IRS4 (NM_003604) Human Untagged Clone

CAT#: SC303356

IRS4 (untagged)-Human insulin receptor substrate 4 (IRS4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IRS4
• Synonyms: IRS-4; PY160
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003604 edited
  ATGGCGAGTTGCTCCTTCACTCGCGACCAAGCGACAAGAAGACTAAGAGGTGCAGCAGCG
  GCGGCAGCGGCAGCTCTAGCAGCAGTGGTGACCACCCCGCTTCTTTCCTCGGGAACCCCG
  ACCGCACTCATTGGGACCGGGTCGTCTTGTCCGGGAGCCATGTGGCTCTCCACGGCCACT
  GGCTCCCGGTCAGACTCCGAGTCCGAAGAGGAGGACCTGCCCGTCGGGGAGGAAGTCTGC
  AAACGCGGCTACCTGCGGAAACAGAAGCATGGGCACAGGCGCTACTTCGTGCTCAAACTC
  GAGACTGCTGACGCCCCAGCTCGGCTGGAATACTACGAAAATGCCAGGAAGTTCCGGCAC
  AGTGTCCGCGCCGCGGCGGCTGCAGCAGCGGCGGCCGCCTCTGGCGCCGCGATCCCCCCG
  CTCATTCCACCGCGGCGCGTGATCACCCTATACCAGTGCTTTTCCGTGAGCCAGCGAGCA
  GATGCAAGGTACCGACACCTCATTGCTCTTTTCACCCAAGACGAATACTTCGCGATGGTG
  GCCGAGAACGAGTCGGAGCAGGAAAGCTGGTACTTGCTGCTCAGCCGCCTCATCCTCGAG
  AGCAAGCGCCGCCGCTGCGGCACGCTCGGCGCGCAGCCGGACGGAGAGCCGGCCGCGCTG
  GCGGCGGCAGCGGCGGCGGAGCCACCCTTCTATAAAGATGTGTGGCAGGTAATAGTCAAA
  CCCAGGGGGCTGGGGCACAGAAAAGAGCTGAGCGGCGTGTTCCGGCTGTGTCTAACCGAC
  GAGGAGGTCGTGTTTGTGAGGCTGAACACCGAAGTGGCCAGCGTGGTCGTCCAGCTCCTG
  AGCATCCGTCGCTGTGGACACTCGGAGCAGTATTTCTTCTTGGAAGTAGGCAGGTCCACT
  GTCATCGGTCCGGGAGAGCTCTGGATGCAGGTCGATGACTGTGTGGTTGCCCAAAACATG
  CATGAGCTGTTTTTGGAGAAGATGAGAGCCTTGTGTGCAGACGAATACAGAGCCCGCTGC
  CGCAGCTACAGCATCAGCATCGGCGCCCACCTGTTAACCCTGCTGTCCGCTAGGAGGCAC
  CTGGGCTTGGTGCCGCTCGAGCCGGGAGGCTGGCTCAGAAGGTCCCGCTTTGAGCAGTTT
  TGCCACCTCAGGGCCATCGGCGACGGGGAAGACGAGATGCTTTTCACCAGGCGCTTCGTA
  ACACCCAGCGAGCCTGTGGCCCACTCCAGGCGAGGAAGACTGCACCTGCCCAGAGGGCGC
  AGGTCAAGGAGAGCGGTTTCAGTGCCGGCCAGCTTTTTTCGCCGCTTAGCACCCAGCCCA
  GCACGTCCCCGGCACCCTGCAGAAGCCCCGAACAATGGAGCTCGCCTGTCTTCTGAAGTG
  TCTGGTTCTGGCTCTGGCAACTTTGGGGAGGAAGGCAATCCCCAGGGCAAAGAAGATCAG
  GAAGGAAGCGGAGGTGACTACATGCCTATGAACAATTGGGGCTCAGGAAATGGCCGGGGC
  TCAGGAGGTGGCCAGGGCTCAAATGGCCAAGGCTCCAGTAGCCATAGCTCGGGAGGAAAC
  CAGTGTTCAGGCGAGGGACAGGGATCCCGAGGTGGTCAGGGCTCAAATGGCCAGGGCTCA
  GGAGGAAACCAGTGCTCTAGAGATGGCCAGGGCACCGCAGGTGGGCACGGTTCAGGTGGT
  GGCCAGAGACCTGGAGGTGGGCATGGCTCAGGTGGTGGCCAGGGACCTGGAGATGGCCAT
  GGCTCAGGTGGTGGCAAGAACTCTGGGGGGGGCAAAGGCTCAGGAAGTGGGAAAGGATCC
  GATGGTGATGGTGAACGTGGAAAATCTCTGAAGAAAAGATCCTATTTTGGCAAATTAACT
  CAAAGCAAGCAACAGCAAATGCCACCACCTCCACCACCTCCTCCTCCACCCCCACCAGCT
  GGAGGAACTGGTGGAAAAGGGAAGTCTGGGGGAAGATTCAGACTTTATTTTTGTGTTGAC
  AGAGGAGCCACGAAAGAATGCAAAGAAGCCAAAGAAGTGAAAGATGCAGAGATCCCAGAA
  GGTGCAGCTCGAGGTCCCCACAGAGCCAGAGCTTTTGATGAAGATGAGGATGACCCATAC
  GTGCCAATGAGGCCAGGGGTGGCCACCCCTCTTGTAAGCTCCAGTGATTATATGCCAATG
  GCTCCTCAAAATGTCTCTGCTTCAAAAAAGCGCCACTCTCGATCCCCTTTTGAAGATTCA
  AGAGGGTACATGATGATGTTTCCCAGAGTGAGCCCACCACCTGCTCCGAGTCCTCCAAAA
  GCACCTGATACTAATAAAGAGGATGACTCAAAGGACAATGACAGTGAGAGTGACTACATG
  TTTATGGCTCCTGGAGCCGGTGCAATTCCAAAAAACCCCAGAAATCCTCAGGGTGGCTCT
  TCCTCCAAAAGTTGGAGCTCCTACTTCTCTCTACCAAACCCTTTTCGGAGCTCACCTTTG
  GGACAGAATGACAACAGTGAGTATGTGCCAATGTTACCTGGAAAGTTCCTGGGGAGGGGC
  CTAGACAAAGAAGTCTCCTATAACTGGGACCCCAAAGATGCAGCTTCAAAGCCTTCAGGT
  GAGGGATCATTCTCAAAGCCTGGAGATGGGGGATCACCTTCAAAGCCTTCAGATCATGAG
  CCCCCAAAGAATAAAGCTAAGAGACCTAACCGACTTTCTTTTATTACAAAAGGATATAAA
  ATCAAGCCAAAACCACAAAAGCCCACACATGAGCAGAGAGAAGCTGACAGCTCTAGTGAC
  TACGTCAACATGGACTTCACTAAAAGAGAGAGCAATACACCAGCTCCCTCTACTCAAGGA
  CTACCAGATTCGTGGGGCATAATTGCTGAACCCAGACAGTCAGCCTTTTCTAATTATGTG
  AATGTTGAGTTTGGAGTGCCATTTCCAAATCCAGCAAACGACCTCTCAGATCTTTTAAGA
  GCTATACCACGTGCCAACCCCTTATCTCTGGACAGTGCTAGGTGGCCACTTCCTCCCCTT
  CCCCTCAGTGCTACAGGTAGCAATGCTATTGAGGAAGAGGGTGACTACATTGAAGTAATT
  TTCAACTCAGCAATGACACCAGCCATGGCTCTTGCTGACAGTGCCATTCGCTATGATGCT
  GAAACAGGTCGAATCTATGTGGTCGACCCATTTTCTGAGTGCTGTATGGATATTTCTCTC
  TCCCCCAGCCGATGTTCTGAACCACCACCTGTAGCTAGGCTGCTGCAGGAAGAAGAGCAG
  GAGAGAAGACGCCCACAAAGCCGTTCTCAAAGTTTCTTTGCAGCAGCCAGAGCCGCTGTC
  TCTGCTTTTCCAACAGACAGCCTCGAGAGAGACCTTTCCCCATCCTCAGCCCCGGCTGTC
  GCTTCGGCTGCAGAGCCGACTTTAGCCCTCAGCCAAGTTGTAGCTGCGGCCTCCGCGCTC
  GCCGCAGCCCCGGGCATCGGCGCAGCAGCCGCAGCTGCTGGATTTGACTCCGCCTCTGCC
  CGCTGGTTTCAACCTGTTGCTAATGCTGCTGATGCCGAAGCAGTAAGGGGAGCCCAAGAC
  GTTGCCGGTGGCTCGAACCCTGGAGCCCACAACCCATCTGCAAACCTTGCCAGAGGTGAT
  AACCAGGCTGGCGGGGCTGCCGCTGCAGCTGCCGCTCCGGAACCACCACCTCGCAGTCGC
  CGGGTGCCAAGACCCCCGGAGAGAGAAGATTCTGACAACGACGACGACACTCACGTGAGA
  ATGGATTTTGCCAGACGTGATAATCAGTTCGACTCTCCCAAAAGAGGTCGGTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003604 unedited
  CGTCACATTTGTATACCATCATATAGGCGGCCGCGAATTCGCCCTTGTCCTCGCTCACCT
  TAAAACCATCGTGCATCACCATGGCGAGTTGCTCCTTCACTCGCGACCAAGCGACAAGAA
  GACTAAGAGGTGCAGCAGCGGCGGCAGCGGCAGCTCTAGCAGCAGTGGTGACCACCCCGC
  TTCTTTCCTCGGGAACCCCGACCGCACTCATTGGGACCGGGTCGTCTTGTCCGGGAGCCA
  TGTGGCTCTCCACGGCCACTGGCTCCCGGTCAGACTCCGAGTCCGAAGAGGAGGACCTGC
  CCGTCGGGGAGGAAGTCTGCAAACGCGGCTACCTGCGGAAACAGAAGCATGGGCACAGGC
  GCTACTTCGTGCTCAAACTCGAGACTGCTGACGCCCCAGCTCGGCTGGAATACTACGAAA
  ATGCCAGGAAGTTCCGGCACAGTGTCCGCGCCGCGGCGGCTGCAGCAGCGGCGGCCGCCT
  CTGGCGCCGCGATCCCCCCGCTCATTCCACCGCGGCGCGTGATCACCCTATACCAGTGCT
  TTTCCGTGAGCCAGCGAGCAGATGCAAGGTACCGACACCTCATTGCTCTTTTCACCCAAG
  ACGAATACTTCGCGATGGTGGCCGAGAACGAGTNCGAGCAGGAAAGCTGGTACTTGCTGC
  TCAGCCGCCTCATCCTCGAGAGCAAGCGCCGNCGCTGCGGCACGCTCGGCGCGCAGCCCG
  ACGGAGAGCCGGCCGNCGCTGCNGCNGCAGCGGCGGCGGAGCCACCCTTCATAAAGATGT
  GTTGCAGGTAATAGTCAAACCCAGGGGGCTGGGGCACAGAAAAGAGCTGAGCGNCGTGGT
  CCGGCTGGGTCTAACCGACGAAGAAGTTTGTGTTTGG
  
• Restriction Sites: Please inquire
• ACCN: NM_003604
• ORF Size: 3774 bp
• Insert Size: 5000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_003604.1, NP_003595.1
• RefSeq Size: 3939
• RefSeq ORF: 3774
• Locus ID: 8471
• Protein Families: Druggable Genome
• Protein Pathways: Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus
• Gene Summary: IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008]