ABCD4 (NM_020325) Human Untagged Clone

CAT#: SC304737

ABCD4 (untagged)-Human ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCD4
• Synonyms: ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF Sequence for NM_020325. The custom clone sequence may differ by one or more nucleotides
  ATGGCGGTCGCGGGGCCCGCGCCCGGAGCTGGCGCCAGGCCCAGGTTAGATCTGCAATTT
  CTCCAGCGGTTCCTGCAGATACTGAAGGTTTTGTTTCCTTCTTGGTCATCACAAAATGCC
  TTGATGTTCCTGACCCTTTTGTGCCTGACCCTACTGGAGCAATTTGTGATCTACCAGGTT
  GGCTTGATCCCCAGTCAGTACTATGGGGTCCTGGGAAACAAAGACTTGGAAGGGTTTAAG
  ACTCTGACATTCCTGGCTGTCATGCTCATTGTTCTGAACTCCACGCTGAAGAGCTTTGAT
  CAGTTCACCTGCAACCTGCTGTATGTGAGCTGGAGGAAGGACCTCACTGAGCACCTTCAC
  CGCCTCTACTTCCGGGGCCGTGCGTACTACACCCTCAACGTGCTGCGGGATGACATCGAT
  AACCCGGACCAGCGCATCAGCCAGGACGTGGAGCGATTCTGCCGGCAGCTCAGCAGCATG
  GCCAGCAAGCTCATCATCTCCCCGTTCACCCTCGTCTACTACACTTACCAGTGCTTCCAA
  AGCACAGGCTGGCTCGGGCCTGTGAGCATCTTCGGGTATTTCATCCTGGGGACCGTGGTG
  AACAAAACTTTGATGGGCCCCATTGTGATGAAGCTGGTGCATCAGGAGAAGCTGGAGGGA
  GATTTTAGGTTCAAGCACATGCAGATTCGGGTGAATGCGGAGCCTGCTGCTTTCTACAGA
  GCTGGGCATGTGGAGCACATGAGGACAGACCGCAGGCTGCAGAGACTCCTTCAGACCCAG
  AGGGAGCTGATGTCCAAGGAGCTCTGGCTGTACATCGGCATCAACACCTTTGACTATCTG
  GGCAGCATCCTGAGTTATGTTGTCATCGCAATCCCCATTTTCAGCGGGGTCTATGGAGAC
  CTGAGTCCCGCAGAGCTTAGCACCCTGGTCAGCAAGAATGCCTTTGTGTGCATCTACCTC
  ATCAGCTGCTTCACCCAGCTCATCGACCTGTCCACGACGCTCTCAGATGTGGCTGGCTAC
  ACGCACAGAATTGGGCAGCTTCGGGAGACGCTTCTGGACATGTCCCTGAAGTCACAGGAC
  TGCGAGATCCTGGGCGAGAGCGAGTGGGGCTTGGACACACCCCCAGGGTGGCCAGCGGCA
  GAGCCAGCAGACACAGCATTTCTCCTTGAGCGGGTCTCCATCTCTGCCCCCTCCTCTGAC
  AAACCCCTAATCAAGGATCTGAGCCTAAAGATCTCCGAGGGACAGAGCCTGCTCATCACA
  GGCAACACGGGCACTGGCAAGACCTCCTTGCTCCGGGTTCTAGGTGGCCTCTGGACGAGT
  ACACGGGGCTCAGTGCAGATGCTGACGGACTTTGGGCCCCATGGGGTGCTATTCCTGCCA
  CAAAAGCCATTCTTCACTGACGGGACCCTTCGGGAGCAGGTGATATATCCCCTGAAGGAG
  GTCTACCCCGACTCAGGTTCTGCCGATGATGAGAGGATCTTGAGGTTCTTGGAATTGGCA
  GGCCTGTCCAACTTGGTGGCAAGGACAGAGGGTCTGGACCAGCAGGTGGACTGGAACTGG
  TATGATGTTCTGTCCCCGGGGGAGATGCAACGGCTCTCCTTTGCCCGACTCTTCTACCTG
  CAGCCGAAGTACGCAGTGCTTGATGAAGCCACCAGTGCCCTGACAGAGGAAGTGGAGAGC
  GAGCTCTAT
  
• Restriction Sites: Please inquire
• ACCN: NM_020325
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020325.1, NP_064730.1
• RefSeq Size: 3098 bp
• RefSeq ORF: 1779 bp
• Locus ID: 5826
• Cytogenetics: 14q24.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• Gene Summary: 'The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]'
  Transcript Variant: This variant (4) contains a 171 bp insertion as a result of intron 18 retention. Inclusion of this intron results a premature stop codon and omission of the 14 amino-acid C-terminus present in transcript variant 1.