Calpain 9 (CAPN9) (NM_016452) Human Untagged Clone

CAT#: SC304422

CAPN9 (untagged)-Human calpain 9 (CAPN9), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CAPN9
• Synonyms: GC36; nCL-4
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_016452, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCTTACCTCTACCGGGCCCCAGGGCCTCAGGCACACCCGGTTCCCAAGGACGCCCGGATCACCCACT
  CCTCAGGCCAGAGCTTTGAGCAAATGAGGCAGGAGTGCCTGCAGAGAGGCACCCTGTTTGAGGATGCAGA
  CTTCCCAGCCAGCAATTCCTCCCTGTTCTACAGTGAGAGGCCGCAGATCCCCTTTGTGTGGAAACGACCA
  GGGGAAATCGTGAAAAACCCAGAATTCATTCTTGGAGGGGCCACCAGGACTGATATCTGCCAGGGAGAGC
  TGGGAGACTGCTGGCTATTAGCCGCCATCGCCTCCCTTACGCTTAATCAAAAAGCACTGGCCAGAGTCAT
  CCCCCAGGACCAAAGCTTTGGCCCTGGTTATGCCGGGATATTCCATTTCCAGTTCTGGCAGCACAGTGAG
  TGGCTGGACGTGGTGATCGATGACCGCCTGCCCACCTTCAGGGACCGCTTGGTTTTCCTCCACTCTGCCG
  ACCACAACGAGTTCTGGAGCGCCTTGCTGGAAAAAGCCTACGCCAAGCTAAATGGGAGCTATGAAGCTCT
  GAAGGGAGGCAGCGCCATCGAGGCCATGGAAGACTTCACTGGGGGTGTGGCAGAGACCTTCCAAACTAAA
  GAGGCCCCCGAGAACTTCTATGAGATTCTAGAGAAGGCTTTGAAGAGAGGCTCCCTGCTGGGCTGCTTCA
  TTGATACCAGAAGTGCTGCAGAATCTGAGGCCCGGACGCCGTTTGGTCTTATTAAGGGTCATGCCTACAG
  TGTAACGGGAATTGACCAGGTAAGCTTCCGAGGCCAGAGAATCGAGCTCATCCGAATCCGGAACCCTTGG
  GGCCAGGTTGAGTGGAACGGGTCGTGGAGCGACAGGATGGCATTTAAGGACTTCAAGGCCCACTTTGATA
  AAGTGGAGATCTGCAACCTCACTCCCGATGCCCTGGAGGAAGACGCGATCCACAAATGGGAGGTGACGGT
  CCATCAGGGAAGCTGGGTTCGCGGCTCCACGGCTGGGGGCTGCCGCAATTTCCTGGATACCTTTTGGACC
  AATCCACAAATAAAATTGTCTCTGACTGAGAAAGATGAGGGGCAGGAGGAGTGTAGTTTCCTTGTAGCCC
  TGATGCAGAAAGATAGAAGGAAACTCAAGAGATTTGGTGCCAATGTGCTGACAATCGGCTATGCCATTTA
  TGAGTGCCCTGACAAAGACGAACACCTGAACAAAGACTTCTTCAGATACCACGCTTCTCGGGCCAGAAGC
  AAGACGTTCATCAACCTGAGAGAAGTCTCCGACCGGTTCAAGCTGCCCCCTGGGGAGTACATCCTGATTC
  CCAGCACTTTTGAGCCCCACCAGGAAGCTGATTTCTGTCTGAGAATCTTTTCAGAGAAAAAAGCCATTAC
  CCGGGATATGGATGGAAATGTAGACATTGACCTTCCTGAGCCTCCAAAGCCAACTCCACCTGACCAGGAG
  ACAGAGGAGGAGCAGCGGTTTCGGGCTCTGTTTGAACAAGTCGCTGGTGAGGACATGGAGGTGACAGCAG
  AGGAACTTGAGTATGTTTTAAATGCTGTGCTGCAAAAGAAAAAGGACATCAAATTCAAGAAGCTAAGCCT
  GATCTCCTGTAAAAACATCATTTCCCTGATGGACACCAGCGGCAATGGGAAGCTGGAGTTTGATGAATTC
  AAAGTGTTCTGGGACAAGCTGAAGCAGTGGATTAACCTTTTCCTTCGGTTTGATGCTGACAAGTCCGGCA
  CCATGTCTACCTATGAACTACGGACTGCACTGAAAGCTGCAGGCTTTCAGCTGAGCAGCCACCTCCTGCA
  GCTGATTGTGCTCAGGTATGCGGATGAGGAGCTCCAGCTGGACTTCGATGACTTCCTCAACTGCCTGGTC
  CGGCTGGAGAATGCGAGCCGGGTGTTCCAGGCTCTCAGTACAAAGAACAAGGAGTTCATTCATCTCAATA
  TAAATGAGTTCATCCATTTGACAATGAACATCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_016452
• ORF Size: 1995 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016452.2, NP_057536.1
• RefSeq Size: 2284
• RefSeq ORF: 1995
• Locus ID: 10753
• Protein Families: Druggable Genome, Protease
• Gene Summary: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.