AIP1 (MAGI2) (NM_012301) Human Untagged Clone

CAT#: SC303954

MAGI2 (untagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 2 (MAGI2)


  "NM_012301" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol MAGI2
Synonyms ACVRIP1; AIP-1; AIP1; ARIP1; MAGI-2; NPHS15; SSCAM
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_012301 edited
ATGTCCAAAAGCTTGAAAAAGAAAAGCCACTGGACTAGCAAAGTCCATGAGAGTGTCATT
GGCAGGAACCCGGAGGGCCAGCTGGGCTTTGAACTGAAGGGGGGCGCCGAGAATGGACAG
TTCCCCTACCTGGGGGAGGTGAAGCCCGGCAAGGTGGCCTATGAGAGCGGCAGCAAATTG
GTGTCGGAGGAGCTGCTGCTGGAGGTGAACGAGACCCCCGTGGCGGGGCTCACCATCAGG
GACGTGCTGGCCGTGATCAAACACTGCAAGGACCCCCTCCGGCTCAAGTGTGTCAAGCAA
GGAGGAATTGTTGATAAAGACCTTCGTCACTACCTCAACTTACGATTTCAAAAGGGTTCT
GTGGACCATGAGCTTCAGCAAATCATTCGTGACAACCTCTACCTCCGCACGGTGCCATGC
ACCACAAGGCCACATAAGGAGGGTGAGGTCCCTGGAGTGGATTATATTTTCATCACTGTT
GAAGATTTTATGGAATTGGAGAAAAGTGGTGCTCTCCTAGAAAGTGGGACTTATGAAGAC
AATTACTACGGTACCCCAAAGCCGCCAGCAGAACCAGCACCATTATTGTTAAATGTAACA
GACCAGATACTTCCAGGAGCCACTCCAAGTGCTGAAGGAAAACGGAAGAGGAATAAATCA
GTGAGCAACATGGAGAAAGCCAGTATAGAGCCTCCTGAGGAGGAAGAGGAAGAGAGGCCT
GTGGTCAATGGAAATGGAGTAGTAGTAACACCAGAATCCAGTGAACATGAAGACAAAAGT
GCAGGTGCCTCAGGGGAGATGCCCTCCCAGCCTTATCCTGCACCAGTGTACAGTCAGCCT
GAGGAGCTGAAGGAGCAGATGGATGACACAAAGCCAACTAAACCTGAAGACAATGAGGAA
CCAGACCCATTGCCTGATAACTGGGAAATGGCCTATACAGAGAAGGGCGAAGTCTACTTC
ATTGACCATAACACAAAGACAACATCATGGCTGGATCCACGACTTGCGAAAAAAGCTAAA
CCTCCAGAAGAGTGCAAAGAAAATGAGCTTCCATATGGCTGGGAAAAAATCGATGATCCC
ATTTATGGCACTTATTATGTTGACCACATAAATAGAAGAACACAGTTTGAAAATCCTGTC
CTGGAAGCAAAAAGGAAGCTACAGCAACATAACATGCCCCACACAGAACTTGGAACAAAG
CCCCTGCAGGCCCCAGGTTTCCGAGAAAAACCACTCTTCACCCGGGATGCATCCCAGTTG
AAGGGAACATTCCTCAGCACCACCCTAAAAAAGAGCAACATGGGCTTTGGATTTACCATC
ATTGGTGGAGACGAGCCTGATGAGTTTCTGCAGGTGAAAAGTGTGATTCCGGATGGGCCT
GCAGCACAGGATGGAAAAATGGAAACAGGTGATGTCATTGTCTATATTAATGAAGTTTGT
GTCCTTGGACACACTCATGCAGATGTTGTCAAACTTTTCCAGTCTGTTCCTATTGGTCAG
AGTGTCAACCTGGTGTTGTGTCGTGGCTACCCTTTGCCCTTTGATCCTGAAGACCCTGCT
AACAGCATGGTGCCACCCCTTGCAATAATGGAGAGGCCACCTCCAGTGATGGTCAATGGA
AGACACAACTATGAAACATATTTGGAGTACATTTCTCGGACCTCACAGTCAGTTCCAGAT
ATAACAGATCGGCCGCCTCATTCTCTGCACTCCATGCCAACTGATGGTCAGCTAGACGGC
ACGTATCCACCGCCCGTCCATGATGACAATGTGTCTATGGCTTCATCTGGGGCCACCCAA
GCTGAACTTATGACCTTAACCATTGTGAAAGGTGCCCAGGGCTTCGGCTTCACTATTGCC
GACAGTCCTACAGGACAGCGGGTGAAACAAATACTTGACATTCAGGGATGCCCTGGCCTG
TGTGAAGGCGACCTCATTGTTGAGATCAACCAGCAGAATGTACAGAACCTGAGCCATACA
GAAGTAGTGGATATACTTAAGGACTGTCCCATTGGAAGTGAAACTTCTTTGATTATCCAT
CGAGGAGGTTTCTTTTCTCCATGGAAAACTCCAAAGCCTATAATGGACCGATGGGAGAAT
CAAGGCAGTCCTCAAACGAGTTTATCTGCTCCGGCCATACCGCAGAACCTGCCCTTCCCA
CCTGCCCTTCACAGGAGCTCCTTTCCTGACTCAACAGAGGCCTTTGACCCACGGAAGCCT
GATCCATATGAGCTCTACGAGAAATCTAGGGCCATTTATGAAAGTAGGCAACAAGTGCCA
CCCAGGACCAGTTTTCGAATGGATTCCTCTGGTCCAGATTATAAGGAATTGGATGTTCAT
CTTCGGAGGATGGAGTCTGGATTTGGCTTCAGAATCCTCGGGGGAGATGAGCCTGGACAG
CCTATTTTGATTGGAGCTGTCATTGCCATGGGCTCAGCCGACAGAGATGGCCGCCTTCAC
CCAGGAGATGAGCTTGTGTATGTTGATGGGATTCCAGTAGCCGGCAAAACCCACCGCTAT
GTCATCGACCTCATGCACCACGCAGCCCGCAATGGGCAGGTCAACCTCACTGTGAGAAGA
AAGGTGCTATGTGGAGGGGAGCCCTGCCCAGAGAACGGGAGAAGTCCAGGCTCTGTATCC
ACCCACCACAGCTCTCCACGCAGTGACTACGCAACCTACACCAACAGCAACCACGCTGCC
CCCAGTAGCAATGCCTCTCCCCCTGAAGGCTTCGCCTCCCACAGCCTGCAGACCAGTGAT
GTGGTCATTCACCGCAAAGAGAATGAGGGCTTCGGCTTTGTCATCATCAGCTCCCTGAAC
AGGCCTGAGTCTGGATCCACTATAACTGTGCCCCATAAAATCGGACGCATCATTGATGGG
AGTCCTGCAGATCGCTGTGCAAAACTAAAAGTGGGAGACCGGATCCTAGCAGTGAATGGC
CAGTCTATCATCAACATGCCTCACGCTGACATCGTGAAGCTCATCAAGGATGCAGGTCTT
AGTGTCACCCTTCGCATCATTCCTCAGGAGGAGCTCAACAGCCCCACCTCGGCACCCAGC
TCAGAGAAGCAGAGTCCCATGGCGCAGCAGAGTCCCCTGGCACAGCAGAGTCCCCTGGCC
CAGCCAAGCCCAGCCACCCCCAACAGCCCCATCGCCCAGCCAGCACCACCTCAACCACTT
CAGCTGCAAGGACACGAAAATAGTTACAGGTCAGAAGTGAAAGCAAGGCAAGATGTGAAA
CCAGACATCCGACAGCCTCCATTCACAGACTACAGGCAGCCCCCGCTGGATTACAGGCAA
CCCCCAGGAGGGGACTACCAGCAGCCCCCACCCTTGGACTACAGGCAGCCTCCCCTGCTG
GACTACAGGCAGCACTCCCCCGACACCAGGCAGTACCCTCTGTCGGACTACAGACAACCC
CAGGATTTTGATTATTTCACTGTGGACATGGAGAAAGGAGCCAAAGGATTTGGATTCAGC
ATTCGTGGAGGAAGGGAATACAAAATGGATTTGTATGTGTTGAGACTGGCAGAAGATGGA
CCAGCAATAAGGAATGGGAGGATGAGGGTAGGAGATCAAATCATTGAAATCAATGGGGAA
AGCACAAGGGACATGACACATGCCAGAGCAATAGAACTCATCAAATCTGGAGGAAGACGA
GTGAGGCTGCTGCTCAAGAGAGGCACGGGACAGGTCCCAGAATATGACGAACCCGCCCCC
TGGAGTTCTCCCGCTGCCGCCGCCCCAGGTCTGCCGGAAGTAGGCGTCTCCCTGGACGAC
GGCCTCGCTCCATTCTCTCCATCACATCCAGCCCCACCCTCCGACCCTTCCCACCAGATA
AGCCCAGGCCCAACTTGGGATATCAAACGGGAACACGACGTTAGGAAACCAAAGGAGCTT
TCAGCCTGCGGCCAGAAGAAGCAGCGCCTCGGGGAGCAGAGGGAGCGCTCGGCGAGTCCG
CAGAGGGCCGCGCGGCCGAGGCTCGAGGAGGCGCCCGGCGGCCAGGGGCGGCCCGAGGCC
GGCAGGCCCGCCTCGGAGGCCAGGGCGCCCGGGCTCGCGGCGGCAGACGCGGCGGACGCG
GTGCGGGCGGGCGGGAAGGAGGCGCCCCGTGCGGCGGCGGGCTCCGAGCTCTGCCGGCGC
GAAGGCCCGGGGGCTGTGCCGGCGTTTGCCGGCCCGGGCGGCGGCGGCAGCGGCGCGCTG
GAGGCCGAGGGCAGGGCGGGTGCGCGCGCGGGTCCCCGGCCGGGCCCGCGACCCCCGGGG
GGCGCCCCGGCGCGCAAGGCCGCCGTCGCGCCGGGGCCCTGGAAGGTGCCGGGTTCTGAC
AAGCTGCCCAGCGTCCTCAAACCCGGCGCCTCGGCCGCCAGCAGATGA
Restriction Sites Please inquire     
ACCN NM_012301
ORF Size 4368 bp
Insert Size 4400
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_012301.3, NP_036433.2
RefSeq Size 6880
RefSeq ORF 4368
Locus ID 9863
Protein Families Druggable Genome
Protein Pathways Tight junction
Gene Summary The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

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