MRC2 (NM_006039) Human Untagged Clone

CAT#: SC303722

MRC2 (untagged)-Human mannose receptor, C type 2 (MRC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MRC2
• Synonyms: CD280; CLEC13E; ENDO180; UPARAP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006039, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGCCCGGCCGGCCGGCCCCCGCGCCCTGGCCTCGTCACCTGCTGCGCTGCGTCCTGCTCCTCGGGT
  GCCTGCACCTCGGCCGTCCCGGCGCCCCTGGGGACGCCGCCCTCCCGGAACCCAACGTCTTCCTCATCTT
  CAGCCATGGACTGCAGGGCTGCCTGGAGGCCCAGGGCGGGCAGGTCAGAGTCACCCCGGCTTGCAATACC
  AGCCTCCCTGCCCAGCGCTGGAAGTGGGTCTCCCGAAACCGGCTATTCAACCTGGGTACCATGCAGTGCC
  TGGGCACAGGCTGGCCAGGCACCAACACCACGGCCTCCCTGGGCATGTATGAGTGTGACCGGGAAGCACT
  GAATCTTCGCTGGCATTGTCGTACACTGGGTGACCAGCTGTCCTTGCTCCTGGGGGCCCGCACCAGCAAC
  ATATCCAAGCCTGGCACCCTTGAGCGTGGTGACCAGACCCGCAGTGGCCAGTGGCGCATCTACGGCAGCG
  AGGAGGACCTATGTGCTCTGCCCTACCACGAGGTCTACACCATCCAGGGAAACTCCCACGGAAAGCCGTG
  CACCATCCCCTTCAAATATGACAACCAGTGGTTCCACGGCTGCACCAGCACGGGCCGCGAGGATGGTCAC
  CTGTGGTGTGCCACCACCCAGGACTACGGCAAAGACGAGCGCTGGGGCTTCTGCCCCATCAAGAGTAACG
  ACTGCGAGACCTTCTGGGACAAGGACCAGCTGACTGACAGCTGCTACCAGTTTAACTTCCAGTCCACGCT
  GTCGTGGAGGGAGGCCTGGGCCAGCTGCGAGCAGCAGGGTGCGGATCTGCTGAGCATCACGGAGATCCAC
  GAGCAGACCTACATCAACGGCCTCCTCACTGGGTACAGCTCCACCCTGTGGATCGGCTTGAATGACTTGG
  ACACGAGCGGAGGCTGGCAGTGGTCGGACAACTCGCCCCTCAAGTACCTCAACTGGGAGAGTGACCAGCC
  GGACAACCCCAGTGAGGAGAACTGTGGAGTGATCCGCACTGAGTCCTCGGGCGGCTGGCAGAACCGTGAC
  TGCAGCATCGCGCTGCCCTATGTGTGCAAGAAGAAGCCCAACGCCACGGCCGAGCCCACCCCTCCAGACA
  GGTGGGCCAATGTGAAGGTGGAGTGCGAGCCGAGCTGGCAGCCCTTCCAGGGCCACTGCTACCGCCTGCA
  GGCCGAGAAGCGCAGCTGGCAGGAGTCCAAGAAGGCATGTCTACGGGGCGGTGGCGACCTGGTCAGCATC
  CACAGCATGGCGGAGCTGGAATTCATCACCAAGCAGATCAAGCAAGAGGTGGAGGAGCTGTGGATCGGCC
  TCAACGATTTGAAACTGCAGATGAATTTTGAGTGGTCTGACGGGAGCCTTGTGAGCTTCACCCACTGGCA
  CCCCTTTGAGCCCAACAACTTCCGGGACAGTCTGGAGGACTGTGTCACCATCTGGGGCCCGGAAGGCCGC
  TGGAACGACAGTCCCTGTAACCAGTCCTTGCCATCCATCTGCAAGAAGGCAGGCCAGCTGAGCCAGGGGG
  CCGCCGAGGAGGACCATGGCTGCCGGAAGGGTTGGACGTGGCACAGCCCATCCTGCTACTGGCTGGGAGA
  AGACCAAGTGACCTACAGTGAGGCCCGGCGCCTGTGCACTGACCATGGCTCTCAGCTGGTCACCATCACC
  AACAGGTTCGAGCAGGCCTTCGTCAGCAGCCTCATCTACAACTGGGAGGGCGAGTACTTCTGGACGGCCC
  TGCAGGACCTCAACAGCACCGGCTCCTTCTTCTGGCTCAGTGGGGATGAAGTCATGTACACCCACTGGAA
  CCGGGACCAGCCCGGGTACAGCCGTGGGGGCTGCGTGGCGCTGGCCACTGGCAGCGCCATGGGGCTGTGG
  GAGGTGAAGAACTGTACCTCGTTCCGGGCCCGCTACATCTGCCGGCAGAGCCTGGGCACTCCAGTGACGC
  CGGAGCTGCCGGGGCCAGATCCCACGCCCAGCCTCACTGGCTCCTGTCCCCAGGGCTGGGCCTCGGACAC
  CAAACTCCGGTATTGCTATAAGGTGTTCAGCTCAGAGCGGCTGCAGGACAAGAAGAGCTGGGTCCAGGCC
  CAGGGGGCCTGCCAGGAGCTGGGGGCCCAGCTGCTGAGCCTGGCCAGCTACGAGGAGGAGCACTTTGTGG
  CCAACATGCTCAACAAGATCTTCGGTGAATCAGAACCCGAGATCCACGAGCAGCACTGGTTCTGGATCGG
  CCTGAACCGTCGGGATCCCAGAGGGGGTCAGAGTTGGCGCTGGAGCGACGGCGTAGGGTTCTCTTACCAC
  AATTTCGACCGGAGCCGGCACGACGACGACGACATCCGAGGCTGTGCGGTGCTGGACCTGGCCTCCCTGC
  AGTGGGTGGCCATGCAGTGCGACACACAGCTGGACTGGATCTGCAAGATCCCCAGAGGTACGGACGTGCG
  GGAGCCCGACGACAGCCCTCAAGGCCGACGGGAATGGCTGCGCTTCCAGGAGGCCGAGTACAAGTTCTTT
  GAGCACCACTCCACGTGGGCGCAGGCGCAGCGCATCTGCACGTGGTTCCAGGCCGAGCTGACCTCGGTGC
  ACAGCCAGGCGGAGCTAGACTTCCTGAGCCACAACTTGCAGAAGTTCTCCCGGGCCCAGGAGCAGCACTG
  GTGGATCGGCCTGCACACCTCTGAGAGCGATGGGCGCTTCAGATGGACAGATGGTTCCATTATAAACTTC
  ATCTCCTGGGCACCAGGCAAACCTCGGCCTGTCGGCAAGGACAAGAAGTGCGTGTACATGACAGCCAGCC
  GAGAGGACTGGGGGGACCAGAGGTGCCTGACAGCCTTGCCCTACATCTGCAAGCGCAGCAACGTCACCAA
  AGAAACGCAGCCCCCAGACCTGCCAACTACAGCCCTGGGGGGCTGCCCCTCTGACTGGATCCAGTTCCTC
  AACAAGTGTTTTCAGGTCCAGGGCCAGGAACCCCAGAGCCGGGTGAAGTGGTCAGAGGCACAGTTCTCCT
  GTGAACAGCAAGAGGCCCAGCTGGTCACCATCACAAACCCCTTAGAGCAAGCATTCATCACAGCCAGCCT
  GCCCAATGTGACCTTTGACCTTTGGATTGGCCTCCATGCCTCGCAGAGGGACTTCCAGTGGGTGGAGCAG
  GAGCCTTTGATGTATGCCAACTGGGCACCTGGGGAGCCCTCTGGCCCTAGCCCTGCTCCCAGTGGCAACA
  AACCGACCAGCTGTGCAGTGGTCCTGCACAGCCCCTCAGCCCACTTCACTGGCCGCTGGGACGATCGGAG
  CTGCACGGAGGAGACCCATGGCTTCATCTGCCAGAAGGGCACGGACCCCTCCCTGAGCCCGTCCCCAGCA
  GCGCTGCCCCCCGCCCCGGGCACTGAGCTCTCCTACCTCAACGGCACCTTCCGGCTGCTTCAGAAGCCGC
  TGCGCTGGCACGATGCCCTCCTGCTGTGTGAGAGCCGCAATGCCAGCCTGGCCTACGTGCCCGACCCCTA
  CACCCAGGCCTTCCTCACGCAGGCTGCCCGAGGGCTGCGCACGCCGCTCTGGATTGGGCTGGCTGGCGAG
  GAGGGCTCTCGGCGGTACTCCTGGGTCTCAGAGGAGCCGCTGAACTACGTGGGCTGGCAGGACGGGGAGC
  CGCAGCAGCCGGGGGGCTGTACCTACGTAGATGTGGACGGGGCCTGGCGCACCACCAGCTGTGACACCAA
  GCTGCAGGGGGCTGTGTGTGGGGTTAGCAGTGGGCCCCCTCCTCCCCGAAGAATAAGCTACCATGGCAGC
  TGTCCCCAGGGACTGGCAGACTCCGCGTGGATTCCCTTCCGGGAGCACTGCTATTCTTTCCACATGGAGC
  TGCTGCTGGGCCACAAGGAGGCGCGACAGCGCTGCCAGAGAGCGGGTGGGGCCGTCCTGTCTATCCTGGA
  TGAGATGGAGAATGTGTTTGTCTGGGAGCACCTGCAGAGCTATGAGGGCCAGAGTCGGGGCGCCTGGCTG
  GGCATGAACTTCAACCCCAAAGGAGGCACTCTGGTCTGGCAGGACAACACAGCTGTGAACTACTCCAACT
  GGGGGCCCCCGGGCTTGGGCCCCAGCATGCTGAGCCACAACAGCTGCTACTGGATTCAGAGCAACAGCGG
  GCTATGGCGCCCCGGCGCTTGCACCAACATCACCATGGGTGTCGTCTGCAAGCTTCCTCGTGCTGAGCAG
  AGCAGCTTCTCCCCATCAGCGCTTCCAGAGAACCCAGCGGCCCTGGTGGTGGTGCTGATGGCGGTGCTGC
  TGCTCCTGGCCTTGCTGACCGCAGCCCTCATCCTTTACCGGAGGCGCCAGAGCATCGAGCGCGGGGCCTT
  TGAGGGTGCCCGCTACAGCCGCAGCAGCTCCAGCCCCACCGAGGCCACTGAGAAGAACATCCTGGTGTCA
  GACATGGAAATGAATGAGCAACAAGAATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_006039
• ORF Size: 4440 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006039.4, NP_006030.2
• RefSeq Size: 6004
• RefSeq ORF: 4440
• Locus ID: 9902
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]