Neurokinin 1 Receptor (TACR1) (NM_015727) Human Untagged Clone

CAT#: SC304352

TACR1 (untagged)-Human tachykinin receptor 1 (TACR1), transcript variant short

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TACR1
• Synonyms: NK1R; NKIR; SPR; TAC1R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015727 edited
  AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGAGAGGCCCGCGAAACTGCAGGCGGCGGCAGCGGCAGCAAAAGAGAA
  GGAAAAATCTCCAGCTGGATACGAAGCTCCAGAATCCTGGCCATAGGCTCAGAACTTTTA
  CAGGTCGCGCTGCAATGGGCCCCCACTCCCTCCTAAGTCCTCACGCAGCACAGGGCTTTG
  CCTTTCCCTGCGGAGGAAGGAGAAATAGGAGTTGCAGGCAGCAGCAGGTGCATAAATGCG
  GGGGATCTCTTGCTTCCTAGAACTGTGACCGGTGGAATTTCTTTCCCTTTTTCAGTTTAC
  CGCAAGAGAGATGCTGTCTCCAGACTTCTGAACTCAAACGTCTCCTGAAGCTTGAAAGTG
  GAGGAATTCAGAGCCACCGCGGGCAGGCGGGCAGTGCATCCAGAAGCGTTTATATTCTGA
  GCGCCAGTTCAGCTTTCAAAAAGAGTGCTGCCCAGAAAAAGCCTTCCACCCTCCTGTCTG
  GCTTTAGAAGGACCCTGAGCCCCAGGCGCCAGCCACAGGACTCTGCTGCAGAGGGGGGTT
  GTGTACAGATAGTAGGGCTTTACCGCCTAGCTTCGAAATGGATAACGTCCTCCCGGTGGA
  CTCAGACCTCTCCCCAAACATCTCCACTAACACCTCGGAACCCAATCAGTTCGTGCAACC
  AGCCTGGCAAATTGTCCTTTGGGCAGCTGCCTACACGGTCATTGTGGTGACCTCTGTGGT
  GGGCAACGTGGTAGTGATGTGGATCATCTTAGCCCACAAAAGAATGAGGACAGTGACGAA
  CTATTTTCTGGTGAACCTGGCCTTCGCGGAGGCCTCCATGGCTGCATTCAATACAGTGGT
  GAACTTCACCTATGCTGTCCACAACGAATGGTACTACGGCCTGTTCTACTGCAAGTTCCA
  CAACTTCTTTCCCATCGCCGCTGTCTTCGCCAGTATCTACTCCATGACGGCTGTGGCCTT
  TGATAGGTACATGGCCATCATACATCCCCTCCAGCCCCGGCTGTCAGCCACAGCCACCAA
  AGTGGTCATCTGTGTCATCTGGGTCCTGGCTCTCCTGCTGGCCTTCCCCCAGGGCTACTA
  CTCAACCACAGAGACCATGCCCAGCAGAGTCGTGTGCATGATCGAATGGCCAGAGCATCC
  GAACAAGATTTATGAGAAAGTGTACCACATCTGTGTGACTGTGCTGATCTACTTCCTCCC
  CCTGCTGGTGATTGGCTATGCATACACCGTAGTGGGAATCACACTATGGGCCAGTGAGAT
  CCCCGGGGACTCCTCTGACCGCTACCACGAGCAAGTCTCTGCCAAGCGCAAGGTGGTCAA
  AATGATGATTGTCGTGGTGTGCACCTTCGCCATCTGCTGGCTGCCCTTCCACATCTTCTT
  CCTCCTGCCCTACATCAACCCAGATCTCTACCTGAAGAAGTTTATCCAGCAGGTCTACCT
  GGCCATCATGTGGCTGGCCATGAGCTCCACCATGTACAACCCCATCATCTACTGCTGCCT
  CAATGACAGGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015727 unedited
  GCTGCCCAGNAAAAAGCCTTCCACCCTCCTGTCTGGCTTTAGAAGGACCCTGAGCCCCAG
  GCGCCAGCCACAGGACTCTGCTGCAGAGGGGGGTTGTGTACAGATAGTAGGGCTTTGCCG
  CCTAGCTTCGAAATGGATAACGTCCTCCCGGTGGACTCAGACCTCTCCCCAAACATCTCC
  ACTAACACCTCGGAACCCAATCAGTTCGTGCAACCAGCCTGGCAAATTGTCCTTTGGGCA
  GCTGCCTACACGGTCATTGTGGTGACCTCTGTGGTGGGCAACGTGGTAGTGATGTGGATC
  ATCTTAGCCCACAAAAGAATGAGGACAGTGACGAACTATTTTCTGGTGAACCTGGCCTTC
  GCGGAGGCCTCCATGGCTGCATTCAATACAGTGGTGAACTTCACCTATGCTGTCCACAAC
  GAATGGTACTACGGCCTGTTCTACTGCAAGTTCCACAACTTCTTTCCCATCGCCGCTGTC
  TTCGCCAGTATCTACTCCATGACGGCTGTGGCCTTTGATAGGTACATGGCCATCATACAT
  CCNCTCCAGCCCCGGCTGTCAGCCACAGCCACCAAAGTGGTCATCTGTGTCATCTGGGTC
  CTGGCTCTCCTGCTGGCCTTCCCNCCAGGCTACTACTCAACCACAGAGACCATGCCCAGC
  AGAGTCGTGTGCATGATCGAATGGCCAGAGCATCCGAACAAGATTTATGAGAAAGTGTAC
  CACATCTGTGTGACTGTGCTGATCTACTTCCTTCCCCTGCTGGTGATTGGCTATGCATAC
  ACGGTATTGGGAATCACACTATGGGCCAGTGAGATCCCGGGGGACTTCTCTGACCGGTAC
  CACAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015727 unedited
  NGGCCCCCTTGGAATGGCAACTTCCAGGNCCAGNAAAGCACTGGGGNAGGGTCACAGGNA
  TGCCACCCGGGNATTCTGTTCAGGNAAACAGCTATGACCGCGGCCGCAATCTCACCTGTC
  ATTGAGGCAGCAGTAGATGATGGGGTTGTACATGGTGGAGCTCATGGCCAGCCACATGAT
  GGCCAGGTAGACCTGCTGGATAAACTTCTTCAGGTAGAGATCTGGGTTGATGTAGGGCAG
  GAGGAAGAAGATGTGGAAGGGCAGCCAGCAGATGGCGAAGGTGCACACCACGACAATCAT
  CATTTTGACCACCTTGCGCTTGGCAGAGACTTGCTCGTGGTAGCGGTCAGAGGAGTCCCC
  GGGGATCTCACTGGCCCATAGTGTGATTCCCACTACGGTGTATGCATAGCCAATCACCAG
  CAGGGGGAGGAAGTAGATCAGCACAGTCACACAGATGTGGTACACTTTCTCATAAATCTT
  GTTCGGATGCTCTGGCCATTCGATCATGCACACGACTCTGCTGGGCATGGTCTCTGTGGT
  TGAGTAGTAGCCCTGNGGGAAGGCCAGCANGAGAGCCAGGACCCAGATGACACAGATGAC
  CACTTTGGTGGCTGTGGCTGACAGCCGGNGCTGGAGGGGATGTATGATGGCCATGTACCT
  ATCANAGGCACAGCCGTCATGGAGTAGATACTGGCGAAAGACAGCGCGATGGGGAAAGAA
  AGTGTGAAACTGCAGTAGAACAGGCCGTAGTACCATTNCGTGNNTGACAGCATAGTGAAG
  TTCACCACTGTATTGAATGCAGCCATGGAGGCCTNCGCGAAGGCCAGGTCACCANAAAAT
  AGTNCGTCACTGTCCTCATTCTTTTGGGGNCTAAGATGATCCCCATCACCTACACGTTNG
  CCACCACAGAA
  
• Restriction Sites: Please inquire
• ACCN: NM_015727
• Insert Size: 1600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_015727.1.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015727.1, NP_056542.1
• RefSeq Size: 1268 bp
• RefSeq ORF: 936 bp
• Locus ID: 6869
• Cytogenetics: 2p12
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: 'This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008]'
  Transcript Variant: This variant (short) uses a different splice site in the 3' coding region, compared to variant long. The resulting protein (isoform short) has a shorter and distinct C-terminus when compared to the long isoform. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.