AIP1 (MAGI2) (NM_012301) Human Untagged Clone

CAT#: SC303954

MAGI2 (untagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 2 (MAGI2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAGI2
• Synonyms: ACVRIP1; AIP-1; AIP1; ARIP1; MAGI-2; NPHS15; SSCAM
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012301 edited
  ATGTCCAAAAGCTTGAAAAAGAAAAGCCACTGGACTAGCAAAGTCCATGAGAGTGTCATT
  GGCAGGAACCCGGAGGGCCAGCTGGGCTTTGAACTGAAGGGGGGCGCCGAGAATGGACAG
  TTCCCCTACCTGGGGGAGGTGAAGCCCGGCAAGGTGGCCTATGAGAGCGGCAGCAAATTG
  GTGTCGGAGGAGCTGCTGCTGGAGGTGAACGAGACCCCCGTGGCGGGGCTCACCATCAGG
  GACGTGCTGGCCGTGATCAAACACTGCAAGGACCCCCTCCGGCTCAAGTGTGTCAAGCAA
  GGAGGAATTGTTGATAAAGACCTTCGTCACTACCTCAACTTACGATTTCAAAAGGGTTCT
  GTGGACCATGAGCTTCAGCAAATCATTCGTGACAACCTCTACCTCCGCACGGTGCCATGC
  ACCACAAGGCCACATAAGGAGGGTGAGGTCCCTGGAGTGGATTATATTTTCATCACTGTT
  GAAGATTTTATGGAATTGGAGAAAAGTGGTGCTCTCCTAGAAAGTGGGACTTATGAAGAC
  AATTACTACGGTACCCCAAAGCCGCCAGCAGAACCAGCACCATTATTGTTAAATGTAACA
  GACCAGATACTTCCAGGAGCCACTCCAAGTGCTGAAGGAAAACGGAAGAGGAATAAATCA
  GTGAGCAACATGGAGAAAGCCAGTATAGAGCCTCCTGAGGAGGAAGAGGAAGAGAGGCCT
  GTGGTCAATGGAAATGGAGTAGTAGTAACACCAGAATCCAGTGAACATGAAGACAAAAGT
  GCAGGTGCCTCAGGGGAGATGCCCTCCCAGCCTTATCCTGCACCAGTGTACAGTCAGCCT
  GAGGAGCTGAAGGAGCAGATGGATGACACAAAGCCAACTAAACCTGAAGACAATGAGGAA
  CCAGACCCATTGCCTGATAACTGGGAAATGGCCTATACAGAGAAGGGCGAAGTCTACTTC
  ATTGACCATAACACAAAGACAACATCATGGCTGGATCCACGACTTGCGAAAAAAGCTAAA
  CCTCCAGAAGAGTGCAAAGAAAATGAGCTTCCATATGGCTGGGAAAAAATCGATGATCCC
  ATTTATGGCACTTATTATGTTGACCACATAAATAGAAGAACACAGTTTGAAAATCCTGTC
  CTGGAAGCAAAAAGGAAGCTACAGCAACATAACATGCCCCACACAGAACTTGGAACAAAG
  CCCCTGCAGGCCCCAGGTTTCCGAGAAAAACCACTCTTCACCCGGGATGCATCCCAGTTG
  AAGGGAACATTCCTCAGCACCACCCTAAAAAAGAGCAACATGGGCTTTGGATTTACCATC
  ATTGGTGGAGACGAGCCTGATGAGTTTCTGCAGGTGAAAAGTGTGATTCCGGATGGGCCT
  GCAGCACAGGATGGAAAAATGGAAACAGGTGATGTCATTGTCTATATTAATGAAGTTTGT
  GTCCTTGGACACACTCATGCAGATGTTGTCAAACTTTTCCAGTCTGTTCCTATTGGTCAG
  AGTGTCAACCTGGTGTTGTGTCGTGGCTACCCTTTGCCCTTTGATCCTGAAGACCCTGCT
  AACAGCATGGTGCCACCCCTTGCAATAATGGAGAGGCCACCTCCAGTGATGGTCAATGGA
  AGACACAACTATGAAACATATTTGGAGTACATTTCTCGGACCTCACAGTCAGTTCCAGAT
  ATAACAGATCGGCCGCCTCATTCTCTGCACTCCATGCCAACTGATGGTCAGCTAGACGGC
  ACGTATCCACCGCCCGTCCATGATGACAATGTGTCTATGGCTTCATCTGGGGCCACCCAA
  GCTGAACTTATGACCTTAACCATTGTGAAAGGTGCCCAGGGCTTCGGCTTCACTATTGCC
  GACAGTCCTACAGGACAGCGGGTGAAACAAATACTTGACATTCAGGGATGCCCTGGCCTG
  TGTGAAGGCGACCTCATTGTTGAGATCAACCAGCAGAATGTACAGAACCTGAGCCATACA
  GAAGTAGTGGATATACTTAAGGACTGTCCCATTGGAAGTGAAACTTCTTTGATTATCCAT
  CGAGGAGGTTTCTTTTCTCCATGGAAAACTCCAAAGCCTATAATGGACCGATGGGAGAAT
  CAAGGCAGTCCTCAAACGAGTTTATCTGCTCCGGCCATACCGCAGAACCTGCCCTTCCCA
  CCTGCCCTTCACAGGAGCTCCTTTCCTGACTCAACAGAGGCCTTTGACCCACGGAAGCCT
  GATCCATATGAGCTCTACGAGAAATCTAGGGCCATTTATGAAAGTAGGCAACAAGTGCCA
  CCCAGGACCAGTTTTCGAATGGATTCCTCTGGTCCAGATTATAAGGAATTGGATGTTCAT
  CTTCGGAGGATGGAGTCTGGATTTGGCTTCAGAATCCTCGGGGGAGATGAGCCTGGACAG
  CCTATTTTGATTGGAGCTGTCATTGCCATGGGCTCAGCCGACAGAGATGGCCGCCTTCAC
  CCAGGAGATGAGCTTGTGTATGTTGATGGGATTCCAGTAGCCGGCAAAACCCACCGCTAT
  GTCATCGACCTCATGCACCACGCAGCCCGCAATGGGCAGGTCAACCTCACTGTGAGAAGA
  AAGGTGCTATGTGGAGGGGAGCCCTGCCCAGAGAACGGGAGAAGTCCAGGCTCTGTATCC
  ACCCACCACAGCTCTCCACGCAGTGACTACGCAACCTACACCAACAGCAACCACGCTGCC
  CCCAGTAGCAATGCCTCTCCCCCTGAAGGCTTCGCCTCCCACAGCCTGCAGACCAGTGAT
  GTGGTCATTCACCGCAAAGAGAATGAGGGCTTCGGCTTTGTCATCATCAGCTCCCTGAAC
  AGGCCTGAGTCTGGATCCACTATAACTGTGCCCCATAAAATCGGACGCATCATTGATGGG
  AGTCCTGCAGATCGCTGTGCAAAACTAAAAGTGGGAGACCGGATCCTAGCAGTGAATGGC
  CAGTCTATCATCAACATGCCTCACGCTGACATCGTGAAGCTCATCAAGGATGCAGGTCTT
  AGTGTCACCCTTCGCATCATTCCTCAGGAGGAGCTCAACAGCCCCACCTCGGCACCCAGC
  TCAGAGAAGCAGAGTCCCATGGCGCAGCAGAGTCCCCTGGCACAGCAGAGTCCCCTGGCC
  CAGCCAAGCCCAGCCACCCCCAACAGCCCCATCGCCCAGCCAGCACCACCTCAACCACTT
  CAGCTGCAAGGACACGAAAATAGTTACAGGTCAGAAGTGAAAGCAAGGCAAGATGTGAAA
  CCAGACATCCGACAGCCTCCATTCACAGACTACAGGCAGCCCCCGCTGGATTACAGGCAA
  CCCCCAGGAGGGGACTACCAGCAGCCCCCACCCTTGGACTACAGGCAGCCTCCCCTGCTG
  GACTACAGGCAGCACTCCCCCGACACCAGGCAGTACCCTCTGTCGGACTACAGACAACCC
  CAGGATTTTGATTATTTCACTGTGGACATGGAGAAAGGAGCCAAAGGATTTGGATTCAGC
  ATTCGTGGAGGAAGGGAATACAAAATGGATTTGTATGTGTTGAGACTGGCAGAAGATGGA
  CCAGCAATAAGGAATGGGAGGATGAGGGTAGGAGATCAAATCATTGAAATCAATGGGGAA
  AGCACAAGGGACATGACACATGCCAGAGCAATAGAACTCATCAAATCTGGAGGAAGACGA
  GTGAGGCTGCTGCTCAAGAGAGGCACGGGACAGGTCCCAGAATATGACGAACCCGCCCCC
  TGGAGTTCTCCCGCTGCCGCCGCCCCAGGTCTGCCGGAAGTAGGCGTCTCCCTGGACGAC
  GGCCTCGCTCCATTCTCTCCATCACATCCAGCCCCACCCTCCGACCCTTCCCACCAGATA
  AGCCCAGGCCCAACTTGGGATATCAAACGGGAACACGACGTTAGGAAACCAAAGGAGCTT
  TCAGCCTGCGGCCAGAAGAAGCAGCGCCTCGGGGAGCAGAGGGAGCGCTCGGCGAGTCCG
  CAGAGGGCCGCGCGGCCGAGGCTCGAGGAGGCGCCCGGCGGCCAGGGGCGGCCCGAGGCC
  GGCAGGCCCGCCTCGGAGGCCAGGGCGCCCGGGCTCGCGGCGGCAGACGCGGCGGACGCG
  GTGCGGGCGGGCGGGAAGGAGGCGCCCCGTGCGGCGGCGGGCTCCGAGCTCTGCCGGCGC
  GAAGGCCCGGGGGCTGTGCCGGCGTTTGCCGGCCCGGGCGGCGGCGGCAGCGGCGCGCTG
  GAGGCCGAGGGCAGGGCGGGTGCGCGCGCGGGTCCCCGGCCGGGCCCGCGACCCCCGGGG
  GGCGCCCCGGCGCGCAAGGCCGCCGTCGCGCCGGGGCCCTGGAAGGTGCCGGGTTCTGAC
  AAGCTGCCCAGCGTCCTCAAACCCGGCGCCTCGGCCGCCAGCAGATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_012301
• ORF Size: 4368 bp
• Insert Size: 4400
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012301.3, NP_036433.2
• RefSeq Size: 6880
• RefSeq ORF: 4368
• Locus ID: 9863
• Protein Families: Druggable Genome
• Protein Pathways: Tight junction
• Gene Summary: The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).