BCL2L10 (NM_020396) Human Untagged Clone

CAT#: SC304758

BCL2L10 (untagged)-Human BCL2-like 10 (apoptosis facilitator) (BCL2L10)


  "NM_020396" in other vectors (4)

Reconstitution Protocol

USD 420.00

In Stock*

Size
    • 10 ug

Product Images

Other products for "BCL2L10"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol BCL2L10
Synonyms BCL-B; bcl2-L-10; Boo; Diva
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_020396 edited
CCAAGAAAACCAGCGAAGGCCCGGCCCCCCAGCAGAGGCCGGACCATGGTTGACCAGTTG
CGGGAGCGCACCACCATGGCCGACCCGCTGCGGGAGCGCACCGAGCTGTTGCTGGCCGAC
TACCTGGGGTACTGCGCCCGGGAACCCGGCACCCCCGAGCCGGCGCCATCCACGCCCGAG
GCCGCCGTGCTGCGCTCCGCGGCCGCCAGGTTACGGCAGATTCACCGGTCCTTTTTCTCC
GCCTACCTCGGCTACCCCGGGAACCGCTTCGAGCTGGTGGCGCTGATGGCGGATTCCGTG
CTCTCCGACAGCCCCGGCCCCACCTGGGGCAGAGTGGTGACGCTCGTGACCTTCGCAGGG
ACGCTGCTGGAGAGAGGGCCGCTGGTGACCGCCCGGTGGAAGAAGTGGGGCTTCCAGCCG
CGGCTAAAGGAGCAGGAGGGCGACGTCGCCCGGGACTGCCAGCGCCTGGTGGCCTTGCTG
AGCTCGCGGCTCATGGGGCAGCACCGCGCCTGGCTGCAGGCTCAGGGCGGCTGGGATGGC
TTTTGTCACTTCTTCAGGACCCCCTTTCCACTGGCTTTTTGGAGAAAACAGCTGGTCCAG
GCTTTTCTGTCATGCTTGTTAACAACAGCCTTCATTTATCTCTGGACACGATTATTATGA
GTTTTAAAACTTTTAACCCGCTTCTACCTGCCCAACTGTGACCAACTAAATGACAGATGT
GTGAGAACAAGAACTGAGGGAAAGCACCTTCCCCCACCCCAGACGTTTTTATCTGAATGC
ATACAAGGAGTCCTGAGGTGGTGATTTGGCCAGTGTTTTAACTTGTGACAAGTACTCAGG
TGTGAGGACAAGAATGCAAATGGCTCTTCCTTGAGTGAAAGAA
Restriction Sites Please inquire     
ACCN NM_020396
ORF Size 615 bp
Insert Size 900
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The ORF of this clone has been fully sequenced and found to be a perfect match to NM_020396.2.
Reference Data
RefSeq NM_020396.2, NP_065129.1
RefSeq Size 887
RefSeq ORF 615
Locus ID 10017
Protein Families Druggable Genome, Transmembrane
Gene Summary The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1.

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.