EDD (UBR5) (NM_015902) Human Untagged Clone

CAT#: SC304366

UBR5 (untagged)-Human ubiquitin protein ligase E3 component n-recognin 5 (UBR5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBR5
• Synonyms: DD5; EDD; EDD1; HYD
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015902 edited
  ATGACGTCCATCCATTTCGTGGTTCACCCGCTGCCGGGCACCGAGGACCAGCTCAATGAC
  AGGTTACGAGAAGTTTCTGAGAAGCTGAACAAATATAATTTAAACAGCCACCCCCCTTTG
  AATGTATTGGAACAGGCTACTATTAAACAGTGTGTGGTGGGACCAAATCATGCTGCCTTT
  CTTCTTGAGGATGGTAGAGTTTGCAGGATTGGTTTTTCAGTACAGCCAGACAGATTGGAA
  TTGGGTAAACCTGATAATAATGATGGGTCAAAGTTGAACAGCAACTCGGGGGCAGGGAGG
  ACGTCAAGGCCTGGTAGGACAAGCGACTCTCCATGGTTTCTCTCAGGTTCTGAGACTCTA
  GGCAGGCTGGCAGGCAACACCTTAGGAAGCCGCTGGAGTTCTGGAGTGGGTGGAAGTGGT
  GGAGGATCCTCTGGTAGGTCATCAGCTGGAGCTCGAGATTCCCGCCGGCAGACTCGAGTT
  ATTCGGACAGGACGGGATCGAGGGTCTGGGCTTTTGGGCAGTCAGCCCCAGCCAGTTATT
  CCAGCATCTGTCATTCCAGAGGAGCTGATTTCACAGGCCCAAGTTGTTTTACAAGGCAAA
  TCCAGAAGTGTCATTATTCGAGAACTTCAGAGAACAAATCTTGATGTGAACCTTGCTGTA
  AATAATTTACTTAGCCGGGATGATGAAGATGGAGATGATGGGGATGATACAGCCAGCGAA
  TCTTATTTGCCTGGAGAGGATCTTATGTCTCTCCTTGATGCCGACATTCATTCTGCCCAC
  CCAAGTGTCATTATTGATGCAGATGCCATGTTTTCTGAAGACATTAGCTATTTTGGTTAC
  CCTTCTTTTCGTCGTTCATCACTTTCCAGGCTAGGCTCATCTCGAGTTCTCCTTCTTCCC
  TTAGAGAGAGACTCTGAGCTGTTGCGTGAACGTGAATCCGTTTTACGTTTACGTGAACGA
  AGGTGGCTTGATGGAGCCTCATTTGATAATGAAAGGGGTTCTACCAGCAAGGAAGGAGAG
  CCAAACTTGGATAAGAAGAATACACCTGTTCAAAGTCCAGTATCTCTAGGAGAAGATTTG
  CAGTGGTGGCCTGATAAGGATGGAACAAAATTCATCTGTATTGGGGCTCTGTATTCTGAA
  CTTCTGGCTGTCAGCAGTAAAGGAGAACTTTATCAGTGGAAATGGAGTGAATCTGAGCCT
  TACAGAAATGCCCAGAATCCTTCATTACATCATCCACGAGCAACATTTTTGGGGTTAACC
  AATGAAAAGATAGTCCTCCTGTCTGCAAATAGCATAAGAGCAACTGTAGCTACAGAAAAT
  AACAAGGTTGCTACATGGGTGGATGAAACTTTAAGTTCTGTGGCTTCTAAATTAGAGCAC
  ACTGCTCAGACTTACTCTGAACTTCAAGGAGAGCGGATAGTTTCTTTACATTGCTGTGCC
  CTTTACACCTGCGCTCAGCTGGAAAACAGTTTATATTGGTGGGGTGTAGTTCCTTTTAGT
  CAAAGGAAGAAAATGTTAGAGAAAGCTAGAGCAAAAAATAAAAAGCCTAAATCCAGTGCT
  GGTATTTCTTCAATGCCGAACATCACTGTTGGTACCCAGGTATGCTTGAGAAATAATCCT
  CTTTATCATGCTGGAGCAGTTGCATTTTCAATTAGTGCTGGGATTCCTAAAGTTGGTGTC
  TTAATGGAGTCAGTTTGGAATATGAATGACAGCTGTAGATTTCAACTTAGATCTCCTGAA
  AGCTTGAAAAACATGGAAAAAGCTAGCAAAACTACTGAAGCTAAGCCTGAAAGTAAGCAG
  GAGCCAGTGAAAACAGAAATGGGTCCTCCACCATCTCCAGCATCCACGTGTAGTGATGCA
  TCCTCAATTGCCAGCAGTGCATCAATGCCATACAAACGACGACGGTCAACCCCTGCACCA
  AAAGAAGAGGAAAAGGTGAATGAAGAGCAGTGGTCTCTTCGGGAAGTGGTTTTTGTGGAA
  GATGTCAAGAATGTTCCTGTTGGCAAGGTGCTAAAAGTAGATGGTGCCTATGTTGCTGTA
  AAATTTCCAGGAACCTCCAGTAATACTAACTGTCAGAACAGCTCTGGTCCAGATGCTGAC
  CCTTCTTCTCTCCTGCAGGATTGTAGGTTACTTAGAATTGATGAATTGCAGGTTGTCAAA
  ACTGGTGGAACACCGAAGGTTCCCGACTGTTTCCAAAGGACTCCTAAAAAGCTTTGTATA
  CCTGAAAAAACAGAAATATTAGCAGTGAATGTAGATTCCAAAGGTGTTCATGCTGTTCTG
  AAGACTGGAAATTGGGTACGATACTGTATCTTTGATCTTGCTACAGGAAAAGCAGAACAG
  GAAAATAATTTTCCTACAAGCAGCATTGCTTTCCTTGGTCAGAATGAGAGGAATGTAGCC
  ATTTTCACTGCTGGACAGGAATCTCCCATTATTCTTCGAGATGGAAATGGTACCATCTAC
  CCAATGGCCAAAGATTGCATGGGAGGAATAAGGGATCCCGATTGGCTGGATCTTCCACCT
  ATTAGTAGTCTTGGAATGGGTGTGCATTCTTTAATAAATCTTCCTGCCAATTCAACAATC
  AAAAAGAAAGCTGCTGTTATCATCATGGCTGTAGAGAAACAAACCTTAATGCAACACATT
  CTGCGCTGTGACTATGAGGCCTGTCGACAATATCTAATGAATCTTGAGCAAGCGGTTGTT
  TTAGAGCAGAATCTACAGATGCTGCAGACATTCATCAGCCACAGATGTGATGGAAATCGA
  AATATTTTGCATGCTTGTGTATCAGTTTGCTTTCCAACCAGCAATAAAGAAACTAAAGAA
  GAAGAGGAAGCGGAGCGTTCTGAAAGAAATACATTTGCAGAAAGGCTTTCTGCTGTTGAG
  GCCATTGCAAATGCAATATCAGTTGTTTCAAGTAATGGCCCAGGTAATCGGGCTGGATCA
  TCAAGTAGCCGAAGTTTGAGATTACGGGAAATGATGAGACGTTCGTTGAGAGCAGCTGGT
  TTGGGTAGACATGAAGCTGGAGCTTCATCCAGTGACCACCAGGATCCAGTTTCACCCCCC
  ATAGCTCCCCCTAGTTGGGTTCCTGACCCTCCTGCGATGGATCCTGATGGTGACATTGAT
  TTTATCCTGGCCCCCGCTGTGGGATCTCTTACCACAGCAGCAACCGGTACTGGTCAAGGA
  CCAAGCACCTCCACTATTCCAGGTCCTTCCACAGAGCCATCTGTAGTAGAATCCAAGGAT
  CGAAAGGCGAATGCTCATTTTATATTGAAATTGTTATGTGACAGTGTGGTTCTCCAGCCC
  TATCTACGAGAACTTCTTTCTGCCAAGGATGCAAGAGGGATGACCCCATTTATGTCAGCT
  GTAAGTGGCCGAGCTTATCCTGCTGCAATTACCATCTTAGAAACTGCTCAGAAAATTGCA
  AAAGCTGAAATATCCTCAAGTGAAAAAGAGGAAGATGTATTCATGGGAATGGTTTGCCCA
  TCAGGTACCAACCCTGATGACTCTCCTTTATATGTTTTATGTTGTAATGACACTTGCAGT
  TTTACATGGACTGGAGCAGAGCACATTAACCAGGATATTTTTGAGTGTCGAACTTGTGGC
  TTGCTGGAGTCACTGTGTTGTTGTACGGAATGTGCAAGGGTTTGTCATAAAGGTCATGAT
  TGCAAACTCAAACGGACATCACCAACAGCCTACTGTGATTGTTGGGAGAAATGTAAATGT
  AAAACTCTTATTGCTGGACAGAAATCTGCTCGTCTTGATCTACTTTATCGCCTGCTCACT
  GCTACTAATCTGGTTACTCTGCCAAACAGCAGGGGAGAGCACCTCTTACTATTCTTAGTA
  CAGACAGTCGCAAGGCAGACGGTGGAGCATTGTCAATACAGGCCACCTCGAATCAGGGAA
  GATCGTAACCGAAAAACAGCCAGTCCTGAAGATTCAGATATGCCAGATCATGATTTAGAG
  CCTCCAAGATTTGCCCAGCTTGCATTGGAGCGTGTTCTACAGGACTGGAATGCCTTGAAA
  TCTATGATTATGTTTGGGTCGCAGGAGAATAAAGACCCTCTTAGTGCCAGCAGTAGAATA
  GGCCATCTTTTGCCAGAAGAGCAAGTATACCTCAATCAGCAAAGTGGCACAATTCGGCTG
  GACTGTTTCACTCATTGCCTTATAGTTAAGTGTACAGCAGATATTTTGCTTTTAGATACT
  CTACTAGGTACACTAGTGAAAGAACTCCAAAACAAATATACACCTGGACGTAGAGAAGAA
  GCTATTGCTGTGACAATGAGGTTTCTACGTTCAGTGGCAAGAGTTTTTGTTATTCTGAGT
  GTGGAAATGGCTTCATCCAAAAAGAAAAACAACTTTATTCCACAGCCAATTGGAAAATGC
  AAGCGTGTATTCCAAGCATTGCTACCTTACGCTGTGGAAGAATTGTGCAACGTAGCAGAG
  TCACTGATTGTTCCTGTCAGAATGGGGATTGCTCGTCCAACTGCACCATTTACCCTGGCT
  AGTACTAGCATAGATGCCATGCAGGGCAGTGAAGAATTATTTTCAGTGGAACCACTACCA
  CCACGACCATCATCTGATCAGTCTAGCAGCTCCAGTCAGTCTCAGTCATCCTACATCATC
  AGGAATCCACAGCAGAGGCGCATCAGCCAGTCACAGCCCGTTCGGGGCAGAGATGAAGAA
  CAGGATGATATTGTTTCAGCAGATGTGGAAGAGGTTGAGGTGGTGGAGGGTGTGGCTGGA
  GAAGAGGATCATCATGATGAACAGGAAGAACACGGGGAAGAAAATGCTGAGGCAGAGGGA
  CAACATGATGAGCATGATGAAGACGGGAGTGATATGGAGCTGGACTTGTTAGCAGCAGCT
  GAAACAGAAAGTGATAGTGAAAGTAACCACAGCAACCAAGATAATGCTAGTGGGCGCAGA
  AGCGTTGTCACTGCAGCAACTGCTGGTTCAGAAGCAGGAGCAAGCAGTGTTCCTGCCTTC
  TTTTCTGAAGATGATTCTCAATCGAATGACTCAAGTGATTCTGATAGCAGTAGTAGTCAG
  AGTGACGACATAGAACAGGAGACCTTTATGCTTGATGAGCCATTAGAAAGAACCACAAAT
  AGCTCCCATGCCAATGGTGCTGCCCAAGCTCCCCGTTCAATGCAGTGGGCTGTCCGCAAC
  ACCCAGCATCAGCGAGCAGCCAGTACAGCCCCTTCCAGTACATCTACACCAGCAGCAAGT
  TCAGCGGGTTTGATTTATATTGATCCTTCAAACTTACGCCGGAGTGGTACCATCAGTACA
  AGTGCTGCAGCTGCAGCAGCTGCTTTGGAAGCTAGCAACGCCAGCAGTTACCTAACATCT
  GCAAGCAGTTTAGCCAGGGCTTACAGCATTGTCATTAGACAAATCTCGGACTTGATGGGC
  CTTATTCCTAAGTATAATCACCTAGTATACTCTCAGATTCCAGCAGCTGTGAAATTGACT
  TACCAAGATGCAGTAAACTTACAGAACTATGTAGAAGAAAAGCTTATTCCCACTTGGAAC
  TGGATGGTCAGTATTATGGATTCTACTGAAGCTCAATTACGTTATGGTTCTGCATTAGCA
  TCTGCTGGTGATCCTGGACATCCAAATCATCCTCTTCACGCTTCTCAGAATTCAGCGAGA
  AGAGAGAGGATGACTGCGCGAGAAGAAGCTAGCTTACGAACACTTGAAGGCAGACGACGT
  GCCACCTTGCTTAGCGCCCGTCAAGGAATGATGTCTGCACGAGGAGACTTCCTAAATTAT
  GCTCTGTCTCTAATGCGGTCTCATAATGATGAGCATTCTGATGTTCTTCCAGTTTTGGAT
  GTTTGCTCATTGAAGCATGTGGCATATGTTTTTCAAGCACTTATATACTGGATTAAGGCA
  ATGAATCAGCAGACAACATTGGATACACCTCAACTAGAACGCAAAAGGACGCGAGAACTC
  TTGGAACTGGGTATTGATAATGAAGATTCAGAACATGAAAATGATGATGACACCAATCAA
  AGTGCTACTTTGAATGATAAGGATGATGACTCTCTTCCTGCAGAAACTGGCCAAAACCAT
  CCATTTTTCCGACGTTCAGACTCCATGACATTCCTTGGGTGTATACCCCCAAATCCATTT
  GAAGTGCCTCTGGCTGAAGCCATCCCCTTGGCTGATCAGCCACATCTGTTGCAGCCAAAT
  GCTAGAAAGGAGGATCTTTTTGGCCGTCCAAGTCAGGGTCTTTATTCTTCATCTGCCAGT
  AGTGGGAAATGTTTAATGGAGGTTACAGTGGATAGAAACTGCCTAGAGGTTCTTCCAACA
  AAAATGTCTTATGCTGCCAATCTGAAAAATGTAATGAACATGCAAAACCGGCAAAAAAAA
  GAAGGGGAAGAACAGCCCGTGCTGCCAGAAGAAACTGAGAGTTCAAAACCAGGGCCATCT
  GCTCATGATCTTGCTGCACAATTAAAAAGTAGCTTACTAGCAGAAATAGGACTTACTGAA
  AGTGAAGGGCCACCTCTCACATCTTTCAGGCCACAGTGTAGCTTTATGGGAATGGTTATT
  TCCCATGATATGCTGCTAGGACGTTGGCGCCTTTCTTTAGAACTGTTCGGCAGGGTATTC
  ATGGAAGATGTTGGAGCAGAACCTGGATCAATCCTAACTGAATTGGGTGGTTTTGAGGTA
  AAAGAATCAAAATTCCGCAGAGAAATGGAAAAACTGAGAAACCAGCAGTCAAGAGATTTG
  TCACTAGAGGTTGATCGGGATCGAGATCTTCTCATTCAGCAGACTATGAGGCAGCTTAAC
  AATCACTTTGGTCGAAGATGTGCTACTACACCAATGGCTGTACACAGAGTAAAAGTCACA
  TTTAAGGATGAGCCAGGAGAGGGCAGTGGTGTAGCACGAAGTTTTTATACAGCCATTGCA
  CAAGCATTTTTATCAAATGAAAAATTGCCAAATCTAGAGTGTATCCAAAATGCCAACAAA
  GGCACCCACACAAGTTTAATGCAGAGATT:AAGGAACCGAGGAGAGAGAGACCGGGAAAG
  GGAGAGAGAAAGGGAAATGAGGAGGAGTAGTGGTTTGCGAGCAGGTTCTCGGAGGGACCG
  GGATAGAGACTTTAGAAGACAGCTTTCCATCGACACTAGGCCCTTTAGACCAGCCTCTGA
  AGGGAATCCTAGCGATGATCCTGAGCCTTTGCCAGCACATCGGCAGGCACTTGGAGAGAG
  GCTTTATCCTCGTGTACAAGCAATGCAACCAGCATTTGCAAGTAAAATCACTGGCATGTT
  GTTGGAATTATCCCCAGCTCAGCTGCTTCTCCTTCTAGCAAGTGAGGATTCTCTGAGAGC
  AAGAGTGGATGAGGCCATGGAACTCATTATTGCACATGGACGGGAAAATGGAGCTGATAG
  TATCCTGGATCTTGGATTAGTAGACTCCTCAGAAAAGGTACAGCAGGAAAACCGAAAGCG
  CCATGGCTCTAGTCGAAGTGTAGTAGATATGGATTTAGATGATACAGATGATGGTGATGA
  CAATGCCCCTTTGTTTTACCAACCTGGGAAAAGAGGATTTTATACTCCAAGGCCTGGCAA
  GAACACAGAAGCAAGGTTGAATTGTTTCAGAAACATTGGCAGGATTCTTGGACTATGTCT
  GTTACAGAATGAACTATGTCCTATCACATTGAATAGACATGTAATTAAAGTATTGCTTGG
  TAGAAAAGTCAATTGGCATGATTTTGCTTTTTTTGATCCTGTAATGTATGAGAGTTTGCG
  GCAACTAATCCTCGCGTCTCAGAGTTCAGATGCTGATGCTGTTTTCTCAGCAATGGATTT
  GGCATTTGCAATTGACCTGTGTAAAGAAGAAGGTGGAGGACAGGTTGAACTCATTCCTAA
  TGGTGTAAATATACCAGTCACTCCACAGAATGTATATGAGTATGTGCGGAAATACGCAGA
  ACACAGAATGTTGGTAGTTGCAGAACAGCCCTTACATGCAATGAGGAAAGGTCTACTAGA
  TGTGCTTCCAAAAAATTCATTAGAAGATTTAACGGCAGAAGATTTTAGGCTTTTGGTAAA
  TGGCTGCGGTGAAGTCAATGTGCAAATGCTGATCAGTTTTACCTCTTTCAATGATGAATC
  AGGAGAAAATGCTGAGAAGCTTCTGCAGTTCAAGCGTTGGTTCTGGTCAATAGTAGAGAA
  GATGAGCATGACAGAACGACAAGATCTTGTTTACTTTTGGACATCAAGCCCATCACTGCC
  AGCCAGTGAAGAAGGATTCCAGCCTATGCCCTCAATCACAATAAGACCACCAGATGACCA
  ACATCTTCCTACTGCAAATACTTGCATTTCTCGACTTTACGTCCCACTCTATTCCTCTAA
  ACAGATTCTCAAACAGAAATTGTTACTCGCCATTAAGACCAAGAATTTTGGTTTTGTGTA
  G
  
• Restriction Sites: Please inquire
• ACCN: NM_015902
• ORF Size: 8400 bp
• Insert Size: 8400
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015902.4, NP_056986.2
• RefSeq Size: 9410
• RefSeq ORF: 8400
• Locus ID: 51366
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.