JPH3 (NM_020655) Human Untagged Clone

CAT#: SC304792

JPH3 (untagged)-Human junctophilin 3 (JPH3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: JPH3
• Synonyms: CAGL237; HDL2; JP-3; JP3; TNRC22
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020655, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCCAGTGGGGGCAGGTTTAATTTTGACGACGGAGGGTCCTACTGTGGAGGCTGGGAGGACGGCAAGG
  CGCACGGCCATGGCGTCTGCACCGGCCCCAAGGGCCAAGGCGAATACACCGGCTCGTGGAGCCACGGCTT
  CGAGGTGCTGGGCGTCTACACCTGGCCCAGCGGCAACACGTACCAGGGCACCTGGGCGCAGGGCAAGCGC
  CACGGCATCGGCCTGGAGAGCAAGGGGAAGTGGGTGTACAAGGGCGAGTGGACGCACGGATTCAAGGGGC
  GCTACGGGGTGCGGGAGTGCGCGGGCAACGGGGCCAAATACGAAGGGACCTGGAGCAACGGGCTGCAGGA
  CGGCTACGGGACCGAGACCTACTCGGACGGAGGGACCTACCAGGGCCAGTGGGTCGGTGGCATGCGCCAG
  GGCTACGGCGTCCGGCAGAGCGTCCCGTATGGCATGGCCGCGGTCATCCGCTCACCCCTGAGGACGTCCA
  TCAACTCCCTGCGCAGCGAGCACACCAACGGCACGGCGCTGCATCCCGACGCCTCTCCGGCGGTGGCCGG
  CAGCCCGGCCGTGTCCCGCGGGGGCTTCGTGCTCGTGGCCCACAGTGACTCCGAGATCCTCAAGAGCAAG
  AAGAAGGGGCTGTTTCGGCGCTCGCTGCTGAGTGGGCTGAAGCTGCGCAAGTCGGAGTCCAAGAGCAGCC
  TGGCCAGCCAACGCAGCAAGCAGAGCTCCTTTCGCAGCGAGGCGGGCATGAGCACCGTCAGCTCCACGGC
  CAGCGACATCCACTCCACCATCAGCCTGGGCGAGGCTGAGGCCGAGCTGGCGGTCATCGAGGACGACATC
  GACGCCACCACCACCGAGACCTACGTGGGCGAGTGGAAGAACGACAAACGCTCCGGCTTCGGCGTGAGCC
  AGCGCTCGGACGGGCTCAAGTACGAGGGCGAGTGGGCCAGCAACCGGCGCCATGGCTACGGCTGCATGAC
  CTTCCCGGACGGCACCAAGGAGGAGGGCAAGTACAAGCAGAACATCCTCGTCGGCGGCAAGCGCAAGAAC
  CTCATCCCCCTGCGGGCCAGCAAGATCCGCGAGAAGGTGGACCGCGCCGTTGAGGCCGCTGAGCGGGCCG
  CCACCATCGCCAAGCAGAAGGCTGAGATCGCGGCTTCCAGGACCTCCCACTCTCGGGCAAAGGCCGAGGC
  AGCCCTCACAGCAGCTCAGAAAGCCCAGGAGGAGGCGCGGATCGCCAGGATCACTGCCAAAGAGTTCTCC
  CCTTCCTTCCAGCACCGGGAAAACGGGCTGGAGTACCAGAGGCCGAAGCGTCAGACCTCCTGTGACGACA
  TCGAGGTGCTGTCCACCGGGACACCCCTGCAGCAGGAGAGCCCCGAGCTGTACCGCAAGGGCACCACTCC
  CTCCGACCTGACCCCCGACGACAGCCCCCTGCAGAGCTTCCCCACCAGCCCCGCGGCCACCCCGCCGCCC
  GCGCCCGCCGCCAGGAACAAGGTCGCCCACTTCTCGAGGCAGGTGTCGGTGGACGAGGAGCGGGGCGGGG
  ACATCCAGATGCTCCTGGAGGGCCGGGCCGGGGACTGCGCCCGCAGCAGCTGGGGCGAGGAGCAGGCCGG
  GGGCTCCAGGGGTGTCCGCAGCGGTGCCCTGCGCGGCGGCCTGCTCGTGGATGACTTCCGCACCCGAGGT
  TCGGGCCGCAAGCAGCCCGGGAACCCCAAGCCGCGGGAGCGGCGGACGGAGTCACCCCCCGTGTTCACGT
  GGACTTCCCACCACCGGGCCAGCAACCACAGCCCCGGAGGCTCCAGGCTGCTGGAGCTGCAGGAGGAGAA
  GCTGAGCAACTACCGGATGGAGATGAAACCCTTGCTGAGGATGGAGACGCATCCCCAGAAAAGACGCTAC
  AGCAAGGGCGGCGCCTGCCGGGGCTTGGGGGACGACCACCGCCCCGAGGACCGGGGCTTCGGGGTGCAGA
  GACTGCGGTCCAAGGCCCAGAACAAGGAGAACTTCAGGCCGGCCTCCTCCGCGGAGCCCGCCGTGCAGAA
  ACTGGCGAGCCTGCGGCTGGGCGGGGCCGAGCCCCGGTTGCTGCGTTGGGACTTGACCTTCTCCCCGCCC
  CAGAAATCCTTGCCTGTCGCTCTAGAGTCCGACGAGGAGAATGGGGATGAGCTCAAGTCCAGTACGGGCT
  CAGCGCCTATCCTGGTGGTCATGGTGATCTTGCTCAACATCGGAGTCGCCATTCTGTTTATTAACTTTTT
  CATCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_020655
• ORF Size: 2247 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020655.3, NP_065706.2
• RefSeq Size: 4018
• RefSeq ORF: 2247
• Locus ID: 57338
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansion from normally 6-28 repeats to 40-59 repeats in the 3' UTR of this gene have been associated with Huntington disease-like 2 (HDL2). This gene is a member of the junctophilin gene family. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2016]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).