UCP1 (NM_021833) Human Untagged Clone

CAT#: SC304965

UCP1 (untagged)-Human uncoupling protein 1 (mitochondrial, proton carrier) (UCP1), nuclear gene encoding mitochondrial protein


  "NM_021833" in other vectors (6)

Reconstitution Protocol

USD 660.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol UCP1
Synonyms SLC25A7; UCP
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_021833 edited
AGAGCAAGGGAAAGGAACTTCCTCCACCTTCGGGGCTGGAGCCCTTTTCCTCTGCATCTC
CAGTCTCTGAGTGAAGATGGGGGGCCTGACAGCCTCGGACGTACACCCGACCCTGGGGGT
CCAGCTCTTCTCAGCTGGAATAGCGGCGTGCTTGGCGGACGTGATCACCTTCCCGCTGGA
CACGGCCAAAGTCCGGCTCCAGGTCCAAGGTGAATGCCCGACGTCCAGTGTTATTAGGTA
TAAAGGTGTCCTGGGAACAATCACCGCTGTGGTAAAAACAGAAGGGCGGATGAAACTCTA
CAGCGGGCTGCCTGCGGGGCTTCAGCGGCAAATCAGCTCCGCCTCTCTCAGGATCGGCCT
CTACGACACGGTCCAGGAGTTCCTCACCGCAGGGAAAGAAACAGCACCTAGTTTAGGAAG
CAAGATTTTAGCTGGTCTAACGACTGGAGGAGTGGCAGTATTCATTGGGCAACCCACAGA
GGTCGTGAAAGTCAGACTTCAAGCACAGAGCCATCTCCACGGAATCAAACCTCGCTACAC
GGGGACTTATAATGCGTACAGAATAATAGCAACAACCGAAGGCTTGACGGGTCTTTGGAA
AGGGACTACTCCCAATCTGATGAGAAGTGTCATCATCAATTGTACAGAGCTAGTAACATA
TGATCTAATGAAGGAGGCCTTTGTGAAAAACAACATATTAGCAGATGACGTCCCCTGCCA
CTTGGTGTCGGCTCTTATCGCTGGATTTTGCGCAACAGCTATGTCCTCCCCGGTGGATGT
AGTAAAAACCAGATTTATTAATTCTCCACCAGGACAGTACAAAAGTGTGCCCAACTGTGC
AATGAAAGTGTTCACTAACGAAGGACCAACGGCTTTCTTCAAGGGGTTGGTACCTTCCTT
CTTGCGACTTGGATCCTGGAACGTCATTATGTTTGTGTGCTTTGAACAACTGAAACGAGA
ACTGTCAAAGTCAAGGCAGACTATGGACTGTGCCACATAA
>OriGene 5' read for NM_021833 unedited
NNNGGTTGAGTCAGATTTGTATACGACTCATATAGGCGGCCGCGAATTCCCCTTCCCAGA
CAGGGAAAGAACTTCCTCCACCTTCGGGGCTGGAGCCCTTTTCCTCTGCATCTCCAGTCT
CTGAGTGAAGATGGGGGGCCTGACAGCCTCGGACGTACACCCGACCCTGGGGGTCCAGCT
CTTCTCAGCTGGAATAGCGGCGTGCTTGGCGGACGTGATCACCTTCCCGCTGGACACGGC
CAAAGTCCGGCTCCAGGTCCAAGGTGAATGCCCGACGTCCAGTGTTATTAGGTATAAAGG
TGTCCTGGGAACAATCACCGCTGTGGTAAAAACAGAAGGGCGGATGAAACTCTACAGCGG
GCTGCCTGCGGGGCTTCAGCGGCAAATCAGCTCCGCCTCTCTCAGGATCGGCCTCTACGA
CACGGTCCAGGAGTTCCTCACCGCAGGGAAAGAAACAGCACCTAGTTTAGGAAGCAAGAT
TTTAGCTGGTCTAACGACTGGAGGAGTGGCAGTATTCATTGGGCAACCCACAGAGGTCGT
GAAAGTCAGACTTCAAGCACAGAGCCATCTCCACGGAATCAAACCTCGCTACACGGNGAC
TTATAATGCGTACAGAATAATAGCAACAACCGAAGGCTTGACGGGTCTTTGGAAAGGGAC
TACTCCCAATCTGATGAGAAGTGTCATCATCAATTGTACAGAGCTAGTAACATATGATCT
AATGAANNGAGCCTTTGTGAAAACAACATATTAGCAGATGACGTCCCCTGCCACTTGGTG
TCGGCTCTTATCGCTGGNATTTGCGCAACAGCTATGTCCCTCCCCGTGGATGTAGTAAAA
ACCCAGATTATTAATCTCN
Restriction Sites Please inquire     
ACCN NM_021833
Insert Size 1000 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_021833.3, NP_068605.1
RefSeq Size 1047 bp
RefSeq ORF 924 bp
Locus ID 7350
Cytogenetics 4q31.1
Protein Families Druggable Genome
Protein Pathways Huntington's disease, PPAR signaling pathway
Gene Summary 'Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.