KCC2 (SLC12A5) (NM_020708) Human Untagged Clone

CAT#: SC304801

SLC12A5 (untagged)-Human solute carrier family 12 (potassium/chloride transporter), member 5 (SLC12A5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC12A5
• Synonyms: EIEE34; EIG14; hKCC2; KCC2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_020708 edited
  GGGCGGCCGCGAATTCGCCCTTAGAGCTACAGCGAACGAGAGAGCGGCGAAGGCGGGTAG
  AGGGGCGCGGGCGAGGCGGCGCAGCCATCCCCGGACCAGGGGCCGCGCCGCCACCATGCT
  AAACAACCTGACGGACTGCGAGGACGGCGATGGGGGAGCCAACCCGGGTGATGGCAACCC
  CAAGGAAAGCAGTCCCTTCATCAACAGCACCGACACAGAGAAGGGAAAGGAGTATGATGG
  CAAGAACATGGCCTTGTTTGAGGAGGAGATGGACACCAGCCCTATGGTGTCCTCCTTGCT
  CAGTGGCCTGGCCAACTACACCAACCTGCCCCAGGGAAGTAGGGAGCATGAAGAGGCAGA
  AAACAATGAGGGTGGAAAAAAGAAGCCGGTGCAGGCCCCACGCATGGGCACCTTCATGGG
  CGTGTACCTGCCGTGCCTGCAGAACATCTTTGGCGTCATCCTCTTCCTGCGGCTCACCTG
  GGTGGTGGGCATTGCAGGCATCATGGAGTCCTTCTGCATGGTGTTCATCTGCTGCTCCTG
  TACGATGCTCACGGCCATCTCCATGAGTGCAATTGCAACGAATGGTGTTGTGCCTGCTGG
  TGGCTCCTACTACATGATTTCCAGGTCTCTGGGCCCAGAGTTTGGGGGTGCCGTGGGCCT
  CTGCTTCTACCTGGGCACTACCTTTGCAGGAGCCATGTACATCCTGGGCACCATCGAAAT
  CCTGCTGGCTTACCTCTTCCCAGCCATGGCCATCTTCAAGGCAGAAGATGCCAGTGGGGA
  GGCAGCAGCCATGCTGAACAACATGCGTGTTTACGGCACCTGTGTGCTCACCTGCATGGC
  CACTGTGGTGTTTGTGGGTGTCAAGTATGTCAACAAGTTTGCCCTTGTCTTCCTGGGTTG
  TGTCATCCTCTCCATCCTGGCCATCTATGCTGGGGTCATCAAGTCTGCCTTCGACCCACC
  CAACTTCCCGATCTGCCTCCTGGGTAACCGCACGCTGTCTCGCCATGGCTTTGATGTCTG
  TGCCAAGCTGGCTTGGGAAGGAAATGAGACGGTGACCACACGGCTATGGGGCCTTTTCTG
  CTCCTCTCGCTTCCTCAACGCCACCTGTGATGAATACTTCACCCGAAACAATGTCACAGA
  GATCCAGGGCATCCCTGGTGCTGCCAGTGGCCTCATCAAAGAGAACCTCTGGAGCTCCTA
  CCTGACCAAGGGCGTGATTGTGGAGAGGAGTGGGATGACCTCGGTGGGCCTGGCCGATGG
  CACTCCTATCGACATGGACCACCCTTATGTCTTCAGTGATATGACCTCCTACTTCACCCT
  GCTGGTTGGCATCTACTTCCCCTCAGTCACAGGGATCATGGCTGGTTCTAACCGCTCTGG
  GGACCTGAGGGATGCCCAGAAGTCAATCCCCACTGGCACCATCCTGGCCATCGCCACCAC
  CTCTGCTGTCTACATCAGCTCCGTTGTTCTGTTTGGGGCCTGCATTGAGGGGGTCGTCCT
  GCGGGACAAGTTTGGCGAAGCTGTGAATGGCAACCTCGTGGTGGGCACTCTGGCCTGGCC
  ATCTCCATGGGTAATTGTCATCGGATCCTTCTTCTCCACCTGTGGGGCTGGGCTGCAGAG
  CCTCACGGGGGCCCCACGCCTGCTGCAGGCCATCTCGAGGGATGGCATTGTGCCCTTCCT
  GCAGGTCTTTGGCCATGGCAAGGCCAATGGAGAGCCGACCTGGGCCCTGCTCCTGACTGC
  CTGCATCTGCGAGATTGGCATCCTCATTGCATCCCTCGACGAGGTGGCCCCCATCCTCTC
  TATGTTCTTCCTGATGTGCTACATGTTTGTGAATCTGGCCTGTGCAGTGCAGACGCTGCT
  GAGGACACCCAACTGGAGGCCACGCTTTCGATATTACCACTGGACCCTCTCCTTCCTGGG
  CATGAGCCTCTGCCTGGCCCTCATGTTCATCTGCTCCTGGTATTATGCACTGGTAGCCAT
  GCTCATTGCTGGACTCATCTACAAGTACATTGAGTACCGTGGGGCAGAGAAGGAGTGGGG
  CGATGGGATACGAGGTCTGTCTCTCAGTGCGGCTCGCTATGCCCTCTTACGCCTGGAGGA
  AGGGCCCCCACACACCAAGAACTGGAGGCCACAGCTGCTGGTGCTGGTGCGTGTGGACCA
  AGACCAGAATGTGGTGCACCCCCAGCTGCTCTCACTGACCTCCCAGCTGAAGGCAGGGAA
  GGGCCTGACCATCGTGGGCTCTGTCCTTGAGGGCACCTTTCTGGAAAATCATCCACAGGC
  CCAGCGGGCAGAAGAGTCTATCAGGCGCCTGATGGAGGCAGAGAAGGTGAAGGGCTTCTG
  CCAGGTGGTGATCTCCTCCAACTTGCGTGATGGCGTGTCCCATCTGATCCAGTCCGGGGG
  CCTCGGGGGGCTGCAGCACAACACTGTGCTTGTTGGCTGGCCCCGCAACTGGCGCCAGAA
  GGAAGATCATCAGACATGGAGGAACTTCATTGAGCTGGTCCGGGAAACCACAGCTGGCCA
  CTTAGCCCTGCTGGTCACCAAGAACGTTTCCATGTTTCCTGGGAACCCTGAGCGCTTCTC
  TGAGGGCAGCATCGACGTTTGGTGGATTGTGCACGATGGAGGCATGCTCATGCTGCTGCC
  CTTCCTGCTGCGGCACCACAAGGTCTGGCGGAAGTGCAAGATGCGTATCTTCACTGTGGC
  CCAGATGGATGACAATAGCATCCAGATGAAGAAGGATCTGACCACATTTCTGTATCATTT
  ACGCATCACTGCGGAGGTCGAGGTGGTGGAGATGCATGAGAGCGACATCTCAGCTTACAC
  CTATGAGAAGACGTTGGTGATGGAGCAGCGTTCCCAGATCCTCAAACAGATGCATTTAAC
  CAAGAATGAGCGGGAGCGGGAGATCCAGAGTATCACAGATGAGTCACGAGGCTCAATCCG
  GAGAAAGAATCCAGCCAACACGCGGCTCCGCCTGAACGTCCCAGAAGAGACGGCTGGTGA
  CAGTGAAGAGAAGCCAGAGGAGGAGGTGCAGCTGATCCACGATCAGAGTGCTCCCAGCTG
  CCCCAGCAGCTCCCCGTCCCCAGGGGAGGAGCCTGAGGGGGAAGGGGAGACAGATCCGGA
  GAAGGTGCATCTCACCTGGACCAAGGACAAGTCGGTGGCAGAGAAGAATAAGGGCCCCAG
  TCCTGTCTCCTCTGAGGGCATCAAGGACTTCTTCAGCATGAAGCCGGAGTGGGAGAACTT
  GAACCAGTCCAACGTGCGGCGCATGCACACGGCCGTGCGGCTGAACGAGGTCATCGTGAA
  GAAATCCCGGGACGCCAAGCTTGTTTTGCTCAACATGCCTGGGCCTCCCCGCAACCGCAA
  TGGTGATGAAAACTACATGGAGTTTCTCGAGGTCCTCACAGAGCACCTGGACCGGGTGAT
  GCTGGTCCGCGGCGGCGGCCGCGAGGTCATCACCATCTACTCCTGAGAACCAGGACCTGC
  CACCCGGGCCCGAGCGCGCCCGGCCCGCGGCTCCGGAGCCCTCGCCGCGCCCCCCGCCGC
  TGTCACCGTTTACATACAGACCCTGTGCCCGTGTCCTGGCCCCTTACCCCGCTGCCTGAA
  GCCCGGAGGCCACGCCTGTTGGGGCTGATTCGGAGAGGGCGCCCCGCCGCGCAGAGACCA
  GAGCTCCTCAGTGCCAGTTTGGCCCCTGGGTCTTCGCTGCCCTTTTTCTAAGCCCGGCCT
  CGTCTCGCCGGAGGAGACGCTGCAATAAAGGTTGGGAGAAGGCGCGGAAAGGAGAGGAGC
  TGGGGCCTTGGGGACCCCCAGGTAGTCCATGCGGCCCATTCCTCCCCTTCCCACTCCCGC
  CGCGGTCCTCGCTCTGCGCTCCTCCGGCGCTGCTCCCTGGCTCCCGGCGGCCCGGAGGCC
  CGCGGGGTGGGAAGGCCGCGCTTGCCGTCTCCGCCGCCCCTTCTCGCCGAGCCGTGGGGC
  GCGGGCGGCCGAGCCTATACATAGTGTACAGGAGACATCGCGTGTATTTTTAACGTCCCC
  ATATTTATGTGACTAGAAGCGCAACAGACTTCTCG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020708 unedited
  NGGCGTCAAAATTTGTATACGACTCACTATAGGGCGGCCGCGATTCGCCCTTAGAGCTAC
  AGCGAACGAGAGAGCGGCGAAGGCGGGTAGAGGGGCGCGGGCGAGGCGGCGCAGCCATCC
  CCGGACAGGGGCCGCGCCGCCACCATGCTAAACAACCTGACGGACTGCGAGGACGGCGAT
  GGGGGAGCCAACCCGGGTGATGGCAACCCCAAGGAAAGCAGTCCCTTCATCAACAGCACC
  GACACAGAGAAGGGAAAGGAGTATGATGGCAAGAACATGGCCTTGTTTGAGGAGGAGATG
  GACACCAGCCCTATGGTGTCCTCCTTGCTCAGTGGCCTGGCCAACTACACCAACCTGCCC
  CAGGGAAGTAGGGAGCATGAAGAGGCAGAAAACAATGAGGGTGGAAAAAAGAAGCCGGTG
  CAGGCCCCACGCATGGGCACCTTCATGGGCGTGTACCTGCCGTGCCTGCAGAACATCTTT
  GGCGTCATCCTCTTCCTGCGGCTCACCTGGGTGGTGGGCATTGCAGGCATCATGGAGTCC
  TTCTGCATGGTGTTCATCTGCTGCTCCTGTACGATGCTCACGGCCATCTCCATGAGTGCA
  ATTGCAACGAATGGTGTTGTGCCTGCTGGTGGCTCCTACTACATGATTTCCAGGTCTCTG
  GGCCCAGAGTTTGGGGGTGCCGTGNGCCTCTGCTTCTACCTGGGCACTACCTTTGCAGGA
  GCCATGTACATCCTGGGCACCATCGAAATCCTGCTGGCTTACCTCTTCCCAGCCATGGCC
  ATCTTCAAGGCAAAGATGCCAGTGGGGAGGCCACACCCATGCTGAACACATGCGTGTTTA
  CGGCACCTGTGTGCTCACCTGCATGGCCACTGGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020708 unedited
  NCATTGGNGATGGCACTTCCAGGNCCAGNATAGCACTGGGGNAGGGTCACAGGGNAGCCA
  CCCGGGATCTGTTCAGGAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTT
  TTTTTTTTTTTAAGGGTATAATAAAATTATTTTTATTGCATTTTGTGCAGACGGGAGTCT
  AAAAAAGTAATACAGTAAAAGCCATAAAGCATTAAATGGGAGCATTCAACAATAAAGGAA
  AGAACCAACCCTCTCCTTTTCATATTGGCACAAAGAACACAAGATCAATACTGAGGCAGG
  ATGCGGCATACTGAACACTTACACTGAAAATTAAAGGCAGGCCTAATAATAATAGCAGTA
  ATAGTAATAAATACTCTTGATTTGGTTTGCAACCTCTCCTATTTACAAGGGTTTTCAACT
  TCATTGCATTGCCCTGCACATAGATCATCTAAAACAAAAGCAACACTAGTTATCACTACA
  AGGCTATTGAAATATTGCACTCAGAATAAAAGTCACTTGAATGGACATGAAACATCTAAC
  TACAGTGATTATAAAGATAACTTGATGAATGACTTGTGATAACATTCATAACAAATATTG
  CACATGTAGCACAGAAAATTTGGGTTTTTGTTGTGGGATGTCTGTTTCATCAACGGAAAC
  TTTGCTCTTGCCAACCAGACAATCTGGGCCCAGATAGTGCAACTTTGGGTCCCTAATTGA
  TGTTGATACAGCCCCCTTTCTGCACAGCCCATCACATCAGCTCTGGAATATTCAGGCCCC
  CANAAAGGCAGACCTGGCTGTGGTGTTCACAAGGAGGGCTACTGAAAGATGCAGGGGCCT
  GGTGTCTTAACACCTCCAGCTCCCTTGTTGAGTACTTGAAAGAATCTATCATGCCCC
  
• Restriction Sites: Please inquire
• ACCN: NM_020708
• ORF Size: 3351 bp
• Insert Size: 6000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_020708.3, NP_065759.1
• RefSeq Size: 6059
• RefSeq ORF: 3351
• Locus ID: 57468
• Protein Families: Transmembrane
• Gene Summary: K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (2, also known as KCC2b) has a distinct N-terminus and is shorter than isoform 1.