PTPRU (NM_005704) Human Untagged Clone

CAT#: SC303684

PTPRU (untagged)-Human protein tyrosine phosphatase, receptor type, U (PTPRU), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRU
• Synonyms: FMI; hPTP-J; PCP-2; PTP; PTP-J; PTP-PI; PTP-RO; PTPPSI; PTPRO; PTPU2; R-PTP-PSI; R-PTP-U
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005704, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGG
  CAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGA
  TGACTTCCAGTGGGAGCAAGTGCGAATCCACCCTGGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCC
  TACTTGATGGTCAACACTTCCCAGCATGCCCCAGGCCAGCGAGCCCATGTCATCTTCCAGAGCCTGAGCG
  AGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCCCGGGCACCCT
  GGGCGTCTACGTGCGCGTTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGC
  CGTCAGTGGCACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAATGAATATCAGGTGCTGTTTGAGG
  CCCTCATCTCCCCAGACCGCAGGGGCTACATGGGCCTAGATGACATCCTGCTTCTCAGCTACCCCTGCGC
  AAAGGCCCCACACTTCTCCCGCCTGGGCGACGTGGAGGTCAACGCGGGCCAGAACGCGTCGTTCCAGTGC
  ATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCCTCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGG
  CGGCGGGCGTGCGGCACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCGCGC
  CGAGCAGGACCTGTACCGCTGTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTC
  ATCGTCAAGGAGCCCCCAACTCCCATCGCGCCCCCACAGCTGCTGCGTGCTGGCCCCACCTACCTCATCA
  TCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTGAGTACCGCATGGC
  GCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACCCCGAC
  ACAGAGTATGAGATCAGCGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCC
  TCATCAGCCGCACCAAATGCGCAGAGCCCATGAGGGCCCCCAAAGGCCTGGCTTTTGCTGAGATCCAGGC
  CCGTCAGCTGACCCTGCAGTGGGAACCACTGGGCTACAACGTGACGCGTTGCCACACCTATACTGTGTCG
  CTGTGCTATCACTACACCCTGGGCAGCAGCCACAACCAGACCATCCGAGAGTGTGTGAAGACAGAGCAAG
  GTGTCAGCCGCTACACCATCAAGAACCTGCTGCCCTATCGGAACGTTCACGTGAGGCTTGTCCTCACTAA
  CCCTGAGGGGCGCAAAGAGGGCAAGGAGGTCACTTTCCAGACGGATGAGGATGTGCCCAGTGGGATTGCA
  GCCGAGTCCCTGACCTTCACTCCACTGGAGGACATGATCTTCCTCAAGTGGGAGGAGCCCCAGGAGCCCA
  ATGGTCTCATCACCCAGTATGAGATCAGCTACCAGAGCATCGAGTCATCAGACCCGGCAGTGAACGTGCC
  AGGCCCACGACGTACCATCTCCAAGCTCCGCAATGAGACCTACCATGTCTTCTCCAACCTGCACCCAGGC
  ACCACCTACCTGTTCTCCGTGCGGGCCCGCACAGGCAAAGGCTTCGGCCAGGCGGCACTCACTGAGATAA
  CCACTAACATCTCTGCTCCCAGCTTTGATTATGCCGACATGCCGTCACCCCTGGGCGAGTCTGAGAACAC
  CATCACCGTGCTGCTGAGGCCGGCACAGGGCCGCGGTGCGCCCATCAGTGTGTACCAGGTGATTGTGGAG
  GAGGAGCGGGCGCGGAGGCTGCGGCGGGAGCCAGGTGGACAGGACTGCTTCCCAGTGCCATTGACCTTCG
  AGGCGGCGCTGGCCCGAGGCCTGGTGCACTACTTCGGGGCCGAACTGGCGGCCAGCAGTCTACCTGAGGC
  CATGCCCTTTACCGTGGGTGACAACCAGACCTACCGAGGCTTCTGGAACCCACCACTTGAGCCTAGGAAG
  GCCTATCTCATCTACTTCCAGGCAGCAAGCCACCTGAAGGGGGAGACCCGGCTGAATTGCATCCGCATTG
  CCAGGAAAGCTGCCTGCAAGGAAAGCAAGCGGCCCCTGGAGGTGTCCCAGAGATCGGAGGAGATGGGGCT
  TATCCTGGGCATCTGTGCAGGGGGGCTTGCTGTCCTCATCCTTCTCCTGGGTGCCATCATTGTCATCATC
  CGCAAAGGGAGAGACCACTATGCCTACTCCTACTACCCGAAGCCGGTGAACATGACCAAGGCCACCGTCA
  ACTACCGCCAGGAGAAGACACACATGATGAGCGCCGTGGACCGCAGCTTCACAGACCAGAGCACCCTGCA
  GGAGGACGAGCGGCTGGGCCTGTCCTTCATGGACACCCATGGCTACAGCACCCGGGGAGACCAGCGCAGC
  GGTGGGGTCACTGAGGCCAGCAGCCTCCTGGGGGGCTCCCCGAGGCGTCCCTGTGGCCGGAAGGGCTCCC
  CATACCACACGGGGCAGCTGCACCCTGCGGTGCGTGTCGCAGACCTTCTGCAGCACATCAACCAGATGAA
  GACGGCCGAGGGTTACGGCTTCAAGCAGGAGTATGAGAGCTTCTTTGAAGGCTGGGACGCCACAAAGAAG
  AAAGACAAGGTCAAGGGCAGCCGGCAGGAGCCAATGCCTGCCTATGATCGGCACCGAGTGAAACTGCACC
  CGATGCTGGGAGACCCCAATGCCGACTACATTAATGCCAACTACATAGATGGTTACCACAGGTCAAACCA
  CTTCATAGCCACTCAAGGGCCGAAGCCTGAGATGGTCTATGACTTCTGGCGTATGGTGTGGCAGGAGCAC
  TGTTCCAGCATCGTCATGATCACCAAGCTGGTCGAGGTGGGCAGGGTGAAATGCTCACGGTACTGGCCGG
  AGGACTCAGACACCTACGGGGACATCAAGATTATGCTGGTGAAGACAGAGACCCTGGCTGAGTATGTCGT
  GCGCACTTTTGCCCTGGAGCGGAGAGGCTACTCTGCCCGGCACGAGGTCCGCCAGTTCCACTTCACAGCG
  TGGCCAGAGCATGGCGTCCCCTACCATGCCACGGGGCTGCTGGCTTTCATCCGGCGCGTGAAGGCCTCCA
  CCCCACCTGATGCCGGGCCCATTGTCATCCACTGCAGCGCGGGCACCGGCCGCACAGGTTGCTATATCGT
  CCTGGATGTGATGCTGGACATGGCAGAGTGTGAGGGCGTCGTGGACATTTACAACTGTGTGAAGACTCTC
  TGCTCCCGGCGTGTCAACATGATCCAGACTGAGGAGCAGTACATCTTCATTCATGATGCAATCCTGGAGG
  CCTGCCTGTGTGGGGAGACCACCATCCCTGTCAGTGAGTTCAAGGCCACCTACAAGGAGATGATCCGCAT
  TGATCCTCAGAGTAATTCCTCCCAGCTGCGGGAAGAGTTCCAGACGCTGAACTCGGTCACCCCGCCGCTG
  GACGTGGAGGAGTGCAGCATCGCCCTGTTGCCCCGGAACCGCGACAAGAACCGCAGCATGGACGTCCTGC
  CGCCCGACCGCTGCCTGCCCTTCCTCATCTCCACTGATGGGGACTCCAACAACTACATTAATGCAGCCCT
  GACTGACAGCTACACACGGAGTGCGGCCTTCATCGTGACCCTGCACCCGCTGCAGAGCACCACGCCCGAC
  TTCTGGCGGCTGGTCTACGATTACGGGTGCACCTCCATCGTCATGCTCAACCAGCTGAACCAGTCCAACT
  CCGCCTGGCCCTGCCTGCAGTACTGGCCAGAGCCAGGCCGGCAGCAATATGGCCTCATGGAGGTGGAGTT
  TATGTCGGGCACAGCTGATGAAGACTTAGTGGCTCGAGTCTTCCGGGTGCAGAACATCTCTCGGTTGCAG
  GAGGGGCACCTGCTGGTGCGGCACTTCCAGTTCCTGCGCTGGTCTGCATACCGGGACACACCTGACTCCA
  AGAAGGCCTTCTTGCACCTGCTGGCTGAGGTGGACAAGTGGCAGGCCGAGAGTGGGGATGGGCGCACCAT
  CGTGCACTGCCTAAACGGGGGAGGACGCAGCGGCACCTTCTGCGCCTGCGCCACGGTCCTGGAGATGATC
  CGCTGCCACAACTTGGTGGACGTTTTCTTTGCTGCCAAAACCCTCCGGAACTACAAACCCAACATGGTGG
  AGACCATGGATCAGTACCACTTTTGCTACGATGTGGCCCTGGAGTACTTGGAGGGGCTGGAGTCAAGATA
  G
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_005704
• ORF Size: 4341 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005704.4, NP_005695.3
• RefSeq Size: 5632
• RefSeq ORF: 4341
• Locus ID: 10076
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).