Transglutaminase 3 (TGM3) (NM_003245) Human Untagged Clone

CAT#: SC303288

TGM3 (untagged)-Human transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TGM3
• Synonyms: TGE; UHS2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003245 edited
  GAAGAGGCAGAGGAAGGCGAAACATGGCTGCTCTAGGAGTCCAGAGTATCAACTGGCAGA
  CGGCCTTCAACCGACAAGCGCATCACACAGACAAGTTCTCCAGCCAGGAGCTCATCTTGC
  GGAGAGGCCAAAACTTCCAGGTCTTAATGATCATGAACAAAGGCCTTGGCTCTAACGAAA
  GACTGGAGTTCATTGTCTCCACAGGGCCTTACCCCTCAGAGTCGGCCATGACGAAGGCTG
  TGTTTCCACTCTCCAATGGCAGTAGTGGTGGCTGGAGTGCGGTGCTTCAGGCCAGCAATG
  GCAATACTCTGACTATCAGCATCTCCAGTCCTGCCAGCGCACCCATAGGACGGTACACAA
  TGGCCCTCCAGATCTTCTCCCAGGGCGGCATCTCCTCTGTGAAACTTGGGACGTTCATAC
  TGCTTTTTAACCCCTGGCTGAATGTGGATAGCGTCTTTATGGGTAACCACGCTGAGAGAG
  AAGAGTATGTTCAGGAAGATGCCGGCATCATCTTTGTGGGAAGCACAAACCGAATTGGCA
  TGATTGGCTGGAACTTTGGACAGTTTGAAGAAGACATTCTCAGCATCTGCCTCTCAATCT
  TGGATAGGAGTCTGAATTTCCGCCGTGACGCTGCTACTGATGTGGCCAGCAGAAATGACC
  CCAAATACGTTGGCCGGGTGCTGAGTGCCATGATCAATAGCAATGATGACAATGGTGTGC
  TTGCTGGGAATTGGAGCGGCACTTACACCGGTGGCCGGGACCCAAGGAGCTGGAACGGCA
  GCGTGGAGATCCTCAAAAATTGGAAAAAATCTGGCTTCAGCCCAGTCCGATATGGCCAGT
  GCTGGGTCTTTGCTGGGACCCTCAACACAGCGCTGCGGTCTTTGGGGATTCCTTCCCGGG
  TGATCACCAACTTCAACTCAGCTCATGACACAGACCGAAATCTCAGTGTGGATGTGTACT
  ACGACCCCATGGGAAACCCCCTGGACAAGGGTAGTGATAGCGTATGGAATTTCCATGTCT
  GGAATGAAGGCTGGTTTGTGAGGTCTGACCTGGGCCCCTCGTACGGTGGATGGCAGGTGT
  TGGATGCTACCCCGCAGGAAAGAAGCCAAGGGGTGTTCCAGTGCGGCCCCGCTTCGGTCA
  TTGGTGTTCGAGAGGGTGATGTGCAGCTGAACTTCGACATGCCCTTTATCTTCGCGGAGG
  TTAATGCCGACCGCATCACCTGGCTGTACGACAACACCACTGGCAAACAGTGGAAGAATT
  CCGTGAACAGTCACACCATTGGCAGGTACATCAGCACCAAGGCGGTGGGCAGCAATGCTC
  GCATGGACGTCACGGACAAGTACAAGTACCCAGAAGGCTCTGACCAGGAAAGACAAGTGT
  TCCAAAAGGCTTTGGGGAAACTTAAACCCAACACGCCATTTGCCGCGACGTCTTCAATGG
  GTTTGGAAACAGAGGAACAGGAGCCCAGCATCATCGGGAAGCTGAAGGTCGCTGGCATGC
  TGGCAGTAGGCAAAGAAGTCAACCTGGTCCTACTGCTCAAAAACCTGAGCAGGGATACGA
  AGACAGTGACAGTGAACATGACAGCCTGGACCATCATCTACAACGGCACGCTTGTACATG
  AAGTGTGGAAGGACTCTGCCACAATGTCCCTGGACCCTGAGGAAGAGGCAGAACATCCCA
  TAAAGATCTCGTACGCTCAGTATGAGAAGTACCTGAAGTCAGACAACATGATCCGGATCA
  CAGCGGTGTGCAAGGTCCCAGATGAGTCTGAGGTGGTGGTGGAGCGGGACATCATCCTGG
  ACAACCCCACCTTGACCCTGGAGGTGCTGAACGAGGCTCGTGTGCGGAAGCCTGTGAACG
  TGCAGATGCTCTTCTCCAATCCACTGGATGAGCCGGTGAGGGACTGCGTGCTGATGGTGG
  AGGGAAGCGGCCTGCTGTTGGGTAACCTGAAGATCGACGTGCCGACCCTAGGGCCCAAGG
  AGCGGTCCCGGGTCCGTTTTGATATCCTGCCCTCCCGGAGTGGCACCAAGCAACTGCTCG
  CCGACTTCTCCTGCAACAAGTTCCCTGCAATCAAGGCCATGTTGTCCATCGATGTAGCCG
  AATGAAGGGCGCTGGTGGCCTCCCGTACAAACTTGGACAACACGGAGCAGGGAGAGCTCA
  CCATGGAATGAACCCCCCGCCCATGCTGTCCGGCCTGGGAAACCCTCTCCATCTCCCAAG
  GCTGCCAGACATGGACCTCCGGGCTCCAGCACATCCCCCTCTCCTCTCCCCCAGGTTGGG
  GCTGGGTCCACCCTGTCCTATGACTTGATCACTTTTGCACATTCCCTGGCCGCTTCTCCC
  CAGAGCTGCCTGCTCTGTGAGCCCCACAGCCCTGCTCATTCCTCACGCCCT
  
• Restriction Sites: Please inquire
• ACCN: NM_003245
• Insert Size: 2400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_003245.2.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003245.2, NP_003236.2
• RefSeq Size: 2616 bp
• RefSeq ORF: 2082 bp
• Locus ID: 7053
• Cytogenetics: 20p13
• Protein Families: Druggable Genome
• Gene Summary: 'Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008]'