Melanopsin (OPN4) (NM_033282) Human Untagged Clone

CAT#: SC305606

OPN4 (untagged)-Human opsin 4 (OPN4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: OPN4
• Synonyms: MOP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_033282 edited
  GCTCCCTGTGCCCTTGACTTCTCTGTGGGCTCGAGCAAGGACCATCCCAACTCAGGATGA
  ACCCTCCTTCGGGGCCAAGAGTCCTGCCCAGCCCAACCCAAGAGCCCAGCTGCATGGCCA
  CCCCAGCACCACCCAGCTGGTGGGACAGCTCCCAGAGCAGCATCTCCAGCCTGGGCCGGC
  TTCCATCCATCAGTCCCACAGCACCTGGGACTTGGGCTGCTGCCTGGGTCCCCCTCCCCA
  CGGTTGATGTTCCAGACCATGCCCACTATACCCTGGGCACAGTGATCTTGCTGGTGGGAC
  TCACGGGGATGCTGGGCAACCTGACGGTCATCTATACCTTCTGCAGGAGCAGAAGCCTCC
  GGACACCTGCCAACATGTTCATTATCAACCTCGCGGTCAGCGACTTCCTCATGTCCTTCA
  CCCAGGCCCCTGTCTTCTTCACCAGTAGCCTCTATAAGCAGTGGCTCTTTGGGGAGACAG
  GCTGCGAGTTCTATGCCTTCTGTGGAGCTCTCTTTGGCATTTCCTCCATGATCACCCTGA
  CGGCCATCGCCCTGGACCGCTACCTGGTAATCACACGCCCGCTGGCCACCTTTGGTGTGG
  CGTCCAAGAGGCGTGCGGCATTTGTCCTGCTGGGCGTTTGGCTCTATGCCCTGGCCTGGA
  GTCTGCCACCCTTCTTCGGCTGGAGCGCCTACGTGCCCGAGGGGTTGCTGACATCCTGCT
  CCTGGGACTACATGAGCTTCACGCCGGCCGTGCGTGCCTACACCATGCTTCTCTGCTGCT
  TCGTGTTCTTCCTCCCTCTGCTTATCATCATCTACTGCTACATCTTCATCTTCAGGGCCA
  TCCGGGAGACAGGACGGGCTCTCCAGACCTTCGGGGCCTGCAAGGGCAATGGCGAGTCCC
  TGTGGCAGCGGCAGCGGCTGCAGAGCGAGTGCAAGATGGCCAAGATCATGCTGCTGGTCA
  TCCTCCTCTTCGTGCTCTCCTGGGCTCCCTATTCCGCTGTGGCCCTGGTGGCCTTTGCTG
  GGTACGCACACGTCCTGACACCCTACATGAGCTCGGTGCCAGCCGTCATCGCCAAGGCCT
  CTGCAATCCACAACCCCATCATTTACGCCATCACCCACCCCAAGTACAGGGTGGCCATTG
  CCCAGCACCTGCCCTGCCTGGGGGTGCTGCTGGGTGTATCACGCCGGCACAGTCGCCCCT
  ACCCCAGCTACCGCTCCACCCACCGCTCCACGCTGACCAGCCACACCTCCAACCTCAGCT
  GGATCTCCATACGGAGGCGCCAGGAGTCCCTGGGCTCGGAGAGTGAGGTGGGCTGGACAC
  ACATGGAGGCAGCAGCTGTGTGGGGAGCTGCCCAGCAAGCAAATGGGCGGTCCCTCTACG
  GTCAGGGTCTGGAGGACTTGGAAGCCAAGGCACCCCCCAGACCCCAGGGACACGAAGCAG
  AGACTCCAGGGAAGACCAAGGGGCTGATCCCCAGCCAGGACCCCAGGATGTAGGACGCCC
  ACTGGCTCTCCCTTTCTTCTGAGACACATCCAGCCCCCCCACGTCTCCCTCATATACACA
  GACCCAGGATTATGCTGTGAGCCTGCAGGCTTTGGAAGTGGCCCTGTCACCCGTGCTGCA
  CGGGATTCACAGCCCCAGCCCCATGGCCCCTCTCCACACCTCAAAACTCCTGCCCCATAA
  CGTCCTCCGCATCCACTTTCCAGCTCAGCAGCCGCACCCGAGGCTCAGCCTGAGGGGTGT
  GTGCCCAGGCCCTCCCACTTCCCGAGTTGTCTGCCTCTCCTCAAATGCTGTGTGCTGCAA
  TTGTCCAGGCGATGACAATGGTGATGGCTCCAGAGAACACACCAGCTATTTATGAGCCTC
  TGCCCCCAGGCTGGGCCTGTCACTGGCATAGGAAGGCCA
  
• Restriction Sites: Please inquire
• ACCN: NM_033282
• ORF Size: 1437 bp
• Insert Size: 1900
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_033282.2.

Reference Data

• RefSeq: NM_033282.2, NP_150598.1
• RefSeq Size: 2308
• RefSeq ORF: 1437
• Locus ID: 94233
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).