LTBP4 (NM_003573) Human Untagged Clone

CAT#: SC303350

LTBP4 (untagged)-Human latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LTBP4
• Synonyms: ARCL1C; LTBP-4; LTBP4L; LTBP4S
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003573 edited
  ATGGGAGACGTAAAAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACGTCTAGGAGGA
  GCCGCTGCATCCGAGTCCCTGGCTGTCTCCGAAGCCTTCTGCAGGGTCCGAAGCTGCCAG
  CCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCAGTGCCTGCAGTGCCCAGTCCC
  AGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAG
  GCCAGAGCTCTACTGAAGCGGCGGCGGCCCCGGGGGCCAGGGGGCCGGGGACTACTGAGA
  AGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCGGTCCTGTGTCCCTTGATCTGT
  CACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGC
  AAGTTCTGCCAGTTGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTC
  ACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACGACGAGCACGGCGTGGCA
  TCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTG
  GAGCGTGTGTCTGGCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCG
  GCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCACAGAGCGCGCCGCGGGAG
  GACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAA
  TGCGCGTCCCCGCTGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTG
  GCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGGGGAACTCCGAAAGAGTG
  AGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGAT
  GTGGATGAGTGCGCGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGC
  GGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGTCCCGCAGCAGCTGCATC
  TCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGC
  TGTTCGCTGCCCATTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGC
  AAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCTCAGAGGGTTTCCGGGAG
  ATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGA
  CCCCTGGGCCAGGAGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACC
  TCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGCCCCGGCCTGAACCCCGG
  CCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCT
  GAGATTCCTGAATCAGGTCCCTCCTCCGGCATGTGTCAGCGCAACCCCCAGGTCTGCGGC
  CCAGGACGCTGCATTTCCCGGCCCAGCGGCTACACCTGCGCTTGCGACTCTGGCTTCCGG
  CTCAGCCCCCAGGGCACCCGATGCATTGATGTGGACGAATGTCGCCGCGTGCCCCCGCCC
  TGTGCTCCCGGGCGCTGCGAGAACTCACCAGGCAGCTTCCGCTGCGTGTGCGGCCCGGGC
  TTCCGAGCCGGCCCACGGGCTGCGGAATGCCTGGATGTGGACGAGTGCCACCGCGTGCCG
  CCGCCGTGTGACCTCGGGCGCTGCGAGAACACGCCAGGCAGCTTCCTGTGCGTGTGCCCC
  GCCGGGTACCAGGCTGCACCGCACGGAGCCAGCTGCCAGGATGTGGATGAATGCACCCAG
  AGCCCAGGCCTGTGTGGCCGAGGGGCCTGCAAGAACCTGCCTGGCTCTTTCCGCTGTGTT
  TGCCCGGCTGGCTTCCGGGGCTCGGCGTGTGAAGAGGATGTGGATGAGTGTGCCCAGGAG
  CCGCCGCCCTGTGGGCCCGGCCGCTGTGACAACACGGCAGGCTCCTTTCACTGTGCCTGC
  CCTGCTGGCTTCCGCTCCCGAGGGCCCGGGGCCCCCTGCCAAGATGTGGATGAGTGTGCC
  CGAAGCCCCCCACCCTGCACCTACGGCCGGTGTGAGAACACAGAAGGCAGCTTCCAGTGT
  GTCTGCCCCATGGGCTTCCAACCCAACACTGCTGGCTCCGAGTGCGAGGATGTGGATGAG
  TGTGAGAACCACCTCGCATGCCCTGGGCAGGAGTGTGTGAACTCGCCCGGCTCCTTCCAG
  TGCAGGACCTGTCCTTCTGGCCACCACCTGCACCGTGGCAGATGCACTGATGTGGACGAA
  TGCAGTTCGGGTGCCCCTCCCTGTGGTCCCCACGGCCACTGCACTAACACCGAAGGCTCC
  TTCCGCTGCAGCTGCGCGCCAGGCTACCGGGCGCCGTCGGGTCGGCCCGGGCCCTGCGCA
  GACGTGAACGAGTGCCTGGAGGGCGATTTCTGCTTCCCTCACGGCGAGTGCCTCAACACT
  GACGGCTCCTTTGCCTGTACTTGTGCCCCTGGCTACCGACCCGGACCCCGCGGAGCCTCT
  TGCCTCGACGTTGACGAGTGCAGCGAGGAGGACCTTTGCCAGAGCGGCATCTGTACCAAC
  ACCGACGGCTCCTTCGAGTGCATCTGTCCTCCGGGACACCGCGCTGGCCCGGACCTCGCC
  TCCTGCCTCGACGTGGACGAATGTCGCGAGCGAGGCCCAGCCCTGTGCGGGTCGCAGCGC
  TGTGAGAACTCTCCCGGCTCCTACCGCTGTGTCCGGGACTGCGATCCTGGGTACCACGCG
  GGCCCCGAGGGCACCTGTGACGATGTGGATGAGTGCCAAGAATATGGTCCCGAGATTTGT
  GGAGCCCAGCGTTGTGAGAACACCCCTGGCTCCTACCGCTGCACACCAGCCTGTGACCCT
  GGCTATCAGCCCACGCCAGGGGGCGGATGCCAGGATGTGGACGAATGCCGGAACCGGTCC
  TTCTGCGGTGCCCACGCCGTGTGCCAGAACCTGCCCGGCTCCTTCCAGTGCCTCTGTGAC
  CAGGGTTACGAGGGGGCACGGGATGGGCGTCACTGCGTGGATGTGAACGAGTGTGAAACA
  CTACAGGGTGTATGTGGAGCTGCCCTGTGTGAAAATGTCGAAGGCTCCTTCCTCTGTGTC
  TGCCCCAACAGCCCGGAAGAGTTTGACCCCATGACTGGACGCTGTGTTCCCCCACGAACT
  TCTGCTGGCACGTTCCCAGGCTCGCAGCCCCAGGCACCTGCTAGCCCCGTTCTGCCCGCC
  AGGCCACCTCCGCCACCCCTGCCCCGCCGACCCAGCACACCTAGGCAGGGCCCTGTGGGG
  AGTGGGCGCCGGGAGTGCTACTTTGACACAGCGGCCCCGGATGCATGTGACAACATCCTG
  GCTCGGAATGTGACATGGCAGGAGTGCTGCTGTACTGTGGGTGAGGGCTGGGGCAGCGGC
  TGCCGCATCCAGCAGTGCCCGGGCACCGAGACAGCTGAGTACCAGTCATTGTGCCCTCAC
  GGCCGGGGCTACCTGGCGCCCAGTGGAGACCTGAGCCTCCGGAGAGACGTGGACGAATGT
  CAGCTCTTCCGAGACCAGGTGTGCAAGAGTGGCGTGTGTGTGAACACGGCCCCGGGCTAC
  TCATGCTATTGCAGCAACGGCTACTACTACCACACACAGCGGCTGGAGTGCATCGACAAT
  GACGAGTGCGCCGATGAGGAACCGGCCTGTGAGGGCGGCCGCTGTGTCAACACTGTGGGC
  TCTTATCACTGTACCTGCGAGCCCCCACTGGTGCTGGATGGCTCGCAGCGCCGCTGCGTC
  TCCAACGAGAGCCAGAGCCTCGATGACAATCTGGGAGTGTGCTGGCAGGAAGTGGGGGCT
  GACCTCGTGTGCAGCCACCCTCGGCTGGACCGTCAGGCCACCTACACAGAGTGCTGCTGC
  CTGTATGGAGAGGCCTGGGGCATGGACTGCGCCCTCTGCCCTGCGCAGGACTCAGATGAC
  TTCGAGGCCCTGTGCAATGTGCTACGCCCCCCCGCATATAGCCCCCCGCGACCAGGTGGC
  TTTGGACTCCCCTACGAGTACGGCCCAGACTTAGGTCCACCTTACCAGGGCCTCCCATAT
  GGGCCTGAGTTGTACCCACCACCTGCGCTACCCTACGACCCCTACCCACCGCCACCTGGG
  CCCTTCGCCCGCCGGGAGGCTCCTTATGGGGCACCCCGCTTCGACATGCCAGACTTTGAG
  GACGATGGTGGCCCCTATGGCGAATCTGAGGCTCCTGCGCCACCTGGCCCGGGCACCCGC
  TGGCCCTATCGGTCCCGGGACACCCGCCGCTCCTTCCCAGAGCCCGAGGAGCCTCCTGAA
  GGTGGAAGCTATGCTGGTTCCCTGGCTGAGCCCTACGAGGAGCTGGAGGCGGAGGAGTGC
  GGGATCCTGGACGGCTGCACCAACGGCCGCTGCGTGCGCGTCCCCGAAGGCTTCACCTGC
  CGTTGCTTCGACGGCTACCGCCTGGACATGACCCGCATGGCCTGCGTTGACATCAACGAG
  TGTGATGAGGCCGAGGCTGCCTCCCCGCTGTGCGTCAACGCGCGTTGCCTCAACACGGAT
  GGCTCCTTCCGCTGCATCTGCCGCCCGGGATTCGCACCCACGCACCAGCCGCACCACTGT
  GCGCCCGCACGGCCCCGGGCCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_003573
• ORF Size: 5052 bp
• Insert Size: 5100
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003573.1, NP_003564.1
• RefSeq Size: 5054
• RefSeq ORF: 5052
• Locus ID: 8425
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.