefSeq ORF: 360 bp
• Locus ID: 6369
• Cytogenetics: 7q11.23
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: 'This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. Finally, the protein is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2020]'