PTPD2 (PTPN14) (NM_005401) Human Untagged Clone

CAT#: SC303636

PTPN14 (untagged)-Human protein tyrosine phosphatase, non-receptor type 14 (PTPN14)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPN14
• Synonyms: CATLPH; PEZ; PTP36
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005401, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCTTTTGGTCTGAAGCTCCGCCGGACACGGCGCTACAACGTCCTGAGCAAGAACTGCTTTGTCACAC
  GGATTCGCCTGCTGGACAGCAATGTTATCGAGTGCACGCTGTCGGTGGAAAGCACAGGGCAAGAATGCCT
  GGAGGCTGTGGCCCAGAGGCTGGAGCTGCGAGAGACGCACTACTTTGGCCTTTGGTTTCTCAGCAAGAGC
  CAGCAAGCACGATGGGTGGAGCTGGAGAAACCTCTGAAGAAACATCTGGACAAATTCGCTAATGAGCCTT
  TGCTTTTCTTTGGAGTCATGTTCTATGTGCCAAATGTGTCATGGCTTCAGCAAGAGGCCACAAGATATCA
  GTATTACCTGCAAGTCAAAAAAGATGTGCTTGAAGGGCGATTACGATGTACATTGGACCAGGTGATTCGG
  CTAGCCGGCCTAGCTGTGCAAGCTGATTTTGGAGACTATAATCAGTTTGATTCTCAAGATTTCCTCAGAG
  AGTATGTGCTATTTCCTATGGATTTGGCCCTGGAAGAGGCTGTTCTGGAGGAGCTGACCCAGAAGGTAGC
  CCAAGAACACAAAGCCCACAGTGGAATCCTGCCAGCAGAAGCTGAACTGATGTACATCAATGAAGTTGAA
  CGTTTGGATGGATTTGGACAGGAAATCTTCCCTGTAAAGGACAATCATGGAAACTGTGTACACCTTGGCA
  TTTTCTTTATGGGGATTTTCGTGAGGAACAGAATTGGAAGACAAGCGGTAATATACAGGTGGAATGACAT
  GGGGAATATCACTCATAACAAGTCGACCATTCTAGTGGAGCTCATCAACAAAGAAGAGACTGCCCTCTTT
  CACACGGATGATATCGAAAATGCCAAGTATATTTCTCGGTTGTTTGCCACACGACACAAGTTTTACAAAC
  AAAACAAAATCTGCACTGAACAGTCAAATTCTCCACCCCCCATCAGACGCCAGCCCACCTGGAGCCGATC
  CTCTCTGCCCAGGCAGCAGCCGTACATCCTGCCTCCCGTTCACGTCCAGTGTGGTGAGCACTACTCGGAA
  ACGCACACCTCGCAAGACAGCATTTTTCATGGGAATGAAGAAGCCTTGTATTGCAACTCTCACAACAGCC
  TGGACTTAAATTATTTAAATGGCACTGTCACCAATGGCAGCGTGTGTAGCGTTCACAGCGTCAACTCCCT
  CAACTGCTCGCAAAGTTTCATCCAGGCCTCCCCTGTATCCTCCAACCTCAGTATCCCTGGGAGTGACATC
  ATGCGGGCCGACTACATCCCGAGCCACCGGCACAGCGCGATCATCGTGCCCTCGTACAGGCCAACCCCCG
  ATTATGAGACAGTCATGCGCCAGATGAAGAGGGGGATCCTGCATACAGACAGCCAGAGCCAGTCTCTGAG
  AAACCTCAACATTATCAACACCCATGCCTACAACCAGCCAGAGGATCTGGTGTACAGCCAACCGGAGATG
  CGGGAGAGGCACCCCTACACTGTCCCTTATGGGCCACAGGGGGTCTACAGCAACAAACTTGTCAGTCCAT
  CTGACCAGAGGAACCCAAAGAATAATGTGGTACCAAGCAAGCCGGGGGCAAGCGCCATCTCGCACACGGT
  GAGCACCCCAGAGCTGGCCAACATGCAGCTGCAGGGCAGCCATAACTACAGCACGGCCCACATGCTTAAG
  AACTATCTCTTCAGGCCACCGCCCCCCTACCCACGGCCACGACCTGCCACCAGCACCCCAGACCTGGCCA
  GCCACCGCCACAAGTACGTCAGCGGCAGCAGCCCGGACCTGGTGACCCGGAAGGTGCAGCTCTCGGTGAA
  GACCTTCCAAGAGGACAGCTCTCCGGTGGTTCATCAGTCTCTCCAGGAGGTGAGCGAGCCCCTCACGGCC
  ACCAAGCACCACGGCACTGTGAACAAGCGCCACAGCCTGGAGGTGATGAACAGCATGGTGCGGGGCATGG
  AGGCCATGACGCTCAAGTCGCTCCACCTCCCCATGGCTCGCCGCAACACGCTCCGGGAGCAGGGACCGCC
  CGAGGAGGGGTCAGGCAGCCACGAGGTCCCCCAGCTCCCTCAGTATCACCACAAGAAGACCTTCTCTGAT
  GCCACTATGCTAATCCACAGCAGCGAGAGTGAGGAGGAGGAGGAGGAGGCTCCAGAATCGGTGCCCCAGA
  TCCCCATGCTCCGGGAGAAGATGGAGTACAGTGCCCAGCTGCAGGCGGCCCTGGCCCGCATCCCCAACAA
  GCCCCCGCCTGAGTACCCCGGTCCAAGGAAGAGTGTGAGCAATGGGGCTCTGAGGCAGGACCAAGCCAGC
  CTTCCTCCCGCCATGGCCAGAGCCAGGGTGCTGAGGCATGGGCCAGCCAAGGCCATCAGCATGTCTCGGA
  CTGACCCGCCGGCTGTCAACGGGGCCTCTCTCGGCCCATCCATCTCGGAACCCGACCTGACTAGTGTGAA
  GGAGCGGGTCAAAAAAGAGCCTGTGAAGGAGAGACCTGTGTCTGAAATGTTTTCCCTGGAAGACAGCATT
  ATAGAGAGAGAGATGATGATCAGGAATCTAGAGAAGCAGAAGATGGCAGGCCTGGAGGCACAGAAGAGGC
  CGCTGATGTTGGCAGCATTGAATGGGCTCTCGGTGGCTCGAGTCTCAGGGCGGGAAGAGAATCGAGTTGA
  TGCCACCCGGGTTCCCATGGACGAGAGGTTCAGAACCCTGAAGAAGAAACTAGAAGAGGGAATGGTGTTC
  ACAGAATATGAGCAAATTCCAAAGAAAAAGGCGAATGGCATTTTCAGCACAGCAGCTCTGCCAGAAAACG
  CCGAGCGCAGCCGAATCCGTGAAGTTGTCCCCTATGAGGAGAATCGAGTAGAGCTGATACCAACCAAAGA
  AAATAACACAGGATACATTAATGCCTCCCACATCAAGGTGGTGGTTGGCGGGGCAGAATGGCACTACATA
  GCCACCCAGGGGCCCCTGCCACACACGTGCCACGACTTCTGGCAGATGGTGTGGGAGCAGGGAGTGAATG
  TGATTGCCATGGTCACTGCAGAGGAGGAGGGTGGACGAACCAAAAGCCACCGATACTGGCCCAAACTAGG
  TTCAAAGCACAGCTCAGCCACCTATGGCAAGTTCAAGGTCACCACGAAGTTTCGAACGGATTCTGTTTGC
  TATGCAACCACGGGCTTGAAGGTCAAGCACCTTTTGTCTGGGCAAGAAAGGACGGTGTGGCATTTACAAT
  ATACTGACTGGCCAGATCACGGCTGTCCAGAAGATGTCCAAGGATTTTTATCCTACTTGGAGGAGATCCA
  GTCGGTCCGTCGCCATACCAACAGCATGCTGGAAGGCACCAAGAACCGGCACCCGCCCATCGTGGTCCAC
  TGTAGTGCTGGGGTGGGAAGGACCGGCGTGCTCATTCTTTCTGAGCTGATGATCTACTGCTTGGAACATA
  ACGAAAAGGTGGAAGTGCCCATGATGCTGAGGCTCCTCAGGGAGCAGAGGATGTTCATGATCCAGACTAT
  CGCTCAGTACAAGTTTGTCTACCAAGTCCTCATCCAGTTCCTCCAAAACTCCAGACTCATTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_005401
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005401.4, NP_005392.2
• RefSeq Size: 13443 bp
• RefSeq ORF: 3564 bp
• Locus ID: 5784
• Cytogenetics: 1q32.3-q41
• Protein Families: Druggable Genome
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]'