Prol1 (OPRPN) (NM_021225) Human Untagged Clone

CAT#: SC304924

PROL1 (untagged)-Human proline rich, lacrimal 1 (PROL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: OPRPN
• Synonyms: BPLP; opiorphin; PRL1; PROL1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021225 edited
  CTTTCTCTTCTTGGACTTTTAAATTGTGGCTACCTAAATTGAGTATCTGGCAAGAGTAAG
  ATTAAGCAGTAATTTGTTCCAAAGAAGAATCTTCTACCAAGGAGCAACTTTAAAGAATGA
  AATTAACTTTCTTCTTGGGCCTGTTGGCTCTTATTTCATGTTTCACACCCAGTGAGAGTC
  AAAGATTCTCCAGAAGACCATATCTACCTGGCCAGCTGCCACCACCTCCACTCTACAGGC
  CAAGATGGGTTCCACCAAGTCCCCCACCTCCCTATGACTCAAGACTTAATTCACCACTTT
  CTCTTCCCTTTGTCCCAGGGCGAGTTCCACCATCTTCTTTCTCTCGATTTAGCCAAGCAG
  TCATTCTATCTCAACTCTTTCCATTGGAATCTATTAGACAACCTCGACTCTTTCCGGGTT
  ATCCAAACCTACATTTCCCACTAAGACCTTACTATGTAGGACCTATTAGGATATTAAAAC
  CCCCATTTCCTCCTATTCCTTTTTTTCTTGCTATTTACCTTCCTATCTCTAACCCTGAGC
  CCCAAATAAACATCACCACCGCAGATACAACAATCACCACAAATCCCCCCACCACTGCAA
  CAGCAACCACCAGCACTTCCACAAAACCCACAATGACGATCAGCTCCTCAACAGTACCTA
  TCTCTTCAACACCAGAGCCTGCCACCTCCATATCAGCAGCAACCCCCGCAGCATCTACTG
  AAAATACTACTCAAATTCTCGCCAACCGTCCTCACACAGTATTGCTCAATGCCACTGTCC
  AAGTTACGACTTCCAACCAAACTATATTAAGCAGCCCAGCCTTTAAAAGTTTTTGGCAAA
  AACTCTTTGCCATTTTTGGTTGAACATGCAATAAATGATATTTTCCAAACTGCTCTGATA
  TCTTAGAAGAAATAAACTGCAATGATTTTGATGGAACCAACCCTGATCTAACCAGCACAC
  TAAATAAAGTATTTGAGCAATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021225 unedited
  GAGGATTAAGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCCATTACGGCCGGGGCT
  TTCTCTTCTTGGACTTTTAAATTGTGGCTACCTAAATTGAGTATCTGGCAAGAGTAAGAT
  TAAGCAGTAATTTGTTCCAAAGAAGAATCTTCTACCAAGGAGCAACTTTAAAGAATGAAA
  TTAACTTTCTTCTTGGGCCTGTTGGCTCTTATTTCATGTTTCACACCCAGTGAGAGTCAA
  AGATTCTCCAGAAGACCATATCTACCTGGCCAGCTGCCACCACCTCCACTCTACAGGCCA
  AGATGGGTTCCACCAAGTCCCCCACCTCCCTATGACTCAAGACTTAATTCACCACTTTCT
  CTTCCCTTTGTCCCAGGGCGAGTTCCACCATCTTCTTTCTCTCGATTTAGCCAAGCAGTC
  ATTCTATCTCAACTCTTTCCATTGGAATCTATTAGACAACCTCGACTCTTTCCGGGTTAT
  CCAAACCTACATTTCCCACTAAGACCTTACTATGTAGGACCTATTAGGATATTAAAACCC
  CCATTTCCTCCTATTCCTTTTTTTCTTGCTATTTACCTTCCTATCTCTAACCCTGAGCCC
  CAAATAAACATCACCACCGCAGATACAACAATCACCACAAATCCCCCCACCACTGCAACA
  GCAACCACCAGCACTTCCACAAAACCCACAATGACGATCAGCTCCTCAACAGTACCTATC
  TCTTCAACACCAGAGCCTGCCACCTCCATATCAGCAGCAACCCCCGCAGCATCTACTGAA
  AATACTACTCAAATTCTCGCCAACCGTCCTCACACAGTATTGCTCAATGCCACTGTCCAA
  GTTACGACTTCCAACCAAACTATTATTAAGCAGCCCAGCCTTTAAAGGTTTTGCAAAACT
  CTTTGCATTTTGTTGACATGCAATAAATGATAATTTTCCAACTGCTTCTGATATTCTTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_021225
• ORF Size: 747 bp
• Insert Size: 1000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_021225.4, NP_067048.4
• RefSeq Size: 1060
• RefSeq ORF: 747
• Locus ID: 58503
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
  Transcript Variant: This variant (1) encodes the longer isoform (1).