SOX6 (NM_017508) Human Untagged Clone

CAT#: SC304470

SOX6 (untagged)-Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SOX6
• Synonyms: HSSOX6; SOXD
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017508, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAAGAATGTCTTCCAAGCAAGCCACCTCTCCATTTGCCTGTGCAGCTGATGGAGAGGATGCAATGA
  CCCAGGATTTAACCTCAAGGGAAAAGGAAGAGGGCAGTGATCAACATGTGGCCTCCCATCTGCCTCTGCA
  CCCCATAATGCACAACAAACCTCACTCTGAGGAGCTACCAACACTTGTCAGTACCATTCAACAAGATGCT
  GACTGGGACAGCGTTCTGTCATCTCAGCAAAGAATGGAATCAGAGAATAATAAGTTATGTTCCCTATATT
  CCTTCCGAAATACCTCTACCTCACCACATAAGCCTGACGAAGGGAGTCGGGACCGTGAGATAATGACCAG
  TGTTACTTTTGGAACCCCAGAGCGCCGCAAAGGGAGTCTTGCCGATGTGGTGGACACACTGAAACAGAAG
  AAGCTTGAGGAAATGACTCGGACTGAACAAGAGGATTCCTCCTGCATGGAAAAACTACTTTCAAAAGATT
  GGAAGGAAAAAATGGAAAGACTAAATACCAGTGAACTTCTTGGAGAAATTAAAGGTACACCTGAGAGCCT
  GGCAGAAAAAGAACGGCAGCTCTCCACCATGATTACCCAGCTGATCAGTTTACGGGAGCAGCTACTGGCA
  GCGCATGATGAACAGAAAAAACTGGCAGCGTCACAAATTGAGAAACAACGGCAGCAAATGGACCTTGCTC
  GCCAACAGCAAGAACAGATTGCGAGACAACAGCAGCAACTTCTGCAACAGCAGCACAAAATTAATCTCCT
  GCAGCAACAGATCCAGGTTCAGGGTCACATGCCTCCGCTCATGATCCCAATTTTTCCACATGACCAGCGG
  ACTCTGGCAGCAGCTGCTGCTGCCCAACAGGGATTCCTCTTCCCCCCTGGAATAACATACAAACCAGGTG
  ATAACTACCCCGTACAGTTCATTCCATCAACAATGGCAGCTGCTGCTGCTTCTGGACTCAGCCCTTTACA
  GCTCCAGCAGCTCTATGCCGCTCAGCTGGCCAGCATGCAGGTGTCACCTGGAGCAAAGATGCCATCAACT
  CCACAGCCACCAAACACAGCAGGGACGGTCTCACCTACTGGGATAAAAAATGAAAAGAGAGGGACCAGCC
  CTGTAACTCAAGTTAAGGATGAAGCAGCAGCACAGCCTCTGAATCTCTCATCCCGACCCAAGACAGCAGA
  GCCTGTAAAGTCCCCAACGTCTCCCACCCAGAACCTCTTCCCAGCCAGCAAAACCAGCCCTGTCAATCTG
  CCAAACAAAAGCAGCATCCCTAGCCCCATTGGAGGAAGCCTGGGAAGAGGATCCTCTTTAGGTAAATGGA
  AAAGTCAACACCAGGAAGAGACTTACGAATTAGATATCCTATCTAGTCTCAACTCCCCTGCCCTTTTTGG
  GGATCAGGATACAGTGATGAAAGCCATTCAGGAGGCGCGGAAGATGCGAGAGCAGATCCAGCGGGAGCAA
  CAGCAGCAACAGCCACATGGTGTTGACGGGAAACTGTCCTCCATAAATAATATGGGGCTGAACAGCTGCA
  GGAATGAAAAGGAAAGAACGCGCTTTGAGAATTTGGGGCCCCAGTTAACGGGAAAGTCAAATGAAGATGG
  AAAACTGGGCCCAGGTGTCATCGACCTTACTCGGCCAGAAGATGCAGAGGGAAGTAAAGCAATGAATGGC
  TCTGCAGCTAAACTACAGCAGTATTATTGTTGGCCAACAGGAGGTGCCACTGTGGCTGAAGCACGAGTCT
  ACAGGGACGCCCGCGGCCGTGCCAGCAGCGAGCCACACATTAAGCGACCAATGAATGCATTCATGGTTTG
  GGCAAAGGATGAGAGGAGAAAAATCCTTCAGGCCTTCCCCGACATGCATAACTCCAACATTAGCAAAATC
  TTAGGATCTCGCTGGAAATCAATGTCCAACCAGGAGAAGCAACCTTATTATGAAGAGCAGGCCCGGCTAA
  GCAAGATCCACTTAGAGAAGTACCCAAACTATAAATACAAACCCCGACCGAAACGCACCTGCATTGTTGA
  TGGCAAAAAGCTTCGGATTGGGGAGTATAAGCAACTGATGAGGTCTCGGAGACAGGAGATGAGGCAGTTC
  TTTACTGTGGGGCAACAGCCTCAGATTCCAATCACCACAGGAACAGGTGTTGTGTATCCTGGTGCTATCA
  CTATGGCAACTACCACACCATCGCCTCAGATGACATCTGACTGCTCTAGCACCTCGGCCAGCCCGGAGCC
  CAGCCTCCCGGTCATCCAGAGCACTTATGGTATGAAGACAGATGGCGGAAGCCTAGCTGGAAATGAAATG
  ATCAATGGAGAGGATGAAATGGAAATGTATGATGACTATGAAGATGACCCCAAATCAGACTATAGCAGTG
  AAAATGAAGCCCCGGAGGCTGTCAGTGCCAACTGA
  
  
• Restriction Sites: Please inquire
• ACCN: NM_017508
• ORF Size: 2415 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017508.1, NP_059978.1
• RefSeq Size: 5158
• RefSeq ORF: 2415
• Locus ID: 55553
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (1) encodes isoform b. Variants 1 and 3 both encode the same isoform (b). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. CCDS Note: The coding region has been updated to start at a downstream in-frame start codon that is supported by conservation data.