DUOX2 (NM_014080) Human Untagged Clone

CAT#: SC304038

DUOX2 (untagged)-Human dual oxidase 2 (DUOX2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DUOX2
• Synonyms: LNOX2; NOXEF2; P138-TOX; TDH6; THOX2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014080, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTCCGTGCAAGACCAGAGGCACTGATGCTCCTGGGAGCTCTTCTGACTGGATCCCTGGGTCCATCGG
  GCAATCAGGACGCACTCTCACTGCCCTGGGAAGTGCAGCGCTATGACGGCTGGTTTAACAACCTGAGGCA
  CCACGAGCGTGGTGCTGTTGGCTGCCGGTTGCAGCGCCGCGTACCAGCCAATTACGCCGACGGTGTGTAT
  CAGGCTCTGGAGGAGCCGCAGCTGCCCAACCCGCGCCGGCTCAGCAACGCAGCCACGCGGGGCATAGCCG
  GCCTGCCGTCGCTCCACAACCGCACCGTACTGGGGGTCTTCTTTGGCTACCATGTTCTTTCCGACGTGGT
  GAGCGTGGAAACGCCCGGTTGCCCCGCCGAGTTCCTCAACATCCGCATCCCACCTGGAGACCCCGTGTTC
  GACCCCGACCAGCGCGGGGACGTGGTGCTGCCCTTCCAGAGGAGCCGCTGGGACCCCGAGACCGGACGGA
  GTCCCAGCAACCCCCGGGACCTGGCCAACCAGGTGACGGGCTGGCTGGACGGCAGCGCCATCTATGGCTC
  CTCGCACTCCTGGAGCGACGCGCTGCGGAGCTTCTCGGGGGGACAGCTGGCGTCGGGGCCCGACCCCGCT
  TTCCCCCGAGACTCGCAGAACCCCCTGCTCATGTGGGCGGCGCCCGACCCCGCCACCGGGCAGAACGGGC
  CCCGGGGGCTGTACGCCTTCGGGGCAGAGAGAGGGAACCGGGAACCCTTCCTGCAGGCGCTGGGCCTGCT
  CTGGTTCCGCTACCACAACCTGTGGGCGCAGAGGCTGGCCCGCCAGCACCCAGACTGGGAGGACGAGGAG
  CTGTTCCAGCACGCACGCAAGAGGGTCATCGCCACCTACCAGAACATCGCTGTGTATGAGTGGCTGCCCA
  GCTTCCTGCAGAAAACACTCCCGGAGTATACAGGATACCGTCCTTTCCTAGACCCCAGCATCTCCCCGGA
  ATTTGTGGTGGCCTCTGAGCAGTTCTTCTCTACCATGGTGCCCCCTGGTGTCTACATGAGAAATGCCAGC
  TGTCATTTCCGGAAGGTCCTGAACAAGGGTTTTCAAAGCTCCCAAGCTCTCAGGGTCTGCAACAACTACT
  GGATTCGGGAGAACCCCAATCTGAACAGTACCCAGGAGGTGAATGAGCTGCTGCTGGGAATGGCCTCCCA
  GATTTCGGAGTTGGAGGACAACATAGTGGTTGAAGATCTGAGGGATTACTGGCCTGGCCCTGGCAAATTC
  TCCCGTACAGACTATGTGGCCAGCAGCATCCAACGTGGCCGAGATATGGGGCTGCCCAGCTATAGCCAGG
  CCCTGCTGGCCTTTGGGCTGGACATCCCAAGGAACTGGAGTGATCTCAACCCTAATGTGGACCCCCAGGT
  GCTGGAGGCCACAGCTGCCCTGTACAACCAGGACCTATCCCAGCTAGAGCTGCTCCTTGGGGGGCTCCTG
  GAGAGCCATGGGGACCCTGGACCCCTGTTCAGTGCCATTGTCCTCGACCAGTTTGTACGGCTGCGGGATG
  GTGACCGCTACTGGTTTGAGAACACCAGGAATGGGCTGTTCTCCAAGAAGGAGATTGAAGACATCCGAAA
  TACCACCCTGCGGGACGTGCTGGTCGCTGTTATCAACATTGACCCCAGTGCCCTGCAGCCCAATGTCTTT
  GTCTGGCATAAAGGTGCACCCTGCCCTCAACCTAAGCAGCTCACAACTGACGGCCTGCCCCAGTGTGCAC
  CCCTGACTGTGCTTGACTTCTTTGAAGGCAGCAGCCCTGGTTTTGCCATCACCATCATTGCTCTCTGCTG
  CCTTCCCTTAGTGAGTCTGCTTCTCTCTGGAGTGGTGGCCTATTTCCGGGGCCGAGAACACAAGAAGCTA
  CAAAAGAAACTCAAAGAGAGCGTGAAGAAGGAAGCAGCCAAAGATGGAGTGCCAGCGATGGAGTGGCCAG
  GCCCCAAGGAGAGGAGCAGTCCCATCATCATCCAGCTGCTGTCAGACAGGTGTCTGCAGGTCCTGAACAG
  GCATCTCACTGTGCTCCGTGTGGTCCAGCTGCAGCCTCTGCAGCAGGTCAACCTCATCCTGTCCAACAAC
  CGAGGATGCCGCACCCTGCTGCTCAAGATCCCTAAGGAGTATGACCTGGTGCTGCTGTTTAGTTCTGAAG
  AGGAACGGGGCGCCTTTGTGCAGCAGCTATGGGACTTCTGCGTGCGCTGGGCTCTGGGCCTCCATGTGGC
  TGAGATGAGCGAGAAGGAGCTATTTAGGAAGGCTGTGACAAAGCAGCAGCGGGAACGCATCCTGGAGATC
  TTCTTCAGACACCTTTTTGCTCAGGTGCTGGACATCAACCAGGCCGACGCAGGGACCCTGCCCCTGGACT
  CCTCCCAGAAGGTGCGGGAGGCCCTGACCTGCGAGCTGAGCAGGGCCGAGTTTGCCGAGTCCCTGGGCCT
  CAAGCCCCAGGACATGTTTGTGGAGTCCATGTTCTCTCTGGCTGACAAGGATGGCAATGGCTACCTGTCC
  TTCCGAGAGTTCCTGGACATCCTGGTGGTCTTCATGAAAGGCTCCCCAGAGGATAAGTCCCGTCTAATGT
  TTACCATGTATGACCTGGATGAGAATGGCTTCCTCTCCAAGGACGAATTCTTCACCATGATGCGATCCTT
  CATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCCGAGGTGGTGGAGTCTATGTTCCGGGAG
  TCGGGATTCCAGGACAAGGAGGAGCTGACATGGGAGGATTTTCACTTCATGCTGCGGGACCATGACAGCG
  AGCTCCGCTTCACGCAGCTCTGTGTCAAAGGTGGAGGTGGAGGTGGAAATGGTATTAGAGATATCTTTAA
  ACAAAACATCAGCTGTCGAGTCTCGTTCATCACTCGGACACCTGGGGAGCGCTCCCACCCCCAGGGACTG
  GGGCCCCCTGCCCCAGAAGCCCCAGAGCTGGGAGGCCCTGGACTGAAGAAGAGGTTTGGCAAAAAGGCAG
  CAGTGCCCACTCCCCGGCTGTACACAGAGGCGCTGCAAGAGAAGATGCAGCGAGGCTTCCTAGCCCAAAA
  GCTGCAGCAGTACAAGCGCTTCGTGGAGAACTACCGGAGGCACATCGTGTGTGTGGCAATCTTCTCGGCC
  ATCTGTGTTGGCGTGTTTGCAGATCGTGCTTACTACTATGGCTTTGCCTCGCCACCCTCGGACATTGCAC
  AGACCACCCTCGTGGGCATCATCCTGTCACGAGGCACGGCGGCCAGCGTCTCCTTCATGTTCTCTTATAT
  CTTGCTCACCATGTGCCGCAACCTCATAACCTTCCTGCGAGAGACTTTCCTCAACCGCTATGTGCCTTTT
  GATGCCGCAGTGGACTTCCACCGCTGGATCGCCATGGCTGCTGTTGTCCTGGCCATTTTGCACAGTGCTG
  GCCACGCAGTCAATGTCTACATCTTCTCAGTCAGCCCACTCAGCCTGCTGGCCTGCATATTCCCCAACGT
  CTTTGTGAATGATGGGTCCAAGCTTCCCCAGAAGTTCTATTGGTGGTTCTTCCAGACCGTCCCAGGTATG
  ACAGGTGTGCTTCTGCTCCTGGTCCTGGCCATCATGTATGTCTTCGCCTCCCACCACTTCCGCCGCCGCA
  GCTTCCGGGGCTTCTGGCTGACCCACCACCTCTACATCCTGCTCTATGCCCTGCTCATCATCCATGGCAG
  CTATGCTCTGATCCAGCTGCCCACTTTCCACATCTACTTCCTGGTCCCGGCAATCATCTATGGAGGTGAC
  AAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCGGAGCTGCTGCCCTCAGGAG
  TGACCTACCTGCAATTCCAGAGGCCCCAAGGCTTTGAGTACAAGTCAGGACAGTGGGTGCGGATCGCCTG
  CCTGGCTCTGGGGACCACCGAGTACCACCCCTTCACACTGACCTCCGCGCCCCATGAGGACACACTCAGC
  CTGCACATCCGGGCAGTGGGGCCCTGGACCACTCGCCTCAGGGAGATCTACTCATCCCCAAAGGGCAATG
  GCTGTGCTGGATACCCAAAGCTGTACCTTGATGGACCGTTTGGAGAGGGCCATCAGGAGTGGCATAAATT
  TGAGGTGTCAGTGTTGGTGGGAGGGGGCATTGGGGTCACCCCCTTTGCCTCCATCCTCAAAGACCTGGTC
  TTCAAGTCATCCTTGGGCAGCCAAATGCTGTGTAAGAAGATCTACTTCATCTGGGTGACACGGACCCAGC
  GTCAGTTTGAGTGGCTGGCTGACATCATCCAAGAGGTGGAGGAGAACGACCACCAGGACCTGGTGTCTGT
  GCACATTTATGTCACCCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTATACATCTGCGAGCGG
  CACTTCCAGAAAGTGCTGAACCGGAGTCTGTTCACGGGCCTGCGCTCCATCACCCACTTTGGCCGTCCCC
  CCTTCGAGCCCTTCTTCAACTCCCTGCAGGAGGTCCACCCACAGGTGCGCAAGATCGGGGTGTTCAGCTG
  CGGCCCTCCAGGAATGACCAAGAATGTAGAGAAGGCCTGTCAGCTCGTCAACAGGCAGGACCGAGCCCAC
  TTCATGCACCACTATGAGAACTTCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_014080
• ORF Size: 4647 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014080.3, NP_054799.3
• RefSeq Size: 6428
• RefSeq ORF: 4647
• Locus ID: 50506
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008]