SLC16A2 (NM_006517) Human Untagged Clone

CAT#: SC303783

SLC16A2 (untagged)-Human solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (SLC16A2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC16A2
• Synonyms: AHDS; DXS128; DXS128E; MCT 7; MCT7; MCT 8; MCT8; MRX22; XPCT
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_006517 edited
  ATGGGGAGAGGAGGAGGGGGGTTGGACGTGGGAGGAGGAGGAGAGGGCTCGAGGGACCGT
  CTGTCGCGGGACGGGCTGGCCAGCTGGGGCGCGGAGCCTGGAGGAGGAGGCAGCGGCAGC
  GGCAGCAGCAGCCCTCCGAGCAGCAGCAGCTGCAGCAGCAGAAACAAGTACCAGCCACAA
  AGCGGCTCCTCTGGCCCAAGCAGCCACAGTCCCCCCGCCGCGATGGCGCTGCAAAGCCAG
  GCGAGCGAGGAAGCAAAGGGGCCCTGGCAGGAGGCAGACCAGGAACAGCAGGAGCCGGTG
  GGTAGCCCAGAGCCGGAGTCTGAGCCGGAGCCTGAGCCCGAGCCCGAGCCCGTGCCAGTG
  CCCCCGCCCGAGCCCCAGCCGGAGCCCCAGCCCCTACCGGACCCCGCACCCCTGCCGGAG
  CTGGAGTTCGAGTCCGAGCGGGTGCACGAACCCGAGCCCACGCCTACGGTAGAGACCCGC
  GGCACCGCGCGCGGCTTCCAGCCTCCCGAAGGTGGCTTCGGCTGGGTGGTGGTGTTCGCT
  GCCACCTGGTGCAACGGCTCCATCTTCGGCATCCATAACTCTGTCGGGATCCTCTACTCC
  ATGCTGCTAGAGGAGGAAAAGGAAAAAAATCGCCAAGTGGAGTTCCAAGCAGCATGGGTC
  GGAGCCCTCGCGATGGGTATGATCTTCTTCTGTTCTCCCATTGTGAGTATATTCACTGAC
  CGTTTGGGCTGCCGAATCACAGCAACCGCGGGGGCTGCCGTTGCTTTCATTGGCCTCCAT
  ACCAGCTCCTTCACCAGCTCCCTAAGCCTGCGCTACTTCACCTACGGGATTCTCTTTGGT
  TGTGGCTGTTCCTTCGCCTTTCAGCCATCCCTCGTCATCCTGGGCCACTACTTTCAACGC
  CGCCTGGGTCTGGCCAATGGTGTGGTGTCTGCTGGGAGTAGCATTTTCTCCATGTCCTTC
  CCCTTCCTCATCAGAATGCTGGGGGATAAGATCAAGCTGGCCCAAACCTTCCAGGTGCTG
  AGTACCTTCATGTTTGTTCTTATGCTGCTTTCACTCACCTACCGGCCCCTCCTGCCCAGC
  TCCCAGGACACCCCAAGCAAGAGAGGTGTCCGCACCCTGCACCAGCGCTTTCTGGCTCAG
  CTCAGGAAGTACTTCAACATGCGAGTGTTCCGCCAACGCACTTACCGCATCTGGGCCTTC
  GGAATTGCTGCTGCTGCCCTTGGCTACTTTGTTCCCTATGTACACCTGATGAAGTATGTG
  GAGGAGGAGTTCTCAGAAATCAAGGAGACCTGGGTGCTCTTGGTGTGTATTGGGGCTACC
  TCAGGCCTTGGGCGTCTTGTGTCAGGCCACATCAGTGACTCCATCCCTGGACTTAAGAAG
  ATCTACTTGCAGGTCCTTTCCTTCCTGCTCCTGGGCCTGATGTCCATGATGATTCCCCTG
  TGCCGGGACTTCGGGGGCCTTATCGTCGTCTGTCTTTTCCTGGGCCTTTGCGATGGCTTC
  TTCATCACCATCATGGCCCCCATTGCATTTGAGCTGGTGGGCCCAATGCAGGCCTCACAG
  GCCATTGGCTACCTCCTGGGCATGATGGCCCTGCCAATGATTGCTGGGCCCCCCATTGCA
  GGCCTACTCCGCAACTGTTTTGGGGACTACCATGTGGCCTTCTACTTTGCCGGTGTGCCC
  CCCATCATCGGGGCTGTAATCCTCTTCTTCGTCCCTCTGATGCATCAAAGGATGTTCAAG
  AAAGAGCAGAGAGATTCCAGCAAGGATAAGATGTTGGCCCCTGACCCAGACCCCAATGGG
  GAGCTACTGCCGGGCTCCCCCAACCCTGAGGAACCAATCTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_006517
• Insert Size: 4000 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006517.2, NP_006508.1
• RefSeq Size: 4401 bp
• RefSeq ORF: 1842 bp
• Locus ID: 6567
• Cytogenetics: Xq13.2
• Protein Families: Transmembrane
• Gene Summary: 'This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012]'