FISH (SH3PXD2A) (NM_014631) Human Untagged Clone

CAT#: SC304145

SH3PXD2A (untagged)-Human SH3 and PX domains 2A (SH3PXD2A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SH3PXD2A
• Synonyms: FISH; SH3MD1; TKS5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014631, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTCGCCTACTGCGTGCAGGATGCCACCGTGGTGGACGTGGAGAAGCGGAGGAACCCCTCCAAGCACT
  ACGTATACATAATCAATGTGACCTGGTCTGACTCCACCTCCCAGACTATCTACCGGAGGTACAGCAAGTT
  CTTTGACCTGCAGATGCAGCTTTTGGATAAGTTTCCCATTGAAGGTGGCCAGAAGGACCCCAAGCAAAGG
  ATCATCCCCTTCCTCCCAGGCAAGATCCTCTTCCGCAGAAGCCACATCCGGGACGTAGCTGTGAAGAGAC
  TGAAGCCCATCGATGAATACTGCCGGGCACTTGTCCGGCTGCCCCCCCACATCTCACAGTGTGACGAAGT
  CTTCCGGTTCTTCGAGGCTCGACCCGAGGATGTCAACCCTCCAAAAGAGGACTATGGCAGTTCCAAGAGG
  AAATCAGTGTGGCTGTCCAGCTGGGCTGAGTCGCCCAAGAAGGACGTGACAGGTGCCGACGCCACCGCCG
  AGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCT
  CCAGGCCGGGGAGGTGGTGGATGTCATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAG
  GAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGAATGGTACTCGGGATGACTCCGACATCAACA
  CCTCTAAGACTGGAGAAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCAAGGACGAGAT
  TGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATAC
  CTGGGCAAAGAGGGCTGGGCGCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGA
  AGAACCTGGCCGGCCCAGTGGAGATCATTGGGAACATCATGGAGATCAGCAACCTGCTGAACAAGAAGGC
  GTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCCCCATTGCCAAGAAGGAGATC
  AGCCTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGC
  TGGCCCAGGGCTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACG
  GACAAGACCTCCACCACGCAGAGAATCCAGCCTGGGGTTCCAACTGCCAAAGCCACCAGAGCCCCCTTCT
  GTTGAGGTGGAGTACTACACCATTGCCGAATTCCAGTCGTGCATTTCCGATGGCATCAGCTTTCGGGGTG
  GACAGAAGGCAGAGGTCATTGATAAGAACTCAGGTGGCTGGTGGTACGTGCAGATCGGTGAGAAGGAGGG
  CTGGGCCCCCGCATCATACATCGATAAGCGCAAGAAGCCCAACCTGAGCCGCCGCACAAGCACGCTGACC
  CGGCCCAAGGTGCCCCCGCCAGCACCCCCCAGCAAGCCCAAGGAGGCCGAGGAGGGCCCTACGGGGGCCA
  GTGAGAGCCAGGACTCCCCGCGGAAGCTCAAGTATGAGGAGCCTGAGTATGACATCCCTGCATTCGGCTT
  TGACTCAGAGCCTGAGCTGAGCGAGGAGCCCGTGGAGGACAGAGCCTCAGGGGAGAGGCGGCCTGCCCAG
  CCCCACCGGCCCTCGCCGGCCTCTTCTCTGCAGCGGGCCCGCTTCAAGGTGGGTGAGTCTTCAGAGGATG
  TGGCCCTGGAAGAGGAGACCATCTATGAGAATGAGGGCTTCCGGCCATATGCAGAGGACACCCTGTCAGC
  CAGAGGCTCCTCCGGGGACAGCGACTCCCCAGGCAGCTCCTCGCTGTCCCTGACCAGGAAAAACTCCCCC
  AAATCAGGCTCCCCCAAGTCATCATCACTCCTAAAGCTCAAGGCAGAGAAGAATGCCCAGGCAGAAATGG
  GGAAGAACCACTCCTCAGCCTCCTTTTCCTCATCCATCACCATCAACACCACTTGCTGCTCCTCCTCTTC
  CTCCTCCTCCTCTTCCTTGTCCAAAACCAGTGGCGACCTGAAGCCCCGCTCTGCTTCGGACGCAGGCATC
  CGCGGCACTCCCAAGGTCAGGGCAAAGAAGGATGCTGATGCGAACGCTGGGCTGACCTCCTGTCCCCGGG
  CCAAGCCATCGGTCCGGCCCAAGCCATTCCTAAACCGAGCAGAGTCGCAGAGCCAAGAGAAGATGGACAT
  CAGCACTTTACGGCGCCAGCTGAGACCCACAGGCCAGCTCCGTGGAGGGCTCAAGGGCTCCAAGAGTGAG
  GATTCGGAGCTGCCCCCGCAGACGGCCTCCGAGGCTCCCAGTGAGGGGTCTAGGAGAAGCTCATCCGACC
  TCATCACCCTCCCAGCCACCACTCCCCCATGTCCCACCAAGAAGGAATGGGAAGGGCCAGCCACCTCGTA
  CATGACATGCAGCGCCTACCAGAAGGTCCAGGACTCGGAGATCAGCTTCCCCGCGGGCGTGGAGGTGCAG
  GTGCTGGAGAAGCAGGAGAGCGGGTGGTGGTATGTGAGGTTTGGGGAGCTGGAGGGCTGGGCCCCTTCCC
  ACTATTTGGTGCTGGATGAGAACGAGCAACCTGACCCCTCTGGCAAAGAGCTGGACACAGTGCCCGCCAA
  GGGCAGGCAGAACGAAGGCAAATCAGACAGCCTGGAGAAGATCGAGAGGCGCGTCCAAGCACTGAACACC
  GTCAACCAGAGCAAGAAGGCCACGCCCCCCATCCCCTCCAAACCTCCCGGGGGCTTCGGCAAGACCTCAG
  GCACTCCAGCGGTGAAGATGAGGAACGGAGTGCGGCAGGTGGCGGTCAGGCCCCAGTCGGTGTTTGTGTC
  CCCGCCACCCAAGGACAACAACCTGTCCTGCGCCCTGCGGAGGAATGAGTCACTCACGGCCACTGATGGC
  CTCCGAGGCGTCCGACGGAACTCCTCCTTTAGCACTGCTCGCTCCGCTGCCGCCGAGGCCAAGGGCCGCC
  TGGCCGAACGGGCTGCCAGCCAGGGTTCAGACTCACCCCTACTGCCCGCCCAGCGCAACAGCATACCCGT
  GTCCCCTGTGCGCCCCAAGCCCATCGAGAAGTCTCAGTTCATCCACAATAACCTCAAAGATGTGTACGTC
  TCTATCGCAGACTACGAGGGGGATGAGGAGACAGCAGGCTTCCAGGAGGGGGTGTCCATGGAGGTTCTGG
  AGAGGAACCCTAATGGCTGGTGGTACTGCCAGATCCTGGATGGTGTGAAGCCCTTCAAAGGCTGGGTGCC
  TTCCAACTACCTTGAGAAAAAGAACTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_014631
• ORF Size: 3318 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014631.2, NP_055446.2
• RefSeq Size: 11264
• RefSeq ORF: 3318
• Locus ID: 9644
• Gene Summary: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide. [UniProtKB/Swiss-Prot Function]