Acinus (ACIN1) (NM_014977) Human Untagged Clone

CAT#: SC304192

ACIN1 (untagged)-Human apoptotic chromatin condensation inducer 1 (ACIN1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACIN1
• Synonyms: ACINUS; ACN; fSAP152
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014977, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGAGACGGAAACATCCGAGGACATCCGGAGGAACCCGGGGAGTTCTGAGTGGTAATCGAGGGGTAG
  AGTATGGCAGTGGGCGGGGTCATCTCGGTACGTTCGAAGGGCGTTGGCGGAAATTACCGAAGATGCCCGA
  AGCCGTCGGGACGGACCCGAGTACCTCACGCAAGATGGCGGAGCTGGAGGAGGTGACTCTGGACGGGAAG
  CCTCTTCAGGCGCTGCGGGTGACCGACCTGAAGGCCGCACTGGAGCAGCGAGGCCTAGCCAAGAGCGGGC
  AGAAGAGTGCCCTGGTCAAGCGGCTCAAAGGGGCTCTAATGCTAGAAAATTTACAGAAACACTCAACACC
  CCATGCTGCATTCCAGCCAAATTCCCAGATTGGTGAGGAAATGAGCCAGAACAGTTTCATAAAACAGTAT
  CTGGAAAAGCAGCAGGAGCTACTTAGGCAGCGTCTGGAACGTGAAGCTCGAGAAGCTGCAGAACTTGAAG
  AAGCTTCAGCTGAGTCGGAGGACGAGATGATCCATCCTGAGGGAGTGGCTTCCCTGCTGCCTCCTGACTT
  TCAGAGCAGCCTGGAGAGACCAGAGCTGGAGCTCAGCAGACATTCGCCCAGAAAAAGCTCCTCAATTTCT
  GAAGAGAAAGGTGACTCTGATGATGAGAAACCAAGGAAAGGAGAAAGACGATCATCTAGGGTCAGACAGG
  CAAGAGCAGCTAAACTGTCTGAGGGCAGCCAACCTGCTGAGGAGGAAGAGGATCAAGAAACACCTTCCAG
  AAACCTAAGGGTCAGAGCAGATCGAAATTTGAAAACAGAGGAGGAAGAAGAGGAGGAGGAGGAGGAGGAA
  GAAGATGATGAAGAAGAGGAAGGTGATGATGAGGGACAAAAATCTAGGGAGGCACCAATCCTGAAAGAGT
  TTAAGGAAGAAGGGGAAGAGATACCTAGAGTAAAACCAGAGGAGATGATGGATGAGAGACCCAAAACAAG
  ATCCCAGGAACAGGAGGTGTTAGAGAGAGGAGGGAGATTTACAAGATCCCAGGAAGAGGCTAGAAAAAGT
  CATCTGGCCAGACAGCAGCAGGAGAAGGAAATGAAAACAACATCTCCCCTTGAGGAGGAAGAAAGAGAAA
  TAAAATCTTCACAAGGCTTAAAGGAAAAATCGAAGTCTCCTTCCCCTCCTCGACTGACTGAAGATCGAAA
  GAAGGCCTCACTTGTAGCGCTGCCAGAGCAAACTGCCAGCGAGGAGGAGACTCCTCCACCTTTACTAACA
  AAGGAAGCATCTTCTCCACCACCTCATCCACAGCTCCATAGCGAAGAAGAAATAGAGCCCATGGAAGGCC
  CAGCCCCCCCTGTCCTCATTCAGTTATCTCCTCCTAATACAGATGCTGACACCAGGGAGCTATTAGTATC
  TCAGCATACTGTCCAGTTGGTAGGAGGCCTGTCTCCTTTGTCAAGTCCTTCAGACACCAAAGCAGAATCT
  CCAGCAGAGAAAGTGCCAGAGGAGAGTGTCCTGCCTCTGGTTCAGAAAAGCACACTGGCTGACTACTCAG
  CCCAGAAGGATCTTGAACCTGAGTCAGACAGATCTGCTCAGCCCCTCCCTCTAAAAATTGAGGAATTAGC
  ACTGGCCAAAGGAATCACTGAAGAATGTCTGAAACAGCCATCTTTGGAACAGAAGGAAGGCAGAAGAGCT
  TCTCATACCCTTCTCCCAAGCCACAGATTGAAACAGTCAGCTGATTCATCCTCTAGCCGGTCCTCCTCAT
  CTTCCTCCTCCAGTTCTAGATCAAGATCTCGCTCTCCTGACAGTTCAGGTTCTCGGTCTCATTCACCGCT
  CAGATCCAAGCAGAGAGATGTAGCCCAGGCACGTACTCATGCCAACCCTCGTGGTAGACCCAAGATGGGC
  TCCAGATCAACATCAGAGTCCAGATCAAGGTCACGTTCACGTTCTCGTTCAGCATCAAGCAACAGCAGAA
  AATCTCTGAGCCCTGGAGTCTCCAGGGACAGCAGCACCAGCTATACTGAAACCAAAGATCCCTCTTCTGG
  TCAGGAGGTTGCAACTCCACCAGTGCCACAACTGCAGGTCTGTGAGCCAAAGGAGAGGACTTCCACCTCC
  TCATCCTCTGTCCAAGCAAGGCGTCTGAGTCAGCCTGAATCAGCTGAAAAGCATGTGACCCAGAGGTTAC
  AGCCTGAGCGGGGGAGCCCAAAGAAGTGTGAAGCTGAAGAGGCAGAGCCACCAGCTGCCACACAGCCCCA
  AACCTCAGAGACTCAGACCTCTCATCTGCCAGAATCAGAAAGAATTCATCACACTGTTGAGGAGAAGGAG
  GAAGTGACCATGGACACAAGTGAAAACAGACCTGAAAATGATGTTCCAGAACCTCCCATGCCTATTGCAG
  ACCAAGTCAGCAATGATGACCGCCCGGAGGGCAGTGTTGAAGATGAGGAGAAGAAAGAGAGCTCGCTGCC
  CAAATCATTCAAGAGGAAGATCTCCGTTGTCTCAGCTACCAAGGGGGTGCCAGCTGGAAACAGTGACACA
  GAGGGGGGCCAGCCTGGTCGGAAACGACGCTGGGGAGCCAGCACAGCCACCACACAGAAGAAACCTTCCA
  TCAGTATCACCACTGAATCACTAAAGAGCCTCATCCCCGACATCAAACCCCTGGCGGGGCAGGAGGCTGT
  TGTGGATCTTCATGCTGATGACTCTCGCATCTCTGAGGATGAGACAGAGCGTAATGGCGATGATGGGACC
  CATGACAAGGGGCTGAAAATATGCCGGACAGTCACTCAGGTAGTACCTGCAGAGGGCCAGGAGAATGGGC
  AGAGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTCCTGTACCTCCCCAGGTGTCAGTAGA
  GGTGGCCTTGCCCCCACCTGCAGAGCATGAAGTAAAGAAAGTGACTTTAGGAGATACCTTAACTCGACGT
  TCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCCT
  CCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGTCCGTCCTTTCACTTTAGGCCA
  GCTAAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCT
  CATTGCTTTGTAACGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCACGGGGTCAAAT
  GGCCCCAGTCCAATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGCTGGATTATCACCGAGG
  CCTCTTGGTGGACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCA
  CCCCCACCCCCGGTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGG
  AACAGTGGGCAGAACGGGAACGGGAAATGGAGCGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCG
  GGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGCCGCAAGGAACGTGCGAAG
  TCTAAAGAAAAGAAGAGTGAGAAGAAAGAGAAAGCCCAGGAGGAACCACCTGCCAAGCTGCTGGATGACC
  TTTTCCGAAAGACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGATCGTTCAGAA
  AGAGGCAGAGCGGGCCGAACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAA
  AAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACCGACAGCTGGAGCGAGAGAAACGTCGGGAGCACA
  GTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAGATCGGGATAGGGA
  AAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGG
  AGCACACCTGTGCGGGACCGGGGTGGGCGCCGCTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_014977
• ORF Size: 4026 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014977.3, NP_055792.1
• RefSeq Size: 4951
• RefSeq ORF: 4026
• Locus ID: 22985
• Protein Pathways: Spliceosome
• Gene Summary: Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1), also known as ACINUS-L.