ULBP1 (NM_025218) Human Untagged Clone

CAT#: SC305245

ULBP1 (untagged)-Human UL16 binding protein 1 (ULBP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ULBP1
• Synonyms: N2DL-1; NKG2DL1; RAET1I
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_025218 edited
  GGGAACCATCAGCGCCTCCTGTCCACGGAGCTCCAGGTCTACAATGGCAGCGGCCGCCAG
  CCCCGCGTTCCTTCTGTGCCTCCCGCTTCTGCACCTGCTGTCTGGCTGGTCCCGGGCAGG
  ATGGGTCGACACACACTGTCTTTGCTATGACTTCATCATCACTCCTAAGTCCAGACCTGA
  ACCACAGTGGTGTGAAGTTCAAGGCCTGGTGGATGAAAGGCCTTTTCTTCACTATGACTG
  TGTTAACCACAAGGCCAAAGCCTTTGCTTCTCTGGGGAAGAAAGTCAATGTCACAAAAAC
  CTGGGAAGAACAAACTGAAACACTAAGAGACGTGGTGGATTTCCTTAAAGGGCAACTGCT
  TGACATTCAAGTGGAGAATTTAATACCCATTGAGCCCCTCACCCTGCAGGCCAGGATGTC
  TTGTGAGCATGAAGCCCATGGACACGGCAGAGGATCTTGGCAGTTCCTCTTCAATGGACA
  GAAGTTCCTCCTCTTTGACTCAAACAACAGAAAGTGGACAGCACTTCATCCTGGAGCCAA
  GAAGATGACAGAGAAGTGGGAGAAGAACAGGGATGTGACCATGTTCTTCCAGAAGATTTC
  ACTGGGGGATTGTAAGATGTGGCTTGAAGAATTTTTGATGTACTGGGAACAAATGCTGGA
  TCCAACAAAACCACCCTCTCTGGCCCCAGGCACAACCCAACCCAAGGCCATGGCCACCAC
  CCTCAGTCCCTGGAGCCTTCTCATCATCTTCCTCTGCTTCATTCTAGCTGGCAGATGAGG
  AGAGTTGTTTAGAGTGACAGGTGGAAAGTGATATCAAGAAGCCTCTGTTAGCCTGGTCTG
  GGTCCTGCTCTCCCTTCAGGGAGGCCGCCTGTCTACTCACCACTGTGCCTTTCTGGAAAG
  CAGGAGTTCAAGCCTTAGCAAGCCCAGAGGCCCCCAGCAGACGATGAGGACATTGTCGGC
  TCAACATCTCAGGCCACTCATTACCTTCGCTCATGATCCCAGCAGCCATTTTTCTTAACA
  CCTTCTGCCACTTTCTGTCGGTGCTAATGGATGGAACTCCTGCACAAGTTTTAACTGAAC
  AAGAAATCCCAGCAAAAGGCATTTTTTTTTCTACTTCTTTGATTGTAGAAAAGCAGACAC
  TTCTCTGAAACATGACCTTATTCTTCCAAACAGTATCGCTAGTAAAATAGCATGCTGGAC
  TTCAGACCTCAGGGATCCTTTTGATGCACTGACCAGGAATTGTGATAATCCTTTTCATTT
  TTATGGCTTTTTACAGTTTCTCATTCTGTCAACCATATTGAAGTGAAGTGGCATAGTCTT
  CACTCACTGTAATCTCCAGCTCCTGGGCTCAAGTGATCCTCTAGACTCAGCCTCTAGAAT
  AGCTGGGACTACAGGCACATGCCACCAGGACTGGCAAACTGTTTTATTTTTAGGTAGAGG
  TAGGGTCTTCCTATGTTGCCCAGGATGGTCTTCAAATCTTGGTCTCGAGCAATGCTACCA
  CCTTGGCCTCCCAATGCTCTGGGATTACAGACATGAACCACAGTGCCTGTTGTAGAAATT
  TTTAATTATTTAATATGAAAATATTACATTCATGATTATTTTATTTAGTAAATAAAATAA
  TAGAGAGCCCAGAAATCAACCTGCACACCTACCGCCATCTAATCTTCAATAGAAATGGGC
  AATGTGGGAAAGACTCCCTATTCGAAAATTAGTGCTGGAATATCTGGCCAACCATATGCA
  GAAGAATGAAACTGAACCCCTACTTCTCCCCATATATGTAAAATAATTCAATATGGATGA
  AAGATTTAAATATAAGTACTAAAACTGTAAAAATCCTGGAATATAACCTAAGAAATACCA
  ATGTGGACATAGGGCCTGGCAAAGATTTCATGAAGAAGACACTAAAAACAATTGCAACAA
  AAACAGAAATTGACAAATGGGGCCTCATTAAACTAAAGAGCTTCTGCACAGAAAAAGAAA
  CTAGCAACACAGTAAACAGACAGCCTGTAGAATGGGGAAAACTATTTGCAAACTCTGCAT
  CTGATGAAGGTCCAATATCCAGAATCTACAAGGAACTTAAACAATTCAACAAGCAAGAAG
  AAAAAACCCAATTAAAATTGGGCAAAGGCATGAACAGACACTTTTCAAAAGAAGACCTAC
  AATTGGCCAACAAACATGAAAAAATGCTCAGTATCACTAATCATCAGATAAGTGCAAATC
  AAAACTGCAATGAGTTACCATCTCTTACCAGTCACAAAGTCAGAGATGGTGGTGAGGCTG
  CAGAGCAAAAGAAACAGACACTGTTGGTGGGAAAGCAAACTTGTTCAGCCACTATGGAAA
  GCAGTTTGGAGATTTCTCCAAGAACTTAAAATAGAACTACCATTCAATCCCGCAATCCCA
  CTACTCGGGATATACCCACAGGAAAAGAATTCATTTTATCAAAAAGACACCTGCACCAAT
  ATGTTCATTACAGTGCTATTCTCACCAGCAAGGACAGAGAATCAATCTAAGTGCCCAACA
  ACAGTAAATTCAATGAAAAAAAATGTGGTACATAGATACGATGGAAAACTATGCAGCCAT
  GAAACACAAGAAAATCATGTCCTTTTCAGCAACATGGATGCAACTAGAGGCTATTATCCT
  AAGCAACCTAATGCAAGAACAGAAAACCACATACTGCATCTTCCCATTGGAAAGTGGCAG
  CTAAACATTAAATTCGCATGAACCACAGATGCTGGAGATCACCAGACCGGGGAGAGAAGA
  GGGGCACCTGGGCTGAAAAACACACCTGTTGGGTATCATGCTTACTGTCTGGGCGATGGG
  ATCATTGGGACACCAAGCCTCAGCTTCTCAAATTCTACCCATGTAACAAACCTGTATATG
  TACCTTGTATTATATAGGTTGAAATTAAAGATGAATAAATAAAATAAAATGACACAAGGC
  CAAAAACAAATGGGTTTAACTGACCAGAGCGAGAGAACTCTGCACTATGAACCCAAACCC
  AGCTCAAAAAGATAAAATCTAGTCATTTAAGATAATCATAAGTTGTATGATGATAATTGT
  ATAAAAATTTGTATGATGATAATTGTATAATAATTATACATGAAAGTGCCAAAACCCTAC
  AATTAAACACTGTATAATGGAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_025218
• ORF Size: 735 bp
• Insert Size: 3100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_025218.2.

Reference Data

• RefSeq: NM_025218.2, NP_079494.1
• RefSeq Size: 3160
• RefSeq ORF: 735
• Locus ID: 80329
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity
• Gene Summary: The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
  Transcript Variant: This variant (1) encodes the longer isoform (1).